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Greenville

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Greenville Flights as Low as $88

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Spirit Airlines
Thu, Jun 19 - Fri, Jun 20
DTW
Detroit Metropolitan Wayne County
STL
Lambert-St. Louis Intl.
$88 Roundtrip, found 5 days ago
$88
Roundtrip
found 5 days ago
Select Spirit Airlines flight, departing Thu, Jun 19 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Fri, Jun 20, priced at $88 found 5 days ago
Frontier Airlines
Sat, Jul 26 - Sat, Aug 2
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$130 Roundtrip, found 1 day ago
$130
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Jul 26 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Aug 2, priced at $130 found 1 day ago
Frontier Airlines
Sat, Jul 19 - Sun, Jul 20
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$140 Roundtrip, found 2 days ago
$140
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sat, Jul 19 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, Jul 20, priced at $140 found 2 days ago
Spirit Airlines
Mon, Jun 16 - Mon, Jun 16
DTW
Detroit Metropolitan Wayne County
STL
Lambert-St. Louis Intl.
$146 Roundtrip, found 5 days ago
$146
Roundtrip
found 5 days ago
Select Spirit Airlines flight, departing Mon, Jun 16 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Mon, Jun 16, priced at $146 found 5 days ago
Spirit Airlines
Mon, Jun 16 - Thu, Jun 19
DTW
Detroit Metropolitan Wayne County
STL
Lambert-St. Louis Intl.
$151 Roundtrip, found 3 days ago
$151
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Mon, Jun 16 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Thu, Jun 19, priced at $151 found 3 days ago
Delta
Thu, Jun 12 - Sun, Jun 15
DTW
Detroit Metropolitan Wayne County
STL
Lambert-St. Louis Intl.
$161 Roundtrip, found 4 days ago
$161
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Jun 12 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Sun, Jun 15, priced at $161 found 4 days ago
Delta
Sat, Jul 26 - Sat, Aug 2
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$164 Roundtrip, found 1 day ago
$164
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jul 26 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Aug 2, priced at $164 found 1 day ago
American Airlines
Thu, Jun 12 - Sun, Jun 15
DTW
Detroit Metropolitan Wayne County
STL
Lambert-St. Louis Intl.
$167 Roundtrip, found 4 days ago
$167
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jun 12 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Sun, Jun 15, priced at $167 found 4 days ago
American Airlines
Thu, Jul 17 - Sun, Jul 20
DTW
Detroit Metropolitan Wayne County
STL
Lambert-St. Louis Intl.
$170 Roundtrip, found 1 day ago
$170
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jul 17 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Sun, Jul 20, priced at $170 found 1 day ago
American Airlines
Sat, Jul 26 - Sat, Aug 2
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$174 Roundtrip, found 1 day ago
$174
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jul 26 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Aug 2, priced at $174 found 1 day ago
Delta
Sun, Jun 15 - Sun, Jun 15
DTW
Detroit Metropolitan Wayne County
STL
Lambert-St. Louis Intl.
$178 Roundtrip, found 5 days ago
$178
Roundtrip
found 5 days ago
Select Delta flight, departing Sun, Jun 15 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Sun, Jun 15, priced at $178 found 5 days ago
Spirit Airlines
Mon, Jun 16 - Tue, Jul 15
FLL
Fort Lauderdale - Hollywood Intl.
STL
Lambert-St. Louis Intl.
$189 Roundtrip, found 4 hours ago
$189
Roundtrip
found 4 hours ago
Select Spirit Airlines flight, departing Mon, Jun 16 from Fort Lauderdale - Hollywood Intl. to Lambert-St. Louis Intl., returning Tue, Jul 15, priced at $189 found 4 hours ago
American Airlines
Tue, Jun 17 - Wed, Jun 18
DTW
Detroit Metropolitan Wayne County
STL
Lambert-St. Louis Intl.
$199 Roundtrip, found 4 hours ago
$199
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Jun 17 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Wed, Jun 18, priced at $199 found 4 hours ago
United
Tue, Jun 17 - Wed, Jun 18
DTW
Detroit Metropolitan Wayne County
STL
Lambert-St. Louis Intl.
$237 Roundtrip, found 4 hours ago
$237
Roundtrip
found 4 hours ago
Select United flight, departing Tue, Jun 17 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Wed, Jun 18, priced at $237 found 4 hours ago
American Airlines
Tue, Jun 17 - Wed, Jul 16
PBI
Palm Beach Intl.
STL
Lambert-St. Louis Intl.
$316 Roundtrip, found 4 hours ago
$316
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Jun 17 from Palm Beach Intl. to Lambert-St. Louis Intl., returning Wed, Jul 16, priced at $316 found 4 hours ago
American Airlines
Mon, Jul 28 - Wed, Aug 6
PBI
Palm Beach Intl.
SPI
Abraham Lincoln Capital
$512 Roundtrip, found 1 day ago
$512
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jul 28 from Palm Beach Intl. to Abraham Lincoln Capital, returning Wed, Aug 6, priced at $512 found 1 day ago

Cheap Flights to Greenville

Fall in love at first flight with your vacation to Greenville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Greenville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Greenville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Greenville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Greenville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the BLV airport.

What is the cheapest month to fly to Greenville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Greenville are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Greenville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Greenville.

What airport is best to fly into Greenville?

When you’re planning your trip to Greenville, convenience is the name of the game. Luckily, Greenville Lambert-St. Louis Intl. Airport is nearby so you can deplane and get going on checking off everything on your Greenville must-do list.

How much are flights to Greenville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Greenville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $88, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Greenville?

The trick to saving a stack of cash on your flight to Greenville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $88 right now, why wait?

Greenville Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$88

Last Minute Hotel Deals in Greenville

Super 8 by Wyndham Greenville
Super 8 by Wyndham Greenville
2 out of 5
1700 State Route 127, Greenville, IL
The price is $74 per night from Apr 21 to Apr 22
$74
includes taxes & fees
Apr 21 - Apr 22
Book a stay at this business-friendly motel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (690 reviews)
"Good overall."

Reviewed on Apr 9, 2025

Super 8 by Wyndham Greenville
Comfort Inn & Suites Greenville I-70
Comfort Inn & Suites Greenville I-70
2.5 out of 5
2265 S. State Route 127, Greenville, IL
The price is $101 per night from Apr 30 to May 1
$101
includes taxes & fees
Apr 30 - May 1
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (363 reviews)
"Staff was great. There was glass in the pool. My child cut their toe and another cut their foot. Very disappointing. Rooms are basic and need updating."

Reviewed on Mar 2, 2025

Comfort Inn & Suites Greenville I-70
SureStay Hotel by Best Western Greenville
SureStay Hotel by Best Western Greenville
2.5 out of 5
1731 S State Route 127, Greenville, IL
The price is $64 per night from Apr 20 to Apr 21
$64
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff ...
7.6/10 Good! (509 reviews)
"Front desk person was super nice and helped us get situated with ease."

Reviewed on Apr 10, 2025

SureStay Hotel by Best Western Greenville
Budget Inn- Greenville
Budget Inn- Greenville
2 out of 5
1525 South State Rt 127, Greenville, IL
The price is $55 per night from Apr 16 to Apr 17
$55
includes taxes & fees
Apr 16 - Apr 17
Stay at this motel in Greenville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Greenville Country Club and Patriot's Park are ...
6.2/10 (142 reviews)
"good value, nice room"

Reviewed on Mar 11, 2025

Budget Inn- Greenville
Quality Inn & Suites Vandalia near I-70 and Hwy 51
Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 out of 5
1920 Kennedy Boulevard, Vandalia, IL
The price is $60 per night from May 4 to May 5
$60
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Vandalia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,002 reviews)
"I moved from NV to Indiana and had 4 night stays with my journey along with 2 dogs and 3 cats....out of the 4 hotels this was the best place to stay....thank you for everything and making my final stay perfect....like finding a pot of gold at the end of a rainbow😁"

Reviewed on Mar 30, 2025

Quality Inn & Suites Vandalia near I-70 and Hwy 51
Holiday Inn Express & Suites Vandalia by IHG
Holiday Inn Express & Suites Vandalia by IHG
2.5 out of 5
21 Mattes Ave, Vandalia, IL
The price is $126 per night from May 4 to May 5
$126
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Vandalia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (688 reviews)
"Manager was outstanding. Clean rooms"

Reviewed on Apr 4, 2025

Holiday Inn Express & Suites Vandalia by IHG
Baymont by Wyndham Litchfield
Baymont by Wyndham Litchfield
2.5 out of 5
1405 W Hudson Dr, Litchfield, IL
The price is $99 per night from Apr 16 to Apr 17
$99
includes taxes & fees
Apr 16 - Apr 17
Book a stay at this business-friendly hotel in Litchfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,003 reviews)
"I forgot an item in our room when we left. I called the hotel and they went to the room and found the item, and kept it at the front desk until I could return for it. Manager went above and beyond for me. Wonderful. Thank you."

Reviewed on Apr 3, 2025

Baymont by Wyndham Litchfield
Best Western Plus Centralia Hotel & Suites
Best Western Plus Centralia Hotel & Suites
2.5 out of 5
8145 Jolliff Bridge Rd, Centralia, IL
The price is $151 per night from Apr 20 to Apr 21
$151
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Centralia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (522 reviews)
"Very nice motel."

Reviewed on Apr 9, 2025

Best Western Plus Centralia Hotel & Suites
See all 54 properties in Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.