Search Cheap Flights to
Upstate South Carolina

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Upstate South Carolina Flights as Low as $149

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

JetBlue Airways
Sat, Aug 16 - Sat, Aug 23
BOS
Logan Intl.
AVL
Asheville Regional
$149 Roundtrip, found 12 hours ago
$149
Roundtrip
found 12 hours ago
Select JetBlue Airways flight, departing Sat, Aug 16 from Logan Intl. to Asheville Regional, returning Sat, Aug 23, priced at $149 found 12 hours ago
American Airlines
Tue, Sep 30 - Tue, Oct 7
MIA
Miami Intl.
AVL
Asheville Regional
$159 Roundtrip, found 15 hours ago
$159
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Tue, Sep 30 from Miami Intl. to Asheville Regional, returning Tue, Oct 7, priced at $159 found 15 hours ago
Bargain Flight
Tue, Oct 21 - Fri, Oct 31
STL
Lambert-St. Louis Intl.
AVL
Asheville Regional
$209 Roundtrip, found 1 day ago
$209
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Oct 21 from Lambert-St. Louis Intl. to Asheville Regional, returning Fri, Oct 31, priced at $209 found 1 day ago
Bargain Flight
Tue, Aug 19 - Wed, Aug 27
BOS
Logan Intl.
GSP
Greenville-Spartanburg Intl.
$212 Roundtrip, found 2 days ago
$212
Roundtrip
found 2 days ago
Select Bargain Flight flight, departing Tue, Aug 19 from Logan Intl. to Greenville-Spartanburg Intl., returning Wed, Aug 27, priced at $212 found 2 days ago
Bargain Flight
Wed, Sep 3 - Tue, Sep 9
DTW
Detroit Metropolitan Wayne County
GSP
Greenville-Spartanburg Intl.
$225 Roundtrip, found 3 days ago
$225
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Wed, Sep 3 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Tue, Sep 9, priced at $225 found 3 days ago
American Airlines
Sun, Aug 31 - Sat, Sep 6
DTW
Detroit Metropolitan Wayne County
AVL
Asheville Regional
$229 Roundtrip, found 1 day ago
$229
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Aug 31 from Detroit Metropolitan Wayne County to Asheville Regional, returning Sat, Sep 6, priced at $229 found 1 day ago
Delta
Tue, Oct 21 - Tue, Oct 28
STL
Lambert-St. Louis Intl.
GSP
Greenville-Spartanburg Intl.
$237 Roundtrip, found 3 days ago
$237
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Oct 21 from Lambert-St. Louis Intl. to Greenville-Spartanburg Intl., returning Tue, Oct 28, priced at $237 found 3 days ago
American Airlines
Sat, Oct 4 - Wed, Oct 8
SMF
Sacramento Intl.
AVL
Asheville Regional
$251 Roundtrip, found 19 hours ago
$251
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Sat, Oct 4 from Sacramento Intl. to Asheville Regional, returning Wed, Oct 8, priced at $251 found 19 hours ago
American Airlines
Wed, Oct 22 - Sat, Oct 25
JAX
Jacksonville Intl.
AVL
Asheville Regional
$251 Roundtrip, found 1 day ago
$251
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Oct 22 from Jacksonville Intl. to Asheville Regional, returning Sat, Oct 25, priced at $251 found 1 day ago
American Airlines
Thu, Aug 14 - Sun, Aug 17
DEN
Denver Intl.
GSP
Greenville-Spartanburg Intl.
$273 Roundtrip, found 3 days ago
$273
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Aug 14 from Denver Intl. to Greenville-Spartanburg Intl., returning Sun, Aug 17, priced at $273 found 3 days ago
Delta
Sat, Aug 16 - Mon, Aug 18
DEN
Denver Intl.
AVL
Asheville Regional
$273 Roundtrip, found 1 day ago
$273
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Aug 16 from Denver Intl. to Asheville Regional, returning Mon, Aug 18, priced at $273 found 1 day ago
Delta
Tue, Oct 21 - Wed, Oct 22
MSY
Louis Armstrong New Orleans Intl.
AVL
Asheville Regional
$277 Roundtrip, found 2 days ago
$277
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Oct 21 from Louis Armstrong New Orleans Intl. to Asheville Regional, returning Wed, Oct 22, priced at $277 found 2 days ago
Delta
Tue, Aug 5 - Mon, Aug 11
ROC
Greater Rochester Intl.
AVL
Asheville Regional
$290 Roundtrip, found 1 day ago
$290
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Aug 5 from Greater Rochester Intl. to Asheville Regional, returning Mon, Aug 11, priced at $290 found 1 day ago
Delta
Sat, Aug 16 - Tue, Aug 19
ROC
Greater Rochester Intl.
GSP
Greenville-Spartanburg Intl.
$308 Roundtrip, found 21 hours ago
$308
Roundtrip
found 21 hours ago
Select Delta flight, departing Sat, Aug 16 from Greater Rochester Intl. to Greenville-Spartanburg Intl., returning Tue, Aug 19, priced at $308 found 21 hours ago
Delta
Thu, Sep 4 - Sun, Sep 7
BNA
Nashville Intl.
AVL
Asheville Regional
$312 Roundtrip, found 15 hours ago
$312
Roundtrip
found 15 hours ago
Select Delta flight, departing Thu, Sep 4 from Nashville Intl. to Asheville Regional, returning Sun, Sep 7, priced at $312 found 15 hours ago
Delta
Mon, Aug 18 - Tue, Aug 19
SMF
Sacramento Intl.
GSP
Greenville-Spartanburg Intl.
$318 Roundtrip, found 1 day ago
$318
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Aug 18 from Sacramento Intl. to Greenville-Spartanburg Intl., returning Tue, Aug 19, priced at $318 found 1 day ago

Cheap Flights to Upstate South Carolina

Fall in love at first flight with your vacation to Upstate South Carolina by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Upstate South Carolina on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Upstate South Carolina, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Upstate South Carolina

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Upstate South Carolina with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Upstate South Carolina?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Upstate South Carolina are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Upstate South Carolina?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Upstate South Carolina.

What airport is best to fly into Upstate South Carolina?

When you’re planning your trip to Upstate South Carolina, convenience is the name of the game. Luckily, Upstate South Carolina Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Upstate South Carolina must-do list.

How much are flights to Upstate South Carolina?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Upstate South Carolina on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $149, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Upstate South Carolina?

The trick to saving a stack of cash on your flight to Upstate South Carolina? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $149 right now, why wait?

Upstate South Carolina Flight Information
Destination airport
Asheville Regional
Destination airport IATA code
AVL
Roundtrip price
$149

Last Minute Hotel Deals in Upstate South Carolina

Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8/10 Very Good! (1,005 reviews)
Great place to stay
"We enjoyed our day at the Greenville Hilton. All the staff we encountered was really nice and helpful. The location is so convenient and the price is really reasonable."

Reviewed on Jul 21, 2025

Get rates
Hilton Greenville
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.4/10 Very Good! (1,006 reviews)
"Finally a hotel with hot water!"

Reviewed on Jul 20, 2025

Get rates
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

3 out of 5
65 W Orchard Park Dr, Greenville, SC
Stay at this 3-star hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (1,017 reviews)
"I book a room that wasn’t available so I had to down size and only received 50$ back as a refund which I’m waiting 5 days to receive it and the deposit."

Reviewed on Jul 23, 2025

Get rates
La Quinta Inn & Suites by Wyndham Greenville Haywood
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St, Greenville, SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,022 reviews)
"It was just OK. Next time we go back to Greenville, we plan to stay somewhere else."

Reviewed on Jul 23, 2025

Get rates
Hyatt Regency Greenville
Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport

2.5 out of 5
205 Entertainment Blvd, Greenville, SC
Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Haywood Mall and BMW Performance Center are located nearby.
8.4/10 Very Good! (122 reviews)
"Smooth check in. Clean room. Fair price. What else matters?"

Reviewed on Jul 23, 2025

Get rates
Woodspring Suites Greenville Airport
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd, Anderson, SC
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,013 reviews)
"My recent stay at the Days Inn Anderson, SC was fantastic! The staff was incredibly friendly and helpful from check-in to check-out. My room was clean, comfortable, and had everything I needed for a relaxing night. I especially appreciated the comfortable bed and the quiet atmosphere, which allowed ..."

Reviewed on Jul 25, 2025

Get rates
Days Inn by Wyndham Anderson
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road, Greenville, SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,015 reviews)
"Great place close to convention center and shopping and restaurants"

Reviewed on Jul 24, 2025

Get rates
Comfort Inn Greenville - Haywood Mall
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd, Greenville, SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,347 reviews)
"The staff was welcoming and very helpful. The room was nice. The breakfast was great!"

Reviewed on Jul 21, 2025

Get rates
Best Western Plus Greenville I-385 Inn & Suites
See all 2,758 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road, Greenville, SC
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,004 reviews)
"Clean and friendly staff"

Reviewed on Jul 12, 2025

Get rates
Best Western Greenville Airport Inn
Courtyard Greenville-Spartanburg by Marriott

Courtyard Greenville-Spartanburg by Marriott

3 out of 5
115 The Pkwy, Greer, SC
Stay at this 3-star business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (603 reviews)
"I liked the bistro. The menu was simple but enjoyable."

Reviewed on Jul 22, 2025

Get rates
Courtyard Greenville-Spartanburg by Marriott
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.4/10 Very Good! (1,006 reviews)
"Finally a hotel with hot water!"

Reviewed on Jul 20, 2025

Get rates
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd, Greenville, SC
Stay at this 3.5-star golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,014 reviews)
"Everything you need is right there. BreakfStwas good."

Reviewed on Jul 24, 2025

Get rates
Embassy Suites Greenville Golf Resort & Conference Center
Fairfield Inn by Marriott Greenville-Spartanburg Airport

Fairfield Inn by Marriott Greenville-Spartanburg Airport

2.5 out of 5
48 Fisherman Ln, Greenville, SC
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff in our ...
8.6/10 Excellent! (562 reviews)
"Area had lots to dine"

Reviewed on Jul 18, 2025

Get rates
Fairfield Inn by Marriott Greenville-Spartanburg Airport
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E, Greenville, SC
Stay at this 4-star business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (582 reviews)
"The staff was excellent and the facility was user friendly"

Reviewed on Jul 14, 2025

Get rates
Greenville Marriott
See all 2,758 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.