Search for Cheap Deals onHotels in Santa Clara
Check Last Minute Santa Clara Hotel Deals
Choose from 1456 Santa Clara Hotel Deals

Hotel Riu Plaza Panama
Reviewed on Jul 21, 2025

Dreams Playa Bonita Panama - All Inclusive
Reviewed on Jul 20, 2025

Sheraton Grand Panama
Reviewed on Jul 19, 2025

Waymore Hotel Spa & Casino
Reviewed on Jul 18, 2025

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Reviewed on Jul 20, 2025

The Westin Playa Bonita Panama
Reviewed on Jul 21, 2025

JW Marriott Panama
Reviewed on Jul 18, 2025

Ramada Plaza By Wyndham Panama Punta Pacífica
Reviewed on Jul 22, 2025

Principe Hotel and Suites
Reviewed on Jul 19, 2025

Megapolis Hotel Panamá
Reviewed on Jul 18, 2025

Studio Coliving
Reviewed on Jul 19, 2025

Novotel Panama City
Reviewed on Jul 18, 2025
Find cheap hotels in Santa Clara
You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Santa Clara hotel with Hotwire to complete your one-of-a-kind travel checklist.
For you, intrepid voyager, Hotwire has a large selection of the best hotels in Santa Clara.
Choosing the right hotel in Panamá Oeste Province has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Santa Clara’s 1,456 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $51. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Santa Clara hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Santa Clara. No matter your reason for visiting Santa Clara, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Santa Clara hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Santa Clara for as low as $51.
How many hotels are there in Santa Clara?
With over 1,456 hotels in Santa Clara, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $51.
How to find cheap car rentals in Santa Clara?
Finding a cheap car rental deal in Santa Clara is as easy as scoring cheap hotels in Santa Clara. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
Top Booked Hotels in Santa Clara
- Hotel Riu Plaza Panama
- Dreams Playa Bonita Panama - All Inclusive
- Sheraton Grand Panama
- Hotel El Panama by Faranda Grand, a member of Radisson Individuals
- The Westin Playa Bonita Panama
- JW Marriott Panama
- Ramada Plaza By Wyndham Panama Punta Pacífica
- Principe Hotel and Suites
- Novotel Panama City
- Decapolis Hotel Panama City
- Hospedium Princess Hotel Panama
- The Executive Hotel
- Waldorf Astoria Panama
- Hotels near Culebra Cut
- Hotels near Albrook Shopping Mall
- Hotels near Multiplaza Pacific Mall
- Hotels near Cinta Costera
- Hotels near Avenida Balboa
- Hotels near Amador Causeway
- Hotels near Via Espana
- Hotels near Colon Free Zone
- Hotels near El Dorado Mall
- Hotels near Fuerte Amador Resort & Marina
- Hotels near Miraflores Locks
- Hotels near Veracruz Beach
- Hotels near Gamboa Rainforest Resort
- Hotels near Panama Viejo
- Hotels near Metromall Panama
- Hotels near Calle 50
- Hotels near ATLAPA Conventions Center
- Hotels near Iglesia del Carmen
- Hotels near Uruguay Street
- Hotels near Los Pueblos Commercial Center
- Panama City Hotels
- Veracruz Hotels
- Colon Hotels
- Tocumen Hotels
- Ancon Hotels
- Taboga Hotels
- Playa Bonita Village Hotels
- San Miguelito Hotels
- 24 de Diciembre Hotels
- La Chorrera Hotels
- Panama Canal Zone Hotels
- Gamboa Hotels
- Arraijan Hotels
- Cerro Azul Hotels
- Las Cumbres Hotels
- Caimitillo Hotels
- Capira Hotels
- Vacamonte Hotels
- Caribbean West Hotels
- Las Mañanitas Hotels