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Hotels in Central United States

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Gaylord Opryland Resort & Convention Center

Gaylord Opryland Resort & Convention Center

4 out of 5
2800 Opryland Drive Nashville TN
  • 18 hours drive from River Walk
Book a stay at this spa resort in Nashville. Enjoy 2 outdoor pools, a full-service spa, and 18 restaurants. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,763 reviews)
Room was not worth $500 a night! They had me in a basic little room and the tub holds water in it while you shower! The toilet was not fully emptying when you flush it. My fitted sheet had holes in them when I arrived, but they did come and exchange them for better sheets. I loved the scenery and ...

Reviewed on Dec 21, 2025

Gaylord Opryland Resort & Convention Center
Hilton Chicago/Magnificent Mile Suites

Hilton Chicago/Magnificent Mile Suites

3.5 out of 5
198 E Delaware Pl Chicago IL
  • 37 hours drive from River Walk
Book a stay at this business-friendly hotel in Chicago. Enjoy a fitness center, valet parking (surcharge), and a 24-hour front desk. Our guests praise the helpful ...
8.8/10 Excellent! (3,562 reviews)
Great front desk service

Reviewed on Dec 25, 2025

Hilton Chicago/Magnificent Mile Suites
Palmer House a Hilton Hotel

Palmer House a Hilton Hotel

4 out of 5
17 E Monroe St Chicago IL
  • 37 hours drive from River Walk
Book a stay at this luxury hotel in Chicago. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful staff ...
8.4/10 Very Good! (2,168 reviews)
Decent room and the staff at the front desk and restaurant were friendly and helpful. The front desk area is cramped and confusing (i.e.) once you get your key card from check-in, it is so tight in that area that that it’s unclear how you get out of the area without pushing past the people in line ...

Reviewed on Dec 22, 2025

Palmer House a Hilton Hotel
The Westin New Orleans

The Westin New Orleans

4.5 out of 5
100 Rue Iberville New Orleans LA
Book a stay at this luxury hotel in New Orleans. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (2,315 reviews)
Room was very clean, great location, everything was in walking distance. The only issue was not all the elevators were functional to get to the lobby from street level. Lobby bar was always a fun first stop to start your night.

Reviewed on Dec 27, 2025

The Westin New Orleans
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
  • 2 hours drive from River Walk
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (3,128 reviews)
Spear blanket kept in the closet was needed and we found out was dirty and sticky

Reviewed on Dec 21, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Silversmith Hotel Chicago Downtown

Silversmith Hotel Chicago Downtown

4 out of 5
10 S Wabash Ave Chicago IL
  • 37 hours drive from River Walk
Book a stay at this business-friendly hotel in Chicago. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9.2/10 Wonderful! (2,145 reviews)
Excellent stay

Reviewed on Dec 21, 2025

Silversmith Hotel Chicago Downtown
Club Quarters Hotel Wacker at Michigan, Chicago

Club Quarters Hotel Wacker at Michigan, Chicago

4 out of 5
75 E Wacker Dr Chicago IL
  • 37 hours drive from River Walk
Book a stay at this business-friendly hotel in Chicago. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (2,006 reviews)
The hotel was great! Clean and spacious and I would stay there again. (Not in the same room but i would stay in the same hotel.) However, we were placed on the 40th floor in the only room on that floor with the elevator directly behind the bed. Every time the elevator moved, we heard loud mechanical ...

Reviewed on Dec 22, 2025

Club Quarters Hotel Wacker at Michigan, Chicago
Hilton Chicago

Hilton Chicago

4 out of 5
720 S Michigan Ave Chicago IL
  • 37 hours drive from River Walk
Book a stay at this historic hotel in Chicago. Enjoy 2 restaurants, breakfast (surcharge), and a health club. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (2,416 reviews)
Very friendly staff.

Reviewed on Dec 26, 2025

Hilton Chicago
New Orleans Marriott

New Orleans Marriott

4 out of 5
555 Canal St New Orleans LA
Book a stay at this business-friendly hotel in New Orleans. Enjoy 2 restaurants, breakfast (surcharge), and room service. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,747 reviews)
Amazing room amd view. Super clean

Reviewed on Dec 27, 2025

New Orleans Marriott
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
  • 2 hours drive from River Walk
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.4/10 Very Good! (3,963 reviews)
Excellent stay! The hotel was decorated elegantly for the holidays and I was offered a room upgrade due to an issue with the kiosk saying the room was not ready even though it was after 3 pm which is check in time. The Rusk rooms were very accommodating and spacious. I especially enjoyed the view ...

Reviewed on Dec 22, 2025

Club Quarters Hotel Downtown, Houston
The Pfister Hotel

The Pfister Hotel

4.5 out of 5
424 E Wisconsin Ave Milwaukee WI
  • 35 hours drive from River Walk
Book a stay at this luxury hotel in Milwaukee. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the clean rooms ...
9.4/10 Exceptional! (1,835 reviews)
Gorgeous hotel, friendly staff, champagne at check in, comfortable beds!

Reviewed on Dec 22, 2025

The Pfister Hotel
Comfort Inn Downtown Nashville - Music City Center

Comfort Inn Downtown Nashville - Music City Center

3 out of 5
1501 Demonbreun St Nashville TN
  • 18 hours drive from River Walk
Book a stay at this business-friendly hotel in Nashville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the pool ...
8/10 Very Good! (3,346 reviews)
The location, room and the staff were very friendly and breakfast was excellent too.

Reviewed on Dec 24, 2025

Comfort Inn Downtown Nashville - Music City Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central United States

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $89. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central United States hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central United States. No matter your reason for visiting Central United States, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central United States hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Central United States?

With over 301,949 hotels in Central United States, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $89.

How to find cheap car rentals in Central United States?

Finding a cheap car rental deal in Central United States is as easy as scoring cheap hotels in Central United States. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.