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Luxury Hotels in Panama

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Featured Panama Luxury Hotels

JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is $230 per night from Jan 10 to Jan 11
$230
includes taxes & fees
Jan 10 - Jan 11, 2025
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
JW Marriott Panama
Bristol Panama, a Registry Collection Hotel
Bristol Panama, a Registry Collection Hotel
5 out of 5
Avenida Aquilino de La Guardia, Bella Vista, Panama City, Panama
The price is $183 per night from Jan 3 to Jan 4
$183
includes taxes & fees
Jan 3 - Jan 4, 2025
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property ...
Bristol Panama, a Registry Collection Hotel
Waldorf Astoria Panama
Waldorf Astoria Panama
5 out of 5
47th St. & Uruguay Street, Panama City, Panama
The price is $186 per night from Jan 3 to Jan 4
$186
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
Waldorf Astoria Panama
American Trade Hotel
American Trade Hotel
4.5 out of 5
Plaza Herrera Casco Viejo, Panama City, Panama
The price is $345 per night from Dec 27 to Dec 28
$345
includes taxes & fees
Dec 27 - Dec 28
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
American Trade Hotel
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 out of 5
56 y 57 East Street, Obarrio, Bella Vista, Panama City, Panama
The price is $186 per night from Dec 29 to Dec 30
$186
includes taxes & fees
Dec 29 - Dec 30
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and a casino. Our guests praise the helpful staff and the clean rooms ...
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Hilton Panama
Hilton Panama
5 out of 5
Balboa Ave. and Aquilino De La Guardia, Panama City
The price is $186 per night from Jan 10 to Jan 11
$186
includes taxes & fees
Jan 10 - Jan 11, 2025
Stay at this 5-star luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
Hilton Panama
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
5 out of 5
340 Calle 3ra Buenaventura, Buenaventura Beach Community, El Chiru, Cocle
The price is $252 per night from Jan 23 to Jan 24
$252
includes taxes & fees
Jan 23 - Jan 24, 2025
Stay at this 5-star luxury resort in El Chiru. Enjoy free WiFi, free parking, and 12 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
Las Americas Golden Tower Panama
Las Americas Golden Tower Panama
4 out of 5
Av. Balboa con Calle 53, Paitilla, Panama City, Panama
The price is $188 per night from Jan 13 to Jan 14
$188
includes taxes & fees
Jan 13 - Jan 14, 2025
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Las Americas Golden Tower Panama
Marriott Panama Hotel
Marriott Panama Hotel
4 out of 5
Roosevelt Ave., Allbrook Mall, Panama City, Panama
The price is $157 per night from Jan 4 to Jan 5
$157
includes taxes & fees
Jan 4 - Jan 5, 2025
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Marriott Panama Hotel
Doubletree By Hilton Panama City El Carmen
Doubletree By Hilton Panama City El Carmen
4.5 out of 5
Via Espana Ave. Federico Boyd Bel, Panama City, Panama Province
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Popular attractions Albrook Shopping Mall and Avenida ...
Doubletree By Hilton Panama City El Carmen
Metro Hotel Panama
Metro Hotel Panama
3.5 out of 5
Via Veneto, Calle D El Cangrejo, Panama City, Panama
The price is $59 per night from Dec 26 to Dec 27
$59
includes taxes & fees
Dec 26 - Dec 27
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Albrook Shopping ...
Metro Hotel Panama
Summit Rainforest & Golf Resort
Summit Rainforest & Golf Resort
4 out of 5
Omar Torrijos Ave, Paraiso, Panama Canal, Panama City, Panama
The price is $110 per night from Jan 12 to Jan 13
$110
includes taxes & fees
Jan 12 - Jan 13, 2025
Stay at this 4-star golf hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
Summit Rainforest & Golf Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Panama

Imagine yourself living your best life in one of the luxury hotels in Panama. From the moment you step foot inside the Instagram-worthy property, you’re waited on hand-and-foot and treated like royalty amidst state-of-the-art amenities. You already know that the right hotel can be reason enough to book an entire trip. And the best luxury hotels in Panama are raising the bar for what it takes to be a truly exceptional place to stay. The luxury hotels Panama has in store for you are going the extra mile to create that perfect experience for when only the best will do. So what are you waiting for!?

Live the High Life for a Low Price

We’re going to let you in on one of the best-kept secrets about staying in luxury hotels. High-end doesn’t always mean high prices. Thanks to Hotwire Hot Rate hotel deals, even some of the top luxury hotels Panama is known for are available at incredible rates—where oversized suites also get oversized discounts. Booking an upscale vacation at cheap luxury hotels will make you feel like you’re riding high for a low, low price.

Living Large on the Small Scale

As the rules of exclusivity dictate—the smaller, the better. Arrive at the boutique scene of small luxury hotels in Panama, where irresistible indulgences come with a distinctly local touch. These luxe sanctuaries personalize every detail of your stay with features like individually -decorated suites and themes ranging from hip and trendy to old-fashioned romantic. When you book your trip on Hotwire, you’ll be saving big on these small boutique experiences, perfect for the style-seeking traveler who wants a high-class experience on a small-scale budget.

Frequently Asked Questions About Luxury Hotels

How to get last-minute deals on luxury hotels in Panama?

You shouldn’t have to compromise on price or style just because you’re tight for time. With Hotwire’s last-minute deals, you can get luxury hotels in Panama for less. In fact, you could enjoy significant savings compared to booking a listed rate two weeks earlier. 4-star hotels at 2-star prices? Yes, please! Now when you say you can’t wait for your next vacation, you’ll really mean it. Don’t wait to book a luxury trip—we’ll get you there right on time for a whole lot less. We’re talking rooms as low as $59 kind of less.

How many luxury hotels are in Panama?

Pick your preferred version of paradise from 3,055 luxury hotels in Panama. And you can bet the bottom-line of your glammed-up getaway will be less than you think when you score Hotwire Hot Rate deals on luxury accommodation in Panama.

How to book cheap luxury hotels in Panama?

Certainly, travel is about more than seeing the sights. It’s a chance to feel pampered, get away from everyday life, and step into the extraordinary. And what’s more extraordinary than finding cheap luxury hotels in Panama? It’s just one more reason why you’ll be bragging about your next vacation to your friends. Make Hotwire Hot Rate hotel deals your go-to travel hack for booking bougie trips and scoring envy-inducing rates. Now roll out the red carpet, Panama … a very savvy traveler is coming to town!