Find Cheap Deals on
Hotels in Panama


You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking, and you save up to 60%!

Top Cities in Panama

Hotels in Panama

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
Dreams Playa Bonita Panama - All Inclusive
Crowne Plaza Panama Airport, an IHG Hotel
Crowne Plaza Panama Airport, an IHG Hotel
4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
Crowne Plaza Panama Airport, an IHG Hotel
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
Plaza Paitilla Inn Hotel
Principe Hotel and Suites
Principe Hotel and Suites
3 out of 5
Via Argentina, Panama City, Panama
Stay at this 3-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Principe Hotel and Suites
Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
Decapolis Hotel Panama City
JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
JW Marriott Panama
Novotel Panama City
Novotel Panama City
4 out of 5
Calle Jose I. Fabrega y Thais de Pons, El Cangre, Bella Vista, Panama City, Panama
Stay at this 4-star family-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Novotel Panama City
Waldorf Astoria Panama
Waldorf Astoria Panama
5 out of 5
47th St. & Uruguay Street, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
Waldorf Astoria Panama
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 out of 5
Avenida Balboa, Panama City
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Megapolis Hotel Panamá
TRYP by Wyndham Panamá Centro
TRYP by Wyndham Panamá Centro
3.5 out of 5
Via Veneto, El Cangrejo Bellavista, Panama City, Panama
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the ...
TRYP by Wyndham Panamá Centro
W Panama
W Panama
5 out of 5
Calle Aquilino de la Guardia & Calle 50, Bella Vista, Panama City
Stay at this 5-star luxury hotel in Panama City. Enjoy 2 restaurants, 3 spa tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
W Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Panama 

2024 is the year you’ve decided to satisfy that travel urge. This trip you plan to mix it up a bit. You want a great place to stay, but also plan to hit up the places most tourists don’t even know about. So, can you get a great hotel in Panama for a steal? No doubt, and you’ll have cash left over to do this trip up the way you want.

This must be the place

Just how you like to live life a little differently, we do hotel bookings against the grain. You won’t have to decide between staying at one of the best hotels in Panama or scoring reservations at one of the hippest restaurants in Panama. With Hotwire, you can have both, and then some. After booking your place, you’ll have extra cash to tack on last-minute concert tickets, check out those off-beat sites, and do a little souvenir shopping because you’re all about setting your social feeds on fire, without burning your bank account.

Let us help you deal

You’re someone that likes to game the system, so choose the Hotwire Hot Rate. You’ll get the Panama hotel you’ve been eyeing at a price that’ll make you check twice to see if it’s real. Yes, the price is right. We have several ways for you to pick your preferred pad, and no matter which way you go, you’ll snag a hotel that you’ll brag about. Filter by:

  • Hotwire Hot Rate: You get some of the best hotels in Panama at ridiculously cheap rates—you’ll find out the hotel name after you book. You might even score a 4-star hotel at a 2-star price.

  • Price: Have a tight budget this go around? No worries. We have hotels for all price ranges, with rooms starting at $79.

  • Amenities: Heated pool? Maybe a private balcony with a view? Find the hotel that your dreams are made of.

Make your best year yet, and snap up one of the 3,014 killer Panama hotel deals and be the person that travel bloggers come to for advice.