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Hotels in Osceola

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Holiday Inn Osceola by IHG

Holiday Inn Osceola by IHG

3 out of 5
4630 West Keiser Osceola AR
  • 5 min drive from South Mississippi County Regional Medical Center
Stay at this hotel in Osceola. Enjoy free parking, an outdoor pool, and a 24-hour fitness center. Popular attractions Florida Park and Osceola Branch Mississippi ...
8.6/10 Excellent! (24 reviews)
The room was listed incorrectly (said it was a suite that slept 6, but it was just 2 beds) and breakfast is not included. It was clean and new, though.

Reviewed on Mar 21, 2026

Holiday Inn Osceola by IHG
Days Inn & Suites by Wyndham Osceola AR

Days Inn & Suites by Wyndham Osceola AR

2 out of 5
4491 W Keiser Ave Osceola AR
  • 5 min drive from South Mississippi County Regional Medical Center
Stay at this motel in Osceola. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Florida Park and Osceola Branch Mississippi County Library ...
6.4/10 (379 reviews)
This was the worst hotel I have stayed at for at least 25 years. It was dirty, outdated. Staff seemed indifferent.

Reviewed on Mar 20, 2026

Days Inn & Suites by Wyndham Osceola AR
Roadside Inn

Roadside Inn

2.5 out of 5
4635 W Keiser Ave Osceola AR
  • 5 min drive from South Mississippi County Regional Medical Center
Stay at this hotel in Osceola. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Florida Park and Osceola Branch Mississippi County ...
7.4/10 Good! (27 reviews)
We showed up late, at 9:30, no one was in the parking lot, but the lady at the front desk told me they only had one downstairs room left and she has the air on for us. Ok, cool, I'm disabled and can't do stairs due to multiple spine surgeries. But we get into the room and it was only a queen. Also, ...

Reviewed on Mar 18, 2026

Roadside Inn
Econo Lodge

Econo Lodge

2 out of 5
4635 W Keiser Avenue Osceola AR
  • 5 min drive from South Mississippi County Regional Medical Center
Stay at this hotel in Osceola. Enjoy a restaurant. Popular attractions Florida Park and Osceola Branch Mississippi County Library are located nearby.
Econo Lodge
Holiday Inn Blytheville by IHG

Holiday Inn Blytheville by IHG

3 out of 5
1121 E Main St Blytheville AR
  • 39 min drive from South Mississippi County Regional Medical Center
Book a stay at this business-friendly hotel in Blytheville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (672 reviews)
If you want to get sleep, don’t stay here. Walls are thin. Had a couple in the next room with the TV on all night and at 530am their dogs started barking. When telling the front desk all they said was “we will let the manager know.” For over 200 a night not worth it.

Reviewed on Mar 15, 2026

Holiday Inn Blytheville by IHG
Hampton Inn Blytheville

Hampton Inn Blytheville

2.5 out of 5
301 N Service Road, I-55 Blytheville AR
  • 39 min drive from South Mississippi County Regional Medical Center
Book a stay at this business-friendly hotel in Blytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (915 reviews)
Great Staff, clean and quiet hotel.

Reviewed on Mar 28, 2026

Hampton Inn Blytheville
Hampton Inn & Suites Millington

Hampton Inn & Suites Millington

2.5 out of 5
8838 Highway 51 N Millington TN
  • 56 min drive from South Mississippi County Regional Medical Center
Stay at this hotel in Millington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (621 reviews)
didn't use

Reviewed on Mar 18, 2026

Hampton Inn & Suites Millington
Comfort Inn & Suites Blytheville

Comfort Inn & Suites Blytheville

2.5 out of 5
1510 E Main St Blytheville AR
  • 39 min drive from South Mississippi County Regional Medical Center
Book a stay at this business-friendly hotel in Blytheville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (714 reviews)
Pool was nice so was work out room. Our room carpet was dirty, tv did not work door latch was broken. Elevator made strange sounds so we took the stairs and there are chipped broken tiles on landings and carpet was dirty on stairs. The bed was uncomfortable very hard.

Reviewed on Mar 27, 2026

Comfort Inn & Suites Blytheville
The Louis Hotel

The Louis Hotel

4 out of 5
3 Cross Street Wilson AR
  • 23 min drive from South Mississippi County Regional Medical Center
Book a stay at this golf hotel in Wilson. Enjoy free WiFi, free valet parking, and 2 restaurants. Our guests praise the helpful staff in our reviews.
9.6/10 Exceptional! (59 reviews)
Lovely rooms very well appointed boutique hotel

Reviewed on Mar 17, 2026

The Louis Hotel
Holiday Inn Express & Suites Millington by IHG

Holiday Inn Express & Suites Millington by IHG

2.5 out of 5
5090 Cooper Creek Blvd Millington TN
  • 57 min drive from South Mississippi County Regional Medical Center
Book a stay at this business-friendly hotel in Millington. Enjoy free breakfast, free WiFi, and free parking. Popular attractions E A Harrold Park and Harvell ...
8.2/10 Very Good! (517 reviews)
Breakfast was okay. Gym was tiny. Rooms are spacious and

Reviewed on Mar 28, 2026

Holiday Inn Express & Suites Millington by IHG
Springplace Inn & Suites

Springplace Inn & Suites

2 out of 5
7925 U.S. 51 Millington TN
  • 1 hour drive from South Mississippi County Regional Medical Center
Stay at this hotel in Millington. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Millington Branch-Shelby County Public Library ...
5.4/10 (8 reviews)
Despite the Expedia listing saying pets are welcome, there were "No Pets" signs everywhere. They did allow our dogs to stay...for an extra fee we were not anticipating

Reviewed on Mar 18, 2026

Springplace Inn & Suites
Comfort Inn & Suites Atoka-Millington

Comfort Inn & Suites Atoka-Millington

2.5 out of 5
10772 Hwy 51 S. Atoka TN
  • 45 min drive from South Mississippi County Regional Medical Center
Book a stay at this business-friendly hotel in Atoka. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (470 reviews)
We arrived late and left early so I cannot comment on any of the staff except the night desk clerk who was very nice. She even upgraded our room which I very much appreciated. This is an older hotel and fairly outdated in terms of furnishings. The bed slept well though. Our room which was on the ...

Reviewed on Mar 25, 2026

Comfort Inn & Suites Atoka-Millington
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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