Search Cheap Flights to
Upstate South Carolina

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Upstate South Carolina Flights as Low as $199

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Tue, Oct 21 - Tue, Oct 28
ORD
O'Hare Intl.
GSP
Greenville-Spartanburg Intl.
$199 Roundtrip, found 8 hours ago
$199
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Oct 21 from O'Hare Intl. to Greenville-Spartanburg Intl., returning Tue, Oct 28, priced at $199 found 8 hours ago
Delta
Sat, Oct 18 - Tue, Oct 21
BDL
Bradley Intl.
GSP
Greenville-Spartanburg Intl.
$199 Roundtrip, found 8 hours ago
$199
Roundtrip
found 8 hours ago
Select Delta flight, departing Sat, Oct 18 from Bradley Intl. to Greenville-Spartanburg Intl., returning Tue, Oct 21, priced at $199 found 8 hours ago
United
Tue, Dec 9 - Tue, Dec 16
ORD
O'Hare Intl.
AVL
Asheville Regional
$207 Roundtrip, found 1 day ago
$207
Roundtrip
found 1 day ago
Select United flight, departing Tue, Dec 9 from O'Hare Intl. to Asheville Regional, returning Tue, Dec 16, priced at $207 found 1 day ago
United
Wed, Oct 15 - Mon, Oct 20
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$209 Roundtrip, found 1 day ago
$209
Roundtrip
found 1 day ago
Select United flight, departing Wed, Oct 15 from Newark Liberty Intl. Airport to Greenville-Spartanburg Intl., returning Mon, Oct 20, priced at $209 found 1 day ago
American Airlines
Tue, Oct 21 - Tue, Oct 28
BDL
Bradley Intl.
AVL
Asheville Regional
$216 Roundtrip, found 19 hours ago
$216
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Tue, Oct 21 from Bradley Intl. to Asheville Regional, returning Tue, Oct 28, priced at $216 found 19 hours ago
Delta
Tue, Dec 2 - Tue, Jan 13
EWR
Newark Liberty Intl. Airport
AVL
Asheville Regional
$229 Roundtrip, found 1 day ago
$229
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Dec 2 from Newark Liberty Intl. Airport to Asheville Regional, returning Tue, Jan 13, priced at $229 found 1 day ago
American Airlines
Mon, Sep 29 - Tue, Oct 7
MKE
General Mitchell Intl.
AVL
Asheville Regional
$239 Roundtrip, found 4 days ago
$239
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Sep 29 from General Mitchell Intl. to Asheville Regional, returning Tue, Oct 7, priced at $239 found 4 days ago
American Airlines
Wed, Oct 22 - Wed, Oct 29
FLL
Fort Lauderdale - Hollywood Intl.
AVL
Asheville Regional
$263 Roundtrip, found 4 hours ago
$263
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Wed, Oct 22 from Fort Lauderdale - Hollywood Intl. to Asheville Regional, returning Wed, Oct 29, priced at $263 found 4 hours ago
American Airlines
Wed, Nov 19 - Wed, Nov 26
FLL
Fort Lauderdale - Hollywood Intl.
GSP
Greenville-Spartanburg Intl.
$287 Roundtrip, found 8 hours ago
$287
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Nov 19 from Fort Lauderdale - Hollywood Intl. to Greenville-Spartanburg Intl., returning Wed, Nov 26, priced at $287 found 8 hours ago
American Airlines
Wed, Oct 8 - Sat, Oct 11
LAX
Los Angeles Intl.
AVL
Asheville Regional
$292 Roundtrip, found 6 days ago
$292
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Oct 8 from Los Angeles Intl. to Asheville Regional, returning Sat, Oct 11, priced at $292 found 6 days ago
American Airlines
Tue, Oct 14 - Tue, Oct 21
PHL
Philadelphia Intl.
AVL
Asheville Regional
$313 Roundtrip, found 1 day ago
$313
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Oct 14 from Philadelphia Intl. to Asheville Regional, returning Tue, Oct 21, priced at $313 found 1 day ago
Bargain Flight
Sat, Sep 20 - Tue, Sep 23
LAX
Los Angeles Intl.
GSP
Greenville-Spartanburg Intl.
$321 Roundtrip, found 8 hours ago
$321
Roundtrip
found 8 hours ago
Select Bargain Flight flight, departing Sat, Sep 20 from Los Angeles Intl. to Greenville-Spartanburg Intl., returning Tue, Sep 23, priced at $321 found 8 hours ago
American Airlines
Tue, Oct 14 - Tue, Oct 21
TTN
Mercer
AVL
Asheville Regional
$370 Roundtrip, found 1 day ago
$370
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Oct 14 from Mercer to Asheville Regional, returning Tue, Oct 21, priced at $370 found 1 day ago
American Airlines
Wed, Oct 15 - Sat, Oct 18
TTN
Mercer
GSP
Greenville-Spartanburg Intl.
$376 Roundtrip, found 8 hours ago
$376
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Oct 15 from Mercer to Greenville-Spartanburg Intl., returning Sat, Oct 18, priced at $376 found 8 hours ago
American Airlines
Wed, Oct 15 - Sat, Oct 18
PHL
Philadelphia Intl.
GSP
Greenville-Spartanburg Intl.
$377 Roundtrip, found 8 hours ago
$377
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Oct 15 from Philadelphia Intl. to Greenville-Spartanburg Intl., returning Sat, Oct 18, priced at $377 found 8 hours ago
American Airlines
Sat, Sep 27 - Tue, Sep 30
FSM
Fort Smith Regional
GSP
Greenville-Spartanburg Intl.
$438 Roundtrip, found 8 hours ago
$438
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Sat, Sep 27 from Fort Smith Regional to Greenville-Spartanburg Intl., returning Tue, Sep 30, priced at $438 found 8 hours ago

Cheap Flights to Upstate South Carolina

Fall in love at first flight with your vacation to Upstate South Carolina by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Upstate South Carolina on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Upstate South Carolina, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Upstate South Carolina

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Upstate South Carolina with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Upstate South Carolina?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Upstate South Carolina are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Upstate South Carolina?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Upstate South Carolina.

What airport is best to fly into Upstate South Carolina?

When you’re planning your trip to Upstate South Carolina, convenience is the name of the game. Luckily, Upstate South Carolina Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Upstate South Carolina must-do list.

How much are flights to Upstate South Carolina?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Upstate South Carolina on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $199, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Upstate South Carolina?

The trick to saving a stack of cash on your flight to Upstate South Carolina? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $199 right now, why wait?

Upstate South Carolina Flight Information
Destination airport
Upstate South Carolina
Destination airport IATA code
GSP

Last Minute Hotel Deals in Upstate South Carolina

Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8/10 Very Good! (1,000 reviews)
"Great value! Would stay here again"

Reviewed on Sep 8, 2025

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Hilton Greenville
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson
Stay at this 3-star cottage in Clemson. Enjoy free parking and air conditioning. Popular attractions Clemson Area African American Museum and Larry W. Abernathy ...
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Wooded Cottage - 3 Mi to Clemson University
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

3 out of 5
65 W Orchard Park Dr, Greenville, SC
Stay at this 3-star hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (1,045 reviews)
"I love that it was close to many dinning areas and it has a lobby with small tables that are accessible at any time. I had a meeting in the lobby and no one came and interrupted me talking with my colleague which is priceless to me. They also spoke English and Spanish which is a plus in my book."

Reviewed on Sep 9, 2025

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La Quinta Inn & Suites by Wyndham Greenville Haywood
Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road, Greenville, SC
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,006 reviews)
"overall very satisfied"

Reviewed on Sep 6, 2025

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Best Western Greenville Airport Inn
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd, Greenville, SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,348 reviews)
"Staff was friendly. Breakfast every morning was great. So many options."

Reviewed on Sep 6, 2025

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Best Western Plus Greenville I-385 Inn & Suites
Hyatt Place Greenville Downtown

Hyatt Place Greenville Downtown

3 out of 5
128 East Broad Street, Greenville, SC
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
9.2/10 Wonderful! (1,001 reviews)
"Goog"

Reviewed on Sep 10, 2025

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Hyatt Place Greenville Downtown
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY, Greenville, SC
Stay at this 4-star spa hotel in Greenville. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9.4/10 Exceptional! (381 reviews)
"Pet friendly was great!"

Reviewed on Sep 9, 2025

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Grand Bohemian Lodge Greenville, Autograph Collection
Courtyard by Marriott Greenville Haywood Mall

Courtyard by Marriott Greenville Haywood Mall

3 out of 5
70 Orchard Park Dr, Greenville, SC
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free parking, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (636 reviews)
"Small pet friendly."

Reviewed on Sep 9, 2025

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Courtyard by Marriott Greenville Haywood Mall
See all 2,832 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road, Greenville, SC
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,006 reviews)
"overall very satisfied"

Reviewed on Sep 6, 2025

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Best Western Greenville Airport Inn
Courtyard Greenville-Spartanburg by Marriott

Courtyard Greenville-Spartanburg by Marriott

3 out of 5
115 The Pkwy, Greer, SC
Stay at this 3-star business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (613 reviews)
"."

Reviewed on Sep 1, 2025

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Courtyard Greenville-Spartanburg by Marriott
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.4/10 Very Good! (1,000 reviews)
"I really enjoyed my stay. The staff was very attentive and knowledgeable. The breakfast was fresh each morning and the breakfast attendant, Ms. Beverly was a great hostess. Her service was A1. I will definitely recommend."

Reviewed on Sep 1, 2025

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Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd, Greenville, SC
Stay at this 3.5-star golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,000 reviews)
"Loved this hotel! Beautiful property, nice rooms, good breakfast and kick back."

Reviewed on Sep 8, 2025

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Embassy Suites Greenville Golf Resort & Conference Center
Fairfield Inn by Marriott Greenville-Spartanburg Airport

Fairfield Inn by Marriott Greenville-Spartanburg Airport

2.5 out of 5
48 Fisherman Ln, Greenville, SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff in our ...
8.6/10 Excellent! (573 reviews)
GREAT VALUE!
"GREAT ROOMS! GREAT SERVICE! Our Night Front Desk Clerk Was So Super Helpful Solving An Issue With Our TV! Shout Out To BRI!"

Reviewed on Sep 9, 2025

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Fairfield Inn by Marriott Greenville-Spartanburg Airport
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E, Greenville, SC
Stay at this 4-star business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (591 reviews)
"we enjoyed the bar"

Reviewed on Aug 29, 2025

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Greenville Marriott
See all 2,832 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.