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Hotels in Central United States

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Tonight Feb 22 - Feb 23Next weekend Feb 28 - Mar 2

Choose from 283050 Central United States Hotel Deals

Hollywood Casino at Greektown
Hollywood Casino at Greektown
4 out of 5
1200 Saint Antoine St, Detroit, MI
  • 37 hours drive from Port of Galveston Cruise Terminal
The price is $184 per night from Feb 23 to Feb 24
$184
includes taxes & fees
Feb 23 - Feb 24
Stay at this 4-star business-friendly hotel in Detroit. Enjoy 5 restaurants, a casino, and 5 bars/lounges. Our guests praise the helpful staff and the convenient ...
8.6/10 Excellent! (3,226 reviews)
"Great location and room was clean."

Reviewed on Feb 19, 2025

Hollywood Casino at Greektown
River Hotel
River Hotel
4 out of 5
75 East Wacker Drive, Chicago, IL
  • 36 hours drive from Port of Galveston Cruise Terminal
The price is $103 per night from Feb 27 to Feb 28
$103
includes taxes & fees
Feb 27 - Feb 28
Stay at this 4-star business-friendly hotel in Chicago. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (3,799 reviews)
"Located across the street from the River walkway and a couple of blocks from shopping, restaurants and Starbucks Reserve."

Reviewed on Feb 20, 2025

River Hotel
Congress Plaza Hotel
Congress Plaza Hotel
3.5 out of 5
520 South Michigan Avenue, Chicago, IL
  • 36 hours drive from Port of Galveston Cruise Terminal
The price is $115 per night from Feb 23 to Feb 24
$115
includes taxes & fees
Feb 23 - Feb 24
Book a stay at this business-friendly hotel in Chicago. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (8,522 reviews)
"GOOD: beautiful historic hotel with large rooms and bathrooms, good area, good front desk service. BAD - We stayed Fri - Mon. When we came back late in the afternoon, the room was not cleaned, beds were not made both days. Long corridors' and doors' paint is peeling. No curtain rods."

Reviewed on Feb 21, 2025

Congress Plaza Hotel
L7 Chicago by LOTTE
L7 Chicago by LOTTE
4.5 out of 5
225 N Wabash Ave, Chicago, IL
  • 36 hours drive from Port of Galveston Cruise Terminal
The price is $163 per night from Feb 23 to Feb 24
$163
includes taxes & fees
Feb 23 - Feb 24
Book a stay at this boutique hotel in Chicago. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and ...
9.6/10 Exceptional! (1,673 reviews)
"It was a great experience"

Reviewed on Feb 20, 2025

L7 Chicago by LOTTE
Riverwalk Plaza
Riverwalk Plaza
4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
  • 5 hours drive from Port of Galveston Cruise Terminal
The price is $152 per night from Feb 23 to Feb 24
$152
includes taxes & fees
Feb 23 - Feb 24
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the ...
8/10 Very Good! (4,701 reviews)
"Great location! Enjoyed dinner at the restaurant located inside the hotel. Their coffee shop was great!"

Reviewed on Feb 20, 2025

Riverwalk Plaza
Hilton Garden Inn Chicago Downtown/Magnificent Mile
Hilton Garden Inn Chicago Downtown/Magnificent Mile
3 out of 5
10 E Grand Ave, Chicago, IL
  • 36 hours drive from Port of Galveston Cruise Terminal
The price is $116 per night from Feb 24 to Feb 25
$116
includes taxes & fees
Feb 24 - Feb 25
Stay at this 3-star hotel in Chicago. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (2,956 reviews)
"Good place"

Reviewed on Feb 18, 2025

Hilton Garden Inn Chicago Downtown/Magnificent Mile
Wyndham New Orleans - French Quarter
Wyndham New Orleans - French Quarter
4 out of 5
124 Royal St, New Orleans, LA
The price is $138 per night from Feb 24 to Feb 25
$138
includes taxes & fees
Feb 24 - Feb 25
Book a stay at this business-friendly hotel in New Orleans. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.4/10 Very Good! (3,551 reviews)
"Hotel is in a good location for visiting the French Quarter. Rooms are decent and fairly clean. In my room the bath tile walls hadn't been cleaned recently and the headboards did not look very clean at all. Like they had been wiped with dirty rags or something. Also the room heat/ac unit was pretty ..."

Reviewed on Feb 20, 2025

Wyndham New Orleans - French Quarter
Gaylord Opryland Resort & Convention Center
Gaylord Opryland Resort & Convention Center
4 out of 5
2800 Opryland Drive, Nashville, TN
  • 19 hours drive from Port of Galveston Cruise Terminal
The price is $473 per night from Feb 23 to Feb 24
$473
includes taxes & fees
Feb 23 - Feb 24
Stay at this 4-star spa resort in Nashville. Enjoy 2 outdoor pools, a full-service spa, and 18 restaurants. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,630 reviews)
"The place is amazing and they have people standing around to help you if you need it which we did which was super helpful. Mexican restaurant food was not good. Room was great but the pillows gave me neck pain. The shower is awesome, the water pressure being great. The bath products smelled so good ..."

Reviewed on Feb 19, 2025

Gaylord Opryland Resort & Convention Center
Bourbon Orleans Hotel
Bourbon Orleans Hotel
4 out of 5
717 Orleans St., New Orleans, LA
The price is $192 per night from Feb 24 to Feb 25
$192
includes taxes & fees
Feb 24 - Feb 25
Book a stay at this historic hotel in New Orleans. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the pool and the bar in our ...
8.8/10 Excellent! (3,525 reviews)
"The staff were very friendly.The breakfast was cold when we waited and was told they cook each order so there was a 20min wait."

Reviewed on Feb 20, 2025

Bourbon Orleans Hotel
Crowne Plaza New Orleans French Qtr - Astor
Crowne Plaza New Orleans French Qtr - Astor
4.5 out of 5
739 Canal Street at Bourbon, New Orleans, LA
The price is $115 per night from Mar 9 to Mar 10
$115
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4.5-star luxury hotel in New Orleans. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the helpful ...
7.4/10 Good! (3,961 reviews)
Street of horrors.
"Adequate hotel. Good for an overnight, great location and good value. Parking valet is ia nightmare. valets have no idea of costs, service and are happy to leave you waiting forever on the street. I would seek another hotel."

Reviewed on Feb 19, 2025

Crowne Plaza New Orleans French Qtr - Astor
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4 out of 5
5353 Westheimer Rd, Houston, TX
  • 1 hour drive from Port of Galveston Cruise Terminal
The price is $143 per night from Mar 23 to Mar 24
$143
includes taxes & fees
Mar 23 - Mar 24
Stay at this hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,768 reviews)
"26 floor room views were amazing"

Reviewed on Feb 20, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Comfort Inn Downtown Nashville - Music City Center
Comfort Inn Downtown Nashville - Music City Center
3 out of 5
1501 Demonbreun St, Nashville, TN
  • 19 hours drive from Port of Galveston Cruise Terminal
The price is $107 per night from Feb 23 to Feb 24
$107
includes taxes & fees
Feb 23 - Feb 24
Stay at this 3-star business-friendly hotel in Nashville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the pool ...
8/10 Very Good! (1,717 reviews)
"Hotel was fine. Nothing special, but fine for a couple night's stay."

Reviewed on Feb 20, 2025

Comfort Inn Downtown Nashville - Music City Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central United States

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central United States.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central United States’s 283,050 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $103. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central United States hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central United States. No matter your reason for visiting Central United States, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central United States hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central United States for as low as $103.

How many hotels are there in Central United States?

With over 283,050 hotels in Central United States, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $103.

How to find cheap car rentals in Central United States?

Finding a cheap car rental deal in Central United States is as easy as scoring cheap hotels in Central United States. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.