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Santa Clara

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Santa Clara Flights as Low as $214

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Sun, Aug 3 - Fri, Aug 15
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$214 Roundtrip, found 22 hours ago
$214
Roundtrip
found 22 hours ago
Select Copa flight, departing Sun, Aug 3 from Juan Santamaría Intl. to Tocumen Intl., returning Fri, Aug 15, priced at $214 found 22 hours ago
Copa
Fri, Aug 8 - Sat, Aug 9
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$219 Roundtrip, found 21 hours ago
$219
Roundtrip
found 21 hours ago
Select Copa flight, departing Fri, Aug 8 from Juan Santamaría Intl. to Tocumen Intl., returning Sat, Aug 9, priced at $219 found 21 hours ago
Copa
Mon, Jan 26 - Thu, Jan 29
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$224 Roundtrip, found 22 hours ago
$224
Roundtrip
found 22 hours ago
Select Copa flight, departing Mon, Jan 26 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jan 29, priced at $224 found 22 hours ago
avianca
Tue, Aug 5 - Tue, Aug 12
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$230 Roundtrip, found 12 hours ago
$230
Roundtrip
found 12 hours ago
Select avianca flight, departing Tue, Aug 5 from Juan Santamaría Intl. to Tocumen Intl., returning Tue, Aug 12, priced at $230 found 12 hours ago
Copa
Mon, Jan 26 - Thu, Jan 29
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$237 Roundtrip, found 22 hours ago
$237
Roundtrip
found 22 hours ago
Select Copa flight, departing Mon, Jan 26 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jan 29, priced at $237 found 22 hours ago
avianca
Tue, Aug 5 - Sun, Aug 17
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$238 Roundtrip, found 4 days ago
$238
Roundtrip
found 4 days ago
Select avianca flight, departing Tue, Aug 5 from Juan Santamaría Intl. to Tocumen Intl., returning Sun, Aug 17, priced at $238 found 4 days ago
Copa
Fri, Aug 8 - Sat, Aug 9
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$242 Roundtrip, found 21 hours ago
$242
Roundtrip
found 21 hours ago
Select Copa flight, departing Fri, Aug 8 from Juan Santamaría Intl. to Tocumen Intl., returning Sat, Aug 9, priced at $242 found 21 hours ago
Copa
Thu, Sep 18 - Tue, Sep 23
MIA
Miami Intl.
PTY
Tocumen Intl.
$349 Roundtrip, found 3 hours ago
$349
Roundtrip
found 3 hours ago
Select Copa flight, departing Thu, Sep 18 from Miami Intl. to Tocumen Intl., returning Tue, Sep 23, priced at $349 found 3 hours ago
American Airlines
Mon, Sep 15 - Mon, Sep 22
MIA
Miami Intl.
PTY
Tocumen Intl.
$349 Roundtrip, found 21 hours ago
$349
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Mon, Sep 15 from Miami Intl. to Tocumen Intl., returning Mon, Sep 22, priced at $349 found 21 hours ago
United
Sun, Sep 21 - Thu, Sep 25
MIA
Miami Intl.
PTY
Tocumen Intl.
$363 Roundtrip, found 3 hours ago
$363
Roundtrip
found 3 hours ago
Select United flight, departing Sun, Sep 21 from Miami Intl. to Tocumen Intl., returning Thu, Sep 25, priced at $363 found 3 hours ago
Delta
Mon, Sep 15 - Wed, Sep 24
MIA
Miami Intl.
PTY
Tocumen Intl.
$363 Roundtrip, found 3 hours ago
$363
Roundtrip
found 3 hours ago
Select Delta flight, departing Mon, Sep 15 from Miami Intl. to Tocumen Intl., returning Wed, Sep 24, priced at $363 found 3 hours ago
Copa
Thu, Oct 16 - Tue, Oct 21
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$393 Roundtrip, found 18 hours ago
$393
Roundtrip
found 18 hours ago
Select Copa flight, departing Thu, Oct 16 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Tue, Oct 21, priced at $393 found 18 hours ago
American Airlines
Sat, Sep 6 - Thu, Sep 11
BWI
Baltimore Washington Intl. Thurgood Marshall
PTY
Tocumen Intl.
$458 Roundtrip, found 17 hours ago
$458
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Sat, Sep 6 from Baltimore Washington Intl. Thurgood Marshall to Tocumen Intl., returning Thu, Sep 11, priced at $458 found 17 hours ago
Copa
Sun, Oct 19 - Thu, Nov 13
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$472 Roundtrip, found 4 hours ago
$472
Roundtrip
found 4 hours ago
Select Copa flight, departing Sun, Oct 19 from John F. Kennedy Intl. to Tocumen Intl., returning Thu, Nov 13, priced at $472 found 4 hours ago
American Airlines
Sat, Aug 23 - Thu, Nov 27
DCA
Ronald Reagan Washington National
PTY
Tocumen Intl.
$472 Roundtrip, found 1 day ago
$472
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Aug 23 from Ronald Reagan Washington National to Tocumen Intl., returning Thu, Nov 27, priced at $472 found 1 day ago
Aeromexico
Thu, Sep 18 - Tue, Sep 23
MIA
Miami Intl.
PTY
Tocumen Intl.
$699 Roundtrip, found 3 hours ago
$699
Roundtrip
found 3 hours ago
Select Aeromexico flight, departing Thu, Sep 18 from Miami Intl. to Tocumen Intl., returning Tue, Sep 23, priced at $699 found 3 hours ago

Cheap Flights to Santa Clara

Fall in love at first flight with your vacation to Santa Clara by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Clara on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Clara, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Clara

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Clara with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PAC airport.

What is the cheapest month to fly to Santa Clara?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Clara are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Clara?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Clara.

What airport is best to fly into Santa Clara?

When you’re planning your trip to Santa Clara, convenience is the name of the game. Luckily, Santa Clara Panama Pacifico Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Clara must-do list.

How much are flights to Santa Clara?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Clara on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $214, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Clara?

The trick to saving a stack of cash on your flight to Santa Clara? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $214 right now, why wait?

Santa Clara Flight Information
Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Roundtrip price
$213

Last Minute Hotel Deals in Santa Clara

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (4,123 reviews)
"It was amazing"

Reviewed on Jul 24, 2025

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Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.2/10 Good! (1,016 reviews)
"It is a nice resort for all type customers adults only or with family. located by the ocean , great scenery, very kind and nice staffs with good service ,away from the city with clean air quality."

Reviewed on Jul 24, 2025

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Dreams Playa Bonita Panama - All Inclusive
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (907 reviews)
"Food was good but not excellent ,bedrooms clean but in the tired side"

Reviewed on Jul 19, 2025

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Sheraton Grand Panama
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5 out of 5
Km 6 Road to Veracruz, Veracruz, Panama
Stay at this 5-star luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8/10 Very Good! (1,006 reviews)
"Love it i would go back"

Reviewed on Jul 21, 2025

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The Westin Playa Bonita Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Stay at this 4-star spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located ...
9/10 Wonderful! (363 reviews)
"The property itself was nice, but I just had a few things that annoyed me. As soon as we got there, the television wasn't working. They got someone up there to check it, but he left saying he would return. He never did. The next day I stopped at the desk on my way out and told them. When I returned, ..."

Reviewed on Jul 23, 2025

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Waymore Hotel Spa & Casino
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111, Panama City, Panama
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.6/10 Good! (1,006 reviews)
"Staff was great! Front desk agent Christian very nice and friendly! Breakfast was nice and restaurant staff always very helpful."

Reviewed on Jul 20, 2025

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Hotel El Panama by Faranda Grand, a member of Radisson Individuals
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,006 reviews)
JW Marriott Experience
"The hotel was spotless, and the staff were friendly. It's a bit expensive, as I was expecting more of a luxury hotel. The only bad thing was the breakfast one morning, when everything was cold and the cup of coffee wasn't hot. The toast was hard as a rock, so it was a total disappointment for the ..."

Reviewed on Jul 18, 2025

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JW Marriott Panama
Ramada Plaza By Wyndham Panama Punta Pacífica

Ramada Plaza By Wyndham Panama Punta Pacífica

4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,010 reviews)
"Everything was perfect"

Reviewed on Jul 25, 2025

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Ramada Plaza By Wyndham Panama Punta Pacífica
See all 1,456 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.