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Santa Cruz Island Vacation Packages

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Santa Cruz Island
Galápagos
Ecuador
South America
Hotwire.com

Santa Cruz Island Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Galapagos Native

3 out of 5

Price was $841, price is now $611 per person

$611

per person

Sep 30 - Oct 4

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Book a stay at this spa guesthouse in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Fishing Piers and Gus Angermeyer Ferry Terminal are located nearby.

BAY VIEW HOUSE

3.5 out of 5

Price was $981, price is now $670 per person

$670

per person

Sep 30 - Oct 4

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Book a stay at this spa guesthouse in Puerto Ayora. Enjoy free WiFi, a full-service spa, and daily housekeeping. Popular attractions Gus Angermeyer Ferry Terminal and Malecon are located nearby.

Ikala Galapagos Hotel

4 out of 5

Price was $1,140, price is now $883 per person

$883

per person

Sep 30 - Oct 4

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Book a stay at this business-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Tortuga Bay Beach and Malecon are located nearby.

Breakfast was fantastic. Staff was friendly and helpful in recommending things to do and setting up transportation for us. Beds were comfortable.

Reviewed on Jun 29, 2026

Natura Gardens Galápagos Hotel

3 out of 5

Price was $877, price is now $681 per person

$681

per person

Sep 30 - Oct 4

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Stay at this hotel in Bella Vista. Enjoy free breakfast, onsite spa services, and daily housekeeping. Popular attractions Tortuga Bay Beach and Charles Darwin Research Station are located nearby.

Royal Palm Galapagos, Curio Collection Hotel by Hilton

4.5 out of 5

Price was $1,872, price is now $1,498 per person

$1,498

per person

Sep 30 - Oct 4

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Book a stay at this luxury hotel in Santa Rosa. Enjoy free WiFi, an outdoor pool, and 2 restaurants. Popular attractions Los Gemelos Sinkholes and Lava Tunnel are located nearby.

Truly spectacular. The rooms were beyond gorgeous. The property is pristine and the staff was so attentive. Highly recommend the lava tunnel dinner. It was amazing.

Reviewed on Jul 20, 2026

Angermeyer Waterfront Inn

3.5 out of 5

Price was $1,084, price is now $873 per person

$873

per person

Sep 30 - Oct 4

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Stay at this hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a marina. Our guests praise the helpful staff in our reviews. Popular attractions Playa de los Alemanes and Malecon are located nearby.

Nicest place I’ve ever stayed. Staff greeted you with drinks, cold towel, and ac. Beautiful on water. Also next door had best pina colada I’ve ever had !

Reviewed on Jun 29, 2026

Hotel el descanso del Guia

3.5 out of 5

Price was $797, price is now $648 per person

$648

per person

Sep 30 - Oct 4

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions Tortuga Bay Beach and Las Ninfas Lagoon are located nearby.

Reviewed on Jul 25, 2026

Finch Bay Galapagos Hotel

4.5 out of 5

Price was $1,943, price is now $1,589 per person

$1,589

per person

Sep 30 - Oct 4

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Book a stay at this luxury hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Tortuga Bay Beach and Playa de los Alemanes are located nearby.

The staff and service are exceptional! The venue cannot be beaten. It’s the only place with a private beach. They have complementary water taxis that take you everywhere. When we got off our boat, they were waiting for us without us, even having to notify them. Definitely would recommend this hotel again.

Reviewed on Jul 4, 2026