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Santa Cruz Island

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Santa Cruz Island Flights as Low as $1,558

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

United
Sat, Aug 16 - Fri, Aug 22
DEN
Denver Intl.
GPS
Seymour
$1,558 Roundtrip, found 4 days ago
$1,558
Roundtrip
found 4 days ago
Select United flight, departing Sat, Aug 16 from Denver Intl. to Seymour, returning Fri, Aug 22, priced at $1,558 found 4 days ago
United
Sat, Aug 16 - Wed, Aug 20
DEN
Denver Intl.
GPS
Seymour
$1,594 Roundtrip, found 3 days ago
$1,594
Roundtrip
found 3 days ago
Select United flight, departing Sat, Aug 16 from Denver Intl. to Seymour, returning Wed, Aug 20, priced at $1,594 found 3 days ago
LATAM Airlines Group
Fri, Aug 15 - Fri, Aug 22
DEN
Denver Intl.
GPS
Seymour
$1,718 Roundtrip, found 3 days ago
$1,718
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Fri, Aug 15 from Denver Intl. to Seymour, returning Fri, Aug 22, priced at $1,718 found 3 days ago
LATAM Airlines Group
Fri, Aug 15 - Fri, Aug 22
DEN
Denver Intl.
GPS
Seymour
$1,728 Roundtrip, found 3 days ago
$1,728
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Fri, Aug 15 from Denver Intl. to Seymour, returning Fri, Aug 22, priced at $1,728 found 3 days ago
United
Sat, Aug 16 - Wed, Aug 20
DEN
Denver Intl.
GPS
Seymour
$1,746 Roundtrip, found 3 days ago
$1,746
Roundtrip
found 3 days ago
Select United flight, departing Sat, Aug 16 from Denver Intl. to Seymour, returning Wed, Aug 20, priced at $1,746 found 3 days ago
JetBlue Airways
Sat, Aug 16 - Fri, Aug 22
DEN
Denver Intl.
GPS
Seymour
$1,863 Roundtrip, found 4 days ago
$1,863
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Sat, Aug 16 from Denver Intl. to Seymour, returning Fri, Aug 22, priced at $1,863 found 4 days ago
JetBlue Airways
Sat, Aug 16 - Fri, Aug 22
DEN
Denver Intl.
GPS
Seymour
$1,867 Roundtrip, found 4 days ago
$1,867
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Sat, Aug 16 from Denver Intl. to Seymour, returning Fri, Aug 22, priced at $1,867 found 4 days ago
JetBlue Airways
Wed, Aug 13 - Thu, Aug 21
DEN
Denver Intl.
GPS
Seymour
$1,886 Roundtrip, found 3 days ago
$1,886
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Aug 13 from Denver Intl. to Seymour, returning Thu, Aug 21, priced at $1,886 found 3 days ago
JetBlue Airways
Tue, Aug 12 - Thu, Aug 21
DEN
Denver Intl.
GPS
Seymour
$1,886 Roundtrip, found 4 days ago
$1,886
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Tue, Aug 12 from Denver Intl. to Seymour, returning Thu, Aug 21, priced at $1,886 found 4 days ago
United
Wed, Aug 13 - Thu, Aug 21
DEN
Denver Intl.
GPS
Seymour
$1,898 Roundtrip, found 3 days ago
$1,898
Roundtrip
found 3 days ago
Select United flight, departing Wed, Aug 13 from Denver Intl. to Seymour, returning Thu, Aug 21, priced at $1,898 found 3 days ago
JetBlue Airways
Wed, Aug 13 - Thu, Aug 21
DEN
Denver Intl.
GPS
Seymour
$1,904 Roundtrip, found 3 days ago
$1,904
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Aug 13 from Denver Intl. to Seymour, returning Thu, Aug 21, priced at $1,904 found 3 days ago
JetBlue Airways
Fri, Aug 15 - Fri, Aug 22
DEN
Denver Intl.
GPS
Seymour
$1,915 Roundtrip, found 3 days ago
$1,915
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Fri, Aug 15 from Denver Intl. to Seymour, returning Fri, Aug 22, priced at $1,915 found 3 days ago
JetBlue Airways
Sat, Aug 16 - Fri, Aug 22
DEN
Denver Intl.
GPS
Seymour
$1,917 Roundtrip, found 4 days ago
$1,917
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Sat, Aug 16 from Denver Intl. to Seymour, returning Fri, Aug 22, priced at $1,917 found 4 days ago
JetBlue Airways
Thu, Aug 14 - Fri, Aug 22
DEN
Denver Intl.
GPS
Seymour
$1,931 Roundtrip, found 4 days ago
$1,931
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Thu, Aug 14 from Denver Intl. to Seymour, returning Fri, Aug 22, priced at $1,931 found 4 days ago
JetBlue Airways
Tue, Aug 12 - Thu, Aug 21
DEN
Denver Intl.
GPS
Seymour
$1,933 Roundtrip, found 5 days ago
$1,933
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Tue, Aug 12 from Denver Intl. to Seymour, returning Thu, Aug 21, priced at $1,933 found 5 days ago
Air Europa
Fri, Apr 10 - Mon, Apr 13
ZRH
Zürich
GPS
Seymour
$2,320 Roundtrip, found 1 day ago
$2,320
Roundtrip
found 1 day ago
Select Air Europa flight, departing Fri, Apr 10 from Zürich to Seymour, returning Mon, Apr 13, priced at $2,320 found 1 day ago

Cheap Flights to Santa Cruz Island

Fall in love at first flight with your vacation to Santa Cruz Island by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz Island on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz Island, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Cruz Island

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz Island with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GPS airport.

What is the cheapest month to fly to Santa Cruz Island?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz Island are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz Island?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Cruz Island.

What airport is best to fly into Santa Cruz Island?

When you’re planning your trip to Santa Cruz Island, convenience is the name of the game. Luckily, Santa Cruz Island Seymour Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz Island must-do list.

How much are flights to Santa Cruz Island?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz Island on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $1,558, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz Island?

The trick to saving a stack of cash on your flight to Santa Cruz Island? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $1,558 right now, why wait?

Santa Cruz Island Flight Information
Destination airport
Seymour
Destination airport IATA code
GPS
Roundtrip price
$1,557

Last Minute Hotel Deals in Santa Cruz Island

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo, Puerto Ayora, Galapagos
Stay at this 3.5-star hotel in Puerto Ayora. Enjoy free WiFi, 3 hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (351 reviews)
Helpful Staff and Great Location
"The staff was very helpful and the hotel was in a safe and quiet location. The pool was cold but nice and the pillows were some of the most comfortable I’ve ever slept on."

Reviewed on Jul 25, 2025

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Hotel Fiesta
El Barranco Galapagos

El Barranco Galapagos

2.5 out of 5
Los colonos, Puerto Ayora, Galapagos
Stay at this hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and room service. Popular attractions Malecon and Gus Angermeyer Ferry Terminal are located ...
9.2/10 Wonderful! (10 reviews)
"amazing hotel and the best service the pool is the perfect spot to see seals, sea turtles, sting rays, sharks and pelicans , at night it’s quiet and the room was perfect. loved especially my balcony overlooking the docks."

Reviewed on Jul 6, 2025

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El Barranco Galapagos
Hotel Cucuve

Hotel Cucuve

4 out of 5
Charles Binford 083 y Ave Charles Darwin, Puerto Ayora
Stay at this 4-star B&B in Puerto Ayora. Enjoy free breakfast, free WiFi, and an airport shuttle (surcharge). Our guests praise the breakfast and the helpful ...
9.8/10 Exceptional! (255 reviews)
"Excellent"

Reviewed on Jul 22, 2025

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Hotel Cucuve
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador, Puerto Ayora, Galapagos
Stay at this 3.5-star family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our ...
8.6/10 Excellent! (159 reviews)
"I only leave a 4 star review because I stayed for 5 days and the breakfasts were boring. Every day they offered the same thing, eggs, toast, or pancakes, cereal and strawberry yogurt. They don’t have a restaurant in the hotel and everything is far away. After the second day I was bored with the breakfast ..."

Reviewed on Jun 29, 2025

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Hotel el descanso del Guia
Royal Palm Galapagos, Curio Collection Hotel by Hilton

Royal Palm Galapagos, Curio Collection Hotel by Hilton

4.5 out of 5
Km. 18 Via Puerto Ayora-Baltra Isla, Isla Santa Cruz, Santa Rosa, Galapagos
Stay at this 4.5-star luxury hotel in Santa Rosa. Enjoy free WiFi, an outdoor pool, and 2 restaurants. Popular attractions Los Gemelos Sinkholes and Lava Tunnel ...
9.2/10 Wonderful! (49 reviews)
"The Royal Palm offers a truly immersive Galápagos experience—set inland on a stunning 100 acre property, far from the touristy feel of the ports. Recently under new ownership, the property is being refreshed: rooms are spacious and renovated, the pool has been redone, and quiet renovations are underway, ..."

Reviewed on Apr 20, 2025

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Royal Palm Galapagos, Curio Collection Hotel by Hilton
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

4.5 out of 5
Barrio Punta Estrada, Puerto Ayora, Galapagos
Stay at this 4.5-star luxury hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Playa de los Alemanes and Malecon ...
9.2/10 Wonderful! (86 reviews)
"Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!"

Reviewed on Dec 31, 2024

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Finch Bay Galapagos Hotel
Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge

4 out of 5
Ave. Charles Darwin S/n Y Piquero, Puerto Ayora, Galapagos
Stay at this 4-star business-friendly hotel in Puerto Ayora. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in ...
8.8/10 Excellent! (113 reviews)
"Wonderful hotel. Our room was incredible. We stayed in Darwin. But there was no hot water for 2/3 of our stay. All we were able to get out of them was a free breakfast one day. I would have expected a significant discount given this lacking amenity"

Reviewed on May 27, 2025

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Blu Galapagos Sustainable Waterfront Lodge
Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

3.5 out of 5
Punta Estrada, Isla Santa Cruz, Puerto Ayora, Galapagos
Stay at this 3.5-star hotel in Puerto Ayora. Enjoy free WiFi, a marina, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (118 reviews)
"Staff was very friendly and professional. They helped us with everything we asked for."

Reviewed on Jul 4, 2025

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Angermeyer Waterfront Inn
See all 202 properties in Santa Cruz Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.