See all properties

Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property

Choose dates to view prices

Photo gallery for Residence Inn Durham McPherson/Duke University Medical Cntr

Courtyard
Exterior
Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub) | 1 bedroom, in-room safe, desk, laptop workspace
Full-size fridge, microwave, stovetop, dishwasher
Lobby lounge

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Parking available
  • Bar
  • Kitchen
  • Housekeeping
$149
includes taxes & fees
Nov 23 - Nov 24

Explore the area

View in a map
1108 West Main Street, Durham, NC, 27701
  • Place, Brightleaf Square
    ‪3 min walk‬
  • Place, Duke University
    ‪3 min walk‬
  • Place, Durham Performing Arts Center
    ‪17 min walk‬
  • Airport, Raleigh, NC (RDU-Raleigh - Durham Intl.)
    ‪18 min drive‬

Room options

View all photos for Suite, 1 Bedroom

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

9.2 out of 10
Wonderful
(5 reviews)
  • 469 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Studio, 1 King Bed with Sofa bed, Non Smoking

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed, Non Smoking

8.8 out of 10
Excellent
(32 reviews)
  • 480 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 Queen Bed with Sofa bed, Non Smoking

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 Queen Bed with Sofa bed, Non Smoking

9.6 out of 10
Exceptional
(14 reviews)
  • 424 sq ft
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

8.8 out of 10
Excellent
(3 reviews)
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

  • 478 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

  • 479 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

  • 479 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

  • 426 sq ft
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

View all photos for Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub) | 1 bedroom, in-room safe, desk, laptop workspace

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

Similar properties

BBQ/picnic area
AC Hotel Durham
  • Pet friendly
  • Free WiFi
  • Restaurant
  • Air conditioning
4.6 out of 5, Wonderful, 598 reviews
AC Hotel Durham

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

3-star hotel in Downtown Durham
A 24-hour fitness center, a bar/lounge, and self parking are available at this smoke-free hotel. Free on-the-go breakfast, free WiFi in public areas, and a free area shuttle are also provided. Additionally, coffee/tea in a common area, a business center, and conference space are onsite. Housekeeping is available on request.
Residence Inn Durham McPherson/Duke University Medical Cntr offers 147 accommodations with safes and coffee/tea makers. Accommodations offer separate sitting areas and include dining tables. 32-inch Smart televisions come with premium cable channels, pay movies, and Netflix. Accommodations at this 3-star hotel have kitchens with full-sized refrigerators/freezers, stovetops, microwaves, and cookware/dishes/utensils. Bathrooms include shower/tub combinations, complimentary toiletries, and hair dryers.

This Durham hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and desk chairs, as well as phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include a 24-hour fitness center.

Children under 18 years old are not allowed in the swimming pool or fitness facility without adult supervision. Guests under 18 years old are not allowed in the fitness facility.

A bar/lounge is on site where guests can unwind with a drink. A complimentary breakfast is offered each morning. A computer station is located on site and wireless Internet access is complimentary.

A business center is on site at this 3-star property. Event facilities measuring 2530 square feet (235 square meters) include conference space. This business-friendly hotel also offers a 24-hour fitness center, a terrace, and coffee/tea in a common area. Parking is available onsite for a surcharge. A total renovation of this property was completed in April 2024.

Residence Inn Durham McPherson/Duke University Medical Cntr is a smoke-free property.

A complimentary on-the-go breakfast is served each morning between 7:00 AM and 9:00 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free area shuttle
  • Self parking on site (USD 15 per day)
  • Wheelchair-accessible parking available

Food and drink

  • Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
  • A bar/lounge
  • Coffee and tea in common areas

Things to do

  • 24-hour gym

Family friendly

  • Dining table
  • Free area shuttle
  • Grocery/convenience store
  • In-room full-sized refrigerator/freezer
  • In-room kitchen
  • In-room microwave
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Wedding services

Business services

  • 2,530 square feet of conference space
  • Business center
  • Computer station

Outdoors

  • Terrace

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 7 accessible parking spaces
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Hardwood flooring in room
  • Lever door handles
  • Thin carpet in room
  • Visual alarms in hallways
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk (34 inches high)
  • Wheelchair-accessible restaurant

More

  • 5 floors
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Built in 2015
  • Comprehensive recycling policy
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • No plastic drinking straws
  • Renovated entire property - April 2024
  • Smoking not allowed
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 32-inch smart TV with premium cable channels
  • Netflix
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dining table
  • Dishwasher
  • Full-sized refrigerator/freezer
  • Kitchen
  • Microwave
  • Stovetop

More

  • Air conditioning (climate-controlled)
  • Desk
  • Desk chair
  • Energy-saving switches in guestrooms
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Phone
  • Recycling
  • Safe
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Express check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100.00 per pet (varies based on length of stay)
Service animals are welcome, and are exempt from fees
2 total (up to 100 lbs per pet)
Restrictions apply; for more information contact the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Optional extras

  • Self parking fee: USD 15 per day
  • Pet fee: USD 100.00 per pet (varies based on length of stay)
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)

We should mention

Guests under 18 years old are not allowed in the fitness facility, and guests under 18 years old are only allowed in the swimming pool and fitness facility with adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn Durham McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 311 out of 456 reviews
Rating 8 - Good. 104 out of 456 reviews
Rating 6 - Okay. 26 out of 456 reviews
Rating 4 - Poor. 6 out of 456 reviews
Rating 2 - Terrible. 9 out of 456 reviews

9.4/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.4/10

Property conditions & facilities

9.0/10

Eco-friendliness

Reviews

10/10 Excellent

Derek

Liked: Cleanliness, staff & service, property conditions & facilities
Was very nice. The staff was very polite when we arrived.
Stayed 1 night in Aug 2025

10/10 Excellent

Heng Bao, Singapore

Stayed 22 nights in Jul 2025

10/10 Excellent

Melissa

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was amazing! Breakfast had so many options, quiche, waffles, fresh fruit, sausage, hard boiled eggs…. Room was very clean. Small market store in lobby. Lobby area with a tv and tons of seating. Nice workout room. But again, staff was incredible!
Stayed 8 nights in Jul 2025

10/10 Excellent

Ronnie A.

Liked: Cleanliness, staff & service, property conditions & facilities
We had an issue with the room but the district manager took care of it immediately. Excellent Team
Stayed 8 nights in Jul 2025

10/10 Excellent

Kaiqing, Singapore

Liked: Cleanliness, staff & service, property conditions & facilities
All good as expected
Stayed 14 nights in Jul 2025

8/10 Good

Heman, Eagle River

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
Laura and Tiffany were extremely helpful and accommodating. The whole staff was very friendly and welcoming!
Stayed 9 nights in Jul 2025

10/10 Excellent

Talal

Stayed 2 nights in Jun 2025

8/10 Good

Lourdes Dolores

Liked: Cleanliness, property conditions & facilities, room comfort

Wasteful shower design

The room was clean and comfortable and the gym was good. However, I gave the hotel 3 stars because the shower lets out so much water that it is actually wasting water. There's no door for the shower, so when you bathe, the water streams out of the shower and onto the bathroom floor. So much water streams out that I had to place the bathmat 12 inches away from the shower entrance so that it wouldn't get wet.
Stayed 10 nights in Jun 2025

8/10 Good

PRAVEEN

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good place to stay ...convenient to walk to Duke

The check in was super nice. The air conditioner was making a lot of noise - a racket. We had to complain multiple times. But they did respond 🙄 after the third vociferous complaint and replaced compressor. Friendly maintainence team , Barry the maintainence executive brought in a lot of smiles with his attitude.
Stayed 14 nights in Jun 2025

10/10 Excellent

LaMeesha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.
Stayed 8 nights in Jun 2025

10/10 Excellent

Timmy

Liked: Cleanliness, amenities, property conditions & facilities
It was very clean and the staff was excellent. The stay was really good. The attendant was great at checking.
Stayed 1 night in Jun 2025

10/10 Excellent

Daneen

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in May 2025

10/10 Excellent

David

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We love staying here when we come to visit our family. Every stay has been wonderful. The room is very comfortable. We love the gym and the breakfasts. Having a nice laundry area on the premises is also a huge plus. The best part is the fantastic staff-everyone is so nice and helpful. Thank you for always making our trips memorable.
Stayed 7 nights in May 2025

6/10 Okay

Tian

Traveled with family
Disliked: Staff & service, amenities
It smelled musky and like urine in our room and much of the facility just smelled like cleaning supplies. The wifi wasn’t great in the room. The location is decently close to Duke, but the immediate area is at a street intersection right by a gas station. There was plenty of parking for pay by mobile 15$.
Stayed 1 night in May 2025

10/10 Excellent

douglas

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in May 2025

8/10 Good

Robert

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Shoutout to Tiffany/Stephanie? on front desk duty - she greeted us with a warm welcome & useful information!
Stayed 1 night in May 2025

10/10 Excellent

Reed

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The place to stay if you have business at Duke. Housekeeping is hit-or-miss, but that's par for the course for an extended-stay hotel.
Stayed 6 nights in Apr 2025

10/10 Excellent

Andrea

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Apr 2025

10/10 Excellent

Verified traveler

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great value, good location, decent breakfast

Clean, walking distance to gas stations and restaurants.,, decent breakfast in the morning that was free so can't complain... free hot coffee all day... spacious and well-decorated rooms with good cable and smart tvs. All around, great value for the price
Stayed 2 nights in Jan 2025

10/10 Excellent

chantal

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Hong

Liked: Cleanliness, staff & service, property conditions & facilities
Nice staff, very helpful. Close to Duke University, great place to stay.
Stayed 6 nights in Jan 2025

10/10 Excellent

Kenneth, Virginia Beach

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Jan 2025

8/10 Good

Minor, Greenville

Liked: Cleanliness, staff & service
An excellent place to stay!
Stayed 1 night in Feb 2025

8/10 Good

Irina

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Peter

Stayed 1 night in Jan 2025