Search for Cheap Deals on
Hotels in Santa Clara

Choose from 1456 Santa Clara Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
  • 30 min drive from Culebra Cut
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (4,114 reviews)
"The hotel was clean, buffet breakfast was good, bar service was good, pool was clean and staff was excellent. I thought we would get an armband to show that we are staying at the Hotel Riu Plaza. I didn't like the fact that anyone could just walk in on the property without being questioned by the ..."

Reviewed on Jul 21, 2025

Get rates
Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
  • 34 min drive from Culebra Cut
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.2/10 Good! (1,012 reviews)
"NA"

Reviewed on Jul 20, 2025

Get rates
Dreams Playa Bonita Panama - All Inclusive
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
  • 32 min drive from Culebra Cut
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (905 reviews)
"Food was good but not excellent ,bedrooms clean but in the tired side"

Reviewed on Jul 19, 2025

Get rates
Sheraton Grand Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
  • 28 min drive from Culebra Cut
Stay at this 4-star spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located ...
9/10 Wonderful! (347 reviews)
"I liked the hotel. It came with free breakfast. The room was clean and comfortable, also the mattress was very comfortable. The only things I didn't like were the shower drained VERY, VERY slowly and we had to repeatedly request washcloths and toilet paper. Otherwise, it was a good stay."

Reviewed on Jul 18, 2025

Get rates
Waymore Hotel Spa & Casino
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111, Panama City, Panama
  • 29 min drive from Culebra Cut
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.6/10 Good! (1,003 reviews)
"Staff was great! Front desk agent Christian very nice and friendly! Breakfast was nice and restaurant staff always very helpful."

Reviewed on Jul 20, 2025

Get rates
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5 out of 5
Km 6 Road to Veracruz, Veracruz, Panama
  • 34 min drive from Culebra Cut
Stay at this 5-star luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8/10 Very Good! (1,004 reviews)
"Love it i would go back"

Reviewed on Jul 21, 2025

Get rates
The Westin Playa Bonita Panama
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
  • 32 min drive from Culebra Cut
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,004 reviews)
JW Marriott Experience
"The hotel was spotless, and the staff were friendly. It's a bit expensive, as I was expecting more of a luxury hotel. The only bad thing was the breakfast one morning, when everything was cold and the cup of coffee wasn't hot. The toast was hard as a rock, so it was a total disappointment for the ..."

Reviewed on Jul 18, 2025

Get rates
JW Marriott Panama
Ramada Plaza By Wyndham Panama Punta Pacífica

Ramada Plaza By Wyndham Panama Punta Pacífica

4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
  • 31 min drive from Culebra Cut
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,005 reviews)
My group.
"The Ramada is a really nice place to stay. One of the young ladies recognize us because this was our third time staying at this hotel. Parking is a little tricky because of a hill if you're driving a van. The parking staff was very friendly too. The breakfast was good but could be a lot hotter. The ..."

Reviewed on Jul 22, 2025

Get rates
Ramada Plaza By Wyndham Panama Punta Pacífica
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina, Panama City, Panama
  • 29 min drive from Culebra Cut
Stay at this 3-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,409 reviews)
"Staff"

Reviewed on Jul 19, 2025

Get rates
Principe Hotel and Suites
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
  • 30 min drive from Culebra Cut
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (957 reviews)
"I would stay again. Was really nice"

Reviewed on Jul 18, 2025

Get rates
Megapolis Hotel Panamá
Studio Coliving

Studio Coliving

4.5 out of 5
Av. Ricardo Arango y, Av. Federico Boyd, Panama City, Panama
  • 29 min drive from Culebra Cut
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
8/10 Very Good! (410 reviews)
"None"

Reviewed on Jul 19, 2025

Get rates
Studio Coliving
Novotel Panama City

Novotel Panama City

4 out of 5
Calle Jose I. Fabrega y Thais de Pons, El Cangre, Bella Vista, Panama City, Panama
  • 28 min drive from Culebra Cut
Stay at this 4-star family-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,002 reviews)
Great stay, nice staff, delicious breakfast
"The staff was nice and the room was spacious and comfortable. There was a plate of fruit waiting for us which was really nice. The breakfast was delicious too! The taxi and tour group in the lobby was super helpful and took us to the airport and Casco Viejo."

Reviewed on Jul 18, 2025

Get rates
Novotel Panama City
See all 1,456 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Santa Clara

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Santa Clara hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Santa Clara.

Choosing the right hotel in Panamá Oeste Province has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Santa Clara’s 1,456 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $51. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Santa Clara hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Santa Clara. No matter your reason for visiting Santa Clara, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Santa Clara hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Santa Clara for as low as $51.

How many hotels are there in Santa Clara?

With over 1,456 hotels in Santa Clara, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $51.

How to find cheap car rentals in Santa Clara?

Finding a cheap car rental deal in Santa Clara is as easy as scoring cheap hotels in Santa Clara. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.