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Upstate South Carolina

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Upstate South Carolina Flights as Low as $103

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Breeze Airways
Mon, Mar 30 - Fri, Apr 3
BDL
Bradley Intl.
GSP
Greenville-Spartanburg Intl.
$103 Roundtrip, found 4 hours ago
$103
Roundtrip
found 4 hours ago
Select Breeze Airways flight, departing Mon, Mar 30 from Bradley Intl. to Greenville-Spartanburg Intl., returning Fri, Apr 3, priced at $103 found 4 hours ago
American Airlines
Sat, Feb 28 - Wed, Mar 4
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$152 Roundtrip, found 4 hours ago
$152
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sat, Feb 28 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Wed, Mar 4, priced at $152 found 4 hours ago
Delta
Tue, Apr 7 - Tue, Apr 14
ALB
Albany Intl.
AVL
Asheville Regional
$198 Roundtrip, found 2 days ago
$198
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Apr 7 from Albany Intl. to Asheville Regional, returning Tue, Apr 14, priced at $198 found 2 days ago
American Airlines
Fri, Feb 27 - Tue, Mar 10
ORD
O'Hare Intl.
AVL
Asheville Regional
$209 Roundtrip, found 4 hours ago
$209
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Fri, Feb 27 from O'Hare Intl. to Asheville Regional, returning Tue, Mar 10, priced at $209 found 4 hours ago
American Airlines
Fri, Feb 20 - Mon, Feb 23
ORD
O'Hare Intl.
GSP
Greenville-Spartanburg Intl.
$216 Roundtrip, found 4 hours ago
$216
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Fri, Feb 20 from O'Hare Intl. to Greenville-Spartanburg Intl., returning Mon, Feb 23, priced at $216 found 4 hours ago
Bargain Flight
Tue, Mar 10 - Tue, Mar 17
BOS
Logan Intl.
GSP
Greenville-Spartanburg Intl.
$236 Roundtrip, found 4 hours ago
$236
Roundtrip
found 4 hours ago
Select Bargain Flight flight, departing Tue, Mar 10 from Logan Intl. to Greenville-Spartanburg Intl., returning Tue, Mar 17, priced at $236 found 4 hours ago
Delta
Tue, Mar 24 - Tue, Mar 31
MKE
General Mitchell Intl.
AVL
Asheville Regional
$236 Roundtrip, found 20 hours ago
$236
Roundtrip
found 20 hours ago
Select Delta flight, departing Tue, Mar 24 from General Mitchell Intl. to Asheville Regional, returning Tue, Mar 31, priced at $236 found 20 hours ago
Delta
Sat, Feb 21 - Wed, Feb 25
BUF
Buffalo Niagara Intl.
AVL
Asheville Regional
$259 Roundtrip, found 1 day ago
$259
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Feb 21 from Buffalo Niagara Intl. to Asheville Regional, returning Wed, Feb 25, priced at $259 found 1 day ago
American Airlines
Tue, Apr 28 - Tue, May 5
MHT
Manchester-Boston Regional
GSP
Greenville-Spartanburg Intl.
$271 Roundtrip, found 4 hours ago
$271
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Apr 28 from Manchester-Boston Regional to Greenville-Spartanburg Intl., returning Tue, May 5, priced at $271 found 4 hours ago
Delta
Tue, Mar 24 - Sat, Mar 28
ATW
Appleton Intl.
AVL
Asheville Regional
$286 Roundtrip, found 20 hours ago
$286
Roundtrip
found 20 hours ago
Select Delta flight, departing Tue, Mar 24 from Appleton Intl. to Asheville Regional, returning Sat, Mar 28, priced at $286 found 20 hours ago
Delta
Thu, Feb 19 - Tue, Feb 24
BUF
Buffalo Niagara Intl.
GSP
Greenville-Spartanburg Intl.
$297 Roundtrip, found 4 hours ago
$297
Roundtrip
found 4 hours ago
Select Delta flight, departing Thu, Feb 19 from Buffalo Niagara Intl. to Greenville-Spartanburg Intl., returning Tue, Feb 24, priced at $297 found 4 hours ago
American Airlines
Tue, Apr 28 - Tue, May 12
ALB
Albany Intl.
GSP
Greenville-Spartanburg Intl.
$297 Roundtrip, found 4 hours ago
$297
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Apr 28 from Albany Intl. to Greenville-Spartanburg Intl., returning Tue, May 12, priced at $297 found 4 hours ago
Delta
Tue, Mar 31 - Tue, Apr 7
MKE
General Mitchell Intl.
GSP
Greenville-Spartanburg Intl.
$297 Roundtrip, found 20 hours ago
$297
Roundtrip
found 20 hours ago
Select Delta flight, departing Tue, Mar 31 from General Mitchell Intl. to Greenville-Spartanburg Intl., returning Tue, Apr 7, priced at $297 found 20 hours ago
American Airlines
Sat, Apr 4 - Wed, Apr 8
DCA
Ronald Reagan Washington National
AVL
Asheville Regional
$313 Roundtrip, found 3 days ago
$313
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Apr 4 from Ronald Reagan Washington National to Asheville Regional, returning Wed, Apr 8, priced at $313 found 3 days ago
Delta
Sun, Feb 1 - Sat, Feb 21
ATW
Appleton Intl.
GSP
Greenville-Spartanburg Intl.
$315 Roundtrip, found 4 hours ago
$315
Roundtrip
found 4 hours ago
Select Delta flight, departing Sun, Feb 1 from Appleton Intl. to Greenville-Spartanburg Intl., returning Sat, Feb 21, priced at $315 found 4 hours ago
United
Wed, Jul 29 - Wed, Aug 26
CPR
Natrona County Intl.
GSP
Greenville-Spartanburg Intl.
$694 Roundtrip, found 6 hours ago
$694
Roundtrip
found 6 hours ago
Select United flight, departing Wed, Jul 29 from Natrona County Intl. to Greenville-Spartanburg Intl., returning Wed, Aug 26, priced at $694 found 6 hours ago

Cheap Flights to Upstate South Carolina

Fall in love at first flight with your vacation to Upstate South Carolina by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Upstate South Carolina on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Upstate South Carolina, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Upstate South Carolina

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Upstate South Carolina with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Upstate South Carolina?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Upstate South Carolina are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Upstate South Carolina?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Upstate South Carolina.

What airport is best to fly into Upstate South Carolina?

When you’re planning your trip to Upstate South Carolina, convenience is the name of the game. Luckily, Upstate South Carolina Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Upstate South Carolina must-do list.

How much are flights to Upstate South Carolina?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Upstate South Carolina on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $103, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Upstate South Carolina?

The trick to saving a stack of cash on your flight to Upstate South Carolina? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $103 right now, why wait?

Upstate South Carolina Flight Information
Destination airport
Asheville Regional
Destination airport IATA code
AVL
Roundtrip price
$152

Last Minute Hotel Deals in Upstate South Carolina

Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,001 reviews)
Place is very

Reviewed on Jan 21, 2026

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Hilton Greenville
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

3 out of 5
40 W Orchard Park Dr Greenville SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,007 reviews)
Friendly staff and comfortable room

Reviewed on Jan 21, 2026

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Hyatt Place Greenville/Haywood
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd Greenville SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.4/10 Very Good! (1,001 reviews)
The room was so clean and everything was quiet. I will be back

Reviewed on Jan 29, 2026

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Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Book a stay at this spa hotel in Greenville. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9.4/10 Exceptional! (439 reviews)
Awesome place and service

Reviewed on Jan 23, 2026

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Grand Bohemian Lodge Greenville, Autograph Collection
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
Book a stay at this golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,041 reviews)
Room was spotless, staff was great, love the shower gel and shampoo! Always a good time at this facility - you never need to go out the hotel provides it all!

Reviewed on Jan 25, 2026

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Embassy Suites Greenville Golf Resort & Conference Center
Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest

2.5 out of 5
501 South Blackstock Rd Spartanburg SC
Book a stay at this business-friendly hotel in Spartanburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions WestGate Mall and Regal Spartan ...
5.8/10 (535 reviews)
Girl at check-in was more focused on a personal phone call than checking us in. Was rude when informed that light switch did not turn on any lights in the room. Yelled up from lobby that you have to walk into the DARK room and turn light on next to the bed. Light by TV did not work, did not offer ...

Reviewed on Jan 6, 2026

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Sleep Inn Spartanburg Southwest
Embassy Suites by Hilton Greenville Downtown Riverplace

Embassy Suites by Hilton Greenville Downtown Riverplace

3.5 out of 5
250 Riverplace Greenville SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the bar and the helpful staff ...
9/10 Wonderful! (1,007 reviews)
The room was neat and clean. The cleaning and kitchen staff were very kind and courteous. It was a great stay.

Reviewed on Jan 24, 2026

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Embassy Suites by Hilton Greenville Downtown Riverplace
Hampton Inn & Suites Greenville-Downtown-RiverPlace

Hampton Inn & Suites Greenville-Downtown-RiverPlace

2.5 out of 5
171 Riverplace Greenville SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,009 reviews)
Breakfast fare needs improvement for a higher end Hampton Inn

Reviewed on Jan 25, 2026

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Hampton Inn & Suites Greenville-Downtown-RiverPlace
See all 2,934 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road Greenville SC
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,005 reviews)
It was clean nice peaceful and quiet no disturbance rest well great

Reviewed on Dec 24, 2025

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Best Western Greenville Airport Inn
Courtyard Greenville-Spartanburg by Marriott

Courtyard Greenville-Spartanburg by Marriott

3 out of 5
115 The Pkwy Greer SC
Book a stay at this business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (638 reviews)
excellent facility

Reviewed on Jan 7, 2026

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Courtyard Greenville-Spartanburg by Marriott
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd Greenville SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.4/10 Very Good! (1,001 reviews)
The room was so clean and everything was quiet. I will be back

Reviewed on Jan 29, 2026

Get rates
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
Book a stay at this golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,041 reviews)
Room was spotless, staff was great, love the shower gel and shampoo! Always a good time at this facility - you never need to go out the hotel provides it all!

Reviewed on Jan 25, 2026

Get rates
Embassy Suites Greenville Golf Resort & Conference Center
Fairfield Inn by Marriott Greenville-Spartanburg Airport

Fairfield Inn by Marriott Greenville-Spartanburg Airport

2.5 out of 5
48 Fisherman Ln Greenville SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff in our ...
8.6/10 Excellent! (604 reviews)
Staff was fantastic, so accommodating and friendly, made sure we had everything we needed. Room clean. Shuttle to airport right on time at 4:10am, quick & again so friendly. Parking free for our time away of 10 days. Would definitely stay again.

Reviewed on Jan 24, 2026

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Fairfield Inn by Marriott Greenville-Spartanburg Airport
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E Greenville SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (616 reviews)
Stay here often. Always great service.

Reviewed on Jan 18, 2026

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Greenville Marriott
See all 2,934 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.