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Hotels in Upstate South Carolina

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Last Minute Hot Rate® Hotel Deals in Upstate South Carolina

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Choose from 2477 Upstate South Carolina Hotel Deals

Days Inn by Wyndham Anderson
Days Inn by Wyndham Anderson
2 out of 5
1007 George Smith Mill Rd, Anderson, SC
  • 28 min drive from Clemson University
The price is $59 per night from Jun 30 to Jul 1
$59
per night
Jun 30 - Jul 1
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (754 reviews)
"The shower was nice"

Reviewed on Jun 22, 2024

Days Inn by Wyndham Anderson
Hilton Greenville
Hilton Greenville
3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
  • 1 hour drive from Clemson University
The price is $89 per night from Jul 2 to Jul 3
$89
per night
Jul 2 - Jul 3
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8/10 Very Good! (1,005 reviews)
"The room could have been a little updated. The toilet paper holder was rusty and carpet not very clean. The room was non smoking but smelled of smoke. Toilet was not clean under rim."

Reviewed on Jun 19, 2024

Hilton Greenville
Hotel Hartness
Hotel Hartness
4 out of 5
120 Halston Avenue, Greenville, SC
  • 2 hours drive from Clemson University
The price is $151 per night from Jun 30 to Jul 1
$151
per night
Jun 30 - Jul 1
Stay at this 4-star spa hotel in Greenville. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (234 reviews)
"The two evenong restaurant options had a very limited menu for this type of resort/hotel. Also, while I informed staff in advance of medical dietary restrictions, nothing was done in preparation for our reservations--including marking which items were safe for me to eat or could be made safe with ..."

Reviewed on Jun 23, 2024

Hotel Hartness
Hyatt Regency Greenville
Hyatt Regency Greenville
3.5 out of 5
220 N Main St, Greenville, SC
  • 1 hour drive from Clemson University
The price is $161 per night from Jun 24 to Jun 25
$161
per night
Jun 24 - Jun 25
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, an outdoor pool, and 2 bars/lounges. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,004 reviews)
"Nice place"

Reviewed on Jun 23, 2024

Hyatt Regency Greenville
La Quinta Inn & Suites by Wyndham Greenville Haywood
La Quinta Inn & Suites by Wyndham Greenville Haywood
2.5 out of 5
65 W Orchard Park Dr, Greenville, SC
  • 1 hour drive from Clemson University
The price is $77 per night from Jul 14 to Jul 15
$77
per night
Jul 14 - Jul 15
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,003 reviews)
"cn"

Reviewed on Jun 20, 2024

La Quinta Inn & Suites by Wyndham Greenville Haywood
Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & Suites
2.5 out of 5
831 Congaree Rd, Greenville, SC
  • 1 hour drive from Clemson University
The price is $89 per night from Jun 30 to Jul 1
$89
per night
Jun 30 - Jul 1
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,235 reviews)
"Great stay"

Reviewed on Jun 18, 2024

Best Western Plus Greenville I-385 Inn & Suites
Comfort Inn Greenville - Haywood Mall
Comfort Inn Greenville - Haywood Mall
2.5 out of 5
246 Congaree Road, Greenville, SC
  • 1 hour drive from Clemson University
The price is $80 per night from Jul 17 to Jul 18
$80
per night
Jul 17 - Jul 18
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,005 reviews)
I would definitely stay here again!
"Great place to stay for my family. Very clean and up-to-date. Good wi-fi. Convenient location. Good value."

Reviewed on Jun 21, 2024

Comfort Inn Greenville - Haywood Mall
Urban Boutique Hotel, BW Signature Collection
Urban Boutique Hotel, BW Signature Collection
2.5 out of 5
536 Wade Hampton Blvd, Greenville, SC
  • 1 hour drive from Clemson University
The price is $65 per night from Jun 30 to Jul 1
$65
per night
Jun 30 - Jul 1
Stay at this motel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
7.8/10 Good! (673 reviews)
"Had a nice stay. Clean nice rooms and the owner was very helpful when needed help. Breakfast was excellent"

Reviewed on Jun 17, 2024

Urban Boutique Hotel, BW Signature Collection
Midtown Suites-Greenville
Midtown Suites-Greenville
2.5 out of 5
11 Ketron Court, Greenville, SC
  • 1 hour drive from Clemson University
The price is $80 per night from Jul 1 to Jul 2
$80
per night
Jul 1 - Jul 2
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, a 24-hour front desk, and a 24-hour business center. Our guests praise the helpful ...
8.4/10 Very Good! (1,001 reviews)
"This property was a surprise excellent find for our overnight stay in Greenville South Carolina. It was in a quiet location about 1 block from everything. Check in was a breeze when booked via Expedia app. Room was large with a queen bed, recliner, kitchenette, large TV and a stocked bathroom. I ..."

Reviewed on Jun 9, 2024

Midtown Suites-Greenville
Aloft Greenville Downtown
Aloft Greenville Downtown
3 out of 5
5 North Laurens Street, Greenville, SC
  • 1 hour drive from Clemson University
The price is $122 per night from Jun 30 to Jul 1
$122
per night
Jun 30 - Jul 1
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,003 reviews)
"We love the Aloft Greenville! Our pups got star treatment and our room was great, a welcome retreat from the busyness of downtown. Hotel is in a great location with an easy walk to all the restaurants and shops."

Reviewed on Jun 22, 2024

Aloft Greenville Downtown
Hyatt Place Greenville/Downtown
Hyatt Place Greenville/Downtown
3 out of 5
128 East Broad Street, Greenville, SC
  • 1 hour drive from Clemson University
The price is $134 per night from Jun 30 to Jul 1
$134
per night
Jun 30 - Jul 1
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (1,001 reviews)
"The value for this property is tops! The breakfast and the cleanliness were impressive."

Reviewed on Jun 16, 2024

Hyatt Place Greenville/Downtown
Grand Bohemian Lodge Greenville, Autograph Collection
Grand Bohemian Lodge Greenville, Autograph Collection
4 out of 5
44 EAST CAMPERDOWN WAY, Greenville, SC
  • 1 hour drive from Clemson University
The price is $269 per night from Jun 30 to Jul 1
$269
per night
Jun 30 - Jul 1
Stay at this 4-star spa hotel in Greenville. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9.4/10 Exceptional! (199 reviews)
"We had a an amazing time! We travel with our pup and everyone at the hotel was so kind and friendly. We will be back!"

Reviewed on Jun 19, 2024

Grand Bohemian Lodge Greenville, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Upstate South Carolina

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Upstate South Carolina hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Upstate South Carolina.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Upstate South Carolina’s 2,477 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $59. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Upstate South Carolina hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Upstate South Carolina. No matter your reason for visiting Upstate South Carolina, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Upstate South Carolina hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Upstate South Carolina for as low as $59.

How many hotels are there in Upstate South Carolina?

With over 2,477 hotels in Upstate South Carolina, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $59.

How to find cheap car rentals in Upstate South Carolina?

Finding a cheap car rental deal in Upstate South Carolina is as easy as scoring cheap hotels in Upstate South Carolina. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Upstate South Carolina now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Upstate South Carolina right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.