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Hotels in Central United States

Choose from 277524 Central United States Hotel Deals

Congress Plaza Hotel
Congress Plaza Hotel
3.5 out of 5
520 South Michigan Avenue, Chicago, IL
  • 43 hours drive from Padre Island National Seashore
The price is $115 per night from Nov 24 to Nov 25
$115
includes taxes & fees
Nov 24 - Nov 25
Book a stay at this business-friendly hotel in Chicago. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (8,090 reviews)
"Found a big cockroach in my friends room"

Reviewed on Nov 17, 2024

Congress Plaza Hotel
Gaylord Opryland Resort & Convention Center
Gaylord Opryland Resort & Convention Center
4 out of 5
2800 Opryland Drive, Nashville, TN
  • 25 hours drive from Padre Island National Seashore
The price is $477 per night from Dec 2 to Dec 3
$477
includes taxes & fees
Dec 2 - Dec 3
Book a stay at this spa resort in Nashville. Enjoy 2 outdoor pools, a full-service spa, and 18 restaurants. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,623 reviews)
"great place"

Reviewed on Nov 15, 2024

Gaylord Opryland Resort & Convention Center
River Hotel
River Hotel
4 out of 5
75 East Wacker Drive, Chicago, IL
  • 43 hours drive from Padre Island National Seashore
The price is $123 per night from Dec 18 to Dec 19
$123
includes taxes & fees
Dec 18 - Dec 19
Stay at this 4-star business-friendly hotel in Chicago. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (3,544 reviews)
"This hotel is a wonderful place, I was there around 8:00 on the 14th of November and The Man Behind The Desk was exceptional! He went above and beyond to get me the room that I was asking for. I did not get the gentleman's name but this hotel needs more people just like him. The River Hotel on Wacker ..."

Reviewed on Nov 16, 2024

River Hotel
Hollywood Casino at Greektown
Hollywood Casino at Greektown
4 out of 5
1200 Saint Antoine St, Detroit, MI
  • 43 hours drive from Padre Island National Seashore
The price is $193 per night from Nov 19 to Nov 20
$193
includes taxes & fees
Nov 19 - Nov 20
Stay at this 4-star business-friendly hotel in Detroit. Enjoy 5 restaurants, a casino, and 5 bars/lounges. Our guests praise the helpful staff and the convenient ...
8.6/10 Excellent! (2,596 reviews)
"I really enjoyed my stay!"

Reviewed on Nov 16, 2024

Hollywood Casino at Greektown
Crowne Plaza New Orleans French Qtr - Astor
Crowne Plaza New Orleans French Qtr - Astor
4.5 out of 5
739 Canal Street at Bourbon, New Orleans, LA
  • 7 hours drive from Padre Island National Seashore
The price is $116 per night from Nov 24 to Nov 25
$116
includes taxes & fees
Nov 24 - Nov 25
Stay at this 4.5-star luxury hotel in New Orleans. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the helpful ...
7.2/10 Good! (3,495 reviews)
"Had an amazing time"

Reviewed on Nov 16, 2024

Crowne Plaza New Orleans French Qtr - Astor
The Westin Michigan Avenue Chicago
The Westin Michigan Avenue Chicago
4.5 out of 5
909 North Michigan Ave, Chicago, IL
  • 43 hours drive from Padre Island National Seashore
The price is $194 per night from Dec 15 to Dec 16
$194
includes taxes & fees
Dec 15 - Dec 16
Book a stay at this spa hotel in Chicago. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,002 reviews)
"Location couldn’t be better. Property shows a little wear and our room didn’t have much of a view, but the bed was comfortable and the room was quiet."

Reviewed on Nov 11, 2024

The Westin Michigan Avenue Chicago
Club Quarters Hotel, Central Loop, Chicago
Club Quarters Hotel, Central Loop, Chicago
4 out of 5
111 West Adams Street, Chicago, IL
  • 43 hours drive from Padre Island National Seashore
The price is $119 per night from Dec 18 to Dec 19
$119
includes taxes & fees
Dec 18 - Dec 19
Stay at this 4-star business-friendly hotel in Chicago. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.4/10 Very Good! (3,249 reviews)
"This was perfect hotel for people traveling who want an easy and convenient stay in central chicago near the loop! Plus also loved the soap / lotion brand they use for there toiletries."

Reviewed on Nov 15, 2024

Club Quarters Hotel, Central Loop, Chicago
Eurostars Magnificent Mile
Eurostars Magnificent Mile
4 out of 5
660 North State Street, Chicago, IL
  • 43 hours drive from Padre Island National Seashore
The price is $158 per night from Dec 17 to Dec 18
$158
includes taxes & fees
Dec 17 - Dec 18
Stay at this 4-star spa hotel in Chicago. Enjoy free WiFi, a full-service spa, and a fitness center. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (2,738 reviews)
"It was beautiful, clean, amazing views staff was great restaurants nearby"

Reviewed on Nov 15, 2024

Eurostars Magnificent Mile
Riverwalk Plaza
Riverwalk Plaza
4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
  • 7 hours drive from Padre Island National Seashore
The price is $129 per night from Nov 19 to Nov 20
$129
includes taxes & fees
Nov 19 - Nov 20
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the ...
8.2/10 Very Good! (4,256 reviews)
"Good Location- Close to main tourist sites"

Reviewed on Nov 15, 2024

Riverwalk Plaza
Comfort Inn Downtown Nashville - Music City Center
Comfort Inn Downtown Nashville - Music City Center
3 out of 5
1501 Demonbreun St, Nashville, TN
  • 25 hours drive from Padre Island National Seashore
The price is $107 per night from Nov 24 to Nov 25
$107
includes taxes & fees
Nov 24 - Nov 25
Stay at this 3-star business-friendly hotel in Nashville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the pool ...
8/10 Very Good! (1,209 reviews)
"The staff was on top of everything"

Reviewed on Nov 16, 2024

Comfort Inn Downtown Nashville - Music City Center
Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
  • 8 hours drive from Padre Island National Seashore
The price is $112 per night from Dec 18 to Dec 19
$112
includes taxes & fees
Dec 18 - Dec 19
Stay at this 4-star aparthotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful staff in ...
8.2/10 Very Good! (3,065 reviews)
"I really enjoyed my stay at club quarters- I was alone and the staff were extremely friendly and helpful- welcoming you every time you entered or left! Looking after luggage etc. Easy to walk to the convention I attended and lots of eating places within 5-6 blocks! Room was nearby the elevator so ..."

Reviewed on Nov 15, 2024

Club Quarters Hotel Downtown, Houston
Omni Dallas Hotel
Omni Dallas Hotel
4 out of 5
555 S Lamar St, Dallas, TX
  • 16 hours drive from Padre Island National Seashore
The price is $232 per night from Nov 24 to Nov 25
$232
includes taxes & fees
Nov 24 - Nov 25
Stay at this 4-star luxury hotel in Dallas. Enjoy a full-service spa, 5 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,351 reviews)
"Good dining options within the hotel. Furniture needs to be touched up."

Reviewed on Nov 13, 2024

Omni Dallas Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Central United States

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Central United States hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central United States.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central United States’s 277,524 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $107. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Central United States hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central United States. No matter your reason for visiting Central United States, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central United States hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central United States for as low as $107.

How many hotels are there in Central United States?

With over 277,524 hotels in Central United States, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $107.

How to find cheap car rentals in Central United States?

Finding a cheap car rental deal in Central United States is as easy as scoring cheap hotels in Central United States. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Central United States now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Central United States right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.