Search Deals on
Anton Vacation Packages

Build your package with 2 more options

Leaving from

Going to

Departing

Returning

Travelers

Room 1

Adults

ChildrenAges 2 to 17

InfantsYounger than 2

Add specific hotel dates

A winding road through lush green hills with a distant view of a valley and mountains under a partly cloudy sky.

Anton
Coclé
Panama
Mexico and Central America
Hotwire.com

Anton Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Museo Relic

2 out of 5

Price was $857, price is now $577 per person

$577

per person

Oct 19 - Oct 23

found 1 day ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

Stay at this hostel in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Totalmente diferente a como se ve en las fotos y mal trato por parte de la recepcionista

Reviewed on Sep 5, 2026

Megapolis Hotel Panamá

4.5 out of 5

Save 100% on your flight

Price was $1,517, price is now $761 per person

$761

per person

Oct 13 - Oct 17

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Central Hotel Panama Casco Viejo

4 out of 5

Save 100% on your flight

Price was $1,533, price is now $894 per person

$894

per person

Nov 12 - Nov 15

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

The Central Hotel Panama delivers an impeccable experience, combining the historic charm of Casco Antiguo with modern luxury and sophistication.

Reviewed on Sep 8, 2026

Riande Aeropuerto Hotel & Casino

4 out of 5

Price was $1,007, price is now $680 per person

$680

per person

Oct 13 - Oct 17

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.

Casa Mallet by Wynwood House

4 out of 5

Save 100% on your flight

Price was $2,956, price is now $2,000 per person

$2,000

per person

Oct 31 - Nov 7

found 1 day ago

Roundtrip flight included

New York (JFK) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Nice apartment ! Clean and great location

Reviewed on Aug 13, 2026

Las Americas Golden Tower Panama

4 out of 5

Price was $1,497, price is now $1,040 per person

$1,040

per person

Nov 22 - Nov 28

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Thanks

Reviewed on Sep 8, 2026

w Upscale 1BR w AC in Vibrant Obarrio

2 out of 5

Price was $1,070, price is now $745 per person

$745

per person

Oct 19 - Oct 23

found 1 day ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

Stay at this apartment in Panama City. Popular attractions Albrook Shopping Mall and Multiplaza Pacific Mall are located nearby.

Hotel San Felipe

4 out of 5

Price was $1,481, price is now $1,049 per person

$1,049

per person

Oct 24 - Nov 1

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and valet parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.