Search for Cheap Deals on
4 Star Hotels in Brindisi

Check Last Minute Brindisi Hotel Deals

Tonight Nov 29 - Nov 30Next weekend Dec 5 - Dec 7

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured 4 Star Brindisi Hotels

Grand Hotel di Lecce
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Perrino Hospital
Stay at this hotel in Lecce. Enjoy free breakfast, free WiFi, and an outdoor pool. Popular attractions Railway Museum of Puglia and Sigismondo Castromediano ...
Opens in a new windowGrand Hotel di Lecce
Grand Hotel Tiziano e dei Congressi
4 out of 5
Fully refundableReserve now, pay when you stay
  • 59 min drive from Perrino Hospital
Book a stay at this spa hotel in Lecce. Enjoy free breakfast, free WiFi, and free parking. Popular attractions City Walls and Chiesa dei Santi Nicolo e Cataldo ...
Opens in a new windowGrand Hotel Tiziano e dei Congressi
Hotel Orientale
4 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from Perrino Hospital
Book a stay at this business-friendly hotel in Brindisi. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. ...
Opens in a new windowHotel Orientale
Save an average of 15% on thousands of hotels when you're signed in
Palazzo Virgilio
4 out of 5
Fully refundableReserve now, pay when you stay
  • 4 min drive from Perrino Hospital
Book a stay at this business-friendly hotel in Brindisi. Enjoy free WiFi, 24-hour room service, and parking (surcharge). Our guests praise the helpful staff ...
Opens in a new windowPalazzo Virgilio
Hotel Executive Inn
4 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from Perrino Hospital
Stay at this hotel in Brindisi. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Piazza ...
Opens in a new windowHotel Executive Inn
Grande Albergo Internazionale
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from Perrino Hospital
Book a stay at this business-friendly hotel in Brindisi. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. ...
Opens in a new windowGrande Albergo Internazionale
Mercure Hotel President Lecce
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Perrino Hospital
Book a stay at this business-friendly hotel in Lecce. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Chinese Missionary Museum ...
Opens in a new windowMercure Hotel President Lecce
Pollicastro Boutique Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Perrino Hospital
Book a stay at this boutique hotel in Lecce. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
Opens in a new windowPollicastro Boutique Hotel
Hotel Delle Palme
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Perrino Hospital
Book a stay at this business-friendly hotel in Lecce. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions Torre del Parco and ...
Opens in a new windowHotel Delle Palme
8Piuhotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 58 min drive from Perrino Hospital
Stay at this hotel in Lecce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Chiesa ...
Opens in a new window8Piuhotel
Best Western Plus Leone di Messapia Hotel & Conference
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Perrino Hospital
Book a stay at this family-friendly hotel in Lecce. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Torre del Parco and Casa Museo ...
Opens in a new windowBest Western Plus Leone di Messapia Hotel & Conference
Hotel Monte Sarago
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Perrino Hospital
Book a stay at this spa hotel in Ostuni. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Opens in a new windowHotel Monte Sarago
Don't see what you're looking for?
See all available properties in Brindisi
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in Brindisi

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Brindisi for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Brindisi as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Brindisi 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Brindisi starting at $103 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Brindisi 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.