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Choose from 122 Rome Hotel Deals

1 Mi to Hunting: Cozy & Secluded Stout Cabin

1 Mi to Hunting: Cozy & Secluded Stout Cabin

3 out of 5
Rome
  • 4 hours drive from Ohio River Valley
Stay at this 3-star cottage in Rome. Enjoy free parking.
1 Mi to Hunting: Cozy & Secluded Stout Cabin
Stout Cabin w/ Fire Pit: 1 Mi to Ohio River!

Stout Cabin w/ Fire Pit: 1 Mi to Ohio River!

3 out of 5
Rome
  • 4 hours drive from Ohio River Valley
Stay at this 3-star cottage in Rome. Enjoy free parking and air conditioning.
Stout Cabin w/ Fire Pit: 1 Mi to Ohio River!
Super 8 by Wyndham Portsmouth

Super 8 by Wyndham Portsmouth

2 out of 5
4266 US Route 23 N, Portsmouth, OH
  • 4 hours drive from Ohio River Valley
Book a stay at this business-friendly motel in Portsmouth. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (656 reviews)
"I had a room on the second floor and there were children above me running back and forth on the floor above me. Also, I requested a late check-out, was appproved, and paid the extra fee. However, it wasn't communicated with the morning staff or put in their notes. They began knocking on my door at ..."

Reviewed on Oct 5, 2025

Super 8 by Wyndham Portsmouth
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
5100 Old Scioto Trail, Portsmouth, OH
  • 4 hours drive from Ohio River Valley
Book a stay at this business-friendly hotel in Portsmouth. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (546 reviews)
"Didn't have it"

Reviewed on Sep 26, 2025

Quality Inn & Suites
Beverly hills inn

Beverly hills inn

2.5 out of 5
1830 U.S. 52, Aberdeen, OH
  • 3 hours drive from Ohio River Valley
Book a stay at this business-friendly hotel in Aberdeen. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Old Pogue Distillery and Kentucky ...
8.6/10 Excellent! (131 reviews)
"The staff is amazing"

Reviewed on Oct 13, 2025

Beverly hills inn
Holiday Inn Portsmouth Downtown by IHG

Holiday Inn Portsmouth Downtown by IHG

3 out of 5
711 2nd St, Portsmouth, OH
  • 4 hours drive from Ohio River Valley
Stay at this 3-star business-friendly hotel in Portsmouth. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.4/10 Very Good! (449 reviews)
"Wish there was a dirty clothes bag"

Reviewed on Oct 12, 2025

Holiday Inn Portsmouth Downtown by IHG
Four Keys Inn

Four Keys Inn

2 out of 5
2302 Scioto Trail /2852, Portsmouth, OH
  • 4 hours drive from Ohio River Valley
Stay at this motel in Portsmouth. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Mound Park and Boneyfiddle Commercial District are located ...
6.2/10 (100 reviews)
Home away from home
"Owner is so sweet and understanding."

Reviewed on Jul 26, 2025

Four Keys Inn
Days Inn by Wyndham Maysville Kentucky

Days Inn by Wyndham Maysville Kentucky

2.5 out of 5
484 Moody Dr, Maysville, KY
  • 3 hours drive from Ohio River Valley
Book a stay at this business-friendly hotel in Maysville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (377 reviews)
"The rooms haven’t been updated in a while, but they are very clean and comfortable. The check in process was easy and the front desk attendant was friendly. Overall a nice place to stay for a night."

Reviewed on Sep 30, 2025

Days Inn by Wyndham Maysville Kentucky
Quality Inn

Quality Inn

2.5 out of 5
8226 Ohio River Rd, Wheelersburg, OH
  • 4 hours drive from Ohio River Valley
Book a stay at this business-friendly hotel in Wheelersburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (298 reviews)
"It’s a very nice place. I’d stay there again."

Reviewed on Oct 5, 2025

Quality Inn
Country Nights Inn

Country Nights Inn

2.5 out of 5
11255 State Rte 41, West Union, OH
  • 3 hours drive from Ohio River Valley
Stay at this motel in West Union. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Adams Lake State Park is located nearby.
7.8/10 Good! (38 reviews)
"The room was clean. Staff was friendly."

Reviewed on Oct 3, 2025

Country Nights Inn
Red Roof Inn Wheelersburg

Red Roof Inn Wheelersburg

2 out of 5
8340 Ohio River Road, Wheelersburg, OH
  • 4 hours drive from Ohio River Valley
Book a stay at this business-friendly hotel in Wheelersburg. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Wheelersburg Golf Range is ...
7/10 Good! (285 reviews)
"was very nice"

Reviewed on Oct 10, 2025

Red Roof Inn Wheelersburg
Brown's Motel Aberdeen

Brown's Motel Aberdeen

2 out of 5
1055 US HWY 52, Aberdeen, OH
  • 3 hours drive from Ohio River Valley
Stay at this motel in Aberdeen. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Kentucky Gateway Museum Center and Old Pogue Distillery ...
7.4/10 Good! (252 reviews)
"Rooms are clean water is hot and plentiful and the staff friendly."

Reviewed on Sep 22, 2025

Brown's Motel Aberdeen
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Rome

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $53. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Rome hotel deals at the last minute.

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Frequently Asked Questions About Rome hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Rome for as low as $53.

How many hotels are there in Rome?

With over 122 hotels in Rome, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $53.

How to find cheap car rentals in Rome?

Finding a cheap car rental deal in Rome is as easy as scoring cheap hotels in Rome. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.