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Santa Clara

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Santa Clara Flights as Low as $297

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Thu, Jul 10 - Sat, Jul 12
LGA
LaGuardia
PTY
Tocumen Intl.
$297 Roundtrip, found 1 day ago
$297
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jul 10 from LaGuardia to Tocumen Intl., returning Sat, Jul 12, priced at $297 found 1 day ago
American Airlines
Mon, Jul 7 - Fri, Jul 11
LGA
LaGuardia
PTY
Tocumen Intl.
$300 Roundtrip, found 1 day ago
$300
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jul 7 from LaGuardia to Tocumen Intl., returning Fri, Jul 11, priced at $300 found 1 day ago
United
Mon, Aug 11 - Tue, Aug 19
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$363 Roundtrip, found 21 hours ago
$363
Roundtrip
found 21 hours ago
Select United flight, departing Mon, Aug 11 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Tue, Aug 19, priced at $363 found 21 hours ago
United
Wed, Aug 13 - Mon, Aug 18
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$372 Roundtrip, found 2 days ago
$372
Roundtrip
found 2 days ago
Select United flight, departing Wed, Aug 13 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Mon, Aug 18, priced at $372 found 2 days ago
American Airlines
Mon, Jul 7 - Mon, Jul 14
EWR
Newark Liberty Intl. Airport
PTY
Tocumen Intl.
$374 Roundtrip, found 1 day ago
$374
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jul 7 from Newark Liberty Intl. Airport to Tocumen Intl., returning Mon, Jul 14, priced at $374 found 1 day ago
United
Wed, Aug 13 - Mon, Aug 18
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$380 Roundtrip, found 2 days ago
$380
Roundtrip
found 2 days ago
Select United flight, departing Wed, Aug 13 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Mon, Aug 18, priced at $380 found 2 days ago
Delta
Mon, Sep 8 - Sun, Sep 28
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$397 Roundtrip, found 2 days ago
$397
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Sep 8 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Sun, Sep 28, priced at $397 found 2 days ago
Copa
Tue, Aug 12 - Mon, Aug 18
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$397 Roundtrip, found 21 hours ago
$397
Roundtrip
found 21 hours ago
Select Copa flight, departing Tue, Aug 12 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Mon, Aug 18, priced at $397 found 21 hours ago
United
Mon, Aug 11 - Mon, Aug 18
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$399 Roundtrip, found 21 hours ago
$399
Roundtrip
found 21 hours ago
Select United flight, departing Mon, Aug 11 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Mon, Aug 18, priced at $399 found 21 hours ago
Delta
Sat, Jul 5 - Sun, Jul 13
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$402 Roundtrip, found 1 day ago
$402
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jul 5 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Sun, Jul 13, priced at $402 found 1 day ago
Copa
Sun, Aug 17 - Mon, Aug 18
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$407 Roundtrip, found 21 hours ago
$407
Roundtrip
found 21 hours ago
Select Copa flight, departing Sun, Aug 17 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Mon, Aug 18, priced at $407 found 21 hours ago
United
Wed, Aug 13 - Mon, Aug 18
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$408 Roundtrip, found 2 days ago
$408
Roundtrip
found 2 days ago
Select United flight, departing Wed, Aug 13 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Mon, Aug 18, priced at $408 found 2 days ago
American Airlines
Mon, Jul 7 - Mon, Jul 14
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$438 Roundtrip, found 1 day ago
$438
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jul 7 from John F. Kennedy Intl. to Tocumen Intl., returning Mon, Jul 14, priced at $438 found 1 day ago
United
Wed, Jul 2 - Thu, Aug 7
SAT
San Antonio Intl.
PTY
Tocumen Intl.
$479 Roundtrip, just found
$479
Roundtrip
just found
Select United flight, departing Wed, Jul 2 from San Antonio Intl. to Tocumen Intl., returning Thu, Aug 7, priced at $479 just found
avianca
Thu, May 22 - Sun, May 25
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$489 Roundtrip, found 23 hours ago
$489
Roundtrip
found 23 hours ago
Select avianca flight, departing Thu, May 22 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Sun, May 25, priced at $489 found 23 hours ago
Copa
Sun, Sep 21 - Sat, Sep 27
POS
Piarco Intl.
PTY
Tocumen Intl.
$572 Roundtrip, found 1 day ago
$572
Roundtrip
found 1 day ago
Select Copa flight, departing Sun, Sep 21 from Piarco Intl. to Tocumen Intl., returning Sat, Sep 27, priced at $572 found 1 day ago

Cheap Flights to Santa Clara

Fall in love at first flight with your vacation to Santa Clara by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Clara on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Clara, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Clara

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Clara with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PAC airport.

What is the cheapest month to fly to Santa Clara?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Clara are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Clara?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Clara.

What airport is best to fly into Santa Clara?

When you’re planning your trip to Santa Clara, convenience is the name of the game. Luckily, Santa Clara Panama Pacifico Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Clara must-do list.

How much are flights to Santa Clara?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Clara on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $297, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Clara?

The trick to saving a stack of cash on your flight to Santa Clara? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $297 right now, why wait?

Santa Clara Flight Information
Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Roundtrip price
$297

Last Minute Hotel Deals in Santa Clara

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is $138 per night from Apr 29 to Apr 30
$138
includes taxes & fees
Apr 29 - Apr 30
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (3,865 reviews)
"It was safe, quiet, transportation excellent. Excellent, efficient staff consistency. Excellent dining service. Didn't like limited parking."

Reviewed on Apr 21, 2025

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
The price is $251 per night from May 17 to May 18
$251
includes taxes & fees
May 17 - May 18
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.4/10 Good! (1,003 reviews)
"I thought the customer service was great with all staff, and rooms were clean. Disappointed with the limited food option and the early closing hours of the pools and preferred lounge."

Reviewed on Apr 10, 2025

Dreams Playa Bonita Panama - All Inclusive
Riande Urban Hotel
Riande Urban Hotel
3.5 out of 5
El Cangrejo; Calle Eusebio A, Morales, Panama City, Panama
The price is $72 per night from Apr 23 to Apr 24
$72
includes taxes & fees
Apr 23 - Apr 24
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the bar and the helpful staff ...
8.6/10 Excellent! (1,007 reviews)
"Room was clean and guest were excellent. And the guest service was exceptional"

Reviewed on Apr 18, 2025

Riande Urban Hotel
JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is $202 per night from May 1 to May 2
$202
includes taxes & fees
May 1 - May 2
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,001 reviews)
"Everything about it was spectacular. Food was wonderful. Casino next door. Pool is fun. And the staff are pleasant."

Reviewed on Apr 13, 2025

JW Marriott Panama
The Westin Playa Bonita Panama
The Westin Playa Bonita Panama
5 out of 5
Km 6 Road to Veracruz, Veracruz, Panama
The price is $180 per night from May 5 to May 6
$180
includes taxes & fees
May 5 - May 6
Stay at this 5-star luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8/10 Very Good! (1,000 reviews)
"We loved our time staying at this beautiful resort. Everyone was so nice and welcoming. The service was fantastic. Beautiful and close to everything. I would recommend it to anyone!"

Reviewed on Apr 10, 2025

The Westin Playa Bonita Panama
Sheraton Grand Panama
Sheraton Grand Panama
4 out of 5
Via Israel And 77th Street, Panama City, Panama
The price is $149 per night from May 1 to May 2
$149
includes taxes & fees
May 1 - May 2
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (864 reviews)
5 Stars all the way
"This was simply put, an outstanding stay from start to finish. The staff were amazing, the room was clean, the housekeeping was always on time and helpful, just a wonderful experience for me and my 3 kids. We were on the club floor which was an extra special experience. These folks know what they ..."

Reviewed on Apr 6, 2025

Sheraton Grand Panama
Principe Hotel and Suites
Principe Hotel and Suites
3 out of 5
Via Argentina, Panama City, Panama
The price is $64 per night from Apr 23 to Apr 24
$64
includes taxes & fees
Apr 23 - Apr 24
Stay at this 3-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,315 reviews)
"Nice hotel. great staff"

Reviewed on Apr 19, 2025

Principe Hotel and Suites
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
The price is $156 per night from Apr 27 to Apr 28
$156
includes taxes & fees
Apr 27 - Apr 28
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (2,008 reviews)
"Pleasant hotel with a good breakfast buffet each morning. Also offered dinner buffets on some nights for a reasonable rate. Pool was great, just hard to get a towel in the evening. Nice staff and great view of the city from bayside rooms. Some noise from the nearby road and very limited restaurant ..."

Reviewed on Apr 20, 2025

Plaza Paitilla Inn Hotel
See all 1,394 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.