Search Cheap Flights to
Santa Cruz Island

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Santa Cruz Island Flights as Low as $275

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
avianca

Cheap Flights to Santa Cruz Island

Fall in love at first flight with your vacation to Santa Cruz Island by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz Island on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz Island, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Cruz Island

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz Island with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GPS airport.

What is the cheapest month to fly to Santa Cruz Island?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz Island are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz Island?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Cruz Island.

What airport is best to fly into Santa Cruz Island?

When you’re planning your trip to Santa Cruz Island, convenience is the name of the game. Luckily, Santa Cruz Island Seymour Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz Island must-do list.

How much are flights to Santa Cruz Island?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz Island on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $275, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz Island?

The trick to saving a stack of cash on your flight to Santa Cruz Island? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $275 right now, why wait?

Santa Cruz Island Flight Information
Destination airport
Seymour
Destination airport IATA code
GPS
Roundtrip price
$274

Last Minute Hotel Deals in Santa Cruz Island

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Stay at this hotel in Puerto Ayora. Enjoy free WiFi, 3 hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Las ...
9/10 Wonderful! (388 reviews)
This is a small, friendly hotel, well maintained and a modern pool area. It is located in a quiet road just a 10 min walk from the harbour and restaurants. Breakfast was a bit limited.

Reviewed on Jan 11, 2026

Hotel Fiesta
Ikala Galapagos Hotel

Ikala Galapagos Hotel

4 out of 5
Tomas de Berlanga 110 y Moises Brito Puerto Ayora Ecuador
Book a stay at this business-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff and ...
9.6/10 Exceptional! (131 reviews)
Gorgeous property and wonderful staff!

Reviewed on Jan 24, 2026

Ikala Galapagos Hotel
Maidith Galapagos Inn

Maidith Galapagos Inn

3 out of 5
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast and the helpful ...
9.8/10 Exceptional! (107 reviews)
Great place! Incredibly friendly and kind staff.

Reviewed on Jan 8, 2026

Maidith Galapagos Inn
El Barranco Galapagos

El Barranco Galapagos

2.5 out of 5
Los colonos Puerto Ayora Galapagos
Stay at this hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and room service. Popular attractions Malecon and Gus Angermeyer Ferry Terminal are located ...
9.6/10 Exceptional! (37 reviews)
Great location, nice sea view on balcony, rooms clean and spacious. Breakfast was good especially the omelette

Reviewed on Jan 15, 2026

El Barranco Galapagos
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

4.5 out of 5
Barrio Punta Estrada Puerto Ayora Galapagos
Book a stay at this luxury hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Playa de los Alemanes and Malecon ...
9.2/10 Wonderful! (92 reviews)
The staff couldn’t have done more for us the hotel was stunning. Five star throughout. It’s expensive but so worth it

Reviewed on Jan 8, 2026

Finch Bay Galapagos Hotel
Capitan Max B&B

Capitan Max B&B

3 out of 5
Charles Binford St Puerto Ayora Galapagos
Book a stay at this business-friendly B&B in Puerto Ayora. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (207 reviews)
Excelente ubicación Muy limpio

Reviewed on Jan 20, 2026

Capitan Max B&B
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our ...
8.6/10 Excellent! (184 reviews)
The staff were helpful, friendly and caring. Breakfast was just right, we definitely made use of that amenity. The rooms were very basic but must say very clean with good enough space for our family.

Reviewed on Jan 20, 2026

Hotel el descanso del Guia
Galapagos Dreams

Galapagos Dreams

3 out of 5
Av. Cucuve y Floreana Puerto Ayora Santa Cruz
Book a stay at this spa hostal in Puerto Ayora. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (124 reviews)
The whole team did an amazing job, and special shout out to Andy who went above and beyond to provide the best service. Jonatan has an incredible team and they made this one of the best experiences even when things did not go as planned. They were able to accommodate as much as possible in a short ...

Reviewed on Aug 30, 2025

Galapagos Dreams
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.