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Choose from 1730 Panama City Hotel Deals
Hotel Riu Plaza Panama
"muy buena estadia, organizacion y limpieza"
Reviewed on Aug 27, 2026
Central Hotel Panama Casco Viejo
Waymore Hotel Spa & Casino
Megapolis Hotel Panamá
Principe Hotel and Suites
"This hotel was awesome all round 10 out of 10. Close or mins away from basically everything you would like, supermarket/restaurants/24 hours mini marts/bus station/Metro station etc. For the price this hotel was the best, quality service for your money. I just was would like a small refrigerator ..."
Reviewed on Aug 27, 2026
Waldorf Astoria Panama
"Desafortunadamente es mi peor experiencia con la marca Waldorf Astoria. Las instalaciones estan a medio reformarse. El trato en el check in muy indiferente, pero pero al check out. Nuestro vuelo se retraso y cancelaron nuestra habitacion porque no avisamos! (Veniamos volando con retrasos). Pero lo ..."
Reviewed on Aug 25, 2026
Aloft by Marriott Panama
Courtyard by Marriott Panama Multiplaza Mall
The Executive Hotel
Radisson Hotel Panama Canal
"Excelent staff"
Reviewed on Aug 27, 2026
Hyatt Regency Panama City
Renaissance Panama City Hotel
"I was very satisfied"
Reviewed on Aug 25, 2026
Find cheap hotels in Panama City
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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Panama City.
Choosing the right hotel in Panamá Province has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Panama City’s 1,730 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $85. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Panama City hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Panama City. No matter your reason for visiting Panama City, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Panama City hotels
Where can I find the best last-minute travel deals?
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How many hotels are there in Panama City?
With over 1,730 hotels in Panama City, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $85.
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