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Mississippi River Vacation Packages

Mississippi River Flight + Hotel Packages

Fairmont Chicago at Millennium Park Gold Experience
Trump International Hotel & Tower Chicago
Le Pavillon New Orleans
Hilton Garden Inn Chicago Downtown South Loop
Le Méridien New Orleans
The Peninsula Chicago
Dauphine Orleans Hotel
Hotel Le Marais
Maison Dupuy Hotel
Park Hyatt Chicago
The Gwen, a Luxury Collection Hotel, Michigan Avenue Chicago
Hilton New Orleans Riverside
Prices and availability subject to change. Additional terms may apply.

3-4 Night Vacations in Mississippi River

Fairmont Chicago at Millennium Park Gold Experience
Trump International Hotel & Tower Chicago
Level Chicago – Old Town
Hilton New Orleans Riverside
Prices and availability subject to change. Additional terms may apply.

5-7 Night Vacations in Mississippi River

21c Museum Hotel Chicago
The Peninsula Chicago
Hilton Garden Inn Chicago Downtown South Loop
Fairmont Chicago at Millennium Park
Prices and availability subject to change. Additional terms may apply.

Mississippi River Last Minute Hotel Deals

Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport
2.5 out of 5
10810 Pear Tree Ln, St. Ann, MO
Stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Pear Tree Inn St. Louis Airport
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the convenient ...
Hollywood Casino & Hotel St. Louis
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful ...
Clayton Plaza Hotel & Extended Stay
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
Stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
Hyatt Regency St. Louis at The Arch
Best Western St. Louis-Kirkwood Route 66
Best Western St. Louis-Kirkwood Route 66
2.5 out of 5
1200 S Kirkwood Road, Kirkwood, MO
Stay at this business-friendly hotel in Kirkwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Best Western St. Louis-Kirkwood Route 66
Renaissance St. Louis Airport Hotel
Renaissance St. Louis Airport Hotel
4 out of 5
9801 Natural Bridge Road, St. Louis, MO
Stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast, and WiFi. Our guests praise the helpful staff and the clean rooms in our ...
Renaissance St. Louis Airport Hotel
Hilton St. Louis Airport
Hilton St. Louis Airport
3.5 out of 5
10330 Natural Bridge Rd, St. Louis, MO
Stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast, and WiFi. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Hilton St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Book the perfect getaway to Mississippi River

With Hotwire, booking your next trip to United States of America is a breeze. When it comes to planning a show-stopping vacay, you’re the reigning champion of doing it on a dime. You love to plan exciting destination adventures while saving money on a budget.

Hotwire is here to help you plan a smooth sailing trip to Mississippi River while saving some major cash. Doubling up on vacation expenses like hotel and car rentals and fun-filled excursions can save you money—especially when you book one of Hotwire’s vacation packages.

If your trip to is spur-of-the-moment and you’re leaving soon, Hotwire can save you up to 60% off your rentals with Hotwire Hot Rate deals. Book with Hotwire to grab a stellar Mississippi River flight and hotel package for as low as $309.

Living it up in United States of America means getting there in style and staying in a hotel that matches your mood. Book one of Hotwire’s Mississippi River, United States of America vacation packages to enjoy the best of both worlds. Flight and hotel packages typically include roundtrip non-stop flights and multi-day hotel stays. Packages are priced per person and are perfect for flying solo or traveling with a group of friends or family. Conveniently choose from Hotwire’s inventory of hotels in Mississippi River for some of the best accommodations and flight deals.

FAQs about cheap Mississippi River packages:

How to get cheap vacation deals to Mississippi River?

Save up to 60% off vacation deals with Hotwire Hot Rates. Just plug in your general preferences and let Hotwire choose matching hotels for as low as $90.

How much are Mississippi River packages?

Vacation packages to Mississippi River vary in price. They are priced per person and include discounted hotel and flight costs. With Hotwire, you can score a vacation package for as low as $309.

How to find cheap car rentals near Mississippi River?

Hotwire partners with some of the most reliable car rental companies in United States of America to bring you the best car rental deals in Mississippi River for as low as . Select a rental from Hotwire’s extensive inventory of cars for every travel style. If you plan on bringing friends or family along, opt for a spacious SUV. If you’re visiting on business but still plan to make time for off-the-clock adventures, Hotwire offers sleek luxury and convertible rentals.

Is it safe to travel to Mississippi River now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Mississippi River right now?” When it’s time to book your vacation, check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.