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Isla Grande Vacation Packages

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Isla Grande Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Renaissance Panama City Hotel

Renaissance Panama City Hotel

5 out of 5
Price was $1,138, price is now $735 per person
$735
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and breakfast (surcharge). Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
The property needs to be updated

Reviewed on Oct 21, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $2,264, price is now $970 per person
$970
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $3,081, price is now $1,413 per person
$1,413
per person
Dec 26 - Dec 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Property was clean and nice, breakfast was excellent.

Reviewed on Oct 20, 2026

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,330, price is now $817 per person
$817
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.

W Panama

W Panama

5 out of 5
Price was $1,570, price is now $987 per person
$987
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,301, price is now $882 per person
$882
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Perfect location and clean

Reviewed on Oct 22, 2026

Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3 out of 5
Price was $2,477, price is now $1,684 per person
$1,684
per person
Jan 11 - Jan 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, cable TV channels, and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Price was $1,313, price is now $918 per person
$918
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Isla Grande Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Bella Vista
Price was $1,240, price is now $867 per person
$867
per person
Dec 28 - Jan 1
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $3,081, price is now $1,413 per person
$1,413
per person
Dec 26 - Dec 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $2,419, price is now $1,161 per person
$1,161
per person
Dec 26 - Dec 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
W Panama

W Panama

5 out of 5
Bella Vista
Price was $1,551, price is now $1,062 per person
$1,062
per person
Dec 26 - Dec 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

Isla Grande Vacation Packages 5-7 Night Stays

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Tocumen Airport
Price was $1,330, price is now $817 per person
$817
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $2,264, price is now $970 per person
$970
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $3,605, price is now $1,788 per person
$1,788
per person
Dec 26 - Dec 31
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
W Panama

W Panama

5 out of 5
Bella Vista
Price was $1,570, price is now $987 per person
$987
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Fri, Nov 6 - Wed, Nov 11
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$264 Roundtrip, just found
$264
Roundtrip
just found
Select Copa flight, departing Fri, Nov 6 from Juan Santamaría Intl. to Tocumen Intl., returning Wed, Nov 11, priced at $264 just found
Copa
Thu, Jan 21 - Tue, Jan 26
MIA
Miami Intl.
PTY
Tocumen Intl.
$542 Roundtrip, just found
$542
Roundtrip
just found
Select Copa flight, departing Thu, Jan 21 from Miami Intl. to Tocumen Intl., returning Tue, Jan 26, priced at $542 just found
United
Thu, Jan 21 - Tue, Jan 26
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$557 Roundtrip, just found
$557
Roundtrip
just found
Select United flight, departing Thu, Jan 21 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Tue, Jan 26, priced at $557 just found
Delta
Mon, Mar 29 - Wed, Apr 14
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$590 Roundtrip, found 3 hours ago
$590
Roundtrip
found 3 hours ago
Select Delta flight, departing Mon, Mar 29 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Wed, Apr 14, priced at $590 found 3 hours ago