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Santa Clara

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Santa Clara Flights as Low as $433

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Feb 12 - Fri, Feb 14
MCO
Orlando Intl.
PTY
Tocumen Intl.
$433 Roundtrip, found 1 day ago
$433
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Feb 12 from Orlando Intl. to Tocumen Intl., returning Fri, Feb 14, priced at $433 found 1 day ago
American Airlines
Wed, Feb 12 - Fri, Feb 14
MCO
Orlando Intl.
PTY
Tocumen Intl.
$440 Roundtrip, found 1 day ago
$440
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Feb 12 from Orlando Intl. to Tocumen Intl., returning Fri, Feb 14, priced at $440 found 1 day ago
Copa
Thu, Mar 27 - Sun, Mar 30
MCO
Orlando Intl.
PTY
Tocumen Intl.
$467 Roundtrip, found 2 days ago
$467
Roundtrip
found 2 days ago
Select Copa flight, departing Thu, Mar 27 from Orlando Intl. to Tocumen Intl., returning Sun, Mar 30, priced at $467 found 2 days ago
Copa
Thu, Mar 27 - Sun, Mar 30
MCO
Orlando Intl.
PTY
Tocumen Intl.
$477 Roundtrip, found 2 days ago
$477
Roundtrip
found 2 days ago
Select Copa flight, departing Thu, Mar 27 from Orlando Intl. to Tocumen Intl., returning Sun, Mar 30, priced at $477 found 2 days ago
Copa
Thu, Mar 27 - Sun, Mar 30
MCO
Orlando Intl.
PTY
Tocumen Intl.
$487 Roundtrip, found 2 days ago
$487
Roundtrip
found 2 days ago
Select Copa flight, departing Thu, Mar 27 from Orlando Intl. to Tocumen Intl., returning Sun, Mar 30, priced at $487 found 2 days ago
American Airlines
Wed, Feb 12 - Fri, Feb 14
MCO
Orlando Intl.
PTY
Tocumen Intl.
$488 Roundtrip, found 1 day ago
$488
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Feb 12 from Orlando Intl. to Tocumen Intl., returning Fri, Feb 14, priced at $488 found 1 day ago
Delta
Fri, Mar 28 - Tue, Apr 1
MCO
Orlando Intl.
PTY
Tocumen Intl.
$495 Roundtrip, found 2 days ago
$495
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Mar 28 from Orlando Intl. to Tocumen Intl., returning Tue, Apr 1, priced at $495 found 2 days ago
American Airlines
Wed, Feb 12 - Thu, Feb 20
MCO
Orlando Intl.
PTY
Tocumen Intl.
$513 Roundtrip, found 8 hours ago
$513
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Feb 12 from Orlando Intl. to Tocumen Intl., returning Thu, Feb 20, priced at $513 found 8 hours ago
United
Sat, Jun 7 - Tue, Jun 10
MCO
Orlando Intl.
PTY
Tocumen Intl.
$533 Roundtrip, found 5 days ago
$533
Roundtrip
found 5 days ago
Select United flight, departing Sat, Jun 7 from Orlando Intl. to Tocumen Intl., returning Tue, Jun 10, priced at $533 found 5 days ago
Delta
Mon, Mar 3 - Thu, Mar 13
BDL
Bradley Intl.
PTY
Tocumen Intl.
$541 Roundtrip, found 11 hours ago
$541
Roundtrip
found 11 hours ago
Select Delta flight, departing Mon, Mar 3 from Bradley Intl. to Tocumen Intl., returning Thu, Mar 13, priced at $541 found 11 hours ago
avianca
Wed, Feb 12 - Mon, Feb 17
MCO
Orlando Intl.
PTY
Tocumen Intl.
$559 Roundtrip, found 1 day ago
$559
Roundtrip
found 1 day ago
Select avianca flight, departing Wed, Feb 12 from Orlando Intl. to Tocumen Intl., returning Mon, Feb 17, priced at $559 found 1 day ago
American Airlines
Wed, Mar 12 - Tue, Mar 18
FSD
Sioux Falls Regional
PTY
Tocumen Intl.
$566 Roundtrip, found 8 hours ago
$566
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Mar 12 from Sioux Falls Regional to Tocumen Intl., returning Tue, Mar 18, priced at $566 found 8 hours ago
Copa
Wed, Feb 19 - Wed, Feb 26
BWI
Baltimore Washington Intl. Thurgood Marshall
PTY
Tocumen Intl.
$597 Roundtrip, found 6 days ago
$597
Roundtrip
found 6 days ago
Select Copa flight, departing Wed, Feb 19 from Baltimore Washington Intl. Thurgood Marshall to Tocumen Intl., returning Wed, Feb 26, priced at $597 found 6 days ago
Delta
Mon, Mar 17 - Tue, Mar 25
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$623 Roundtrip, found 2 days ago
$623
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Mar 17 from John F. Kennedy Intl. to Tocumen Intl., returning Tue, Mar 25, priced at $623 found 2 days ago
Delta
Tue, Feb 25 - Tue, Mar 4
EWR
Newark Liberty Intl. Airport
PTY
Tocumen Intl.
$643 Roundtrip, found 4 days ago
$643
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Feb 25 from Newark Liberty Intl. Airport to Tocumen Intl., returning Tue, Mar 4, priced at $643 found 4 days ago
American Airlines
Fri, Nov 28 - Fri, Dec 5
MSP
Minneapolis - St. Paul Intl.
PTY
Tocumen Intl.
$664 Roundtrip, found 5 days ago
$664
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Nov 28 from Minneapolis - St. Paul Intl. to Tocumen Intl., returning Fri, Dec 5, priced at $664 found 5 days ago

Cheap Flights to Santa Clara

Fall in love at first flight with your vacation to Santa Clara by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Clara on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Clara, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Clara

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Clara with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PAC airport.

What is the cheapest month to fly to Santa Clara?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Clara are in February, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Clara?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Clara.

What airport is best to fly into Santa Clara?

When you’re planning your trip to Santa Clara, convenience is the name of the game. Luckily, Santa Clara Panama Pacifico Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Clara must-do list.

How much are flights to Santa Clara?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Clara on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $433, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Clara?

The trick to saving a stack of cash on your flight to Santa Clara? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $433 right now, why wait?

Santa Clara Flight Information
Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Roundtrip price
$433

Last Minute Hotel Deals in Santa Clara

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is $131 per night from Feb 26 to Feb 27
$131
includes taxes & fees
Feb 26 - Feb 27
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (3,556 reviews)
"Very professional and friendly staff."

Reviewed on Jan 26, 2025

Hotel Riu Plaza Panama
Waldorf Astoria Panama
Waldorf Astoria Panama
5 out of 5
47th St. & Uruguay Street, Panama City, Panama
The price is $166 per night from Feb 28 to Mar 1
$166
includes taxes & fees
Feb 28 - Mar 1
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,001 reviews)
"Loved it and great service . Will return"

Reviewed on Jan 17, 2025

Waldorf Astoria Panama
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
The price is $129 per night from Jan 30 to Jan 31
$129
includes taxes & fees
Jan 30 - Jan 31
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (1,810 reviews)
"It's right on the lengthy seawall and you can walk to Casco Viejo from the hotel if you want and the nearby shopping."

Reviewed on Jan 28, 2025

Plaza Paitilla Inn Hotel
Dreams Playa Bonita Panama - All Inclusive
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
The price is $381 per night from Feb 4 to Feb 5
$381
includes taxes & fees
Feb 4 - Feb 5
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.4/10 Good! (1,006 reviews)
"It was a little far away from downtown Panama city which to me was great. Everything about this place was beautiful."

Reviewed on Jan 24, 2025

Dreams Playa Bonita Panama - All Inclusive
Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
The price is $90 per night from Jan 31 to Feb 1
$90
includes taxes & fees
Jan 31 - Feb 1
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,019 reviews)
"Wonderful breakfast"

Reviewed on Jan 26, 2025

Decapolis Hotel Panama City
W Panama
W Panama
5 out of 5
Calle Aquilino de la Guardia & Calle 50, Bella Vista, Panama City
The price is $158 per night from Mar 1 to Mar 2
$158
includes taxes & fees
Mar 1 - Mar 2
Stay at this 5-star luxury hotel in Panama City. Enjoy 2 restaurants, 3 spa tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,004 reviews)
"Staffs on the site are very helpful and kind good customer service"

Reviewed on Jan 25, 2025

W Panama
The Westin Playa Bonita Panama
The Westin Playa Bonita Panama
5 out of 5
Km 6 Road to Veracruz, Veracruz, Panama
The price is $202 per night from Feb 28 to Mar 1
$202
includes taxes & fees
Feb 28 - Mar 1
Stay at this 5-star luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8/10 Very Good! (1,005 reviews)
"The staff is amazing, especially Jorge, Rennie, and Maria. It’s a lovely hotel, linens, bed, bathroom, balcony, all wonderful. AC works well. Oregano and Starfish grill were great, coffee was excellent."

Reviewed on Jan 24, 2025

The Westin Playa Bonita Panama
JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is $241 per night from Feb 27 to Feb 28
$241
includes taxes & fees
Feb 27 - Feb 28
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,001 reviews)
"It was great hotel. 15 mins to all attractions with Uber. The staff and service were amazing. Great breakfast buffet and other dining options. The furnitures in the rooms were not 5 star quality. There were a lot of kids in the pool area."

Reviewed on Jan 27, 2025

JW Marriott Panama
See all 1,317 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.