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Santiago Island Vacation Packages

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One of the highlights of my trip to the Galapagos was snorkeling with Galapagos penguins off of Bartolome Island. Galapagos Penguins are the only penguin bread found north of the equator. #lifeatexpedia

Photo by Sarah Mack

Santiago Island
Galápagos
Ecuador
South America
Hotwire.com

Santiago Island Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Hotel el descanso del Guia

3.5 out of 5

Price was $505, price is now $370 per person

$370

per person

Dec 8 - Dec 11

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Stay at this 3.5-star family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions Las Ninfas Lagoon and Fishing Piers are located nearby.

BAY VIEW HOUSE

3.5 out of 5

Price was $769, price is now $496 per person

$496

per person

Dec 8 - Dec 11

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Stay at this 3.5-star spa guesthouse in Puerto Ayora. Enjoy free WiFi, a full-service spa, and daily housekeeping. Popular attractions Gus Angermeyer Ferry Terminal and Malecon are located nearby.

Hostal España

3 out of 5

Save 100% on your flight

Price was $1,246, price is now $832 per person

$832

per person

Dec 8 - Dec 11

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Stay at this 3-star business-friendly hostal in Puerto Ayora. Enjoy free breakfast, free parking, and a rooftop terrace. Popular attractions Gus Angermeyer Ferry Terminal and Fishing Piers are located nearby.

Angermeyer Waterfront Inn

3.5 out of 5

Price was $859, price is now $618 per person

$618

per person

Jan 12 - Jan 15

found 1 day ago

Roundtrip non-stop flight included

Quito (UIO) to Isla Baltra (GPS)

Stay at this 3.5-star hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a marina. Our guests praise the helpful staff in our reviews. Popular attractions Playa de los Alemanes and Malecon are located nearby.

La Casa de Marita

3 out of 5

Price was $957, price is now $719 per person

$719

per person

Dec 9 - Dec 13

found 10 hours ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Stay at this 3-star beach hotel in Puerto Villamil. Enjoy free breakfast, free WiFi, and free parking. Popular attractions El Embarcadero Pier and Concha de Perla Nature Park are located nearby.

Hotel Albemarle Galapagos Beachfront

3.5 out of 5

Price was $666, price is now $514 per person

$514

per person

Dec 9 - Dec 13

found 10 hours ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Stay at this 3.5-star beach hotel in Puerto Villamil. Enjoy free WiFi, a beach locale, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions El Embarcadero Pier and Concha de Perla Nature Park are located nearby.

Galapagos Sea Star

2 out of 5

Save 100% on your flight

Price was $2,928, price is now $2,277 per person

$2,277

per person

Jan 12 - Jan 15

found 1 day ago

Roundtrip non-stop flight included

Quito (UIO) to Isla Baltra (GPS)

Stay at this cruise ship in Puerto Ayora. Enjoy free breakfast, WiFi (surcharge), and daily housekeeping. Popular attractions Fishing Piers and Gus Angermeyer Ferry Terminal are located nearby.

Natura Gardens Galápagos Hotel

3 out of 5

Price was $508, price is now $397 per person

$397

per person

Dec 8 - Dec 11

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Stay at this 3-star hotel in Bella Vista. Enjoy free breakfast, onsite spa services, and daily housekeeping. Popular attractions Charles Darwin Research Station and Fishing Piers are located nearby.