Search for Cheap Deals on
Hotels in Roxboro

Choose from 363 Roxboro Hotel Deals

Quality Inn - Roxboro South

Quality Inn - Roxboro South

2.5 out of 5
906 Durham Road Roxboro NC
  • 26 min drive from Mayo Lake
Stay at this hotel in Roxboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Barden ...
7.6/10 Good! (479 reviews)
"Too many stairs to 2nd floor if you are handicapped. A lot of truckers"

Reviewed on Jun 20, 2026

Quality Inn - Roxboro South
Hampton Inn Roxboro

Hampton Inn Roxboro

2.5 out of 5
920 Durham Rd Roxboro NC
  • 26 min drive from Mayo Lake
Book a stay at this business-friendly hotel in Roxboro. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Barden St Park and Kirby Cultural ...
9/10 Wonderful! (355 reviews)
"Great day, on last evening June 12,2026, I woke to an itchy feeling on my back, arms and legs. I immediately got up. I pulled the cover back. I then pulled the cover back and seen the first bedbug not sure at the time what it was I smashed it , making a red bloody mark. I began moving the pillow ..."

Reviewed on Jun 13, 2026

Hampton Inn Roxboro
Budget Inn Roxboro

Budget Inn Roxboro

2 out of 5
1033 N Madison Blvd Roxboro NC
  • 21 min drive from Mayo Lake
Book a stay at this business-friendly motel in Roxboro. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Person County Museum and Kirby ...
6.4/10 (173 reviews)
"The place is running down and looks line homeless people live there. Do NOT book."

Reviewed on Jun 28, 2026

Budget Inn Roxboro
Americas Best Value Inn Roxboro

Americas Best Value Inn Roxboro

2 out of 5
1006 North Madison Boulevard Roxboro NC
  • 21 min drive from Mayo Lake
Stay at this motel in Roxboro. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Person County Museum and Kirby Cultural Arts Complex are ...
6.6/10 (91 reviews)
"Someone should have notified incoming visitors of roof construction…"

Reviewed on May 30, 2026

Americas Best Value Inn Roxboro
Hilton Durham near Duke University

Hilton Durham near Duke University

3.5 out of 5
3800 Hillsborough Rd Durham NC
  • 1 hour drive from Mayo Lake
Book a stay at this business-friendly hotel in Durham. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,008 reviews)
"Bathroom is very small to take shower and it is so much clean."

Reviewed on Jul 2, 2026

Hilton Durham near Duke University
Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

2.5 out of 5
1816 Hillandale Rd Durham NC
  • 1 hour drive from Mayo Lake
Book a stay at this business-friendly hotel in Durham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,053 reviews)
"Breakfast was good."

Reviewed on Jul 1, 2026

Comfort Inn & Suites Durham near Duke University
Courtyard Durham Near Duke University/Downtown

Courtyard Durham Near Duke University/Downtown

3 out of 5
1815 Front St Durham NC
  • 1 hour drive from Mayo Lake
Book a stay at this golf hotel in Durham. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our ...
8.2/10 Very Good! (1,001 reviews)
"I had a great stay.Hotel was nice and convenient. Very close to the highway. Staff was great."

Reviewed on Jul 2, 2026

Courtyard Durham Near Duke University/Downtown
The Bee Hotel Danville

The Bee Hotel Danville

2.5 out of 5
420 Patton St Danville VA
  • 37 min drive from Mayo Lake
Stay at this hotel in Danville. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (634 reviews)
"Loved the history of the building. Staff was super friendly and helpful."

Reviewed on Jul 2, 2026

The Bee Hotel Danville
Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center

2 out of 5
1915 N Pointe Drive Durham NC
  • 1 hour drive from Mayo Lake
Stay at this hotel in Durham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.8/10 (1,001 reviews)
"We stay at this property pretty often.. Just wish the showers and the floors were a little bit cleaner.. but other than that it's a good place to stay.."

Reviewed on Jun 21, 2026

Red Roof Inn Durham - Duke Univ Medical Center
Sleep Inn & Suites Danville Hwy 58

Sleep Inn & Suites Danville Hwy 58

2.5 out of 5
1483 S Boston Rd Danville VA
  • 33 min drive from Mayo Lake
Book a stay at this business-friendly hotel in Danville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (807 reviews)
"Friendly staff, roomsnest and clean"

Reviewed on Jun 29, 2026

Sleep Inn & Suites Danville Hwy 58
OYO Hotel Durham West Hills

OYO Hotel Durham West Hills

2.5 out of 5
3220 Kuber Blvd Durham NC
  • 1 hour drive from Mayo Lake
Stay at this hotel in Durham. Enjoy free parking, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in our ...
7/10 Good! (796 reviews)
"They couldn’t find my reservation. Then put me into a smokers room, the tables had holes in them, the lampshades were all broken, the blankets and pillows smelled like strong smoking odor. I’m allergic to smoke. It took hours for the air conditioner to get cool and several minutes for shower to get ..."

Reviewed on Jun 29, 2026

OYO Hotel Durham West Hills
The Berry Hill Resort & Conference Center

The Berry Hill Resort & Conference Center

4 out of 5
3105 River Road South Boston VA
  • 29 min drive from Mayo Lake
Book a stay at this spa hotel in South Boston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (747 reviews)
"when i arrived and was given a room key the room was a total mess and had not been cleaned at all from the previous day. this was a check in after 3pm. Housekeeping had marked the room as clean. Lobby clerk very apologetic and nice. the next room looked clean but had a wad of hair on the floor in ..."

Reviewed on Jul 2, 2026

The Berry Hill Resort & Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Roxboro

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Roxboro hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Roxboro.

Choosing the right hotel in North Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Roxboro’s 363 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $65. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Roxboro hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Roxboro. No matter your reason for visiting Roxboro, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Roxboro hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Roxboro for as low as $65.

How many hotels are there in Roxboro?

With over 363 hotels in Roxboro, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $65.

How to find cheap car rentals in Roxboro?

Finding a cheap car rental deal in Roxboro is as easy as scoring cheap hotels in Roxboro. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.