Hotels Near
Santo Spirito

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured Santo Spirito Hotels

UNAHOTELS Vittoria Firenze
UNAHOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (985 reviews)
"Reception"

Reviewed on Nov 13, 2024

UNAHOTELS Vittoria Firenze
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (462 reviews)
AMAZING!!
"Amaizing experience! The amenities were extremely neat, food and drinks were great and the staff was outstanding!!! Overall 15/10 on the experience. I would definitely stay again!"

Reviewed on Dec 13, 2024

Hotel Horto Convento
Palazzo Oliveto
Palazzo Oliveto
Via Monte Oliveto, 32, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and a garden. Popular attractions Historic Centre of Florence and Pitti Palace are located ...
7.2/10 Good! (51 reviews)
"Owner is very responsive and approachable. Very clean and quiet place,definitely will recommend to friends and relatives."

Reviewed on Nov 22, 2024

Palazzo Oliveto
Foresteria Valdese di Firenze - Casa per Ferie
Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49, Florence
Fully refundableReserve now, pay when you stay
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.6/10 Excellent! (107 reviews)
"Our room was large, and the staff was friendly and helpful. It is a quick walk over the bridge to the heart of Florence, and there are many good dining options nearby."

Reviewed on Oct 31, 2024

Foresteria Valdese di Firenze - Casa per Ferie
Hostel Santa Monaca
Hostel Santa Monaca
Via Santa Monaca 6, Florence, FI
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and dry cleaning or laundry services. Popular attractions Historic Centre of Florence and ...
8/10 Very Good! (49 reviews)
"The reviews told me the chances of getting bed bugs was likely. I did get bed bugs. And am now attempting to deal with this which continuing to travel. The actual place was okay but they need to fumigated. If you are ok with bedbugs it’s an okay place. Otherwise. Be warned. Also. The staff were not ..."

Reviewed on May 29, 2024

Hostel Santa Monaca
1900 Artevita
1900 Artevita
Viale Raffaello Sanzio 2, Florence, FI
Stay at this B&B in Florence. Enjoy free WiFi, breakfast (surcharge), and housekeeping. Popular attractions Historic Centre of Florence and Pitti Palace are ...
8.6/10 Excellent! (159 reviews)
"Excellent stay - easy walk to centre - highly recommended"

Reviewed on Nov 1, 2024

1900 Artevita
Casa Santo Nome di Gesù
Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence
Fully refundableReserve now, pay when you stay
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (263 reviews)
"Everything was ok. Thank you."

Reviewed on Nov 2, 2024

Casa Santo Nome di Gesù
La Torre Del Cestello
La Torre Del Cestello
Via Borgo San Frediano, 8, Florence
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Historic Centre of Florence and Pitti ...
8.8/10 Excellent! (163 reviews)
"Excellent location Friendly people and supportive"

Reviewed on Dec 9, 2024

La Torre Del Cestello
Hotel Palazzo Guadagni
Hotel Palazzo Guadagni
3 out of 5
Piazza Santo Spirito 9, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Popular attractions Historic Centre of ...
9/10 Wonderful! (185 reviews)
"The Hotel is so charming and exactly the vibe you want from Florence. The staff are amazing and they are very helpful guides to the city and have great, chic taste."

Reviewed on Dec 19, 2024

Hotel Palazzo Guadagni
Drom Florence Rooms & Apartments
Drom Florence Rooms & Apartments
Via dei Serragli 137, Florence, FI
Stay at this guesthouse in Florence. Enjoy free WiFi, a garden, and premium bedding. Our guests praise the property condition in our reviews. Popular attractions ...
9.6/10 Exceptional! (105 reviews)
"I stayed at Drom Florence for five days in November 2024 and loved everything about it. The room was spotless, spacious and well appointed, with a stocked beverage fridge and traditional decor. Claudia and Antonio were amazing hosts and communicated regularly about my stay to ensure I always had ..."

Reviewed on Nov 25, 2024

Drom Florence Rooms & Apartments
Oltrarno Splendid
Oltrarno Splendid
Via dei Serragli 7, Florence, Città Metropolitana di Firenze
Fully refundableReserve now, pay when you stay
Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.8/10 Exceptional! (75 reviews)
"quiet -staff great"

Reviewed on Nov 18, 2024

Oltrarno Splendid
Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (941 reviews)
"Hotel is located within walking distance to all attractions. Restaurants and grocery stores are nearby. There’s a small kitchen inside the unit to cook simple meals which is a plus."

Reviewed on Oct 24, 2024

Palazzo Mannaioni Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santo Spirito

Florence is a city that has a lot going on, but you have your sights set on Santo Spirito. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santo Spirito has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santo Spirito hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Florence so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santo Spirito underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santo Spirito city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santo Spirito cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santo Spirito at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $67
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santo Spirito hotel you want, book it, and never look back. Because your great escape is ahead of you.