Hotels Near
Santo Spirito

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Featured Santo Spirito Hotels

UNA HOTELS Vittoria Firenze
UNA HOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (987 reviews)
"It was average really. Needs to be updated in the rooms blobby area and outside was very nice"

Reviewed on May 31, 2025

UNA HOTELS Vittoria Firenze
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (534 reviews)
"Staff were very helpful and professional. Speaking English was not a problem. The breakfast buffet had a lot fresh food, fruit and pastries to choose from"

Reviewed on Jul 7, 2025

Hotel Horto Convento
Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,000 reviews)
"Great location, rooms, and lovely staff. Enjoyed our stay."

Reviewed on Jul 3, 2025

Palazzo Mannaioni Suites
La Torre Del Cestello
La Torre Del Cestello
Via Borgo San Frediano, 8, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery ...
9/10 Wonderful! (189 reviews)
"The innkeepers are incredibly helpful, the room was lovely, and in a great location. They helped us celebrate our anniversary! We would stay again and again."

Reviewed on Jun 25, 2025

La Torre Del Cestello
Casa Santo Nome di Gesù
Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (296 reviews)
"The Air Conditioner was unable to cool the room down to the level we would have liked but did keep the room from being stifling hot. The historic nature of the building, location and morning breakfast were all big pluses for our family."

Reviewed on Jul 7, 2025

Casa Santo Nome di Gesù
Foresteria Valdese di Firenze - Casa per Ferie
Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.8/10 Excellent! (149 reviews)
"A traditional street near the river so perfect for Ufizzi and centre of Florence Lovely building with a lovely feel to it Friendly reception/ helpful ( parking not so easy and penalty fine on its way to is for coming to hotel in car)"

Reviewed on Jul 4, 2025

Foresteria Valdese di Firenze - Casa per Ferie
Hotel Firenze 2000
Hotel Firenze 2000
2 out of 5
Viale Raffaello Sanzio, 16, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Popular attractions Ponte Vecchio and Uffizi Gallery are located ...
7/10 Good! (164 reviews)
"The staff was friendly and helped us with many things."

Reviewed on May 23, 2025

Hotel Firenze 2000
B&B Mia Palace
B&B Mia Palace
Via della Fonderia 8, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this affittacamere in Florence. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Popular attractions Ponte Vecchio and Cathedral of Santa ...
8.2/10 Very Good! (105 reviews)
"It was all great, the service, breakfasts, and that lovely, helpful lady. I loved it, everything was perfect except for no elevator."

Reviewed on Jun 15, 2025

B&B Mia Palace
Ostello Tasso
Ostello Tasso
VIA VILLANI 15 , PIAZZA TASSO, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and rainfall showerheads. Popular attractions Ponte Vecchio and Uffizi Gallery are located ...
9/10 Wonderful! (29 reviews)
"Neat property. Air-conditioning did not work well though😱"

Reviewed on Jun 24, 2025

Ostello Tasso
Hotel Palazzo Guadagni
Hotel Palazzo Guadagni
3 out of 5
Piazza Santo Spirito 9, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Popular attractions Ponte Vecchio and ...
9/10 Wonderful! (196 reviews)
"This very hip hotel features a stylish rooftop bar—the hottest spot in the city—along with cool and friendly front desk staff, amazing rooms adorned with antique furniture and beautiful wall paintings, and stunning views throughout."

Reviewed on Jun 18, 2025

Hotel Palazzo Guadagni
1900 Artevita
1900 Artevita
Viale Raffaello Sanzio 2, Florence, FI
Stay at this B&B in Florence. Enjoy free WiFi, breakfast (surcharge), and housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery are located ...
8.6/10 Excellent! (166 reviews)
"Excellent accueil et emplacement. Merci, Shaila!"

Reviewed on Jun 6, 2025

1900 Artevita
Oltrarno Splendid
Oltrarno Splendid
Via dei Serragli 7, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.8/10 Exceptional! (86 reviews)
"We had a fantastic stay. The room we stayed in was spacious with all the amenities needed and had the necessary air con when temperatures were excessively high. The breakfast was excellent and set is up for the day. There were complimentary snacks, pastries, fruit, tea and coffee available throughout ..."

Reviewed on Jul 4, 2025

Oltrarno Splendid
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santo Spirito

Florence is a city that has a lot going on, but you have your sights set on Santo Spirito. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santo Spirito has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santo Spirito hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Florence so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santo Spirito underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santo Spirito city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santo Spirito cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santo Spirito at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $87
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santo Spirito hotel you want, book it, and never look back. Because your great escape is ahead of you.