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Guthrie Center

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Guthrie Center Flights as Low as $221

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

United
Tue, May 13 - Wed, May 14
ORD
O'Hare Intl.
OMA
Eppley Field
$221 Roundtrip, found 13 hours ago
$221
Roundtrip
found 13 hours ago
Select United flight, departing Tue, May 13 from O'Hare Intl. to Eppley Field, returning Wed, May 14, priced at $221 found 13 hours ago
American Airlines
Tue, May 13 - Wed, May 14
ORD
O'Hare Intl.
OMA
Eppley Field
$221 Roundtrip, found 13 hours ago
$221
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, May 13 from O'Hare Intl. to Eppley Field, returning Wed, May 14, priced at $221 found 13 hours ago
American Airlines
Tue, May 13 - Wed, May 14
ORD
O'Hare Intl.
OMA
Eppley Field
$223 Roundtrip, found 13 hours ago
$223
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, May 13 from O'Hare Intl. to Eppley Field, returning Wed, May 14, priced at $223 found 13 hours ago
Delta
Tue, May 13 - Wed, May 14
ORD
O'Hare Intl.
OMA
Eppley Field
$231 Roundtrip, found 13 hours ago
$231
Roundtrip
found 13 hours ago
Select Delta flight, departing Tue, May 13 from O'Hare Intl. to Eppley Field, returning Wed, May 14, priced at $231 found 13 hours ago
American Airlines
Fri, May 30 - Wed, Jun 4
ORD
O'Hare Intl.
OMA
Eppley Field
$231 Roundtrip, found 2 days ago
$231
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, May 30 from O'Hare Intl. to Eppley Field, returning Wed, Jun 4, priced at $231 found 2 days ago
Bargain Flight
Fri, Sep 5 - Mon, Sep 8
ATL
Hartsfield-Jackson Atlanta Intl.
OMA
Eppley Field
$233 Roundtrip, found 1 day ago
$233
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Fri, Sep 5 from Hartsfield-Jackson Atlanta Intl. to Eppley Field, returning Mon, Sep 8, priced at $233 found 1 day ago
Delta
Tue, May 13 - Wed, May 14
ORD
O'Hare Intl.
OMA
Eppley Field
$233 Roundtrip, found 13 hours ago
$233
Roundtrip
found 13 hours ago
Select Delta flight, departing Tue, May 13 from O'Hare Intl. to Eppley Field, returning Wed, May 14, priced at $233 found 13 hours ago
United
Tue, May 13 - Wed, May 14
ORD
O'Hare Intl.
OMA
Eppley Field
$234 Roundtrip, found 13 hours ago
$234
Roundtrip
found 13 hours ago
Select United flight, departing Tue, May 13 from O'Hare Intl. to Eppley Field, returning Wed, May 14, priced at $234 found 13 hours ago
Delta
Sun, May 11 - Tue, May 13
ORD
O'Hare Intl.
OMA
Eppley Field
$237 Roundtrip, found 13 hours ago
$237
Roundtrip
found 13 hours ago
Select Delta flight, departing Sun, May 11 from O'Hare Intl. to Eppley Field, returning Tue, May 13, priced at $237 found 13 hours ago
Frontier Airlines
Sun, May 18 - Wed, May 21
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$238 Roundtrip, found 1 day ago
$238
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, May 18 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Wed, May 21, priced at $238 found 1 day ago
United
Fri, May 30 - Wed, Jun 4
ORD
O'Hare Intl.
OMA
Eppley Field
$240 Roundtrip, found 2 days ago
$240
Roundtrip
found 2 days ago
Select United flight, departing Fri, May 30 from O'Hare Intl. to Eppley Field, returning Wed, Jun 4, priced at $240 found 2 days ago
Delta
Sat, May 10 - Sat, May 10
ORD
O'Hare Intl.
OMA
Eppley Field
$240 Roundtrip, found 13 hours ago
$240
Roundtrip
found 13 hours ago
Select Delta flight, departing Sat, May 10 from O'Hare Intl. to Eppley Field, returning Sat, May 10, priced at $240 found 13 hours ago
Bargain Flight
Wed, Jul 2 - Wed, Jul 9
SJC
Norman Y. Mineta San Jose Intl.
OMA
Eppley Field
$257 Roundtrip, found 11 hours ago
$257
Roundtrip
found 11 hours ago
Select Bargain Flight flight, departing Wed, Jul 2 from Norman Y. Mineta San Jose Intl. to Eppley Field, returning Wed, Jul 9, priced at $257 found 11 hours ago
Bargain Flight
Mon, Apr 28 - Fri, May 2
STL
Lambert-St. Louis Intl.
OMA
Eppley Field
$262 Roundtrip, found 11 hours ago
$262
Roundtrip
found 11 hours ago
Select Bargain Flight flight, departing Mon, Apr 28 from Lambert-St. Louis Intl. to Eppley Field, returning Fri, May 2, priced at $262 found 11 hours ago
Delta
Sat, Jul 12 - Wed, Jul 23
BOS
Logan Intl.
OMA
Eppley Field
$287 Roundtrip, found 11 hours ago
$287
Roundtrip
found 11 hours ago
Select Delta flight, departing Sat, Jul 12 from Logan Intl. to Eppley Field, returning Wed, Jul 23, priced at $287 found 11 hours ago
Alaska Airlines
Wed, Jul 2 - Wed, Jul 9
SJC
Norman Y. Mineta San Jose Intl.
OMA
Eppley Field
$681 Roundtrip, found 11 hours ago
$681
Roundtrip
found 11 hours ago
Select Alaska Airlines flight, departing Wed, Jul 2 from Norman Y. Mineta San Jose Intl. to Eppley Field, returning Wed, Jul 9, priced at $681 found 11 hours ago

Cheap Flights to Guthrie Center

Fall in love at first flight with your vacation to Guthrie Center by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Guthrie Center on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Guthrie Center, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Guthrie Center

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Guthrie Center with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the null airport.

What is the cheapest month to fly to Guthrie Center?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Guthrie Center are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Guthrie Center?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Guthrie Center.

What airport is best to fly into Guthrie Center?

When you’re planning your trip to Guthrie Center, convenience is the name of the game. Luckily, Guthrie Center Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Guthrie Center must-do list.

How much are flights to Guthrie Center?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Guthrie Center on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $221, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Guthrie Center?

The trick to saving a stack of cash on your flight to Guthrie Center? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $221 right now, why wait?

Guthrie Center Flight Information
Destination airport
Eppley Field
Destination airport IATA code
OMA
Roundtrip price
$220

Last Minute Hotel Deals in Guthrie Center

Midway Motel
Midway Motel
2.5 out of 5
2301 State St, Guthrie Center, IA
The price is $110 per night from Apr 19 to Apr 20
$110
includes taxes & fees
Apr 19 - Apr 20
Book a stay at this golf motel in Guthrie Center. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Lake Panorama and Sheeder Prairie ...
9.4/10 Exceptional! (21 reviews)
"This is an awesome place to stay. Very clean and safe. The beds are very comfortable. Everything was excellent!!"

Reviewed on Mar 9, 2025

Midway Motel
AmericInn by Wyndham Stuart
AmericInn by Wyndham Stuart
2.5 out of 5
420 SW 8th St, Stuart, IA
The price is $107 per night from Apr 27 to Apr 28
$107
includes taxes & fees
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Stuart. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (459 reviews)
Clean and comfortable.
"Very clean and comfortable. Just a pass through stay. Town has much more to offer than expected."

Reviewed on Apr 7, 2025

AmericInn by Wyndham Stuart
Cobblestone Hotel & Suites - Jefferson
Cobblestone Hotel & Suites - Jefferson
3 out of 5
771 Wild Rose Lane, Jefferson, IA
The price is $134 per night from Apr 20 to Apr 21
$134
includes taxes & fees
Apr 20 - Apr 21
Stay at this 3-star business-friendly hotel in Jefferson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
9/10 Wonderful! (327 reviews)
"Clean rooms-"

Reviewed on Apr 14, 2025

Cobblestone Hotel & Suites - Jefferson
Motel 6 Stuart, IA
Motel 6 Stuart, IA
2 out of 5
203 SE 7th Street, Stuart, IA
The price is $73 per night from Apr 20 to Apr 21
$73
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly motel in Stuart. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (694 reviews)
"We had a clean room for a good nights sleep."

Reviewed on Apr 15, 2025

Motel 6 Stuart, IA
Super 8 by Wyndham Jefferson
Super 8 by Wyndham Jefferson
2.5 out of 5
207 West Gallup Road, Junction of, Highway 30 and Highway 4, Jefferson, IA
The price is $79 per night from May 4 to May 5
$79
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Jefferson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Mahanay Memorial Carillon Tower ...
7.4/10 Good! (194 reviews)
Night away due to storm
"Nice stay for the night"

Reviewed on Mar 10, 2025

Super 8 by Wyndham Jefferson
Days Inn by Wyndham Atlantic
Days Inn by Wyndham Atlantic
2 out of 5
64968 Boston Road, Atlantic, IA
The price is $71 per night from Apr 25 to Apr 26
$71
includes taxes & fees
Apr 25 - Apr 26
Book a stay at this business-friendly motel in Atlantic. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Pellet Memorial Woods State Preserve ...
6/10 (305 reviews)
"Very, very clean, just older and dated, and landscaping was rough."

Reviewed on Oct 31, 2024

Days Inn by Wyndham Atlantic
Stuart Motor Lodge
Stuart Motor Lodge
2.5 out of 5
203 SW 7th St, Stuart, IA
The price is $67 per night from Apr 19 to Apr 20
$67
includes taxes & fees
Apr 19 - Apr 20
Stay at this motel in Stuart. Enjoy free WiFi, free parking, and 5 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews.
8.8/10 Excellent! (417 reviews)
Love this place. Comfy beds. Price is good
"Had some issue upon check in but she moved me to another room which was away from guys sitting outside smoking and loud and my room she originally gave me was right next to them and the room itself had some issues the bathroom sink the water just trinkled out and the door was hard to close and could ..."

Reviewed on Apr 14, 2025

Stuart Motor Lodge
Economy Inn Motel
Economy Inn Motel
2.5 out of 5
1216 South Division St, Stuart, IA
The price is $52 per night from Apr 19 to Apr 20
$52
includes taxes & fees
Apr 19 - Apr 20
Stay at this motel in Stuart. Enjoy free WiFi, free parking, and room service.
7.6/10 Good! (109 reviews)
Cheap, clean, and basic
"Price was excellent. Bed was comfy. Shower was hot. Internet was good. Hotel was quite. Pretty much bare-bones. No coffee. Hotel is older and could use some upgrades. But overall, for the price paid, I was happy."

Reviewed on Jan 30, 2025

Economy Inn Motel
See all 36 properties in Guthrie Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.