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Hotels in Upstate South Carolina

Check Last Minute Upstate South Carolina Hotel Deals

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Choose from 2658 Upstate South Carolina Hotel Deals

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
3.5 out of 5
851 Congaree Rd, Greenville, SC
  • 1 hour drive from Clemson University
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.4/10 Very Good! (1,004 reviews)
"Besides a couple staff being a lil mean, place and location was amazing"

Reviewed on May 18, 2025

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Cambria Hotel Greenville
Cambria Hotel Greenville
3 out of 5
135 Carolina Point Parkway, Greenville, SC
  • 2 hours drive from Clemson University
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,038 reviews)
Clean, well priced.
"Nothing like paying for a clean, good smelling room. In today’s economy, nobody has time to be miserable in a hotel. Highly recommend."

Reviewed on May 18, 2025

Cambria Hotel Greenville
Hilton Greenville
Hilton Greenville
3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
  • 1 hour drive from Clemson University
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8/10 Very Good! (1,008 reviews)
"Beautiful Hotel with nice amenities."

Reviewed on May 20, 2025

Hilton Greenville
Hyatt Regency Greenville
Hyatt Regency Greenville
3.5 out of 5
220 N Main St, Greenville, SC
  • 1 hour drive from Clemson University
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,008 reviews)
"This hotel is so convenient to shops, restaurants, and bars; and it's a 20-minute walk to Reedy Falls Park. Check-in was easy and staff is very helpful. Plus our room was ginormous."

Reviewed on May 17, 2025

Hyatt Regency Greenville
Grand Bohemian Lodge Greenville, Autograph Collection
Grand Bohemian Lodge Greenville, Autograph Collection
4 out of 5
44 EAST CAMPERDOWN WAY, Greenville, SC
  • 1 hour drive from Clemson University
Stay at this 4-star spa hotel in Greenville. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9.4/10 Exceptional! (340 reviews)
"Great place in downtown"

Reviewed on May 7, 2025

Grand Bohemian Lodge Greenville, Autograph Collection
Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & Suites
2.5 out of 5
831 Congaree Rd, Greenville, SC
  • 1 hour drive from Clemson University
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,341 reviews)
Great Overnight Stay
"Great overnight stay. Service was friendly, Room was clean and comfortable. I would definitely stay there again."

Reviewed on May 18, 2025

Best Western Plus Greenville I-385 Inn & Suites
Hyatt Place Greenville/Downtown
Hyatt Place Greenville/Downtown
3 out of 5
128 East Broad Street, Greenville, SC
  • 1 hour drive from Clemson University
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (1,015 reviews)
Great central location.
"Great staff, very clean and the location was perfect! Parked the car in the parking garage and walked all weekend as this was a great central location. Walked to shopping, resturants, bars and also headed to the West end. Will definately stay here again."

Reviewed on May 19, 2025

Hyatt Place Greenville/Downtown
Comfort Inn Greenville - Haywood Mall
Comfort Inn Greenville - Haywood Mall
2.5 out of 5
246 Congaree Road, Greenville, SC
  • 1 hour drive from Clemson University
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,017 reviews)
"Good stay"

Reviewed on May 18, 2025

Comfort Inn Greenville - Haywood Mall
Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference Center
3.5 out of 5
670 Verdae Blvd, Greenville, SC
  • 1 hour drive from Clemson University
Stay at this 3.5-star golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,013 reviews)
"The housekeeper would not make the beds"

Reviewed on May 19, 2025

Embassy Suites Greenville Golf Resort & Conference Center
Hyatt Place Greenville/Haywood
Hyatt Place Greenville/Haywood
3 out of 5
40 W Orchard Park Dr, Greenville, SC
  • 1 hour drive from Clemson University
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, an outdoor pool, and parking (surcharge). Our guests praise the helpful staff and ...
7.6/10 Good! (1,010 reviews)
"Nice for the price and area"

Reviewed on May 20, 2025

Hyatt Place Greenville/Haywood
La Quinta Inn & Suites by Wyndham Greenville Haywood
La Quinta Inn & Suites by Wyndham Greenville Haywood
2.5 out of 5
65 W Orchard Park Dr, Greenville, SC
  • 1 hour drive from Clemson University
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (1,018 reviews)
"Everything was good"

Reviewed on May 16, 2025

La Quinta Inn & Suites by Wyndham Greenville Haywood
Holiday Inn Greenville - Woodruff Road by IHG
Holiday Inn Greenville - Woodruff Road by IHG
3 out of 5
25 OLD COUNTRY ROAD, Greenville, SC
  • 2 hours drive from Clemson University
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.4/10 Very Good! (542 reviews)
Happy Customer!!
"Everything was nice and clean. Very quiet and comfortable room. I will be coming back here to stay."

Reviewed on May 20, 2025

Holiday Inn Greenville - Woodruff Road by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Upstate South Carolina

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Frequently Asked Questions About Upstate South Carolina hotels

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How many hotels are there in Upstate South Carolina?

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