Hotels Near
San Francisco

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Featured San Francisco Hotels

Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,121 reviews)
Just as described
"Fantastic stay. Clean and front desk person was great with providing details about places to visit."

Reviewed on Mar 25, 2025

Decapolis Hotel Panama City
JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,003 reviews)
"Love the staff"

Reviewed on Mar 24, 2025

JW Marriott Panama
Ramada Plaza By Wyndham Panama Punta Pacífica
Ramada Plaza By Wyndham Panama Punta Pacífica
4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,010 reviews)
"Great location and nearby dining"

Reviewed on Mar 30, 2025

Ramada Plaza By Wyndham Panama Punta Pacífica
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 out of 5
Avenida Balboa, Panama City
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (832 reviews)
"10/10"

Reviewed on Mar 18, 2025

Megapolis Hotel Panamá
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (1,984 reviews)
"This is my 2nd time staying at Paitilla Inn hotel. The rooms have been updated since 2019 and the bay view is always a must. It's close to everything including the walk along the malecon to enjoy some street food and culture plus it gives you full access to all of restaurants to view in the area ..."

Reviewed on Mar 29, 2025

Plaza Paitilla Inn Hotel
Las Americas Golden Tower Panama
Las Americas Golden Tower Panama
4 out of 5
Av. Balboa con Calle 53, Paitilla, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,007 reviews)
"Central location"

Reviewed on Mar 29, 2025

Las Americas Golden Tower Panama
Sheraton Grand Panama
Sheraton Grand Panama
4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (855 reviews)
"My stay was good, didn’t like packing lot location, but overall good"

Reviewed on Mar 29, 2025

Sheraton Grand Panama
Residence Inn by Marriott Panama City
Residence Inn by Marriott Panama City
4 out of 5
CALLE RAMON H JURADO EDIFICO P, Panama City
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (442 reviews)
Excellent resort
"The Residence inn in Panama is at a great location. Easy access to great restaurants, close to a 5 star mall, and great location for rental launch into the rest of Panama. The rooms are clean and roomy. Great kitchen with all you might need . The breakfast was excellent with a selection including ..."

Reviewed on Mar 25, 2025

Residence Inn by Marriott Panama City
Courtyard by Marriott Panama Multiplaza Mall
Courtyard by Marriott Panama Multiplaza Mall
4 out of 5
Via Israel Multiplaza Pacific Mall, Panama City, Panama
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
8.8/10 Excellent! (1,004 reviews)
"The staff service was excellent."

Reviewed on Mar 31, 2025

Courtyard by Marriott Panama Multiplaza Mall
Aloft Panama
Aloft Panama
3.5 out of 5
Via Israel & Calle 76, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (793 reviews)
"Great place to stay if your traveling with family."

Reviewed on Mar 27, 2025

Aloft Panama
Boutique Apartments Panamá Coco del Mar
Boutique Apartments Panamá Coco del Mar
3.5 out of 5
Av. Cincuentenario, Panama City, Provincia de Panamá
Stay at this 3.5-star apartment in Panama City. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Albrook Shopping Mall and Multiplaza ...
7.2/10 Good! (84 reviews)
"Apartment is in a great location. Staff were super friendly. Lots of restaurants nearby and easy access to Hwy 1. Pool is really nice. If I was local and driving into the city for vacation some of these would be irrelevant but traveling internationally you don’t really want to pack some of essentials ..."

Reviewed on Mar 29, 2025

Boutique Apartments Panamá Coco del Mar
San Francisco by Wynwood House
San Francisco by Wynwood House
4 out of 5
C. 73 Este, Panama City, Provincia de Panamá
Stay at this 4-star aparthotel in Panama City. Enjoy free WiFi, valet parking (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
9.4/10 Exceptional! (32 reviews)
"I likes the location, the building is really nice and has the amenities i desired. The unit was very tastefully decorated and top of the line appliances,and housewares. The floor i was on was noisy. Smoke detectors work, went off Tuesday 2:30 a.m. and Wednesday 3:30 a.m. Why someone cooking that ..."

Reviewed on Mar 27, 2025

San Francisco by Wynwood House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in San Francisco

Panama City is a city that has a lot going on, but you have your sights set on San Francisco. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that San Francisco has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of San Francisco hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Panama City so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the San Francisco underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the San Francisco city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of San Francisco cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in San Francisco at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $93
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the San Francisco hotel you want, book it, and never look back. Because your great escape is ahead of you.