Search for Cheap Deals on
Hotels in Carlisle

Check Last Minute Carlisle Hotel Deals

Tonight Jan 24 - Jan 25Next weekend Jan 30 - Feb 1

Choose from 55 Carlisle Hotel Deals

Holiday Inn Express & Suites Newberry by IHG

Holiday Inn Express & Suites Newberry by IHG

2.5 out of 5
121 Truman Ave Newberry SC
  • 13 min drive from Newberry Opera House
Book a stay at this business-friendly hotel in Newberry. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (645 reviews)
The room was clean and very cozy. Every member of the staff we came in contact with was very pleasant, professional, and helpful. The breakfast was awesome and I would definitely stay here again.

Reviewed on Jan 23, 2026

Holiday Inn Express & Suites Newberry by IHG
Quality Inn Clinton - Laurens I-26

Quality Inn Clinton - Laurens I-26

2.5 out of 5
105 Trade St Clinton SC
  • 55 min drive from Newberry Opera House
Book a stay at this business-friendly hotel in Clinton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (521 reviews)
Yes

Reviewed on Jan 15, 2026

Quality Inn Clinton - Laurens I-26
Hampton Inn Newberry-Opera House

Hampton Inn Newberry-Opera House

2.5 out of 5
1201 Nance St Newberry SC
  • 1 min walk from Newberry Opera House
Stay at this hotel in Newberry. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Memorial ...
8.8/10 Excellent! (809 reviews)
Most welcoming, friendly staff. Very clean room and lobby.

Reviewed on Jan 18, 2026

Hampton Inn Newberry-Opera House
Days Inn by Wyndham Clinton / Laurens I-26

Days Inn by Wyndham Clinton / Laurens I-26

2 out of 5
12374 Highway 56 N Clinton SC
  • 55 min drive from Newberry Opera House
Book a stay at this business-friendly motel in Clinton. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Josh and Ella Savage Park and ...
6.6/10 (420 reviews)
Cleanliness

Reviewed on Jan 1, 2026

Days Inn by Wyndham Clinton / Laurens I-26
Motel 6 Richburg, SC

Motel 6 Richburg, SC

2 out of 5
2912 Parkway Blvd Chester SC
  • 2 hours drive from Newberry Opera House
Stay at this motel in Chester. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews.
6.8/10 (344 reviews)
Yes

Reviewed on Jan 16, 2026

Motel 6 Richburg, SC
Hampton Inn & Suites Clinton - I-26

Hampton Inn & Suites Clinton - I-26

2.5 out of 5
201 E Corporate Center Drive Clinton SC
  • 52 min drive from Newberry Opera House
Book a stay at this business-friendly hotel in Clinton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (704 reviews)
We had a great room, spotless room, very quiet.

Reviewed on Jan 12, 2026

Hampton Inn & Suites Clinton - I-26
Days Inn by Wyndham Richburg

Days Inn by Wyndham Richburg

2 out of 5
3217 Lancaster Hwy Richburg SC
  • 2 hours drive from Newberry Opera House
Stay at this motel in Richburg. Enjoy free breakfast, free WiFi, and free parking.
7/10 Good! (555 reviews)
Clean , great staff

Reviewed on Jan 18, 2026

Days Inn by Wyndham Richburg
Holiday Inn Express Richburg by IHG

Holiday Inn Express Richburg by IHG

2.5 out of 5
3190 COMMERCE DRIVE Richburg SC
  • 2 hours drive from Newberry Opera House
Stay at this hotel in Richburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews.
9/10 Wonderful! (650 reviews)
It was good

Reviewed on Jan 16, 2026

Holiday Inn Express Richburg by IHG
Baymont by Wyndham Richburg/Chester Area

Baymont by Wyndham Richburg/Chester Area

2 out of 5
3085 Lancaster Hwy Richburg SC
  • 2 hours drive from Newberry Opera House
Book a stay at this business-friendly motel in Richburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (390 reviews)
Staff during my check in and out was great! I don't know what they are paid but management should give them a raise! Was very surprised at how comfortable my stay was, can't find that at this price point very often these days

Reviewed on Jan 17, 2026

Baymont by Wyndham Richburg/Chester Area
Quality Inn Union US Hwy 176

Quality Inn Union US Hwy 176

2.5 out of 5
315 N Duncan Byp Union SC
  • 1 hour drive from Newberry Opera House
Book a stay at this business-friendly hotel in Union. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our reviews. ...
7.4/10 Good! (252 reviews)
Not crazy about breakfast. Room was very nice and staff was nice to

Reviewed on Dec 26, 2025

Quality Inn Union US Hwy 176
Comfort Suites Clinton near Presbyterian College

Comfort Suites Clinton near Presbyterian College

2.5 out of 5
12865 Hwy 56 N Clinton SC
  • 55 min drive from Newberry Opera House
Book a stay at this business-friendly hotel in Clinton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (755 reviews)
The hotel is nice. The room was large and spacious even with 2 beds. The room was clean and the beds were soft. It was very quite, it didn't seem that many people were there by the few cars in the parking lot. The pool was not open as stated in some other reviews. They have a Continental breakfast, ...

Reviewed on Jan 15, 2026

Comfort Suites Clinton near Presbyterian College
Americas Best Value Inn Winnsboro, SC

Americas Best Value Inn Winnsboro, SC

2 out of 5
1894 US Highway 321 Bypass South Winnsboro SC
  • 1 hour drive from Newberry Opera House
Book a stay at this business-friendly motel in Winnsboro. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Historic Winnsboro Town Clock ...
5.8/10 (132 reviews)
yes

Reviewed on Oct 21, 2025

Americas Best Value Inn Winnsboro, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Carlisle

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Carlisle hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Carlisle.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Carlisle’s 55 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $61. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Carlisle hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Carlisle. No matter your reason for visiting Carlisle, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Carlisle hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Carlisle for as low as $61.

How many hotels are there in Carlisle?

With over 55 hotels in Carlisle, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $61.

How to find cheap car rentals in Carlisle?

Finding a cheap car rental deal in Carlisle is as easy as scoring cheap hotels in Carlisle. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.