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Guise

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Guise Flights as Low as $243

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Air France
Thu, May 7 - Mon, May 11
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$243 Roundtrip, found 2 hours ago
$243
Roundtrip
found 2 hours ago
Select Air France flight, departing Thu, May 7 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Mon, May 11, priced at $243 found 2 hours ago
Air France
Tue, Apr 21 - Tue, Apr 28
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$259 Roundtrip, found 2 days ago
$259
Roundtrip
found 2 days ago
Select Air France flight, departing Tue, Apr 21 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Tue, Apr 28, priced at $259 found 2 days ago
Air France
Wed, Apr 29 - Mon, May 4
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$276 Roundtrip, found 13 hours ago
$276
Roundtrip
found 13 hours ago
Select Air France flight, departing Wed, Apr 29 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Mon, May 4, priced at $276 found 13 hours ago
Air France
Tue, May 5 - Mon, May 11
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$276 Roundtrip, found 14 hours ago
$276
Roundtrip
found 14 hours ago
Select Air France flight, departing Tue, May 5 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Mon, May 11, priced at $276 found 14 hours ago
Air France
Sat, Apr 18 - Mon, May 4
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$279 Roundtrip, found 2 days ago
$279
Roundtrip
found 2 days ago
Select Air France flight, departing Sat, Apr 18 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Mon, May 4, priced at $279 found 2 days ago
Air France
Wed, May 6 - Wed, May 6
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$282 Roundtrip, found 22 hours ago
$282
Roundtrip
found 22 hours ago
Select Air France flight, departing Wed, May 6 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Wed, May 6, priced at $282 found 22 hours ago
Air France
Thu, May 7 - Mon, May 11
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$287 Roundtrip, found 2 hours ago
$287
Roundtrip
found 2 hours ago
Select Air France flight, departing Thu, May 7 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Mon, May 11, priced at $287 found 2 hours ago
Air France
Sat, Apr 18 - Mon, May 4
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$292 Roundtrip, found 2 days ago
$292
Roundtrip
found 2 days ago
Select Air France flight, departing Sat, Apr 18 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Mon, May 4, priced at $292 found 2 days ago
Air France
Thu, May 7 - Fri, May 15
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$293 Roundtrip, found 22 hours ago
$293
Roundtrip
found 22 hours ago
Select Air France flight, departing Thu, May 7 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Fri, May 15, priced at $293 found 22 hours ago
Air France
Tue, May 5 - Wed, May 6
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$294 Roundtrip, found 1 hour ago
$294
Roundtrip
found 1 hour ago
Select Air France flight, departing Tue, May 5 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Wed, May 6, priced at $294 found 1 hour ago
Air France
Sun, Apr 19 - Mon, May 4
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$298 Roundtrip, found 4 hours ago
$298
Roundtrip
found 4 hours ago
Select Air France flight, departing Sun, Apr 19 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Mon, May 4, priced at $298 found 4 hours ago
Air France
Wed, May 6 - Mon, May 11
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$303 Roundtrip, found 18 hours ago
$303
Roundtrip
found 18 hours ago
Select Air France flight, departing Wed, May 6 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Mon, May 11, priced at $303 found 18 hours ago
Air France
Tue, May 5 - Sat, May 9
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$309 Roundtrip, found 14 hours ago
$309
Roundtrip
found 14 hours ago
Select Air France flight, departing Tue, May 5 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Sat, May 9, priced at $309 found 14 hours ago
Air France
Thu, May 7 - Mon, May 11
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$316 Roundtrip, found 2 hours ago
$316
Roundtrip
found 2 hours ago
Select Air France flight, departing Thu, May 7 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Mon, May 11, priced at $316 found 2 hours ago
Air France
Wed, Apr 29 - Fri, May 1
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$322 Roundtrip, found 4 days ago
$322
Roundtrip
found 4 days ago
Select Air France flight, departing Wed, Apr 29 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Fri, May 1, priced at $322 found 4 days ago
Air France
Thu, May 7 - Thu, May 14
OPO
Dr. Francisco de Sa Carneiro
XDB
Lille Europe TGV Train Station
$325 Roundtrip, found 1 day ago
$325
Roundtrip
found 1 day ago
Select Air France flight, departing Thu, May 7 from Dr. Francisco de Sa Carneiro to Lille Europe TGV Train Station, returning Thu, May 14, priced at $325 found 1 day ago

Cheap Flights to Guise

Fall in love at first flight with your vacation to Guise by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Guise on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Guise, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Guise

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Guise with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the XLN airport.

What is the cheapest month to fly to Guise?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Guise are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Guise?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Guise.

What airport is best to fly into Guise?

When you’re planning your trip to Guise, convenience is the name of the game. Luckily, Guise Lesquin Airport is nearby so you can deplane and get going on checking off everything on your Guise must-do list.

How much are flights to Guise?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Guise on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $243, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Guise?

The trick to saving a stack of cash on your flight to Guise? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $243 right now, why wait?

Guise Flight Information
Destination airport
Lille Europe TGV Train Station
Destination airport IATA code
XDB
Roundtrip price
$243

Last Minute Hotel Deals in Guise

B&B HOTEL Saint-Quentin

B&B HOTEL Saint-Quentin

2 out of 5
ZAC de la Vallée Saint-Quentin
Stay at this hotel in Saint-Quentin. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Royal Kids Saint Quentin and Musée Antoine ...
8.2/10 Very Good! (246 reviews)
Reflective of the excellent price, clean and adequate for a stopover en route to the Channel Tunnel. Restuarant and bakery within walking distance. Beds comfy and family room generously sized as always. Just a bit of a dated hotel compared to some B&Bs but perfectly fine for a stopover and price ...

Reviewed on Apr 12, 2026

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B&B HOTEL Saint-Quentin
The Originals Boutique, Hôtel 3 étoiles Les Coulisses du Théâtre

The Originals Boutique, Hôtel 3 étoiles Les Coulisses du Théâtre

3 out of 5
8 Rue de la Comédie Saint-Quentin Haut-de-France
Stay at this hotel in Saint-Quentin. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Popular attractions Théâtre Jean-Vilar and Butterfly Museum ...
9.8/10 Exceptional! (84 reviews)
The room and bathroom were a fair size. The decoration was OK but too much black made it quite difficult to see in the very subdued lighting. There were some weak details such as no hangers for trousers, only 2 coffee pods (very mean) and unusable plug sockets behind curtains. The bathroom was excellent ...

Reviewed on Mar 28, 2026

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The Originals Boutique, Hôtel 3 étoiles Les Coulisses du Théâtre
Campanile Saint Quentin

Campanile Saint Quentin

3 out of 5
ZAC de la Vallée Rue Charles - Naudin Saint-Quentin Aisne
Book a stay at this business-friendly hotel in Saint-Quentin. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Royal Kids Saint ...
8/10 Very Good! (456 reviews)
Used just for bed en-route

Reviewed on Mar 15, 2026

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Campanile Saint Quentin
ibis Styles Saint-Quentin

ibis Styles Saint-Quentin

3 out of 5
Av. Archimede Za Du Bois de la Chocque Saint-Quentin Aisne
Book a stay at this business-friendly hotel in Saint-Quentin. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Royal Kids Saint ...
9/10 Wonderful! (112 reviews)
Everything you could want for breakfast. Everything was fresh and well presented. Plenty of secure parking. Restaurants close by 3 minutes walking. Nice area. Highly Recommend. Perfect stop over heading south.

Reviewed on Apr 10, 2026

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ibis Styles Saint-Quentin
Sure Hotel by Best Western Saint-Quentin Ouest Le pot d'étain

Sure Hotel by Best Western Saint-Quentin Ouest Le pot d'étain

3 out of 5
29 Route Nationale Holnon Aisne
Book a stay at this business-friendly hotel in Holnon. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Royal Kids Saint Quentin ...
8.4/10 Very Good! (194 reviews)
Spent night to break up drive from UK to alps, clean hotel and very friendly staff.

Reviewed on Apr 11, 2026

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Sure Hotel by Best Western Saint-Quentin Ouest Le pot d'étain
Best Western Plus Le Picardy

Best Western Plus Le Picardy

4 out of 5
6 Rue Dachery Saint-Quentin HDF
Stay at this hotel in Saint-Quentin. Enjoy breakfast (surcharge), parking (surcharge), and a 24-hour front desk. Popular attractions Le Splendid and Butterfly ...
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Best Western Plus Le Picardy
Logis Hôtel& Appartements Le Florence

Logis Hôtel& Appartements Le Florence

2 out of 5
42 Rue Emile Zola Saint-Quentin Aisne
Book a stay at this business-friendly hotel in Saint-Quentin. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful ...
9/10 Wonderful! (418 reviews)
Excellent breakfast with fresh local products and a great variety.

Reviewed on Apr 1, 2026

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Logis Hôtel& Appartements Le Florence
ibis budget Saint-Quentin Centre Gare

ibis budget Saint-Quentin Centre Gare

2 out of 5
84 Rue Michelet Saint-Quentin
Stay at this hotel in Saint-Quentin. Enjoy free WiFi, breakfast (surcharge), and free bicycles on site. Popular attractions Le Splendid and Isle Beach are located ...
8.8/10 Excellent! (279 reviews)
Staff very welcoming, rooms clean. Arrived at 04:30am due to bad traffic, no issues checking in. Only stayed for 5 hours but beds were comfortable. Had a triple room, double bed with bunk over. Then off on our journey. We had a lovely continental breakfast.

Reviewed on Feb 25, 2026

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ibis budget Saint-Quentin Centre Gare
See all 259 properties in Guise
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.