Search for Cheap Deals onLuxury & Trendy Hotels in Upstate South Carolina
Check Last Minute Upstate South Carolina Hotel Deals
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Hotels in Upstate South Carolina
![Hotel Domestique](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/629dbdff_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Hotel Domestique
The price is $461 per night from Feb 24 to Feb 25
$461
includes taxes & fees
Feb 24 - Feb 25
Stay at this 4-star boutique hotel in Travelers Rest. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Mountain Park Golf and Les Mullinax ...
![Inn @ Clemson](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/950a50bf_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Inn @ Clemson
Fully refundableReserve now, pay when you stay
The price is $99 per night from Feb 19 to Feb 20
$99
includes taxes & fees
Feb 19 - Feb 20
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
![The Bleckley Inn](https://images.trvl-media.com/lodging/5000000/4110000/4100300/4100280/4afe4e28_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
The Bleckley Inn
The price is $258 per night from Feb 20 to Feb 21
$258
includes taxes & fees
Feb 20 - Feb 21
Stay at this 3.5-star business-friendly hotel in Anderson. Enjoy free parking, a rooftop terrace, and a fitness center. Popular attractions Church Street Heritage ...
![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/27a45721_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Hyatt Place Greenville/Haywood
Fully refundableReserve now, pay when you stay
The price is $107 per night from Mar 2 to Mar 3
$107
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, an outdoor pool, and parking (surcharge). Our guests praise the helpful staff and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Upstate South Carolina
- Hotels with Free Parking in Upstate South Carolina
- Family Hotels in Upstate South Carolina
- Hotels with a Pool in Upstate South Carolina
- Pet-friendly Hotels in Upstate South Carolina
- Historic Hotels in Upstate South Carolina
- Hotel Wedding Venues in Upstate South Carolina
- Romantic Hotels in Upstate South Carolina
- Apartment Hotel in Upstate South Carolina
- Luxury Hotels in Upstate South Carolina
- Hotels with Hot Tubs in Upstate South Carolina
Top Attractions in Upstate South Carolina
- Hotels near Clemson University
- Hotels near Haywood Mall
- Hotels near BMW Performance Center
- Hotels near Bon Secours Wellness Arena
- Hotels near Falls Park on the Reedy
- Hotels near Prisma Health Greenville Memorial Hospital
- Hotels near The Peace Center
- Hotels near Lake Jocassee
- Hotels near Greenville Convention Center
- Hotels near Fred W. Symmes Chapel
- Hotels near Wofford College
- Hotels near Bob Jones University
- Hotels near Table Rock State Park
- Hotels near Devils Fork State Park
- Hotels near WestGate Mall
- Hotels near Anderson University
- Hotels near Fluor Field at the West End
- Hotels near Memorial Stadium
- Hotels near Spartanburg Memorial Auditorium
- Hotels near University of South Carolina Upstate
Upstate South Carolina Neighborhoods
- Highlands Hotels (55.49 mi)
- Greenville Hotels (8.73 mi)
- Franklin Hotels (68.54 mi)
- Hendersonville Hotels (39.13 mi)
- Clemson Hotels (32.31 mi)
- Rock Hill Hotels (71.73 mi)
- North Carolina Mountains Hotels (64.32 mi)
- Spartanburg Hotels (23.13 mi)
- Black Mountain Hotels (58.45 mi)
- Blue Ridge Mountains Hotels (68.54 mi)
- Seneca Hotels (38.76 mi)
- Brevard Hotels (40.98 mi)
Top Booked Hotels in Upstate South Carolina
Top Boutique Hotel Destinations
- Des Moines Boutique Hotel
- Knoxville Boutique Hotel
- Flagstaff Boutique Hotel
- Rochester Boutique Hotel
- Reno Boutique Hotel
- Raleigh Boutique Hotel
- Anchorage Boutique Hotel
- Fort Myers Boutique Hotel
- Grand Rapids Boutique Hotel
- Zion National Park Boutique Hotel
- Palm Beach Boutique Hotel
- Niagara Falls Boutique Hotel
- Spokane Boutique Hotel
- Springfield Boutique Hotel
- Orlando Boutique Hotel
- Mammoth Lakes Boutique Hotel
- Tallahassee Boutique Hotel
- Oakland Boutique Hotel
- Atlantic City Boutique Hotel
- Shenandoah Valley Boutique Hotel
Car Rentals Near Upstate South Carolina
- Car rentals in Highlands
- Car rentals in Greenville
- Car rentals in Franklin
- Car rentals in Hendersonville
- Car rentals in Clemson
- Car rentals in Rock Hill
- Car rentals in North Carolina Mountains
- Car rentals in Spartanburg
- Car rentals in Black Mountain
- Car rentals in Blue Ridge Mountains
- Car rentals in Seneca
- Car rentals in Brevard
- Car rentals in Anderson
- Car rentals in Lake Lure
- Car rentals in Cashiers
- Car rentals in Ninety Six