Hotels Near
Santo Spirito

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Tonight Mar 23 - Mar 24Next weekend Mar 28 - Mar 30

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Featured Santo Spirito Hotels

Foresteria Valdese di Firenze - Casa per Ferie
Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.6/10 Excellent! (115 reviews)
"Our room was large, and the staff was friendly and helpful. It is a quick walk over the bridge to the heart of Florence, and there are many good dining options nearby."

Reviewed on Oct 31, 2024

Foresteria Valdese di Firenze - Casa per Ferie
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (494 reviews)
Wonderful hotel would stay again.
"We stayed for two nights. The staff was helpful and very friendly. Giovani gave us a great welcome and notes on places to visit. The room was beautiful and the amenities plentiful. The view was great and the huge window was spectacular. The breakfast was so good with hot and cold options. The staff ..."

Reviewed on Mar 15, 2025

Hotel Horto Convento
Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (957 reviews)
"This is a very nice place to stay. Very clean and modern. The rainfall shower in our bathroom was nice, and the beds were comfortable. The only complaint was the noise outside every night."

Reviewed on Mar 9, 2025

Palazzo Mannaioni Suites
UNA HOTELS Vittoria Firenze
UNA HOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (985 reviews)
"Was checked in by a lovely lady who made us aware of our VIP status and amenities with it. The hotel was kind enough to hold our luggage when we checked out so we could explore before heading to the train station. They were also kind enough to ask about arranging a taxi for pick up to take us to ..."

Reviewed on Dec 31, 2024

UNA HOTELS Vittoria Firenze
Casa Santo Nome di Gesù
Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (270 reviews)
Loved Florence.
"Great location, friendly staff, great breakfast, peaceful backyard, and compelling hiatorical site."

Reviewed on Mar 19, 2025

Casa Santo Nome di Gesù
Palazzo Oliveto
Palazzo Oliveto
Via Monte Oliveto, 32, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and a garden. Popular attractions Historic Centre of Florence and Uffizi Gallery are located ...
7.6/10 Good! (60 reviews)
Good location
"I like the location of the hotel. Not too far from the centre. There are bus station next to the hotel which you can easily reach the duomo and plaza michiangelo. The breakfast is in the breakfast room everyday morning, the lady preparing the breakfast was really kind and friendly."

Reviewed on Mar 17, 2025

Palazzo Oliveto
AdAstra Suites
AdAstra Suites
Via Del Campuccio, 53, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (194 reviews)
"Beautiful property! Excellent dining options."

Reviewed on Jan 18, 2025

AdAstra Suites
La Torre Del Cestello
La Torre Del Cestello
Via Borgo San Frediano, 8, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Historic Centre of Florence and Uffizi ...
8.8/10 Excellent! (169 reviews)
"Loved our stay! Great area"

Reviewed on Feb 21, 2025

La Torre Del Cestello
Hostel Santa Monaca
Hostel Santa Monaca
Via Santa Monaca 6, Florence, FI
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and dry cleaning or laundry services. Popular attractions Uffizi Gallery and Historic Centre ...
8.2/10 Very Good! (51 reviews)
"The reviews told me the chances of getting bed bugs was likely. I did get bed bugs. And am now attempting to deal with this which continuing to travel. The actual place was okay but they need to fumigated. If you are ok with bedbugs it’s an okay place. Otherwise. Be warned. Also. The staff were not ..."

Reviewed on May 29, 2024

Hostel Santa Monaca
Ostello Tasso
Ostello Tasso
VIA VILLANI 15 , PIAZZA TASSO, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and rainfall showerheads. Popular attractions Uffizi Gallery and Historic Centre of Florence ...
9/10 Wonderful! (22 reviews)
3rd time staying here
"Ostello is a great location, away from the touristy areas. My husband and I chose this place, for the 3rd time because it’s in a local & quiet neighborhood. There are about 3 restaurants and a gelato place within 3 min of walking. We stayed for a week (for the 3rd time) and here’s things to consider. ..."

Reviewed on Dec 9, 2023

Ostello Tasso
1900 Artevita
1900 Artevita
Viale Raffaello Sanzio 2, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this B&B in Florence. Enjoy free WiFi, breakfast (surcharge), and housekeeping. Popular attractions Pitti Palace and Historic Centre of Florence are ...
8.6/10 Excellent! (161 reviews)
"Very calm"

Reviewed on Dec 26, 2024

1900 Artevita
Ottantotto Firenze
Ottantotto Firenze
Via dei Serragli 88, Florence, FI
Stay at this guesthouse in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (151 reviews)
"Loved it"

Reviewed on Mar 4, 2025

Ottantotto Firenze
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santo Spirito

Florence is a city that has a lot going on, but you have your sights set on Santo Spirito. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santo Spirito has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santo Spirito hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Florence so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santo Spirito underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santo Spirito city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santo Spirito cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santo Spirito at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $81
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santo Spirito hotel you want, book it, and never look back. Because your great escape is ahead of you.