Find Cheap Deals on
Casinos in Panama

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking, and you save up to 60%!




Featured Panama Casinos

Veneto Hotel & Casino
Veneto Hotel & Casino
5 out of 5
Eusebio A Morales Ave And Via Veneto Str, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Albrook Shopping Mall and Via ...
Veneto Hotel & Casino
JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is $166 per night from Dec 14 to Dec 15
$166
includes taxes & fees
Dec 14 - Dec 15
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
JW Marriott Panama
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 out of 5
56 y 57 East Street, Obarrio, Bella Vista, Panama City, Panama
The price is $164 per night from Nov 24 to Nov 25
$164
includes taxes & fees
Nov 24 - Nov 25
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and a casino. Our guests praise the helpful staff and the clean rooms ...
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
The price is $116 per night from Nov 17 to Nov 18
$116
includes taxes & fees
Nov 17 - Nov 18
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
Decapolis Hotel Panama City
Renaissance Panama City Hotel
Renaissance Panama City Hotel
4.5 out of 5
Via España & Ricardo Arias Street, Panama City, Panama
The price is $130 per night from Nov 22 to Nov 23
$130
includes taxes & fees
Nov 22 - Nov 23
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a casino, and breakfast (surcharge). Popular attractions Albrook Shopping Mall and Via Espana ...
Renaissance Panama City Hotel
Hilton Panama
Hilton Panama
5 out of 5
Balboa Ave. and Aquilino De La Guardia, Panama City
The price is $153 per night from Dec 6 to Dec 7
$153
includes taxes & fees
Dec 6 - Dec 7
Stay at this 5-star luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
Hilton Panama
Hotel y Casino Central Park Panama
Hotel y Casino Central Park Panama
3 out of 5
Calle Miguel Brostella, Panama City, Panama
Stay at this 3-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a casino. Popular attractions Albrook Shopping Mall and El Dorado ...
Hotel y Casino Central Park Panama
Riande Aeropuerto Hotel & Casino
Riande Aeropuerto Hotel & Casino
4 out of 5
Vía Tocumen, Entrance to Corredor Sur, Tocumen, Panama
The price is $134 per night from Nov 15 to Nov 16
$134
includes taxes & fees
Nov 15 - Nov 16
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
Riande Aeropuerto Hotel & Casino
 Grand Decameron Panama, A Trademark All Inclusive Resort
Grand Decameron Panama, A Trademark All Inclusive Resort
3.5 out of 5
KM 115 Carretera, Farallon, Rio Hato, Cocle
The price is $200 per night from Nov 19 to Nov 20
$200
includes taxes & fees
Nov 19 - Nov 20
Stay at this 3.5-star beach property in Rio Hato. Enjoy free breakfast, free parking, and 6 outdoor pools. Popular attractions Playa Blanca and Farallón Beach ...
Grand Decameron Panama, A Trademark All Inclusive Resort
The Saba Hotel
The Saba Hotel
3.5 out of 5
Panama Internacional zone,Argentina Ave, facing Parque Andres Bello, Panama City, Panama
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Albrook Shopping ...
The Saba Hotel
Radisson Colon 2,000 Hotel & Casino
Radisson Colon 2,000 Hotel & Casino
4 out of 5
Paseo Gorgas, Calle 13, Colon, Colon
The price is $108 per night from Nov 28 to Nov 29
$108
includes taxes & fees
Nov 28 - Nov 29
Stay at this 4-star spa hotel in Colon. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions ...
Radisson Colon 2,000 Hotel & Casino
Victoria Hotel and Suites Panama
Victoria Hotel and Suites Panama
3.5 out of 5
El Cangrejo, Calle D, Bella Vista, Panama City, Panama
The price is $87 per night from Nov 17 to Nov 18
$87
includes taxes & fees
Nov 17 - Nov 18
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff in our ...
Victoria Hotel and Suites Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Panama Casino Hotels

Are you feeling lucky? Well, you should because we have killer Panama casino hotels deals. Imagine relaxing in a cushy plush pad, and then sauntering downstairs to win it big at the tables with the cash you saved on your stay. You can live large, without busting your vacay budget. 

Winner, winner chicken dinner

So, why stay in a casino hotel in Panama? Well for starters, you’ll have a ton of entertainment options just steps from your room. Whether your good fortune is in the cards or in the roll of the dice, you can test your luck at almost any time of the day or night. Many of the casinos are ready whenever you are.  

Sure, there are the parlor games, but many casino hotels offer more than just games of chance. Your hotel may have a pretty fantastic pool (maybe two or three). Plus, all those games can work up an appetite, so many have restaurants galore right there in the hotel. Some even host concerts, too! You probably won’t feel the need to leave (which is kind of the point). But with all that extra cash you saved by booking with us, you can explore all that Panama offers.

The House doesn’t always win

When you’re at a casino hotel in Panama you’ve got one thing on your mind: winning. Luckily we can stack the odds in your favor. The Hotwire Hot Rate is your ace up the sleeve. Find the kind of hotel that spins your roulette wheel, and you may get it for a steal. Filter hotels by:

  • Price: Want more money for the tables? With rooms starting at $87, you have more cash to spare on the fun stuff.

  • Amenities: Looking to be a high roller? Then opt for a hotel flush with amenities like 24-hour room service, mini bar, and a California king.

  • Hotwire Hot Rate: We’ll tell you the name of the hotel after you book. You’re not really betting blind, if you know you’ll win the hand.

When you’re ready to play, or just relax and take it all in, book your Panama casino hotel through Hotwire. You’ll get the room you want and have cash left over to bet big or splurge on vacation activities outside the hotel grounds.