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![3.5-star Hotel in Hendersonville](https://ak-secure.hotwirestatic.com/current/static/images/hotel/flex/deals/3.5star/2.jpg)
3.5-star Hotel
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![3.5-star Hotel in Hendersonville](https://ak-secure.hotwirestatic.com/current/static/images/hotel/flex/deals/3.5star/3.jpg)
3.5-star Hotel
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![3-star Hotel in Hendersonville](https://ak-secure.hotwirestatic.com/current/static/images/hotel/flex/deals/3.0star/1.jpg)
3-star Hotel
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![3-star Hotel in Hendersonville](https://ak-secure.hotwirestatic.com/current/static/images/hotel/flex/deals/3.0star/2.jpg)
3-star Hotel
Choose from 2477 Upstate South Carolina Hotel Deals
![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/fbd6c4b4_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 22, 2024
![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/7e931364_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 19, 2024
![Hotel Hartness](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 23, 2024
![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/w3839h2532x0y0-ab0b0705_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 23, 2024
![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/e263479f_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 20, 2024
![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/ca99d7c9_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 18, 2024
![Comfort Inn Greenville - Haywood Mall](https://images.trvl-media.com/lodging/1000000/30000/25000/24994/e1ac95e3_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 21, 2024
![Urban Boutique Hotel, BW Signature Collection](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/43fe68a7_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 17, 2024
![Midtown Suites-Greenville](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/w1262h720x9y0-80a1b766_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 9, 2024
![Aloft Greenville Downtown](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/02473870_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 22, 2024
![Hyatt Place Greenville/Downtown](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/b14b285d_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 16, 2024
![Grand Bohemian Lodge Greenville, Autograph Collection](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-5a1aa6df_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 19, 2024
Find cheap hotels in Upstate South Carolina
You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Upstate South Carolina hotel with Hotwire to complete your one-of-a-kind travel checklist.
For you, intrepid voyager, Hotwire has a large selection of the best hotels in Upstate South Carolina.
Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Upstate South Carolina’s 2,477 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $59. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Upstate South Carolina hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Upstate South Carolina. No matter your reason for visiting Upstate South Carolina, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Upstate South Carolina hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Upstate South Carolina for as low as $59.
How many hotels are there in Upstate South Carolina?
With over 2,477 hotels in Upstate South Carolina, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $59.
How to find cheap car rentals in Upstate South Carolina?
Finding a cheap car rental deal in Upstate South Carolina is as easy as scoring cheap hotels in Upstate South Carolina. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.
Is it safe to travel to Upstate South Carolina now?
With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Upstate South Carolina right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.
Top Booked Hotels in Upstate South Carolina
- Hilton Greenville
- Hyatt Regency Greenville
- La Quinta Inn & Suites by Wyndham Greenville Haywood
- Best Western Plus Greenville I-385 Inn & Suites
- Comfort Inn Greenville - Haywood Mall
- Midtown Suites-Greenville
- Aloft Greenville Downtown
- Hyatt Place Greenville/Downtown
- Days Inn by Wyndham Anderson
- Homewood Suites by Hilton Greenville Downtown
- Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
- Embassy Suites Greenville Golf Resort & Conference Center
- Hotel Brand
- Hotel Class
- Near An Airport
- Areas Of Upstate South Carolina
- Near An Attraction
- Hotel Theme
- Other Cities Near Upstate South Carolina
- Hotels near Clemson University
- Hotels near Lake Jocassee
- Hotels near Falls Park on the Reedy
- Hotels near Prisma Health Greenville Memorial Hospital
- Hotels near Bon Secours Wellness Arena
- Hotels near Haywood Mall
- Hotels near Greenville Convention Center
- Hotels near The Peace Center
- Hotels near Wofford College
- Hotels near Devils Fork State Park
- Hotels near Anderson University
- Hotels near BMW Performance Center
- Hotels near Bob Jones University
- Hotels near Fluor Field at the West End
- Hotels near Fred W. Symmes Chapel
- Hotels near Memorial Stadium
- Hotels near Heritage Park
- Hotels near Table Rock State Park
- Hotels near WestGate Mall
- Hotels near University of South Carolina Upstate
- Hotels with Free Parking (157)
- Family Hotels (155)
- Hotels with a Pool (126)
- Pet-friendly Hotels (85)
- Historic Hotels (76)
- Hotel Wedding Venues (51)
- Romantic Hotels (42)
- Apartment Hotel (39)
- Luxury Hotels (38)
- Hotels with Hot Tubs (27)
- Resorts & Hotels with Spas (26)
- Hotels with Free Airport Shuttle (21)
- Hotels with smoking rooms (21)
- Hotels with an Indoor Pool (21)
- Beach Hotels (12)
- Boutique Hotels (4)
- Hotels with Early Check-in (4)
- Greenville Hotels
- Lake Lure Hotels
- Highlands Hotels
- Hendersonville Hotels
- Black Mountain Hotels
- Franklin Hotels
- Rock Hill Hotels
- North Carolina Mountains Hotels
- Brevard Hotels
- Anderson Hotels
- Spartanburg Hotels
- Blue Ridge Mountains Hotels
- Cashiers Hotels
- Clemson Hotels
- Seneca Hotels
- Clayton Hotels
- Gastonia Hotels
- Arden Hotels
- Tuckasegee Hotels
- Flat Rock Hotels