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Panama from $266

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Cheap round-trip flights to Panama

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Flights to Panama starting at $266

Have you been telling yourself, “2025 is the year I travel more and sit less”? Well, here we are and there you are. So, where are you going? Looks like a flight to Panama is calling. Good thing we can help you bag that flight out of town for cheap, so you can get your resolutions resolved.

Travel like you mean it

When you land it’s not straight to the tourist traps for you. You have things to do and see in Panama that aren’t on a map or in the “Best of. . .” guides. You know this region is filled with hidden haunts, locals-only know favorites, and the off-beat-so-weird-it’s-amazing places. And you plan to find every last one of them. Good thing you’ll save a grip of cash on your flight so you can daytrip far and wide.

You won’t have to wing it

So how do you score that killer deal on a flight to Panama? Easy, go through us. These aren’t pie in the sky deals, but ones you can actually score. Filter flights to Panama by:

  • Hotwire Hot Rate: Do you have a flexible schedule? Hit up the Hotwire Hot Rate and land a super cheap flight to Panama. We’ll reveal the airline and exact time after you book.
  • Price: How low can we go? Find out. We have prices from $266 to $475.
  • Duration: Want to get to Panama as fast as you can? Or maybe you don’t mind taking your time to save a few bucks here and there.
  • Departure or Arrival: Like to arrive in the a.m. to get your day going? Or are you a night owl that knows the best fun happens late night? The choice is yours.

So are you going to live up to those travel plans or kick the can to next year? Book your flight to Panama today and get going.

Last Minute Hotel Deals in Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (3,964 reviews)
RIU PLAZA Panama
"I really enjoyed my time there, breakfast was amazing"

Reviewed on May 30, 2025

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.4/10 Good! (1,008 reviews)
"Overall I had a great time and a great experience at this resort. The pros are that we stayed in a deluxe preferred room which gave us access to the preferred pool which was adults only. The service from Eric the bartender was fantastic! And the service from the gentleman at the poolside snack bar ..."

Reviewed on May 30, 2025

Dreams Playa Bonita Panama - All Inclusive
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
8.4/10 Very Good! (2,115 reviews)
"Good beds Restaurant in hotel"

Reviewed on May 31, 2025

Crowne Plaza Panama Airport by IHG
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Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111, Panama City, Panama
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.6/10 Good! (999 reviews)
"Good service..!"

Reviewed on May 29, 2025

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.