Search Cheap Flights to
Isla Grande

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Isla Grande Flights as Low as $392

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Jan 29 - Tue, Feb 4
CHS
Charleston Intl.
PTY
Tocumen Intl.
$392 Roundtrip, found 3 days ago
$392
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Jan 29 from Charleston Intl. to Tocumen Intl., returning Tue, Feb 4, priced at $392 found 3 days ago
American Airlines
Wed, Jan 29 - Tue, Feb 4
CHS
Charleston Intl.
PTY
Tocumen Intl.
$400 Roundtrip, found 3 days ago
$400
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Jan 29 from Charleston Intl. to Tocumen Intl., returning Tue, Feb 4, priced at $400 found 3 days ago
United
Thu, Jan 30 - Sun, Feb 2
CHS
Charleston Intl.
PTY
Tocumen Intl.
$412 Roundtrip, found 5 days ago
$412
Roundtrip
found 5 days ago
Select United flight, departing Thu, Jan 30 from Charleston Intl. to Tocumen Intl., returning Sun, Feb 2, priced at $412 found 5 days ago
American Airlines
Sat, Feb 1 - Tue, Feb 4
CHS
Charleston Intl.
PTY
Tocumen Intl.
$417 Roundtrip, found 5 days ago
$417
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Feb 1 from Charleston Intl. to Tocumen Intl., returning Tue, Feb 4, priced at $417 found 5 days ago
Delta
Sat, Feb 1 - Tue, Feb 4
CHS
Charleston Intl.
PTY
Tocumen Intl.
$418 Roundtrip, found 5 days ago
$418
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Feb 1 from Charleston Intl. to Tocumen Intl., returning Tue, Feb 4, priced at $418 found 5 days ago
Delta
Tue, Jan 21 - Sun, Feb 2
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$419 Roundtrip, found 21 hours ago
$419
Roundtrip
found 21 hours ago
Select Delta flight, departing Tue, Jan 21 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Sun, Feb 2, priced at $419 found 21 hours ago
American Airlines
Thu, Feb 6 - Tue, Feb 11
MCO
Orlando Intl.
PTY
Tocumen Intl.
$422 Roundtrip, found 6 days ago
$422
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Feb 6 from Orlando Intl. to Tocumen Intl., returning Tue, Feb 11, priced at $422 found 6 days ago
Copa
Mon, Feb 10 - Mon, Feb 17
KIN
Norman Manley Intl.
PTY
Tocumen Intl.
$444 Roundtrip, found 5 hours ago
$444
Roundtrip
found 5 hours ago
Select Copa flight, departing Mon, Feb 10 from Norman Manley Intl. to Tocumen Intl., returning Mon, Feb 17, priced at $444 found 5 hours ago
Copa
Mon, Feb 3 - Tue, Feb 18
TPA
Tampa Intl.
PTY
Tocumen Intl.
$455 Roundtrip, found 5 days ago
$455
Roundtrip
found 5 days ago
Select Copa flight, departing Mon, Feb 3 from Tampa Intl. to Tocumen Intl., returning Tue, Feb 18, priced at $455 found 5 days ago
Copa
Thu, Jan 16 - Wed, Jan 29
AUS
Austin-Bergstrom Intl.
PTY
Tocumen Intl.
$535 Roundtrip, found 6 days ago
$535
Roundtrip
found 6 days ago
Select Copa flight, departing Thu, Jan 16 from Austin-Bergstrom Intl. to Tocumen Intl., returning Wed, Jan 29, priced at $535 found 6 days ago
avianca
Fri, Jan 24 - Sun, Jan 26
MCO
Orlando Intl.
PTY
Tocumen Intl.
$573 Roundtrip, found 15 hours ago
$573
Roundtrip
found 15 hours ago
Select avianca flight, departing Fri, Jan 24 from Orlando Intl. to Tocumen Intl., returning Sun, Jan 26, priced at $573 found 15 hours ago
avianca
Fri, Dec 27 - Mon, Jan 6
MGA
Augusto C. Sandino Intl.
PTY
Tocumen Intl.
$585 Roundtrip, found 7 hours ago
$585
Roundtrip
found 7 hours ago
Select avianca flight, departing Fri, Dec 27 from Augusto C. Sandino Intl. to Tocumen Intl., returning Mon, Jan 6, priced at $585 found 7 hours ago
United
Mon, Feb 17 - Sun, Feb 23
DCA
Ronald Reagan Washington National
PTY
Tocumen Intl.
$649 Roundtrip, found 1 day ago
$649
Roundtrip
found 1 day ago
Select United flight, departing Mon, Feb 17 from Ronald Reagan Washington National to Tocumen Intl., returning Sun, Feb 23, priced at $649 found 1 day ago
Cayman Airways
Mon, Feb 10 - Thu, Feb 20
KIN
Norman Manley Intl.
PTY
Tocumen Intl.
$660 Roundtrip, found 5 hours ago
$660
Roundtrip
found 5 hours ago
Select Cayman Airways flight, departing Mon, Feb 10 from Norman Manley Intl. to Tocumen Intl., returning Thu, Feb 20, priced at $660 found 5 hours ago
Delta
Sat, Dec 28 - Sun, Dec 29
DFW
Dallas-Fort Worth Intl.
PTY
Tocumen Intl.
$688 Roundtrip, found 3 days ago
$688
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Dec 28 from Dallas-Fort Worth Intl. to Tocumen Intl., returning Sun, Dec 29, priced at $688 found 3 days ago
Delta
Sat, Dec 28 - Sun, Dec 29
DAL
Love Field
PTY
Tocumen Intl.
$728 Roundtrip, found 1 day ago
$728
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Dec 28 from Love Field to Tocumen Intl., returning Sun, Dec 29, priced at $728 found 1 day ago

Cheap Flights to Isla Grande

Fall in love at first flight with your vacation to Isla Grande by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Isla Grande on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Isla Grande, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Isla Grande

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Isla Grande with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PAC airport.

What is the cheapest month to fly to Isla Grande?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Isla Grande are in January, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Isla Grande?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Isla Grande.

What airport is best to fly into Isla Grande?

When you’re planning your trip to Isla Grande, convenience is the name of the game. Luckily, Isla Grande Tocumen Intl. Airport is nearby so you can deplane and get going on checking off everything on your Isla Grande must-do list.

How much are flights to Isla Grande?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Isla Grande on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $392, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Isla Grande?

The trick to saving a stack of cash on your flight to Isla Grande? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $392 right now, why wait?

Isla Grande Flight Information
Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Roundtrip price
$392

Last Minute Hotel Deals in Isla Grande

Coconut Grove Lodge
Coconut Grove Lodge
2.5 out of 5
North Coast, Isla Grande, Colon
Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, free parking, and a beach locale. Popular attractions Isla Mamey and Portobelo National ...
8.2/10 Very Good! (59 reviews)
"A very nice place for Panamanian standards. It’s obvious they are in the process of fixing things up but some things still need a little work. The room and beds were very comfortable. The complimentary breakfast and welcome beverage were outstanding. There is a small lagun to swim and snorkel in. ..."

Reviewed on Apr 10, 2022

Get rates
Coconut Grove Lodge
Sister Moon Hotel
Sister Moon Hotel
2 out of 5
Punta del Este, Isla Grande
Book a stay at this beach hotel in Isla Grande. Enjoy a beach locale, breakfast (surcharge), and daily housekeeping. Popular attractions Isla Mamey and Portobelo ...
6.6/10 (4 reviews)
Beautiful setting, basic rooms
"The hotel is in a beautiful setting overlooking the ocean. The pool and deck are great to relax in and watch the waves. The restaurant food was good (need hour notice for dinner). The rooms are really rustic and ours did not have AC. Also, note that there is not a public beach on Isla Grande. We ..."

Reviewed on Apr 15, 2017

Get rates
Sister Moon Hotel
Brother Sun Villas
Brother Sun Villas
3 out of 5
Camino Al Faro, Isla Grande
Stay at this 3-star beach vacation home in Isla Grande. Enjoy a beach locale, daily housekeeping, and a garden. Popular attractions Isla Mamey and Portobelo ...
3/10 (2 reviews)
Wrong advertisement
"This is where advertisement they told me that display have AC Wi-Fi TV and they don’t have to bring a lot of money for this room and he’s not worth it I wanted to cancel the second night and the lady didn’t want to return my money back I call hotels.com and complained about it and they didn’t do ..."

Reviewed on Oct 15, 2017

Get rates
Brother Sun Villas
Ordovician Beach Resort
Ordovician Beach Resort
4.5 out of 5
Isla Grande, Isla Grande, Colon
Stay at this 4.5-star luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National ...
Get rates
Ordovician Beach Resort
Casa Congo - Rayo Verde - Restaurante
Casa Congo - Rayo Verde - Restaurante
3 out of 5
Calle Genea, Portobelo
The price is $83 per night from Jan 3 to Jan 4
$83
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 3-star beach B&B in Portobelo. Enjoy free breakfast, an airport shuttle (surcharge), and daily housekeeping. Popular attractions San Felipe Church ...
8.8/10 Excellent! (81 reviews)
"Quaint B&B in the heart of Portobelo. Easy walking to restaurants, the museum, the church and other attractions."

Reviewed on Dec 16, 2024

Casa Congo - Rayo Verde - Restaurante
Dive Center Portobelo, SA
Dive Center Portobelo, SA
3 out of 5
Vía Portobelo, Portobelo, Provincia de Colón
The price is $100 per night from Jan 7 to Jan 8
$100
includes taxes & fees
Jan 7 - Jan 8, 2025
Stay at this 3-star hotel in Portobelo. Enjoy free WiFi, breakfast (surcharge), and a beach shuttle (surcharge). Popular attractions Mirador Perú and Real Aduana ...
8/10 Very Good! (3 reviews)
"Clean and well kept. Welcoming and they also were very Helpful towards your own personal destinations and activities"

Reviewed on Mar 29, 2023

Dive Center Portobelo, SA
BOHEMIAN - Hostel
BOHEMIAN - Hostel
1 out of 5
Puerto Lindo Primera Izquierda, Puerto Lindo, Colon
Stay at this hostel in Puerto Lindo. Enjoy a free beach shuttle and parking (surcharge). Popular attractions Isla Mamey and Portobelo National Park are located ...
Get rates
BOHEMIAN - Hostel
Ranchos de Chalia
Ranchos de Chalia
3 out of 5
Portobelo via Puerto Lindo, Unit 3, Puerto Lindo, Colón
The price is $176 per night from Dec 29 to Dec 30
$176
includes taxes & fees
Dec 29 - Dec 30
Stay at this 3-star hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are ...
Ranchos de Chalia
See all 60 properties in Isla Grande
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.