Hotels Near
Santo Spirito

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Featured Santo Spirito Hotels

Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (981 reviews)
"We ordered the deck option and it was lovely and very good sized."

Reviewed on May 19, 2025

Palazzo Mannaioni Suites
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (517 reviews)
"All good"

Reviewed on May 28, 2025

Hotel Horto Convento
Foresteria Valdese di Firenze - Casa per Ferie
Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49, Florence, FI
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.8/10 Excellent! (136 reviews)
"The staff were absolutely amazing. Very kind and helpful. Checking in and out was a breeze and they also provided an electric kettle for us to use in our room. Only complaint was the walls were a little thin so we were able to hear when our neighbors were up and when they were in the hallway."

Reviewed on May 20, 2025

Foresteria Valdese di Firenze - Casa per Ferie
UNA HOTELS Vittoria Firenze
UNA HOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (989 reviews)
Location
"Excellent location 5 min walk to downtown"

Reviewed on May 25, 2025

UNA HOTELS Vittoria Firenze
La Torre Del Cestello
La Torre Del Cestello
Via Borgo San Frediano, 8, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Historic Centre of Florence and Uffizi ...
9/10 Wonderful! (179 reviews)
Fantastic Hotel
"It was so great! Very clean and much bigger room and shower than expected (with air conditioning). We felt very safe the entire time and were in an amazing location for walking places. Great bars/restaurants just feet from the entrance."

Reviewed on Apr 14, 2025

La Torre Del Cestello
Casa Santo Nome di Gesù
Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence, FI
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (283 reviews)
"Great people and great service. Comforting and nice."

Reviewed on May 23, 2025

Casa Santo Nome di Gesù
Hostel Santa Monaca
Hostel Santa Monaca
Via Santa Monaca 6, Florence, FI
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and dry cleaning or laundry services. Popular attractions Uffizi Gallery and Historic Centre ...
8.2/10 Very Good! (53 reviews)
"Неплохо для такой цены."

Reviewed on Oct 3, 2024

Hostel Santa Monaca
Appartamenti degli Artisti by Mmega
Appartamenti degli Artisti by Mmega
Via del Leone 3, Florence, FI
Stay at this apartment in Florence. Enjoy free WiFi, premium bedding, and air conditioning. Popular attractions Historic Centre of Florence and Uffizi Gallery ...
8.8/10 Excellent! (10 reviews)
Amazing spot
"Lovely apartment away from all the noise, yet close to everything within walking distance. Very spacious, super clean, and a place I would stay at again"

Reviewed on Apr 14, 2025

Appartamenti degli Artisti by Mmega
Palazzo Oliveto
Palazzo Oliveto
Via Monte Oliveto, 32, Florence, FI
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and a garden. Popular attractions Historic Centre of Florence and Uffizi Gallery are located ...
7.4/10 Good! (70 reviews)
"Great place for the value"

Reviewed on Apr 14, 2025

Palazzo Oliveto
Ostello Tasso
Ostello Tasso
VIA VILLANI 15 , PIAZZA TASSO, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and rainfall showerheads. Popular attractions Uffizi Gallery and Historic Centre of Florence ...
And off the path yet near everything
"This was an amazing place to stay, not too far from everything, and the staff was helpful. I will definitely be coming back."

Reviewed on Apr 3, 2025

Ostello Tasso
Hotel Firenze 2000
Hotel Firenze 2000
2 out of 5
Viale Raffaello Sanzio, 16, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Popular attractions Historic Centre of Florence and Uffizi Gallery ...
7/10 Good! (162 reviews)
"The staff was friendly and helped us with many things."

Reviewed on May 23, 2025

Hotel Firenze 2000
La Fonderia Firenze
La Fonderia Firenze
Via della Fonderia 65/A, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (151 reviews)
"Quiet and cozy. Friendly staff, safe location and a beautiful property."

Reviewed on May 6, 2025

La Fonderia Firenze
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santo Spirito

Florence is a city that has a lot going on, but you have your sights set on Santo Spirito. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santo Spirito has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santo Spirito hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Florence so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santo Spirito underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santo Spirito city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santo Spirito cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santo Spirito at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $104
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santo Spirito hotel you want, book it, and never look back. Because your great escape is ahead of you.