Hotels Near
Santa Ana

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Featured Santa Ana Hotels

Casco View Apartments
Casco View Apartments
3 out of 5
C. 16 Oeste, Panama City, Provincia de Panamá
Stay at this 3-star condo in Panama City. Enjoy free WiFi, premium bedding, and in-room washers/dryers. Popular attractions Albrook Shopping Mall and Cinta Costera ...
9.4/10 Exceptional! (33 reviews)
"I loved the location , apartment was nice and spacious. Manager was very attentive and the safety of the building was amazing . Even enjoyed a few of the soccer games on the corner"

Reviewed on May 27, 2025

Casco View Apartments
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (3,964 reviews)
RIU PLAZA Panama
"I really enjoyed my time there, breakfast was amazing"

Reviewed on May 30, 2025

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Fully refundable
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
8.4/10 Very Good! (2,120 reviews)
"Crowne Plaza PTY was a terrific and welcome find - the staff was courteous an ands very helpful, the shuttle was in perfect condition (with a very helpful driver) and the restaurant buffet was delicious. It’s 0.2 mi from the airport with a very reliable shuttle running on the hour. A strong ..."

Reviewed on May 23, 2025

Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.4/10 Good! (1,008 reviews)
"Overall I had a great time and a great experience at this resort. The pros are that we stayed in a deluxe preferred room which gave us access to the preferred pool which was adults only. The service from Eric the bartender was fantastic! And the service from the gentleman at the poolside snack bar ..."

Reviewed on May 30, 2025

Dreams Playa Bonita Panama - All Inclusive
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
4 out of 5
Via Espana 111, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.6/10 Good! (999 reviews)
"Good service..!"

Reviewed on May 29, 2025

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,000 reviews)
"Excelente atención en cualquier área visitada, gran profesionalismo ( A ) , para repetir el hotel"

Reviewed on May 26, 2025

JW Marriott Panama
The Westin Playa Bonita Panama
The Westin Playa Bonita Panama
5 out of 5
Km 6 Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8/10 Very Good! (1,000 reviews)
"Very clean hotel. Amazing staff. Great location away from the city but close enough if you want to go there. Wonderful ocean & jungle views."

Reviewed on May 24, 2025

The Westin Playa Bonita Panama
Riande Urban Hotel
Riande Urban Hotel
3.5 out of 5
El Cangrejo; Calle Eusebio A, Morales, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the bar and the helpful staff ...
8.6/10 Excellent! (1,003 reviews)
"For good location, cleanliness, staff and price"

Reviewed on May 20, 2025

Riande Urban Hotel
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (2,032 reviews)
"It was a great location, the hotel needs renovation, food area not good nobody answer to a call for a room service i had to come down and ask for a salad that was terrible and breakfast not really healthy options."

Reviewed on May 26, 2025

Plaza Paitilla Inn Hotel
Ramada Plaza By Wyndham Panama Punta Pacífica
Ramada Plaza By Wyndham Panama Punta Pacífica
4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,007 reviews)
"Nice place to land in Panama City. Centrally located, good service, nice breakfasts"

Reviewed on May 27, 2025

Ramada Plaza By Wyndham Panama Punta Pacífica
Waldorf Astoria Panama
Waldorf Astoria Panama
5 out of 5
47th St. & Uruguay Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,001 reviews)
"This place was amazing I loved it! The staff was amazing and the place well taken care by of."

Reviewed on May 11, 2025

Waldorf Astoria Panama
TRYP by Wyndham Panamá Centro
TRYP by Wyndham Panamá Centro
3.5 out of 5
Via Veneto, El Cangrejo Bellavista, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,001 reviews)
"Good for the price"

Reviewed on May 30, 2025

TRYP by Wyndham Panamá Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santa Ana

Panama City is a city that has a lot going on, but you have your sights set on Santa Ana. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santa Ana has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santa Ana hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Panama City so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santa Ana underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santa Ana city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santa Ana cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santa Ana at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $92
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santa Ana hotel you want, book it, and never look back. Because your great escape is ahead of you.