Hotels Near
San Francisco

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Featured San Francisco Hotels

Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (1,665 reviews)
"We were so confused trying to find the location based on the map... it's a little bit hidden. We couldn't believe the view! the windows in this hotel rooms are amazing. They had very nice staff we had a nice drink in the bar but we couldn't figure out the dinner option there so we went to Market. ..."

Reviewed on Oct 29, 2024

Plaza Paitilla Inn Hotel
Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,013 reviews)
"Our stay at decapolis was awesome the staff was so welcoming 😘"

Reviewed on Nov 2, 2024

Decapolis Hotel Panama City
JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,011 reviews)
"Nice"

Reviewed on Nov 3, 2024

JW Marriott Panama
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 out of 5
Avenida Balboa, Panama City
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (673 reviews)
"The hotel was great but the area has seen better days. It was safe but nothing near by except the casino and dying mall."

Reviewed on Nov 1, 2024

Megapolis Hotel Panamá
Las Americas Golden Tower Panama
Las Americas Golden Tower Panama
4 out of 5
Av. Balboa con Calle 53, Paitilla, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,009 reviews)
"Exelente lugar, muy buena ubicación"

Reviewed on Nov 1, 2024

Las Americas Golden Tower Panama
Ramada Plaza By Wyndham Panama Punta Pacífica
Ramada Plaza By Wyndham Panama Punta Pacífica
4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,006 reviews)
"Clean, tasty food, close to restaurants, friendly staff."

Reviewed on Oct 28, 2024

Ramada Plaza By Wyndham Panama Punta Pacífica
Residence Inn by Marriott Panama City
Residence Inn by Marriott Panama City
4 out of 5
CALLE RAMON H JURADO EDIFICO P, Panama City
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (383 reviews)
"We loved everything about our stay at the Residence Inn by Marriott. From its convenient location in the Pacific Center shopping plaza, friendly staff, complimentary free breakfast, to the facilities such as the gym and laundry mat. Not to mention we felt comfortable and completely safe in the area! ..."

Reviewed on Nov 2, 2024

Residence Inn by Marriott Panama City
Sheraton Grand Panama
Sheraton Grand Panama
4.5 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (812 reviews)
"The front desk staff was extremely hepful with suggestions of local tours and experiences. They were also quite thoughtful- sent a birthday cake to my mom's room. They added joy to our overall experience"

Reviewed on Nov 1, 2024

Sheraton Grand Panama
Aloft Panama
Aloft Panama
3.5 out of 5
Via Israel & Calle 76, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (761 reviews)
"Beautiful. Great. 10/10. Had a cancelled flight and this was great and I’m a really great area. I’d stay here again for a couple of nights."

Reviewed on Oct 6, 2024

Aloft Panama
Courtyard by Marriott Panama Multiplaza Mall
Courtyard by Marriott Panama Multiplaza Mall
4 out of 5
Via Israel Multiplaza Pacific Mall, Panama City, Panama
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
8.8/10 Excellent! (1,000 reviews)
"Smell like carpet wet"

Reviewed on Sep 11, 2024

Courtyard by Marriott Panama Multiplaza Mall
Boutique Apartments Panamá Coco del Mar
Boutique Apartments Panamá Coco del Mar
3.5 out of 5
Av. Cincuentenario, Panama City, Provincia de Panamá
Stay at this 3.5-star apartment in Panama City. Enjoy free WiFi, an outdoor pool, and a fitness center. Popular attractions Albrook Shopping Mall and Multiplaza ...
7.4/10 Good! (52 reviews)
"I like the location in the city and the view. The apartment was modern and up to date. They also responded to our request whetever we reached out to them. The parking was secure and safe. There was restaurant and shopping near by. I would recommend and would return in the future."

Reviewed on Aug 30, 2024

Boutique Apartments Panamá Coco del Mar
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (3,229 reviews)
"Breakfast convenience , close proximity to train station"

Reviewed on Nov 2, 2024

Hotel Riu Plaza Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in San Francisco

Panama City is a city that has a lot going on, but you have your sights set on San Francisco. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that San Francisco has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of San Francisco hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Panama City so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the San Francisco underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the San Francisco city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of San Francisco cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in San Francisco at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $59
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the San Francisco hotel you want, book it, and never look back. Because your great escape is ahead of you.