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Greenville

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Greenville Flights as Low as $177

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Sat, Sep 20 - Wed, Sep 24
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$177 Roundtrip, found 5 days ago
$177
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Sep 20 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Wed, Sep 24, priced at $177 found 5 days ago
Delta
Sat, Sep 20 - Fri, Sep 26
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$218 Roundtrip, found 5 days ago
$218
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Sep 20 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Fri, Sep 26, priced at $218 found 5 days ago
American Airlines
Thu, Jul 24 - Thu, Jul 31
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$220 Roundtrip, found 6 days ago
$220
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jul 24 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Thu, Jul 31, priced at $220 found 6 days ago
Delta
Thu, Jul 24 - Thu, Jul 31
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$220 Roundtrip, found 6 days ago
$220
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Jul 24 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Thu, Jul 31, priced at $220 found 6 days ago
Delta
Thu, Jul 24 - Thu, Jul 31
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$225 Roundtrip, found 6 days ago
$225
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Jul 24 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Thu, Jul 31, priced at $225 found 6 days ago
American Airlines
Thu, Jul 24 - Thu, Jul 31
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$226 Roundtrip, found 6 days ago
$226
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jul 24 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Thu, Jul 31, priced at $226 found 6 days ago
American Airlines
Tue, Sep 23 - Sun, Sep 28
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$236 Roundtrip, found 5 days ago
$236
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Sep 23 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Sun, Sep 28, priced at $236 found 5 days ago
American Airlines
Fri, Sep 19 - Sun, Sep 28
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$243 Roundtrip, found 5 days ago
$243
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Sep 19 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Sun, Sep 28, priced at $243 found 5 days ago
American Airlines
Thu, Jul 24 - Thu, Jul 31
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$256 Roundtrip, found 6 days ago
$256
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jul 24 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Thu, Jul 31, priced at $256 found 6 days ago
American Airlines
Thu, Jul 24 - Tue, Jul 29
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$261 Roundtrip, found 6 days ago
$261
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jul 24 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Tue, Jul 29, priced at $261 found 6 days ago
American Airlines
Thu, Jul 24 - Tue, Jul 29
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$261 Roundtrip, found 6 days ago
$261
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jul 24 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Tue, Jul 29, priced at $261 found 6 days ago
Delta
Thu, Jul 24 - Thu, Jul 31
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$262 Roundtrip, found 6 days ago
$262
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Jul 24 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Thu, Jul 31, priced at $262 found 6 days ago
American Airlines
Thu, Jul 24 - Thu, Jul 31
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$271 Roundtrip, found 6 days ago
$271
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jul 24 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Thu, Jul 31, priced at $271 found 6 days ago
Delta
Fri, Jul 25 - Thu, Jul 31
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$271 Roundtrip, found 6 days ago
$271
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Jul 25 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Thu, Jul 31, priced at $271 found 6 days ago
American Airlines
Sat, Aug 9 - Tue, Aug 19
JAX
Jacksonville Intl.
MWA
Williamson County Regional
$308 Roundtrip, found 5 days ago
$308
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Aug 9 from Jacksonville Intl. to Williamson County Regional, returning Tue, Aug 19, priced at $308 found 5 days ago
United
Thu, Jul 24 - Thu, Jul 31
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$343 Roundtrip, found 6 days ago
$343
Roundtrip
found 6 days ago
Select United flight, departing Thu, Jul 24 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Thu, Jul 31, priced at $343 found 6 days ago

Cheap Flights to Greenville

Fall in love at first flight with your vacation to Greenville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Greenville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Greenville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Greenville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Greenville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the BLV airport.

What is the cheapest month to fly to Greenville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Greenville are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Greenville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Greenville.

What airport is best to fly into Greenville?

When you’re planning your trip to Greenville, convenience is the name of the game. Luckily, Greenville Lambert-St. Louis Intl. Airport is nearby so you can deplane and get going on checking off everything on your Greenville must-do list.

How much are flights to Greenville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Greenville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $177, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Greenville?

The trick to saving a stack of cash on your flight to Greenville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $177 right now, why wait?

Greenville Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$157

Last Minute Hotel Deals in Greenville

Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville

2 out of 5
1700 State Route 127, Greenville, IL
Book a stay at this business-friendly motel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (715 reviews)
"This property is fine for the price point. The rooms are a bit outdated but typically clean. They do however have smoking areas right outside both the front and back door which can be a bit annoying at times otherwise for a night or two it’s worth the price."

Reviewed on Jul 11, 2025

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Super 8 by Wyndham Greenville
SureStay Hotel by Best Western Greenville

SureStay Hotel by Best Western Greenville

2.5 out of 5
1731 S State Route 127, Greenville, IL
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff ...
7.4/10 Good! (538 reviews)
"Clean property from the parking lot, to the lobby and halls to the room. Easy check in with friendly staff. Quiet, safe area with no problems at a great price. I have paid a lot more for a lot less."

Reviewed on Jul 9, 2025

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SureStay Hotel by Best Western Greenville
Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70

2.5 out of 5
2265 S. State Route 127, Greenville, IL
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (385 reviews)
"Staff was great. Check in was easy and everything was very clean (lobby, dining area, pool area, room, etc...). I plan on coming back next year, and this will be where I will stay."

Reviewed on Jun 25, 2025

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Comfort Inn & Suites Greenville I-70
Budget Inn- Greenville

Budget Inn- Greenville

2 out of 5
1525 South State Rt 127, Greenville, IL
Stay at this motel in Greenville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Greenville Country Club and Patriot's Park are ...
6.6/10 (154 reviews)
Great stay
"Great affordable place will definitely stsy again"

Reviewed on Jul 14, 2025

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Budget Inn- Greenville
Baymont by Wyndham Litchfield

Baymont by Wyndham Litchfield

2.5 out of 5
1405 W Hudson Dr, Litchfield, IL
Book a stay at this business-friendly hotel in Litchfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,009 reviews)
"Clean is my biggest thing and we definitely got that."

Reviewed on Jul 11, 2025

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Baymont by Wyndham Litchfield
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51

2.5 out of 5
1920 Kennedy Boulevard, Vandalia, IL
Book a stay at this business-friendly hotel in Vandalia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,007 reviews)
"Everyone was friendly and the breakfast had a great variety. Very clean rooms."

Reviewed on Jul 9, 2025

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Quality Inn & Suites Vandalia near I-70 and Hwy 51
Seasons Inn & Suites Highland

Seasons Inn & Suites Highland

2.5 out of 5
20 Central Blvd, Highland, IL
Book a stay at this business-friendly hotel in Highland. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (589 reviews)
"Very serviceable, clean, spacious"

Reviewed on Jul 13, 2025

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Seasons Inn & Suites Highland
Super 8 by Wyndham Staunton

Super 8 by Wyndham Staunton

2 out of 5
1527 Herman Rd, Staunton, IL
Book a stay at this business-friendly hotel in Staunton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (725 reviews)
"Clean and comfortable, with very nice and attentive staff."

Reviewed on Jul 8, 2025

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Super 8 by Wyndham Staunton
See all 56 properties in Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.