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Panama from $312

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Cheap round-trip flights to Panama

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Flights to Panama starting at $312

Have you been telling yourself, “2026 is the year I travel more and sit less”? Well, here we are and there you are. So, where are you going? Looks like a flight to Panama is calling. Good thing we can help you bag that flight out of town for cheap, so you can get your resolutions resolved.

Travel like you mean it

When you land it’s not straight to the tourist traps for you. You have things to do and see in Panama that aren’t on a map or in the “Best of. . .” guides. You know this region is filled with hidden haunts, locals-only know favorites, and the off-beat-so-weird-it’s-amazing places. And you plan to find every last one of them. Good thing you’ll save a grip of cash on your flight so you can daytrip far and wide.

You won’t have to wing it

So how do you score that killer deal on a flight to Panama? Easy, go through us. These aren’t pie in the sky deals, but ones you can actually score. Filter flights to Panama by:

  • Hotwire Hot Rate: Do you have a flexible schedule? Hit up the Hotwire Hot Rate and land a super cheap flight to Panama. We’ll reveal the airline and exact time after you book.
  • Price: How low can we go? Find out. We have prices from $312 to $1,021.
  • Duration: Want to get to Panama as fast as you can? Or maybe you don’t mind taking your time to save a few bucks here and there.
  • Departure or Arrival: Like to arrive in the a.m. to get your day going? Or are you a night owl that knows the best fun happens late night? The choice is yours.

So are you going to live up to those travel plans or kick the can to next year? Book your flight to Panama today and get going.

Last Minute Hotel Deals in Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (5,421 reviews)
Great stay at the hotel. Loved the pool and the location.

Reviewed on May 14, 2026

Opens in a new windowHotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (2,536 reviews)
This is very convenient, we have stayed there a few times. The buffet is not worth it, the last time it was mediocre at best for dinner and breakfast, not worth what they charge.

Reviewed on May 13, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
9.2/10 Wonderful! (1,124 reviews)
Good breakfast

Reviewed on May 13, 2026

Opens in a new windowThe Executive Hotel
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Gran Evenia Bijao & Convention Center

Gran Evenia Bijao & Convention Center

3.5 out of 5
Carretera Interamericana km 108 Rio Hato
Book a stay at this beach hotel in Rio Hato. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.2/10 Very Good! (1,008 reviews)
Cheap alcohol. Food was ok nothing special. Maintenance of the rooms was poor. Stayed for a night and couldn’t book a restaurant because it had to be done in the morning and the check in is at 3 pm. Cheap place

Reviewed on May 12, 2026

Opens in a new windowGran Evenia Bijao & Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.