Hotels Near
Lake Nona Medical City

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Featured Lake Nona Medical City Hotels

DoubleTree by Hilton at the Entrance to Universal Orlando
DoubleTree by Hilton at the Entrance to Universal Orlando
4 out of 5
5780 Major Blvd, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 4-star family-friendly hotel in Orlando. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in ...
8.2/10 Very Good! (6,290 reviews)
"I love this place and will always be coming and staying at this hotel every time I visit Florida thank you for making my stay so amazing love the rooms, the beds and so nice to grab a coffee from Starbucks on the way out! Also the warm cookies they give to you are absolutely amazing a part of me ..."

Reviewed on May 15, 2025

DoubleTree by Hilton at the Entrance to Universal Orlando
Hyatt Regency Orlando International Airport
Hyatt Regency Orlando International Airport
4 out of 5
9300 Jeff Fuqua Boulevard, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 4-star eco-certified hotel in Orlando. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
9.2/10 Wonderful! (3,253 reviews)
"It was decent"

Reviewed on May 13, 2025

Hyatt Regency Orlando International Airport
Westgate Lakes Resort & Spa Universal Studios Area
Westgate Lakes Resort & Spa Universal Studios Area
4 out of 5
9500 Turkey Lake Rd, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Orlando. Enjoy free parking, 7 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8/10 Very Good! (4,911 reviews)
"Will return for another stay"

Reviewed on May 15, 2025

Westgate Lakes Resort & Spa Universal Studios Area
Holiday Inn Resort Orlando Suites - Waterpark by IHG
Holiday Inn Resort Orlando Suites - Waterpark by IHG
3.5 out of 5
14500 Continental Gateway, Orlando, FL
Fully refundable
Stay at this 3.5-star family-friendly hotel in Orlando. Enjoy 2 outdoor pools, 5 restaurants, and 2 hot tubs. Our guests praise the clean rooms and the family ...
7.2/10 Good! (2,938 reviews)
"My"

Reviewed on May 14, 2025

Holiday Inn Resort Orlando Suites - Waterpark by IHG
Universal's Cabana Bay Beach Resort
Universal's Cabana Bay Beach Resort
3.5 out of 5
6550 Adventure Way, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star family-friendly hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (5,215 reviews)
"Family friendly and affordable option to stay in the universal bubble. Use of unlimited bus transfers to universal them parks and city walk is very convenient. Dining options on site that catered for my ceoliac child. Walk next door to volcano bay is very easy or use in site pool facilities."

Reviewed on May 14, 2025

Universal's Cabana Bay Beach Resort
Rosen Inn at Pointe Orlando
Rosen Inn at Pointe Orlando
3 out of 5
9000 International Drive, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 3-star family-friendly hotel in Orlando. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the helpful staff in ...
8.4/10 Very Good! (4,357 reviews)
"Very clean, very friendly staff, perfect location"

Reviewed on May 13, 2025

Rosen Inn at Pointe Orlando
Kompose Boutique Resort at Theme Parks
Kompose Boutique Resort at Theme Parks
4 out of 5
7491 W Irlo Bronson Memorial Hwy, Kissimmee, FL
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly resort in Kissimmee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Disney's Animal Kingdom® Theme ...
9.6/10 Exceptional! (101 reviews)
"great experience"

Reviewed on May 16, 2025

Kompose Boutique Resort at Theme Parks
Vacation Village at Parkway
Vacation Village at Parkway
3 out of 5
2975 Arabian Nights Blvd, Kissimmee, FL
Fully refundableReserve now, pay when you stay
Stay at this 3-star family-friendly condo in Kissimmee. Enjoy free WiFi, 7 outdoor pools, and 7 hot tubs. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (2,103 reviews)
"Easy to get to and navigate around the area."

Reviewed on May 15, 2025

Vacation Village at Parkway
Marriott's Grande Vista
Marriott's Grande Vista
4 out of 5
5925 Avenida Vista, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Orlando. Enjoy free WiFi, 4 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. ...
8.8/10 Excellent! (2,391 reviews)
"Enjoyed the stay at our villa. Very clean and customer service was good."

Reviewed on May 13, 2025

Marriott's Grande Vista
Universal's Endless Summer Resort - Dockside Inn and Suites
Universal's Endless Summer Resort - Dockside Inn and Suites
3 out of 5
7125 Universal Boulevard, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 3-star family-friendly hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and 3 bars/lounges. Our guests praise the pool and the restaurant in ...
9/10 Wonderful! (5,341 reviews)
"We were very happy with the property. The staff were very helpful upon checkin. The rooms were spacious and great for a family of 4."

Reviewed on May 14, 2025

Universal's Endless Summer Resort - Dockside Inn and Suites
Hilton Vacation Club Grande Villas Orlando
Hilton Vacation Club Grande Villas Orlando
3.5 out of 5
12118 Turtle Cay Circle, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star family-friendly hotel in Orlando. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the bar in our reviews. ...
9.2/10 Wonderful! (2,991 reviews)
"Spacious suite, very clean. Couldn't sort out with front desk regarding receiving texts."

Reviewed on May 15, 2025

Hilton Vacation Club Grande Villas Orlando
Sheraton Vistana Villages Resort Villas, I-Drive/Orlando
Sheraton Vistana Villages Resort Villas, I-Drive/Orlando
4 out of 5
12401 International Dr, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 4-star eco-certified hotel in Orlando. Enjoy free WiFi, 5 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in ...
9.2/10 Wonderful! (1,621 reviews)
"This hotel was very clean and the staff were extremely welcoming and kind."

Reviewed on May 14, 2025

Sheraton Vistana Villages Resort Villas, I-Drive/Orlando
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Lake Nona Medical City

Orlando is a city that has a lot going on, but you have your sights set on Lake Nona Medical City. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Lake Nona Medical City has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Lake Nona Medical City hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Orlando so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Lake Nona Medical City underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Lake Nona Medical City city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Lake Nona Medical City cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Lake Nona Medical City at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Lake Nona Medical City hotel you want, book it, and never look back. Because your great escape is ahead of you.