Search Cheap Flights toUpstate South Carolina
Search 400 airlines and 321,000 hotels worldwide.
Stop Planning & Start Exploring
FREE 24 hour cancellation on most flights
Upstate South Carolina Flights as Low as $122
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Thu, May 15 - Thu, May 22
RSW
Southwest Florida Intl.
GSP
Greenville-Spartanburg Intl.
$122 Roundtrip, found 1 day ago
$122
Roundtrip
found 1 day ago
Wed, Apr 16 - Sat, Apr 19
ORD
O'Hare Intl.
AVL
Asheville Regional
$199 Roundtrip, found 4 days ago
$199
Roundtrip
found 4 days ago
Wed, Jun 4 - Sat, Jun 7
ORD
O'Hare Intl.
GSP
Greenville-Spartanburg Intl.
$216 Roundtrip, found 5 days ago
$216
Roundtrip
found 5 days ago
Mon, May 5 - Tue, May 6
CLE
Hopkins Intl.
GSP
Greenville-Spartanburg Intl.
$217 Roundtrip, found 10 hours ago
$217
Roundtrip
found 10 hours ago
Mon, May 5 - Tue, May 6
CLE
Hopkins Intl.
GSP
Greenville-Spartanburg Intl.
$217 Roundtrip, found 10 hours ago
$217
Roundtrip
found 10 hours ago
Thu, Jun 19 - Mon, Jun 23
BDL
Bradley Intl.
GSP
Greenville-Spartanburg Intl.
$256 Roundtrip, found 18 hours ago
$256
Roundtrip
found 18 hours ago
Fri, Apr 4 - Tue, Apr 8
MSY
Louis Armstrong New Orleans Intl.
AVL
Asheville Regional
$260 Roundtrip, found 2 days ago
$260
Roundtrip
found 2 days ago
Wed, Mar 26 - Tue, Apr 1
CLE
Hopkins Intl.
AVL
Asheville Regional
$279 Roundtrip, found 11 hours ago
$279
Roundtrip
found 11 hours ago
Tue, Sep 2 - Tue, Sep 16
SAN
San Diego Intl.
GSP
Greenville-Spartanburg Intl.
$287 Roundtrip, found 15 hours ago
$287
Roundtrip
found 15 hours ago
Tue, Jun 24 - Sat, Jun 28
MSY
Louis Armstrong New Orleans Intl.
GSP
Greenville-Spartanburg Intl.
$287 Roundtrip, found 9 hours ago
$287
Roundtrip
found 9 hours ago
Tue, Apr 8 - Tue, Apr 15
BWI
Baltimore Washington Intl. Thurgood Marshall
GSP
Greenville-Spartanburg Intl.
$294 Roundtrip, found 2 days ago
$294
Roundtrip
found 2 days ago
Tue, Apr 29 - Wed, May 7
DAB
Daytona Beach Intl.
AVL
Asheville Regional
$298 Roundtrip, found 1 day ago
$298
Roundtrip
found 1 day ago
Thu, Jun 5 - Sun, Jun 8
MDW
Midway Intl.
GSP
Greenville-Spartanburg Intl.
$322 Roundtrip, found 15 hours ago
$322
Roundtrip
found 15 hours ago
Tue, Apr 1 - Mon, Apr 7
HSV
Huntsville Intl.
GSP
Greenville-Spartanburg Intl.
$477 Roundtrip, found 13 hours ago
$477
Roundtrip
found 13 hours ago
Wed, Mar 26 - Sat, Apr 5
DAB
Daytona Beach Intl.
GSP
Greenville-Spartanburg Intl.
$528 Roundtrip, found 10 hours ago
$528
Roundtrip
found 10 hours ago
Tue, Mar 25 - Tue, Mar 25
RSW
Southwest Florida Intl.
AVL
Asheville Regional
$821 Roundtrip, found 4 days ago
$821
Roundtrip
found 4 days ago
Cheap Flights to Upstate South Carolina
Fall in love at first flight with your vacation to Upstate South Carolina by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Upstate South Carolina on Hotwire, and you’ll be up, up, and on a getaway in no time.
Because once the wheels are down in Upstate South Carolina, the good times start rolling. So buckle up, you’re in for a fun ride.
Frequently Asked Questions About flights to Upstate South Carolina
Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Upstate South Carolina with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.
So all you have to worry about is where you’re headed after the GSP airport.
What is the cheapest month to fly to Upstate South Carolina?
Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Upstate South Carolina are in May, but when you book your flight on Hotwire, savings are always in season.
How many airlines fly to Upstate South Carolina?
Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Upstate South Carolina.
What airport is best to fly into Upstate South Carolina?
When you’re planning your trip to Upstate South Carolina, convenience is the name of the game. Luckily, Upstate South Carolina Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Upstate South Carolina must-do list.
How much are flights to Upstate South Carolina?
Got very cheap flights on your vacation itinerary? When you book your airline tickets to Upstate South Carolina on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $122, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.
How to get cheap flights to Upstate South Carolina?
The trick to saving a stack of cash on your flight to Upstate South Carolina? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $122 right now, why wait?
Destination airport | Greenville-Spartanburg Intl. |
Destination airport IATA code | GSP |
Roundtrip price | $121 |
Last Minute Hotel Deals in Upstate South Carolina
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd, Greenville, SC
The price is $111 per night from Mar 30 to Mar 31
$111
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.4/10 Very Good! (1,008 reviews)
"Would definitely stay here again. Great hospitality"
Reviewed on Mar 23, 2025
Pet-friendly Central Cottage: 2 Miles to Clemson!
Clemson
Stay at this 3-star cottage in Clemson. Enjoy free parking and air conditioning. Popular attractions Clemson Area African American Museum and Fort Hill are located ...
Hyatt Place Greenville/Haywood
40 W Orchard Park Dr, Greenville, SC
The price is $105 per night from Mar 31 to Apr 1
$105
includes taxes & fees
Mar 31 - Apr 1
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, an outdoor pool, and parking (surcharge). Our guests praise the helpful staff and ...
7.6/10 Good! (1,003 reviews)
"My son and I were very comfortable and were cared for, kindly."
Reviewed on Mar 15, 2025
Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY, Greenville, SC
The price is $316 per night from Apr 16 to Apr 17
$316
includes taxes & fees
Apr 16 - Apr 17
Stay at this 4-star spa hotel in Greenville. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9.4/10 Exceptional! (316 reviews)
Perfect Anniversary Get Away
"From the moment my wife and I arrived we experienced friendly exceptional service. The hotel is a showplace and our room had great views of the river /waterfalls. We received awesome attention at check in and a great big shoutout to Tatianna… the best bartender I you will ever meet. Highly recommend ..."
Reviewed on Mar 20, 2025
Cambria Hotel Greenville
135 Carolina Point Parkway, Greenville, SC
The price is $116 per night from Mar 30 to Mar 31
$116
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (979 reviews)
"We booked a room with two beds and when we checked in late they only had a room with one bed. So one person in our party had to sleep on the couch."
Reviewed on Mar 23, 2025
Hyatt Place Greenville/Downtown
128 East Broad Street, Greenville, SC
The price is $135 per night from Mar 30 to Mar 31
$135
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (1,004 reviews)
"Didnt have parking, had to park in garage across street and pay for it. And then charged for breakfast, not included. Room was $209 for 1 night. Not convenient having to hall luggage across street."
Reviewed on Mar 23, 2025
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd, Clemson, SC
The price is $103 per night from Mar 26 to Mar 27
$103
includes taxes & fees
Mar 26 - Mar 27
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,003 reviews)
"Staff was nice and easy check in."
Reviewed on Mar 21, 2025
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd, Greenville, SC
The price is $146 per night from Mar 30 to Mar 31
$146
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3.5-star golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,007 reviews)
"We stay at this property at least once a month and have never been disappointed."
Reviewed on Mar 18, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Hotels With Free Airport Shuttle
Best Western Greenville Airport Inn
5009 Pelham Road, Greenville, SC
The price is $90 per night from Mar 30 to Mar 31
$90
includes taxes & fees
Mar 30 - Mar 31
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,005 reviews)
"Me and my wife enjoyed our stay here"
Reviewed on Mar 17, 2025
Courtyard Greenville-Spartanburg by Marriott
115 The Pkwy, Greer, SC
The price is $147 per night from Apr 3 to Apr 4
$147
includes taxes & fees
Apr 3 - Apr 4
Stay at this 3-star business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (569 reviews)
"."
Reviewed on Mar 22, 2025
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd, Greenville, SC
The price is $111 per night from Mar 30 to Mar 31
$111
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.4/10 Very Good! (1,008 reviews)
"Would definitely stay here again. Great hospitality"
Reviewed on Mar 23, 2025
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd, Greenville, SC
The price is $146 per night from Mar 30 to Mar 31
$146
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3.5-star golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,007 reviews)
"We stay at this property at least once a month and have never been disappointed."
Reviewed on Mar 18, 2025
Fairfield Inn by Marriott Greenville-Spartanburg Airport
48 Fisherman Ln, Greenville, SC
The price is $128 per night from Mar 30 to Mar 31
$128
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff in our ...
8.6/10 Excellent! (538 reviews)
"Inn was clean. Staff very friendly. What you expect from Merriot."
Reviewed on Feb 5, 2025
Greenville Marriott
One Parkway E, Greenville, SC
The price is $134 per night from Apr 18 to Apr 19
$134
includes taxes & fees
Apr 18 - Apr 19
Stay at this 4-star business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (545 reviews)
"Location"
Reviewed on Mar 5, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Nearby Cities
Popular Flight Routes
- Atlanta to New York
- Detroit to Las Vegas
- Dallas to Atlanta
- Dallas to Yosemite National Park
- Toronto to Edmonton
- Chicago to Tulum
- Houston to Lake Tahoe
- Chicago to Las Vegas
- Dallas to Miami
- Dallas to Lake Tahoe
- New York to Miami
- New York to Las Vegas
- Miami to Atlanta
- Minneapolis St Paul to Fort Walton Beach Destin
- Dallas to Branson
- Cleveland to Vero Beach
- Managua to Miami
- Atlanta to Boston
- Austin to Tulum
- Calgary to Vancouver
Flights to Our Favorite Destinations
- Flights to Las Vegas
- Flights to New York
- Flights to Orlando
- Flights to Miami
- Flights to Chicago
- Flights to Panama City Beach
- Flights to San Diego
- Flights to Key West
- Flights to Fort Lauderdale
- Flights to Myrtle Beach
- Flights to Destin
- Flights to Nashville
- Flights to Los Angeles
- Flights to New Orleans
- Flights to Honolulu
- Flights to Gatlinburg
Top Upstate South Carolina Hotels
- Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
- Hyatt Place Greenville/Haywood
- Hyatt Place Greenville/Downtown
- Best Western Plus Clemson Hotel & Conference Center
- Embassy Suites Greenville Golf Resort & Conference Center
- Courtyard by Marriott Greenville Haywood Mall
- Best Western Plus Greenville I-385 Inn & Suites
- La Quinta Inn & Suites by Wyndham Greenville Haywood
- Quality Inn & Suites Greenville - Haywood Mall
- Hilton Greenville