Hotels Near
Santo Spirito

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Featured Santo Spirito Hotels

Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (976 reviews)
"Good experience all around."

Reviewed on May 6, 2025

Palazzo Mannaioni Suites
Foresteria Valdese di Firenze - Casa per Ferie
Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.8/10 Excellent! (130 reviews)
"Rooms were tidy and cosy, location is good with transport links to the station, main city centre is about a 15 minute walk"

Reviewed on May 5, 2025

Foresteria Valdese di Firenze - Casa per Ferie
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (507 reviews)
"beautiful, historic and quiet sophistication - enjoyed our stay!"

Reviewed on Apr 28, 2025

Hotel Horto Convento
UNA HOTELS Vittoria Firenze
UNA HOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
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Reviewed on Apr 13, 2025

UNA HOTELS Vittoria Firenze
La Torre Del Cestello
La Torre Del Cestello
Via Borgo San Frediano, 8, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Historic Centre of Florence and Uffizi ...
9/10 Wonderful! (176 reviews)
Fantastic Hotel
"It was so great! Very clean and much bigger room and shower than expected (with air conditioning). We felt very safe the entire time and were in an amazing location for walking places. Great bars/restaurants just feet from the entrance."

Reviewed on Apr 14, 2025

La Torre Del Cestello
Casa Santo Nome di Gesù
Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (279 reviews)
"Good"

Reviewed on Apr 25, 2025

Casa Santo Nome di Gesù
Hostel Santa Monaca
Hostel Santa Monaca
Via Santa Monaca 6, Florence, FI
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and dry cleaning or laundry services. Popular attractions Uffizi Gallery and Historic Centre ...
8.2/10 Very Good! (52 reviews)
"The reviews told me the chances of getting bed bugs was likely. I did get bed bugs. And am now attempting to deal with this which continuing to travel. The actual place was okay but they need to fumigated. If you are ok with bedbugs it’s an okay place. Otherwise. Be warned. Also. The staff were not ..."

Reviewed on May 29, 2024

Hostel Santa Monaca
Palazzo Oliveto
Palazzo Oliveto
Via Monte Oliveto, 32, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and a garden. Popular attractions Historic Centre of Florence and Uffizi Gallery are located ...
7.6/10 Good! (66 reviews)
"Great place for the value"

Reviewed on Apr 14, 2025

Palazzo Oliveto
Ostello Tasso
Ostello Tasso
VIA VILLANI 15 , PIAZZA TASSO, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and rainfall showerheads. Popular attractions Uffizi Gallery and Historic Centre of Florence ...
9/10 Wonderful! (25 reviews)
And off the path yet near everything
"This was an amazing place to stay, not too far from everything, and the staff was helpful. I will definitely be coming back."

Reviewed on Apr 3, 2025

Ostello Tasso
Hotel Firenze 2000
Hotel Firenze 2000
2 out of 5
Viale Raffaello Sanzio, 16, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Popular attractions Historic Centre of Florence and Uffizi Gallery ...
7/10 Good! (159 reviews)
"Staff pleasant. With few crosswalks unsafe and difficult to cross roads. Driving way too fast for residential area."

Reviewed on Oct 8, 2024

Hotel Firenze 2000
La Fonderia Firenze
La Fonderia Firenze
Via della Fonderia 65/A, Florence, FI
Fully refundableReserve now, pay when you stay
Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (149 reviews)
Huge room!
"This B&B was darling! Huge patio and room for a family! Great water pressure in the shower and the bed was comfortable. We didn’t eat breakfast as we had an early flight but we would definitely recommend this place!"

Reviewed on Apr 29, 2025

La Fonderia Firenze
Appartamenti degli Artisti by Mmega
Appartamenti degli Artisti by Mmega
Via del Leone 3, Florence, FI
Stay at this apartment in Florence. Enjoy free WiFi, premium bedding, and air conditioning. Popular attractions Historic Centre of Florence and Uffizi Gallery ...
9.2/10 Wonderful! (9 reviews)
Amazing spot
"Lovely apartment away from all the noise, yet close to everything within walking distance. Very spacious, super clean, and a place I would stay at again"

Reviewed on Apr 14, 2025

Appartamenti degli Artisti by Mmega
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santo Spirito

Florence is a city that has a lot going on, but you have your sights set on Santo Spirito. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santo Spirito has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santo Spirito hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Florence so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santo Spirito underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santo Spirito city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santo Spirito cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santo Spirito at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $124
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santo Spirito hotel you want, book it, and never look back. Because your great escape is ahead of you.