Hotels Near
Lake Nona Medical City

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Featured Lake Nona Medical City Hotels

Holiday Inn Resort Orlando Suites - Waterpark by IHG
Holiday Inn Resort Orlando Suites - Waterpark by IHG
3.5 out of 5
14500 Continental Gateway, Orlando, FL
Fully refundable
Stay at this 3.5-star family-friendly hotel in Orlando. Enjoy 2 outdoor pools, 5 restaurants, and 2 hot tubs. Our guests praise the clean rooms and the family ...
7/10 Good! (2,561 reviews)
"It was enjoyable for my kids"

Reviewed on Apr 6, 2025

Holiday Inn Resort Orlando Suites - Waterpark by IHG
Hyatt Regency Orlando International Airport
Hyatt Regency Orlando International Airport
4 out of 5
9300 Jeff Fuqua Boulevard, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 4-star eco-certified hotel in Orlando. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
9.2/10 Wonderful! (3,201 reviews)
"Being on site for early morning, travel is such a luxury!!!"

Reviewed on Apr 6, 2025

Hyatt Regency Orlando International Airport
Rosen Inn at Pointe Orlando
Rosen Inn at Pointe Orlando
3 out of 5
9000 International Drive, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 3-star family-friendly hotel in Orlando. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the helpful staff in ...
8.4/10 Very Good! (4,123 reviews)
"Great place, great location"

Reviewed on Apr 7, 2025

Rosen Inn at Pointe Orlando
Universal's Cabana Bay Beach Resort
Universal's Cabana Bay Beach Resort
3.5 out of 5
6550 Adventure Way, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star family-friendly hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (5,164 reviews)
"Me and the family absolutely loved staying here. The vibes are just amazing you must take them in to truly understand. Staff was all fantastic room was great price was great pool were great i mean literally nothing to complain about. Will stay again for sure. Its either here or one of the more expensive ..."

Reviewed on Apr 6, 2025

Universal's Cabana Bay Beach Resort
Westgate Lakes Resort & Spa Universal Studios Area
Westgate Lakes Resort & Spa Universal Studios Area
4 out of 5
9500 Turkey Lake Rd, Orlando, FL
Stay at this 4-star spa hotel in Orlando. Enjoy free parking, 7 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8/10 Very Good! (4,673 reviews)
"Grear"

Reviewed on Apr 6, 2025

Westgate Lakes Resort & Spa Universal Studios Area
Caribe Royale Orlando
Caribe Royale Orlando
4.5 out of 5
8101 World Center Dr, Orlando, FL
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Orlando. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (3,948 reviews)
"Parking was bit of an issue. Overall good place to stay."

Reviewed on Apr 6, 2025

Caribe Royale Orlando
DoubleTree by Hilton Hotel Orlando at SeaWorld
DoubleTree by Hilton Hotel Orlando at SeaWorld
4 out of 5
10100 International Drive, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 4-star family-friendly resort in Orlando. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the breakfast and the pool in our ...
7.2/10 Good! (5,814 reviews)
"Staff was great, location makes sea world easy but rooms are a little musty and dated but clean! Mini golf is really run down bht we made the most of it bc my kid loves mg. For a weekend trip wed be back bc of the location to sea world!"

Reviewed on Apr 5, 2025

DoubleTree by Hilton Hotel Orlando at SeaWorld
DoubleTree by Hilton at the Entrance to Universal Orlando
DoubleTree by Hilton at the Entrance to Universal Orlando
4 out of 5
5780 Major Blvd, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 4-star family-friendly hotel in Orlando. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in ...
8.2/10 Very Good! (6,309 reviews)
"The beds could be more comfortable or replaced. Otherwise, it was an amazing stay. Staff were always around asking if they could do anything for you."

Reviewed on Apr 6, 2025

DoubleTree by Hilton at the Entrance to Universal Orlando
Universal's Endless Summer Resort - Dockside Inn and Suites
Universal's Endless Summer Resort - Dockside Inn and Suites
3 out of 5
7125 Universal Boulevard, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 3-star family-friendly hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and 3 bars/lounges. Our guests praise the pool and the restaurant in ...
9/10 Wonderful! (5,293 reviews)
"Great hotel for the price. Everything was clean and staff was friendly."

Reviewed on Apr 6, 2025

Universal's Endless Summer Resort - Dockside Inn and Suites
Hilton Vacation Club Grande Villas Orlando
Hilton Vacation Club Grande Villas Orlando
3.5 out of 5
12118 Turtle Cay Circle, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star family-friendly hotel in Orlando. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the bar in our reviews. ...
9.2/10 Wonderful! (2,921 reviews)
"Great location"

Reviewed on Apr 6, 2025

Hilton Vacation Club Grande Villas Orlando
Hyatt Regency Orlando
Hyatt Regency Orlando
4.5 out of 5
9801 International Dr, Orlando, FL
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,638 reviews)
"Excelent"

Reviewed on Apr 6, 2025

Hyatt Regency Orlando
Vacation Village at Parkway
Vacation Village at Parkway
3 out of 5
2975 Arabian Nights Blvd, Kissimmee, FL
Stay at this 3-star family-friendly condo in Kissimmee. Enjoy free WiFi, 7 outdoor pools, and 7 hot tubs. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,904 reviews)
"10/10 loved staying here"

Reviewed on Apr 4, 2025

Vacation Village at Parkway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Lake Nona Medical City

Orlando is a city that has a lot going on, but you have your sights set on Lake Nona Medical City. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Lake Nona Medical City has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Lake Nona Medical City hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Orlando so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Lake Nona Medical City underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Lake Nona Medical City city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Lake Nona Medical City cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Lake Nona Medical City at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $91
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Lake Nona Medical City hotel you want, book it, and never look back. Because your great escape is ahead of you.