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Hotels in Seneca

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Check Last Minute Seneca Hotel Deals

Tonight Feb 28 - Mar 1This weekend Feb 28 - Mar 2

Choose from 1521 Seneca Hotel Deals

Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
  • 11 min drive from Keowee Reservoir
The price is $134 per night from Mar 2 to Mar 3
$134
includes taxes & fees
Mar 2 - Mar 3
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.8/10 Excellent! (795 reviews)
"Convenient location, spacious and clean room, decent food and drink options on site"

Reviewed on Feb 21, 2025

Lakeside Lodge Clemson
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 out of 5
1011 East North 1st Street, Seneca, SC
  • 7 min drive from Keowee Reservoir
The price is $139 per night from Mar 23 to Mar 24
$139
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (579 reviews)
"Great hotel breakfast."

Reviewed on Feb 25, 2025

Hampton Inn & Suites Seneca-Clemson Area
Postcard Cabins Lake Hartwell
Postcard Cabins Lake Hartwell
2 out of 5
299 Outpost Rd, Seneca, SC
  • 20 min drive from Keowee Reservoir
The price is $110 per night from Mar 2 to Mar 3
$110
includes taxes & fees
Mar 2 - Mar 3
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
10/10 Exceptional! (3 reviews)
"This is a fantastic place to stay and get away. Good for quiet work or true relaxation. Internet was blazing fast too. Can I stay forever?"

Reviewed on Feb 16, 2025

Postcard Cabins Lake Hartwell
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 out of 5
13050 Clemson Blvd, Seneca, SC
  • 11 min drive from Keowee Reservoir
The price is $130 per night from Mar 23 to Mar 24
$130
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (675 reviews)
"Perfect for short trip!"

Reviewed on Feb 26, 2025

Tru by Hilton Seneca Clemson
Best Western Seneca-Clemson
Best Western Seneca-Clemson
2.5 out of 5
511 Bypass Highway 123, Seneca, SC
  • 8 min drive from Keowee Reservoir
The price is $102 per night from Mar 6 to Mar 7
$102
includes taxes & fees
Mar 6 - Mar 7
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (573 reviews)
"clean, staff friendly and accommodating, convenient"

Reviewed on Feb 24, 2025

Best Western Seneca-Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 out of 5
800 BYPASS 123, Seneca, SC
  • 10 min drive from Keowee Reservoir
The price is $142 per night from Mar 2 to Mar 3
$142
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (133 reviews)
"Very nice hotel !"

Reviewed on Jan 18, 2025

Fairfield Inn & Suites Seneca Clemson Univ Area
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 out of 5
1310 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $103 per night from Mar 2 to Mar 3
$103
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,003 reviews)
"staff was kind, place really clean, the only thing I dint liked was the breakfast, just a few options, food was cold."

Reviewed on Feb 22, 2025

Best Western Plus Clemson Hotel & Conference Center
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
4 out of 5
110 Sloan St, Clemson, SC
  • 15 min drive from Keowee Reservoir
The price is $199 per night from Mar 16 to Mar 17
$199
includes taxes & fees
Mar 16 - Mar 17
Stay at this 4-star hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and valet parking (surcharge). Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (501 reviews)
"There is nothing not to love about The Shepherd. It is such a wonderful hotel. Everything is top notch , from the decorations to the people. We love it!"

Reviewed on Feb 27, 2025

The Shepherd Hotel Downtown Clemson
Inn @ Clemson
Inn @ Clemson
2.5 out of 5
1303 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $99 per night from Mar 2 to Mar 3
$99
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,004 reviews)
Deserving of it's high rating.
"Nice, decently priced hotel conveniently located with a great staff. Check in was a breeze and Caroline at the front desk was very helpful. The only thing that was amiss was the fridge in my room needed to be replaced because it was not staying cool and the TV still had factory suggestion pop ups ..."

Reviewed on Feb 25, 2025

Inn @ Clemson
Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University Area
2.5 out of 5
1305 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $103 per night from Mar 6 to Mar 7
$103
includes taxes & fees
Mar 6 - Mar 7
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,000 reviews)
"Stayed here as it was close to Clemson since we were attending a graduation ceremony. The hotel was close and the room was good for the night we stayed."

Reviewed on Feb 17, 2025

Comfort Inn & Suites Clemson - University Area
Pet-friendly Central Cottage: 2 Miles to Clemson!
Pet-friendly Central Cottage: 2 Miles to Clemson!
3 out of 5
Clemson
  • 16 min drive from Keowee Reservoir
Stay at this 3-star cottage in Clemson. Enjoy free parking and air conditioning. Popular attractions Clemson Area African American Museum and Larry W. Abernathy ...
Pet-friendly Central Cottage: 2 Miles to Clemson!
Clemson University's James F. Martin Inn
Clemson University's James F. Martin Inn
3 out of 5
240 Madren Center Drive, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $176 per night from Mar 2 to Mar 3
$176
includes taxes & fees
Mar 2 - Mar 3
Stay at this 3-star golf hotel in Clemson. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our ...
9.4/10 Exceptional! (856 reviews)
Visit to Tiger town!
"Went to visit Clemson University with my son. Great location, great hotel!"

Reviewed on Feb 26, 2025

Clemson University's James F. Martin Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Seneca

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $99. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Seneca hotel deals at the last minute.

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Frequently Asked Questions About Seneca hotels

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How many hotels are there in Seneca?

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Finding a cheap car rental deal in Seneca is as easy as scoring cheap hotels in Seneca. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.