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Hotels in Central United States

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Choose from 312775 Central United States Hotel Deals

Congress Plaza Hotel

Congress Plaza Hotel

3.5 out of 5
520 South Michigan Avenue Chicago IL
  • 13 min drive from Wrigley Field
Book a stay at this business-friendly hotel in Chicago. Enjoy 2 restaurants, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and ...
8/10 Very Good! (10,251 reviews)
"The only negative I had with the hotel was that their food choices were limited, and there were not a lot of healthy options. I would have really appreciated more veg choices with the meals, and more salad options."

Reviewed on Jun 12, 2026

Congress Plaza Hotel
Gaylord Opryland Resort & Convention Center

Gaylord Opryland Resort & Convention Center

4 out of 5
2800 Opryland Drive Nashville TN
  • 16 hours drive from Wrigley Field
Book a stay at this spa resort in Nashville. Enjoy 2 outdoor pools, a full-service spa, and 18 restaurants. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,789 reviews)
"Our family loves staying here! The spa is incredible!"

Reviewed on Jun 11, 2026

Gaylord Opryland Resort & Convention Center
Hyatt Regency O'Hare Chicago

Hyatt Regency O'Hare Chicago

4 out of 5
9300 Bryn Mawr Ave Rosemont IL
  • 16 min drive from Wrigley Field
Book a stay at this business-friendly hotel in Rosemont. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.8/10 Excellent! (2,656 reviews)
"I really liked it and recommend it."

Reviewed on Jun 12, 2026

Hyatt Regency O'Hare Chicago
Hilton Cincinnati Netherland Plaza

Hilton Cincinnati Netherland Plaza

4 out of 5
35 W 5th St Cincinnati OH
  • 8 hours drive from Wrigley Field
Book a stay at this luxury hotel in Cincinnati. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,546 reviews)
"I had an unexpected trip out to Cincinnati because my elderly mother went to a trip and got sick and I had to fly out to get her. I took her to stay at this hotel for a day and a half while we waited for our flight to fly out, she rested recuperated and we went downstairs to the restaurant whenever ..."

Reviewed on Jun 11, 2026

Hilton Cincinnati Netherland Plaza
The Chicago Hotel Collection - Magnificent Mile

The Chicago Hotel Collection - Magnificent Mile

4 out of 5
166 E Superior Street Chicago IL
  • 9 min drive from Wrigley Field
Book a stay at this boutique hotel in Chicago. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in ...
7.8/10 Good! (1,568 reviews)
"I"

Reviewed on Jun 12, 2026

The Chicago Hotel Collection - Magnificent Mile
Beachside Resort Hotel

Beachside Resort Hotel

2 out of 5
610 W Beach Blvd Gulf Shores AL
  • 33 hours drive from Wrigley Field
Stay at this hotel in Gulf Shores. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
8/10 Very Good! (1,665 reviews)
"Floors appeared soiled but could be due to age"

Reviewed on Jun 12, 2026

Beachside Resort Hotel
The Chicago Hotel Collection Ambassador Gold Coast

The Chicago Hotel Collection Ambassador Gold Coast

4 out of 5
1301 N State Pkwy Chicago IL
  • 8 min drive from Wrigley Field
Book a stay at this business-friendly hotel in Chicago. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the helpful ...
8.2/10 Very Good! (1,591 reviews)
"Was okay, small room with a poor view, didn’t have the rollaway bed ready had to be requested separately. Overall wasn’t terribly impressed it was an overpriced Travelodge"

Reviewed on Jun 12, 2026

The Chicago Hotel Collection Ambassador Gold Coast
Bourbon Orleans Hotel

Bourbon Orleans Hotel

4 out of 5
717 Orleans St. New Orleans LA
  • 33 hours drive from Wrigley Field
Book a stay at this historic hotel in New Orleans. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the pool and the helpful staff ...
9.2/10 Wonderful! (4,128 reviews)
"I love this hotel…an absolute classic. The rooms are clean, roomy enough, and the staff is hospitable without being stuffy. The linens are high thread count and comfy. The salt water swimming pool is devine. I almost hesitate to tell you how fabulous it is, lest you occupy my favorite lounger in ..."

Reviewed on Jun 12, 2026

Bourbon Orleans Hotel
Best Western Downtown Plus Music Row

Best Western Downtown Plus Music Row

3.5 out of 5
1407 Division Street Nashville TN
  • 16 hours drive from Wrigley Field
Book a stay at this family-friendly hotel in Nashville. Enjoy free breakfast, an outdoor pool, and a fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (3,720 reviews)
"It was ok. Staff was friendly"

Reviewed on Jun 11, 2026

Best Western Downtown Plus Music Row
Margaritaville Beach Resort South Padre Island

Margaritaville Beach Resort South Padre Island

4 out of 5
310 Padre Blvd South Padre Island TX
  • 42 hours drive from Wrigley Field
Book a stay at this beach hotel in South Padre Island. Enjoy a full-service spa, a beach locale, and breakfast (surcharge). Our guests praise the pool and the ...
8.6/10 Excellent! (2,316 reviews)
"Excellent for families! Great voews and beach access!"

Reviewed on Jun 12, 2026

Margaritaville Beach Resort South Padre Island
Hyatt Place Nashville Downtown

Hyatt Place Nashville Downtown

3 out of 5
301 3rd Ave S Nashville TN
  • 16 hours drive from Wrigley Field
Book a stay at this business-friendly hotel in Nashville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.2/10 Wonderful! (6,124 reviews)
"Very comfortable and clean hotel. Staff was helpful and welcoming."

Reviewed on Jun 12, 2026

Hyatt Place Nashville Downtown
Hotel Felix River North/Magnificent Mile

Hotel Felix River North/Magnificent Mile

4 out of 5
111 W Huron St Chicago IL
  • 9 min drive from Wrigley Field
Book a stay at this boutique hotel in Chicago. Enjoy breakfast (surcharge), a 24-hour health club, and valet parking (surcharge). Our guests praise the helpful ...
8.2/10 Very Good! (2,785 reviews)
"First I was thinking that the hotel is a good place. The location was very good close to tourist attractions. The room I had reserved was on top floor which I was expecting a view but the room had a small window facing some other building rooms.the room had issues at the beginning which was the toilet ..."

Reviewed on Jun 11, 2026

Hotel Felix River North/Magnificent Mile
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central United States

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central United States.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central United States’s 312,775 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $119. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central United States hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central United States. No matter your reason for visiting Central United States, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central United States hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central United States for as low as $119.

How many hotels are there in Central United States?

With over 312,775 hotels in Central United States, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $119.

How to find cheap car rentals in Central United States?

Finding a cheap car rental deal in Central United States is as easy as scoring cheap hotels in Central United States. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.