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Hotels in Central United States

Choose from 284821 Central United States Hotel Deals

Embassy Suites by Hilton Chicago Downtown River North
Embassy Suites by Hilton Chicago Downtown River North
4 out of 5
600 N State St, Chicago, IL
  • 36 hours drive from Port of Galveston Cruise Terminal
The price is $154 per night from Apr 13 to Apr 14
$154
per night
Apr 13 - Apr 14
Stay at this 4-star hotel in Chicago. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (3,851 reviews)
"Had to take uber to all sights we wanted to visit. Certain foods would run out if you weren’t there early."

Reviewed on Apr 6, 2025

Embassy Suites by Hilton Chicago Downtown River North
Swissotel - Chicago
Swissotel - Chicago
4.5 out of 5
323 E Wacker Dr, Chicago, IL
  • 36 hours drive from Port of Galveston Cruise Terminal
The price is $212 per night from Apr 16 to Apr 17
$212
per night
Apr 16 - Apr 17
Book a stay at this eco-certified hotel in Chicago. Enjoy 2 bars/lounges, breakfast (surcharge), and 24-hour room service. Our guests praise the restaurant and ...
8.8/10 Excellent! (2,038 reviews)
"Great place to stay when in downtown Chicago. Close to everything and beautiful property."

Reviewed on Apr 7, 2025

Swissotel - Chicago
Crowne Plaza Chicago West Loop by IHG
Crowne Plaza Chicago West Loop by IHG
3.5 out of 5
25 South Halsted Street, Chicago, IL
  • 36 hours drive from Port of Galveston Cruise Terminal
The price is $108 per night from Apr 20 to Apr 21
$108
per night
Apr 20 - Apr 21
Stay at this 3.5-star business-friendly hotel in Chicago. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff in ...
8.6/10 Excellent! (1,013 reviews)
"The property is awesome! The only issue is I have severe allergies and I can tell that there was an animal in the room prior to me."

Reviewed on Apr 4, 2025

Crowne Plaza Chicago West Loop by IHG
Isla Grand Beach Resort
Isla Grand Beach Resort
3.5 out of 5
500 Padre Blvd., South Padre Island, TX
  • 8 hours drive from Port of Galveston Cruise Terminal
The price is $153 per night from Apr 8 to Apr 9
$153
per night
Apr 8 - Apr 9
Book a stay at this beach hotel in South Padre Island. Enjoy free parking, 2 outdoor pools, and a beach locale. Our guests praise the pool and the helpful staff ...
8.2/10 Very Good! (1,242 reviews)
"Staff was amazing and they where super friendly about us having our pet Roxy ❤️"

Reviewed on Apr 1, 2025

Isla Grand Beach Resort
Hilton Chicago/Magnificent Mile Suites
Hilton Chicago/Magnificent Mile Suites
3.5 out of 5
198 E Delaware Pl, Chicago, IL
  • 36 hours drive from Port of Galveston Cruise Terminal
The price is $139 per night from Apr 21 to Apr 22
$139
per night
Apr 21 - Apr 22
Book a stay at this business-friendly hotel in Chicago. Enjoy a fitness center, valet parking (surcharge), and a 24-hour front desk. Our guests praise the helpful ...
8.8/10 Excellent! (2,096 reviews)
"The staff were nice and assisted with our family stay needs"

Reviewed on Apr 4, 2025

Hilton Chicago/Magnificent Mile Suites
Crowne Plaza New Orleans French Qtr - Astor by IHG
Crowne Plaza New Orleans French Qtr - Astor by IHG
4.5 out of 5
739 Canal Street at Bourbon, New Orleans, LA
The price is $142 per night from Apr 14 to Apr 15
$142
per night
Apr 14 - Apr 15
Stay at this 4.5-star luxury hotel in New Orleans. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the helpful ...
7.4/10 Good! (4,276 reviews)
"The staff was pleasant, the property was beautiful and clean."

Reviewed on Apr 6, 2025

Crowne Plaza New Orleans French Qtr - Astor by IHG
Congress Plaza Hotel
Congress Plaza Hotel
3.5 out of 5
520 South Michigan Avenue, Chicago, IL
  • 36 hours drive from Port of Galveston Cruise Terminal
The price is $147 per night from Apr 13 to Apr 14
$147
per night
Apr 13 - Apr 14
Book a stay at this business-friendly hotel in Chicago. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (8,634 reviews)
"Property is a little outdated, but overall in great condition."

Reviewed on Apr 1, 2025

Congress Plaza Hotel
Wyndham New Orleans - French Quarter
Wyndham New Orleans - French Quarter
4 out of 5
124 Royal St, New Orleans, LA
The price is $162 per night from Apr 14 to Apr 15
$162
per night
Apr 14 - Apr 15
Book a stay at this business-friendly hotel in New Orleans. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.4/10 Very Good! (3,781 reviews)
"The hotel was very well kept and clean"

Reviewed on Apr 6, 2025

Wyndham New Orleans - French Quarter
Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
  • 1 hour drive from Port of Galveston Cruise Terminal
The price is $125 per night from Apr 9 to Apr 10
$125
per night
Apr 9 - Apr 10
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,231 reviews)
"His was a nice affordable hotel in the middle of downtown. I would recommend"

Reviewed on Apr 7, 2025

Club Quarters Hotel Downtown, Houston
Sonesta Hotel Houston IAH Airport
Sonesta Hotel Houston IAH Airport
4 out of 5
425 North Sam Houston Parkway East, Houston, TX
  • 2 hours drive from Port of Galveston Cruise Terminal
The price is $94 per night from Apr 25 to Apr 26
$94
per night
Apr 25 - Apr 26
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
7.4/10 Good! (1,012 reviews)
"Pretty good hotel to stay at, it's comfortable quiet and clean."

Reviewed on Apr 5, 2025

Sonesta Hotel Houston IAH Airport
Maison Dupuy Hotel
Maison Dupuy Hotel
3.5 out of 5
1001 Toulouse St, New Orleans, LA
The price is $126 per night from May 5 to May 6
$126
per night
May 5 - May 6
Book a stay at this historic hotel in New Orleans. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the pool and the restaurant ...
7.6/10 Good! (2,257 reviews)
"The location was great. Very convenient to everything in the French Quarter. Property is in need of an update."

Reviewed on Apr 6, 2025

Maison Dupuy Hotel
Hyatt Place Nashville Downtown
Hyatt Place Nashville Downtown
3 out of 5
301 3rd Ave S, Nashville, TN
  • 19 hours drive from Port of Galveston Cruise Terminal
The price is $249 per night from Apr 13 to Apr 14
$249
per night
Apr 13 - Apr 14
Stay at this 3-star business-friendly hotel in Nashville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (5,005 reviews)
"Great option for. Broadway"

Reviewed on Apr 7, 2025

Hyatt Place Nashville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central United States

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central United States.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central United States’s 284,821 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $94. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central United States hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central United States. No matter your reason for visiting Central United States, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central United States hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central United States for as low as $94.

How many hotels are there in Central United States?

With over 284,821 hotels in Central United States, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $94.

How to find cheap car rentals in Central United States?

Finding a cheap car rental deal in Central United States is as easy as scoring cheap hotels in Central United States. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.