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Santa Clara

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Santa Clara Flights as Low as $276

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Sat, Sep 6 - Wed, Sep 10
MIA
Miami Intl.
PTY
Tocumen Intl.
$276 Roundtrip, found 2 hours ago
$276
Roundtrip
found 2 hours ago
Select Copa flight, departing Sat, Sep 6 from Miami Intl. to Tocumen Intl., returning Wed, Sep 10, priced at $276 found 2 hours ago
Copa
Sat, Sep 6 - Wed, Sep 10
MIA
Miami Intl.
PTY
Tocumen Intl.
$286 Roundtrip, found 2 hours ago
$286
Roundtrip
found 2 hours ago
Select Copa flight, departing Sat, Sep 6 from Miami Intl. to Tocumen Intl., returning Wed, Sep 10, priced at $286 found 2 hours ago
Copa
Tue, Aug 26 - Thu, Sep 4
MIA
Miami Intl.
PTY
Tocumen Intl.
$290 Roundtrip, found 4 hours ago
$290
Roundtrip
found 4 hours ago
Select Copa flight, departing Tue, Aug 26 from Miami Intl. to Tocumen Intl., returning Thu, Sep 4, priced at $290 found 4 hours ago
Delta
Sat, Sep 6 - Wed, Sep 10
MIA
Miami Intl.
PTY
Tocumen Intl.
$290 Roundtrip, found 2 hours ago
$290
Roundtrip
found 2 hours ago
Select Delta flight, departing Sat, Sep 6 from Miami Intl. to Tocumen Intl., returning Wed, Sep 10, priced at $290 found 2 hours ago
Copa
Sat, Sep 6 - Wed, Sep 10
MIA
Miami Intl.
PTY
Tocumen Intl.
$296 Roundtrip, found 2 hours ago
$296
Roundtrip
found 2 hours ago
Select Copa flight, departing Sat, Sep 6 from Miami Intl. to Tocumen Intl., returning Wed, Sep 10, priced at $296 found 2 hours ago
Delta
Fri, Sep 5 - Thu, Sep 11
MIA
Miami Intl.
PTY
Tocumen Intl.
$297 Roundtrip, found 1 day ago
$297
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Sep 5 from Miami Intl. to Tocumen Intl., returning Thu, Sep 11, priced at $297 found 1 day ago
American Airlines
Thu, Oct 23 - Mon, Oct 27
MIA
Miami Intl.
PTY
Tocumen Intl.
$301 Roundtrip, found 3 days ago
$301
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 23 from Miami Intl. to Tocumen Intl., returning Mon, Oct 27, priced at $301 found 3 days ago
United
Thu, Oct 23 - Mon, Oct 27
MIA
Miami Intl.
PTY
Tocumen Intl.
$363 Roundtrip, found 3 days ago
$363
Roundtrip
found 3 days ago
Select United flight, departing Thu, Oct 23 from Miami Intl. to Tocumen Intl., returning Mon, Oct 27, priced at $363 found 3 days ago
avianca
Sat, Sep 6 - Wed, Sep 10
MIA
Miami Intl.
PTY
Tocumen Intl.
$417 Roundtrip, found 2 hours ago
$417
Roundtrip
found 2 hours ago
Select avianca flight, departing Sat, Sep 6 from Miami Intl. to Tocumen Intl., returning Wed, Sep 10, priced at $417 found 2 hours ago
Copa
Sat, Nov 1 - Sat, Nov 8
MCO
Orlando Intl.
PTY
Tocumen Intl.
$443 Roundtrip, found 6 days ago
$443
Roundtrip
found 6 days ago
Select Copa flight, departing Sat, Nov 1 from Orlando Intl. to Tocumen Intl., returning Sat, Nov 8, priced at $443 found 6 days ago
United
Mon, Dec 1 - Thu, Dec 18
SAT
San Antonio Intl.
PTY
Tocumen Intl.
$499 Roundtrip, found 1 day ago
$499
Roundtrip
found 1 day ago
Select United flight, departing Mon, Dec 1 from San Antonio Intl. to Tocumen Intl., returning Thu, Dec 18, priced at $499 found 1 day ago
Copa
Fri, Mar 13 - Mon, Mar 16
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$547 Roundtrip, found 6 hours ago
$547
Roundtrip
found 6 hours ago
Select Copa flight, departing Fri, Mar 13 from John F. Kennedy Intl. to Tocumen Intl., returning Mon, Mar 16, priced at $547 found 6 hours ago
American Airlines
Wed, Nov 19 - Wed, Nov 26
EWR
Newark Liberty Intl. Airport
PTY
Tocumen Intl.
$561 Roundtrip, found 3 days ago
$561
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Nov 19 from Newark Liberty Intl. Airport to Tocumen Intl., returning Wed, Nov 26, priced at $561 found 3 days ago
Copa
Wed, Dec 10 - Tue, Dec 16
KIN
Norman Manley Intl.
PTY
Tocumen Intl.
$583 Roundtrip, found 3 hours ago
$583
Roundtrip
found 3 hours ago
Select Copa flight, departing Wed, Dec 10 from Norman Manley Intl. to Tocumen Intl., returning Tue, Dec 16, priced at $583 found 3 hours ago
Copa
Mon, Dec 29 - Thu, Jan 1
ORD
O'Hare Intl.
PTY
Tocumen Intl.
$637 Roundtrip, found 6 days ago
$637
Roundtrip
found 6 days ago
Select Copa flight, departing Mon, Dec 29 from O'Hare Intl. to Tocumen Intl., returning Thu, Jan 1, priced at $637 found 6 days ago
Cayman Airways
Mon, Dec 15 - Thu, Dec 18
KIN
Norman Manley Intl.
PTY
Tocumen Intl.
$675 Roundtrip, found 3 hours ago
$675
Roundtrip
found 3 hours ago
Select Cayman Airways flight, departing Mon, Dec 15 from Norman Manley Intl. to Tocumen Intl., returning Thu, Dec 18, priced at $675 found 3 hours ago

Cheap Flights to Santa Clara

Fall in love at first flight with your vacation to Santa Clara by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Clara on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Clara, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Clara

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Clara with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PAC airport.

What is the cheapest month to fly to Santa Clara?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Clara are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Clara?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Clara.

What airport is best to fly into Santa Clara?

When you’re planning your trip to Santa Clara, convenience is the name of the game. Luckily, Santa Clara Panama Pacifico Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Clara must-do list.

How much are flights to Santa Clara?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Clara on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $276, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Clara?

The trick to saving a stack of cash on your flight to Santa Clara? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $276 right now, why wait?

Santa Clara Flight Information
Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Roundtrip price
$275

Last Minute Hotel Deals in Santa Clara

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (4,165 reviews)
"Staff was great!"

Reviewed on Aug 16, 2025

Get rates
Hotel Riu Plaza Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Stay at this 4-star spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located ...
9/10 Wonderful! (413 reviews)
"Nice hotel, lively lots of tourists/ music movement. convenient 24/7 coffee shop. walking distance from other restaurants/shops and night life"

Reviewed on Aug 15, 2025

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Waymore Hotel Spa & Casino
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.2/10 Good! (1,015 reviews)
"It was good"

Reviewed on Aug 17, 2025

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Dreams Playa Bonita Panama - All Inclusive
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111, Panama City, Panama
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.6/10 Good! (1,000 reviews)
"The hotel was very nice but we never did have hot water in the bathroom the whole time we were there."

Reviewed on Aug 8, 2025

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Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (926 reviews)
"El hotel es super lindo y el desayuno es muy bueno. La atención también excelente."

Reviewed on Aug 6, 2025

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Sheraton Grand Panama
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5 out of 5
Km 6 Road to Veracruz, Veracruz, Panama
Stay at this 5-star luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8/10 Very Good! (1,003 reviews)
"The grounds and common spaces were really nice. The rooms are spacious. Variety of food choices with the restuarants. Staff was friendly."

Reviewed on Aug 13, 2025

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The Westin Playa Bonita Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (1,021 reviews)
"Tienen Que tener kit de emergencia las 24 horas.. yo nesecite bendaje . Y me dijeron que la person que estaba a cargo de eso .. salio y que por lo menos tenia que esperar mas de 30 mnt."

Reviewed on Aug 16, 2025

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Megapolis Hotel Panamá
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,001 reviews)
"service 100/100"

Reviewed on Aug 9, 2025

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JW Marriott Panama
See all 1,487 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.