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Selected fares from Des Moines to San Francisco

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Route Information for Flights from Des Moines to San Francisco

Origin Airport IATA Code DSM
Destination Airport IATA Code SFO
Flight Price $188
Distance 2,474 km

Des Moines (DSM) to San Francisco (SJC)

Work or play? Either way, you're going to want a great deal on a flight to San Francisco. Because when you eventually land, you have a city that is waiting to be explored, and that extra cash in your pocket can take your trip from "meh" to amazing. You're in the right spot to score an awesome deal on your next flight from Des Moines. Whether you are an expert at navigating the friendly skies or only have a few trips under your wing, read below to score the best deal on your next flight.

How can you get a great rate on tickets from Des Moines to San Francisco?

We've been in the game a long time, which means getting that great deal on a San Francisco flight is easy-peasy. You'll make spending less look so very good with a few simple steps.

What is the best day of the week to book a flight?

With the right attitude and flexibility, you can fly for less. Below are the cheapest days to fly:

  • Tuesday and Wednesday—You know how most stores are not crowded midweek? Same thing here. Most people opt to depart at the beginning or end of the week.
  • Thursday and Saturday—Get a head start on that Friday crowd. This also works on your return flight. Shorten your vacay by a day and increase your savings.
  • Monday through Thursday—If you're flying internationally, deals are often available when departing these days.

Can staying the weekend get me a cheaper ticket?

If you stay through the weekend, generally that return ticket to DSM can be cheaper since you'll be leaving earlier in the week. All those business travelers have less elastic schedules, so that means savings for you. We are all for that!

Can you save while traveling during the off-peak season?

Off-peak and shoulder seasons are when most vacationers aren't flying to certain locations. So when it's cold, most people head off to warmer climates like the Caribbean, Mexico, Hawaii, etc., just like our feathered friends. But during the summer months, you'll find that Europe gets busy. You may not get the ideal weather, but you'll generally get better rates and be there when it is not flocked by out of towners.

If the price is right, pick it!

You're not the only one waiting a great deal on a flight from Des Moines to San Francisco. You may lose your chance to dial in the time and the flight you wanted.

What is the Hotwire Hot Rate?

If you prioritize cost over everything else, then the Hotwire Hot Rate is for you. You'll get a great deal on a ticket to San Francisco from Des Moines. You won't know the time and airline until after you book, but if you are not on a set schedule, you can save big on your flight.

Book your flight today

Use our guide before you book your upcoming flight from Des Moines to San Francisco. You may have enough money back in your hand to add something that makes this vacay extra awesome ... or you can pocket the savings and put it toward your next flight out of Des Moines.

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^Savings based on all package bookings with Flight + Hotel made on Hotwire.com from January 1, 2018 to December 31, 2018 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.