Hotels Near
Santo Spirito

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Featured Santo Spirito Hotels

Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (947 reviews)
"The Apt was great and clean. It has a kitchen with pots, silverware, plates glasses, microwave oven, stove, coffee machine etc. Great view from the terrace. Very comfortable beds. Good Wi-Fi. Walkable to all museums and restaurants. The check in was as scheduled and friendly. A great place to come ..."

Reviewed on Feb 19, 2025

Palazzo Mannaioni Suites
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (481 reviews)
"We meet here for three days with a group of friends. Two of us had cars so the hotel parking was convenient. Cost was €25 per night to park. The hotel was a wonderful calm oasis in the middle of a bustling city. The staff were excellent. They provided great restaurant recommendations, made great ..."

Reviewed on Feb 13, 2025

Hotel Horto Convento
UNAHOTELS Vittoria Firenze
UNAHOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (985 reviews)
"Was checked in by a lovely lady who made us aware of our VIP status and amenities with it. The hotel was kind enough to hold our luggage when we checked out so we could explore before heading to the train station. They were also kind enough to ask about arranging a taxi for pick up to take us to ..."

Reviewed on Dec 31, 2024

UNAHOTELS Vittoria Firenze
Casa Santo Nome di Gesù
Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (269 reviews)
"Everyone was friendly; place was very clean and breakfast was great!"

Reviewed on Jan 4, 2025

Casa Santo Nome di Gesù
Palazzo Oliveto
Palazzo Oliveto
Via Monte Oliveto, 32, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and a garden. Popular attractions Ponte Vecchio and Historic Centre of Florence are located ...
7.6/10 Good! (58 reviews)
"The property was very clean and quiet at night. I enjoyed how cleanly the place was and the staff were very nice especially with breakfast. Would stay again. Around a 30 min walk from the main attractions across the river."

Reviewed on Feb 17, 2025

Palazzo Oliveto
La Torre Del Cestello
La Torre Del Cestello
Via Borgo San Frediano, 8, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Historic Centre of Florence and Uffizi ...
9/10 Wonderful! (167 reviews)
"Loved our stay! Great area"

Reviewed on Feb 21, 2025

La Torre Del Cestello
Oltrarno Splendid
Oltrarno Splendid
Via dei Serragli 7, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.8/10 Exceptional! (77 reviews)
Top place to stay in Florence
"Attentive staff, helpful and great breakfast. Walk to everything."

Reviewed on Jan 14, 2025

Oltrarno Splendid
Ottantotto Firenze
Ottantotto Firenze
Via dei Serragli 88, Florence, FI
Stay at this guesthouse in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (150 reviews)
"We had such a wonderful stay here. A gorgeous boutique hotel in a great location, easy to walk to all the main attractions. The staff are absolutely lovely and very helpful. The complimentary breakfast was delicious and had a great variety. The best part is the style of the hotel, it is absolutely ..."

Reviewed on Jan 3, 2025

Ottantotto Firenze
Ostello Tasso
Ostello Tasso
VIA VILLANI 15 , PIAZZA TASSO, Florence, FI
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and rainfall showerheads. Popular attractions Ponte Vecchio and Basilica of Santa Maria ...
9/10 Wonderful! (22 reviews)
3rd time staying here
"Ostello is a great location, away from the touristy areas. My husband and I chose this place, for the 3rd time because it’s in a local & quiet neighborhood. There are about 3 restaurants and a gelato place within 3 min of walking. We stayed for a week (for the 3rd time) and here’s things to consider. ..."

Reviewed on Dec 9, 2023

Ostello Tasso
AdAstra Suites
AdAstra Suites
Via Del Campuccio, 53, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (194 reviews)
"Beautiful property! Excellent dining options."

Reviewed on Jan 18, 2025

AdAstra Suites
Foresteria Valdese di Firenze - Casa per Ferie
Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49, Florence, FI
Fully refundable
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.6/10 Excellent! (114 reviews)
"Our room was large, and the staff was friendly and helpful. It is a quick walk over the bridge to the heart of Florence, and there are many good dining options nearby."

Reviewed on Oct 31, 2024

Foresteria Valdese di Firenze - Casa per Ferie
Hotel Palazzo Guadagni
Hotel Palazzo Guadagni
3 out of 5
Piazza Santo Spirito 9, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Popular attractions Uffizi Gallery and ...
9/10 Wonderful! (185 reviews)
"The Hotel is so charming and exactly the vibe you want from Florence. The staff are amazing and they are very helpful guides to the city and have great, chic taste."

Reviewed on Dec 19, 2024

Hotel Palazzo Guadagni
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santo Spirito

Florence is a city that has a lot going on, but you have your sights set on Santo Spirito. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santo Spirito has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santo Spirito hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Florence so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santo Spirito underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santo Spirito city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santo Spirito cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santo Spirito at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $76
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santo Spirito hotel you want, book it, and never look back. Because your great escape is ahead of you.