Hotels Near
Santa Ana

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Featured Santa Ana Hotels

Casco View Apartments
Casco View Apartments
3 out of 5
C. 16 Oeste, Panama City, Provincia de Panamá
Stay at this 3-star condo in Panama City. Enjoy free WiFi, premium bedding, and in-room washers/dryers. Popular attractions Albrook Shopping Mall and Cinta Costera ...
9.4/10 Exceptional! (24 reviews)
"Great accommodations. Great view. Great host."

Reviewed on Mar 21, 2025

Casco View Apartments
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (3,787 reviews)
"City Center"

Reviewed on Mar 27, 2025

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Fully refundable
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
8.4/10 Very Good! (2,084 reviews)
"Great hotel with great views. Not a lot to do around the area or eat"

Reviewed on Mar 28, 2025

Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.4/10 Good! (1,005 reviews)
"Very good"

Reviewed on Mar 28, 2025

Dreams Playa Bonita Panama - All Inclusive
Principe Hotel and Suites
Principe Hotel and Suites
3 out of 5
Via Argentina, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,290 reviews)
"Great place to stay , close to subway and via Argentina"

Reviewed on Mar 23, 2025

Principe Hotel and Suites
Riande Urban Hotel
Riande Urban Hotel
3.5 out of 5
El Cangrejo; Calle Eusebio A, Morales, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the bar and the helpful staff ...
8.6/10 Excellent! (1,011 reviews)
"Nice modern hotel near the city centre with a supermarket and numerous restaurants nearby. The food at the onsite Biergarten was not bad, but the included buffet breakfast was somewhat limited - cereal, fruit and a couple of hot options. Rooms are spacious but my bathroom was a bit of a squeeze. ..."

Reviewed on Mar 28, 2025

Riande Urban Hotel
Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,121 reviews)
Just as described
"Fantastic stay. Clean and front desk person was great with providing details about places to visit."

Reviewed on Mar 25, 2025

Decapolis Hotel Panama City
Marriott Panama Hotel
Marriott Panama Hotel
4 out of 5
Roosevelt Ave., Allbrook Mall, Panama City, Panama
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,010 reviews)
"The property is close to the city but outside and has great views of the skyline in the distance plus some beautiful countryside . Also good access to the Airport PTY"

Reviewed on Mar 28, 2025

Marriott Panama Hotel
W Panama
W Panama
5 out of 5
Calle Aquilino de la Guardia & Calle 50, Bella Vista, Panama City
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,001 reviews)
"Amazinggg place ! Def would book again"

Reviewed on Mar 21, 2025

W Panama
The Westin Playa Bonita Panama
The Westin Playa Bonita Panama
5 out of 5
Km 6 Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8/10 Very Good! (1,003 reviews)
"The hotel itself was lovely and the pools were great. I loved being on the ocean, but the beach itself was not very good. The resort was at least a 20 minute drive from the city, and the traffic over the Puente de las Americas was awful during rush hour The resort is also somewhat remote. I wanted ..."

Reviewed on Mar 25, 2025

The Westin Playa Bonita Panama
JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,003 reviews)
"Love the staff"

Reviewed on Mar 24, 2025

JW Marriott Panama
Riande Aeropuerto Hotel & Casino
Riande Aeropuerto Hotel & Casino
4 out of 5
Vía Tocumen, Entrance to Corredor Sur, Tocumen, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.4/10 Very Good! (1,802 reviews)
"Convenient to airport"

Reviewed on Mar 26, 2025

Riande Aeropuerto Hotel & Casino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santa Ana

Panama City is a city that has a lot going on, but you have your sights set on Santa Ana. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santa Ana has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santa Ana hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Panama City so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santa Ana underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santa Ana city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santa Ana cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santa Ana at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $64
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santa Ana hotel you want, book it, and never look back. Because your great escape is ahead of you.