Hotels Near
Lake Nona Medical City

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Featured Lake Nona Medical City Hotels

Holiday Inn Resort Orlando Suites - Waterpark by IHG
Holiday Inn Resort Orlando Suites - Waterpark by IHG
3.5 out of 5
14500 Continental Gateway, Orlando, FL
Fully refundable
Stay at this 3.5-star family-friendly hotel in Orlando. Enjoy 2 outdoor pools, 5 restaurants, and 2 hot tubs. Our guests praise the clean rooms and the family ...
7.2/10 Good! (2,658 reviews)
"Loved it, would definitely go back"

Reviewed on Apr 15, 2025

Holiday Inn Resort Orlando Suites - Waterpark by IHG
Hyatt Regency Orlando International Airport
Hyatt Regency Orlando International Airport
4 out of 5
9300 Jeff Fuqua Boulevard, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 4-star eco-certified hotel in Orlando. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
9.2/10 Wonderful! (3,196 reviews)
"We really enjoyed the ease of the check in and out procedures. It was very nice to be right at the airport for an early flight. McCoy’s restaurant and bar was amazing. We will definitely stay here again."

Reviewed on Apr 15, 2025

Hyatt Regency Orlando International Airport
Universal's Cabana Bay Beach Resort
Universal's Cabana Bay Beach Resort
3.5 out of 5
6550 Adventure Way, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star family-friendly hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (5,179 reviews)
"It was beautiful. Walkable to the other universal properties."

Reviewed on Apr 15, 2025

Universal's Cabana Bay Beach Resort
Rosen Inn at Pointe Orlando
Rosen Inn at Pointe Orlando
3 out of 5
9000 International Drive, Orlando, FL
Stay at this 3-star family-friendly hotel in Orlando. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the helpful staff in ...
8.4/10 Very Good! (4,164 reviews)
Great
"Great experience we had during the stay for a volleyball tournament. Convenient walking distance to and from Orange county convention center"

Reviewed on Apr 15, 2025

Rosen Inn at Pointe Orlando
DoubleTree by Hilton Hotel Orlando at SeaWorld
DoubleTree by Hilton Hotel Orlando at SeaWorld
4 out of 5
10100 International Drive, Orlando, FL
Stay at this 4-star family-friendly resort in Orlando. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the breakfast and the pool in our ...
7.2/10 Good! (5,848 reviews)
"The room was great. They do need more parking spaces. Pool area was clean and fun."

Reviewed on Apr 14, 2025

DoubleTree by Hilton Hotel Orlando at SeaWorld
Westgate Lakes Resort & Spa Universal Studios Area
Westgate Lakes Resort & Spa Universal Studios Area
4 out of 5
9500 Turkey Lake Rd, Orlando, FL
Stay at this 4-star spa hotel in Orlando. Enjoy free parking, 7 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8/10 Very Good! (4,712 reviews)
"We had a great time at Westgate!! The room was very clean and neat. The rooms were very spacious as well as the patio. The pool area is nice with a jacuzzi and the water park is fun with lots of things for kids to do. I enjoyed the lazy river lol we will be back again."

Reviewed on Apr 13, 2025

Westgate Lakes Resort & Spa Universal Studios Area
DoubleTree by Hilton at the Entrance to Universal Orlando
DoubleTree by Hilton at the Entrance to Universal Orlando
4 out of 5
5780 Major Blvd, Orlando, FL
Stay at this 4-star family-friendly hotel in Orlando. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in ...
8.2/10 Very Good! (6,231 reviews)
Average business hotel
"Business hotel. Very average."

Reviewed on Apr 15, 2025

DoubleTree by Hilton at the Entrance to Universal Orlando
Caribe Royale Orlando
Caribe Royale Orlando
4.5 out of 5
8101 World Center Dr, Orlando, FL
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Orlando. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (3,969 reviews)
"I loved the scavenger hunt to make the stay exciting. Plenty to do on the property. The rooms are huge."

Reviewed on Apr 15, 2025

Caribe Royale Orlando
Hilton Vacation Club Grande Villas Orlando
Hilton Vacation Club Grande Villas Orlando
3.5 out of 5
12118 Turtle Cay Circle, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star family-friendly hotel in Orlando. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the bar in our reviews. ...
9.2/10 Wonderful! (2,935 reviews)
"There"

Reviewed on Apr 15, 2025

Hilton Vacation Club Grande Villas Orlando
Hyatt Regency Orlando
Hyatt Regency Orlando
4.5 out of 5
9801 International Dr, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,634 reviews)
"Good"

Reviewed on Apr 16, 2025

Hyatt Regency Orlando
Vacation Village at Parkway
Vacation Village at Parkway
3 out of 5
2975 Arabian Nights Blvd, Kissimmee, FL
Fully refundableReserve now, pay when you stay
Stay at this 3-star family-friendly condo in Kissimmee. Enjoy free WiFi, 7 outdoor pools, and 7 hot tubs. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,941 reviews)
"I loved the space. Nice and clean."

Reviewed on Apr 14, 2025

Vacation Village at Parkway
Universal's Endless Summer Resort - Dockside Inn and Suites
Universal's Endless Summer Resort - Dockside Inn and Suites
3 out of 5
7125 Universal Boulevard, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 3-star family-friendly hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and 3 bars/lounges. Our guests praise the pool and the restaurant in ...
9/10 Wonderful! (5,269 reviews)
"Great location if going to Universal and right on International Drive so have choice of restaurants and buses to take you to premium outlets or other shops on I drive. Shuttle buses to Universal excellent and also has Avis car rental on site."

Reviewed on Apr 15, 2025

Universal's Endless Summer Resort - Dockside Inn and Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Lake Nona Medical City

Orlando is a city that has a lot going on, but you have your sights set on Lake Nona Medical City. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Lake Nona Medical City has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Lake Nona Medical City hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Orlando so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Lake Nona Medical City underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Lake Nona Medical City city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Lake Nona Medical City cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Lake Nona Medical City at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $95
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Lake Nona Medical City hotel you want, book it, and never look back. Because your great escape is ahead of you.