Hotels Near
Santo Spirito

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking, and you save up to 60%!


Featured Santo Spirito Hotels

UNAHOTELS Vittoria Firenze
UNAHOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (986 reviews)
"Liked the service of the staff. Breakfast and dining options were really good. Stay was very pleasant and comfortable."

Reviewed on Apr 23, 2024

UNAHOTELS Vittoria Firenze
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (360 reviews)
"Loved the breakfast. Giovani was extremely helpful during our visit. Thank you!"

Reviewed on May 9, 2024

Hotel Horto Convento
1900 Artevita
1900 Artevita
Viale Raffaello Sanzio 2, Florence, FI
Stay at this B&B in Florence. Enjoy free WiFi, breakfast (surcharge), and housekeeping. Popular attractions Historic Center - Downtown and Uffizi Gallery are ...
8.8/10 Excellent! (128 reviews)
"Love the location of this Apartment very quiet and walkable to the centro.Feel very local. My view from my window is a park and a ferris wheel from a far that they light it up in the pm nice. Grocery is just around the corner."

Reviewed on Mar 29, 2024

1900 Artevita
Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the clean rooms in our reviews. ...
9.2/10 Wonderful! (889 reviews)
"This is a fantastic apartment.Very central and convenient. They run a tight ship. Stayed here before and will stay here again."

Reviewed on May 8, 2024

Palazzo Mannaioni Suites
Palazzo Oliveto
Palazzo Oliveto
Via Monte Oliveto, 32, Florence, Città Metropolitana di Firenze
Fully refundableReserve now, pay when you stay
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and a garden. Popular attractions Historic Center - Downtown and Uffizi Gallery are located ...
7.4/10 Good! (17 reviews)
"Too far from the center, one mile still Lot of walking"

Reviewed on Apr 26, 2024

Palazzo Oliveto
Casa Santo Nome di Gesù
Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Popular attractions Historic Center - Downtown and Uffizi Gallery ...
8.4/10 Very Good! (206 reviews)
"BIG ROOM, GARDEN AND QUIET AREA. A BRILL FIND."

Reviewed on Apr 11, 2024

Casa Santo Nome di Gesù
Drom Florence Rooms & Apartments
Drom Florence Rooms & Apartments
Via dei Serragli 137, Florence, Florence
Stay at this guesthouse in Florence. Enjoy free WiFi, a garden, and premium bedding. Our guests praise the clean rooms and the property condition in our reviews. ...
9.6/10 Exceptional! (72 reviews)
"Comfortable with a good sized usable bathroom with hot water in shower. Comfortable bed. They were very reluctant to let us check out at 1045 instead of 1000."

Reviewed on May 5, 2024

Drom Florence Rooms & Apartments
La Torre Del Cestello
La Torre Del Cestello
Via Borgo San Frediano, 8, Florence
Fully refundableReserve now, pay when you stay
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Historic Center - Downtown and Uffizi ...
8.8/10 Excellent! (138 reviews)
"The hotel isn’t difficult to find as long as you have a map, and it’s within a reasonable walking distance from the train station. There’s a small sign outside indicating the front door. I don’t recall any communication prior about the system for entering, but it seemed that I wasn’t the only one ..."

Reviewed on Mar 9, 2024

La Torre Del Cestello
Foresteria Valdese di Firenze - Casa per Ferie
Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49, Florence
Fully refundableReserve now, pay when you stay
Stay at this inn in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (57 reviews)
Very nice
"Great reception experience! Nice location. The tower bell is far enough to not bother much in the morning."

Reviewed on May 12, 2024

Foresteria Valdese di Firenze - Casa per Ferie
AdAstra Suites
AdAstra Suites
Via Del Campuccio, 53, Florence
Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (169 reviews)
"Quiet neighbourhood outside the crowds and touristy area, very Quiet surroundings, beautiful garden, good breakfast and coffee available all day, great helpful friendly staff,"

Reviewed on Mar 31, 2024

AdAstra Suites
Hotel Palazzo Guadagni
Hotel Palazzo Guadagni
3 out of 5
Piazza Santo Spirito 9, Florence, FI
Stay at this 3-star business-friendly hotel in Florence. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Popular attractions Uffizi Gallery and ...
9/10 Wonderful! (166 reviews)
"Amazing large room with beautiful tall windows and view. Will stay here again!"

Reviewed on Sep 7, 2023

Hotel Palazzo Guadagni
Hostel Santa Monaca
Hostel Santa Monaca
Via Santa Monaca 6, Florence, FI
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and dry cleaning or laundry services. Popular attractions Historic Center - Downtown and ...
7.8/10 Good! (39 reviews)
"Great location, clean and quiet."

Reviewed on Oct 24, 2023

Hostel Santa Monaca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santo Spirito

Florence is a city that has a lot going on, but you have your sights set on Santo Spirito. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santo Spirito has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santo Spirito hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Florence so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santo Spirito underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santo Spirito city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santo Spirito cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santo Spirito at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $128
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santo Spirito hotel you want, book it, and never look back. Because your great escape is ahead of you.