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Hotels in Central United States

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Choose from 312195 Central United States Hotel Deals

Congress Plaza Hotel

Congress Plaza Hotel

3.5 out of 5
520 South Michigan Avenue Chicago IL
  • 13 min drive from Wrigley Field
Book a stay at this business-friendly hotel in Chicago. Enjoy 2 restaurants, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and ...
8/10 Very Good! (10,160 reviews)
"Hotel was clean, staff friendly. Old hotel that is being improved. Our room was small but otherwise good for our purposes. Good spot that launch our adventure!"

Reviewed on Jun 3, 2026

Congress Plaza Hotel
Holiday Inn Express & Suites Galveston Beach by IHG

Holiday Inn Express & Suites Galveston Beach by IHG

2.5 out of 5
3228 SEAWALL BOULEVARD Galveston TX
  • 37 hours drive from Wrigley Field
Book a stay at this business-friendly hotel in Galveston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,324 reviews)
"Great location and breakfast"

Reviewed on May 29, 2026

Holiday Inn Express & Suites Galveston Beach by IHG
Gaylord Opryland Resort & Convention Center

Gaylord Opryland Resort & Convention Center

4 out of 5
2800 Opryland Drive Nashville TN
  • 16 hours drive from Wrigley Field
Book a stay at this spa resort in Nashville. Enjoy 2 outdoor pools, a full-service spa, and 18 restaurants. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,777 reviews)
"Beautiful property and comfortable rooms! Loved the waterfalls and landscaping. Enjoyed the live music, the sports bar, and especially the view from our balcony room which A. D. convinced us to upgrade to! He was especially kind and helpful. Stayed one night, would like to see that parking is complimentary ..."

Reviewed on Jun 1, 2026

Gaylord Opryland Resort & Convention Center
Hyatt Regency O'Hare Chicago

Hyatt Regency O'Hare Chicago

4 out of 5
9300 Bryn Mawr Ave Rosemont IL
  • 16 min drive from Wrigley Field
Book a stay at this business-friendly hotel in Rosemont. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.8/10 Excellent! (2,606 reviews)
"Beautiful hotel! I found it very challenging to spend cash on site. Would have been nice to know ahead of time that this was a cash free hotel only. Minor inconvenience having to run back to the room to retrieve a cc."

Reviewed on Jun 3, 2026

Hyatt Regency O'Hare Chicago
Bourbon Orleans Hotel

Bourbon Orleans Hotel

4 out of 5
717 Orleans St. New Orleans LA
  • 33 hours drive from Wrigley Field
Book a stay at this historic hotel in New Orleans. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the pool and the helpful staff ...
9.2/10 Wonderful! (4,089 reviews)
"Old world feel - elegant - - - Concierge service was excellent - Location was central French Quarter so walkable - there were building water problems but was being dealt with - overall was very pleased with"

Reviewed on Jun 3, 2026

Bourbon Orleans Hotel
The Chicago Hotel Collection - Magnificent Mile

The Chicago Hotel Collection - Magnificent Mile

4 out of 5
166 E Superior Street Chicago IL
  • 9 min drive from Wrigley Field
Book a stay at this boutique hotel in Chicago. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in ...
7.8/10 Good! (1,507 reviews)
"What an amazing place! The staff was so welcoming when we first arrived and so helpful - especially Raymond at the front desk! The location is perfect, we could walk everywhere. And the rooftop bar was great, at night if we felt like staying in we could just go upstairs and have a drink and relax. ..."

Reviewed on Jun 3, 2026

The Chicago Hotel Collection - Magnificent Mile
Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago

4 out of 5
150 East Ontario Street Chicago IL
  • 10 min drive from Wrigley Field
Book a stay at this business-friendly hotel in Chicago. Enjoy free breakfast, free WiFi, and 2 bars/lounges. Popular attractions Michigan Avenue and Chicago ...
9.4/10 Exceptional! (4,324 reviews)
"Clean room, the breakfast was great, and the lobby bar serves a really good guava lemon drop!"

Reviewed on Jun 3, 2026

Hotel Riu Plaza Chicago
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
  • 34 hours drive from Wrigley Field
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,010 reviews)
"Overall great hotel. Definitely will be staying here again. Shout out to the staff crew."

Reviewed on May 30, 2026

Hotel Zaza Houston Museum District
Hyatt Place Nashville Downtown

Hyatt Place Nashville Downtown

3 out of 5
301 3rd Ave S Nashville TN
  • 16 hours drive from Wrigley Field
Book a stay at this business-friendly hotel in Nashville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.2/10 Wonderful! (6,081 reviews)
"The rooms were big and spacious. Everything was clean, and it was a perfect location downtown."

Reviewed on Jun 3, 2026

Hyatt Place Nashville Downtown
The Chicago Hotel Collection Ambassador Gold Coast

The Chicago Hotel Collection Ambassador Gold Coast

4 out of 5
1301 N State Pkwy Chicago IL
  • 8 min drive from Wrigley Field
Book a stay at this business-friendly hotel in Chicago. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the helpful ...
8.2/10 Very Good! (1,531 reviews)
"N/A"

Reviewed on Jun 3, 2026

The Chicago Hotel Collection Ambassador Gold Coast
Beachside Resort Hotel

Beachside Resort Hotel

2 out of 5
610 W Beach Blvd Gulf Shores AL
  • 33 hours drive from Wrigley Field
Stay at this hotel in Gulf Shores. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
8/10 Very Good! (1,648 reviews)
"Check in was good. The ladies at the desk were very nice ."

Reviewed on Jun 2, 2026

Beachside Resort Hotel
Margaritaville Beach Resort South Padre Island

Margaritaville Beach Resort South Padre Island

4 out of 5
310 Padre Blvd South Padre Island TX
  • 42 hours drive from Wrigley Field
Book a stay at this beach hotel in South Padre Island. Enjoy a full-service spa, a beach locale, and breakfast (surcharge). Our guests praise the pool and the ...
8.6/10 Excellent! (2,296 reviews)
"First room they put us in was so humid that the bed felt wet and we found mold in the curtains. They changed us rooms and the second room was just as humid and had good knows what type of stains on the bed, we checked out and demanded a refund which was given"

Reviewed on Jun 2, 2026

Margaritaville Beach Resort South Padre Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central United States

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central United States.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central United States’s 312,195 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $137. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central United States hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central United States. No matter your reason for visiting Central United States, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central United States hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central United States for as low as $137.

How many hotels are there in Central United States?

With over 312,195 hotels in Central United States, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $137.

How to find cheap car rentals in Central United States?

Finding a cheap car rental deal in Central United States is as easy as scoring cheap hotels in Central United States. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.