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Panama Vacation Packages

Panama Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
MARINN PLACE Financial District

MARINN PLACE Financial District

3.5 out of 5
Bella Vista
per person
May 18 - May 24
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
May 18 - May 24
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Save 100% on your flight
per person
May 26 - Jun 1
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 3.5-star beach lodge in Bocas del Toro. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions La Gruta Cave and Institute for Tropical Ecology & Conservation - Bocas del Toro Biological Station are located nearby.
The Gray by Wynwood House

The Gray by Wynwood House

2 out of 5
Bella Vista
Save 100% on your flight
per person
May 24 - May 30
found 11 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
La Coralina Island House

La Coralina Island House

3.5 out of 5
per person
May 26 - Jun 1
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 3.5-star beach hotel in Bocas del Toro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Paunch Beach and Tortuga Beach are located nearby.
Round the point Bungalow

Round the point Bungalow

3 out of 5
per person
May 26 - Jun 1
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 3-star cabin in Bastimentos. Enjoy free WiFi, dry cleaning or laundry services, and balconies or patios. Popular attractions Bastimento-Bocas del Toro Ferry Terminal and Up in the Hill Organic Coffee Farm are located nearby.
NAYARA Bocas del Toro

NAYARA Bocas del Toro

4 out of 5
Save 100% on your flight
per person
May 26 - Jun 1
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 4-star spa hotel in Isla Frangipani. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews.
La Loma Jungle Lodge

La Loma Jungle Lodge

2.5 out of 5
per person
May 26 - Jun 1
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Book a stay at this spa lodge in Bastimentos. Enjoy free breakfast, a full-service spa, and daily housekeeping. Popular attractions Nivida Bat Cave and Playa Larga are located nearby.

3-4 Night Vacations in Panama

Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
per person
May 21 - May 24
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
The Gray by Wynwood House

The Gray by Wynwood House

2 out of 5
Bella Vista
Save 100% on your flight
per person
Jun 5 - Jun 9
found 1 day ago
Roundtrip flight included
Port of Spain (POS) to Panama City (PTY)
Hotel La Compania, in the Unbound Collection by Hyatt

Hotel La Compania, in the Unbound Collection by Hyatt

4.5 out of 5
Casco Viejo
Save 100% on your flight
per person
May 21 - May 24
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
per person
May 21 - May 24
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

5-7 Night Vacations in Panama

Price found within the past 48 hours. Click for updated prices.
La Coralina Island House

La Coralina Island House

3.5 out of 5
per person
May 26 - Jun 1
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
May 18 - May 24
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Save 100% on your flight
per person
May 26 - Jun 1
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
The Gray by Wynwood House

The Gray by Wynwood House

2 out of 5
Bella Vista
Save 100% on your flight
per person
May 24 - May 30
found 11 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

Cheap Hotel Deals in Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
Dreams Playa Bonita Panama - All Inclusive
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Riande Urban Hotel

Riande Urban Hotel

3.5 out of 5
El Cangrejo; Calle Eusebio A, Morales, Panama City, Panama
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the bar and the helpful staff ...
Riande Urban Hotel
Grand Decameron Panama, A Trademark All Inclusive Resort

Grand Decameron Panama, A Trademark All Inclusive Resort

3.5 out of 5
Avenida Principal Farallon. Kilometro 11, Carretera Interamericana - Penonome, Rio Hato, Cocle
Stay at this 3.5-star beach property in Rio Hato. Enjoy free parking, 6 outdoor pools, and a full-service spa. Popular attractions Playa Blanca and Farallón ...
Grand Decameron Panama, A Trademark All Inclusive Resort
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
JW Marriott Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
Sheraton Grand Panama
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina, Panama City, Panama
Stay at this 3-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Principe Hotel and Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Fri, May 2 - Sat, May 3
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$232 Roundtrip, found 1 day ago
$232
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, May 2 from Juan Santamaría Intl. to Tocumen Intl., returning Sat, May 3, priced at $232 found 1 day ago
Delta
Wed, May 7 - Sat, May 10
MIA
Miami Intl.
PTY
Tocumen Intl.
$283 Roundtrip, found 2 days ago
$283
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, May 7 from Miami Intl. to Tocumen Intl., returning Sat, May 10, priced at $283 found 2 days ago
American Airlines
Sun, May 25 - Thu, Jun 5
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$295 Roundtrip, found 6 days ago
$295
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sun, May 25 from John F. Kennedy Intl. to Tocumen Intl., returning Thu, Jun 5, priced at $295 found 6 days ago
Delta
Wed, Jul 23 - Sat, Aug 16
LGA
LaGuardia
PTY
Tocumen Intl.
$415 Roundtrip, found 2 days ago
$415
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Jul 23 from LaGuardia to Tocumen Intl., returning Sat, Aug 16, priced at $415 found 2 days ago