Search for Cheap Deals on
Hotels in Salem

Choose from 3138 Salem Hotel Deals

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 out of 5
1310 Tiger Blvd, Clemson, SC
  • 24 min drive from Lake Keowee
The price is $103 per night from Mar 30 to Mar 31
$103
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,000 reviews)
"Staff was nice and easy check in."

Reviewed on Mar 21, 2025

Best Western Plus Clemson Hotel & Conference Center
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
4 out of 5
110 Sloan St, Clemson, SC
  • 24 min drive from Lake Keowee
The price is $199 per night from Apr 23 to Apr 24
$199
includes taxes & fees
Apr 23 - Apr 24
Stay at this 4-star hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and valet parking (surcharge). Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (517 reviews)
"Amazing location and phenomenal staff."

Reviewed on Mar 21, 2025

The Shepherd Hotel Downtown Clemson
Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
  • 21 min drive from Lake Keowee
The price is $134 per night from Mar 26 to Mar 27
$134
includes taxes & fees
Mar 26 - Mar 27
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.8/10 Excellent! (816 reviews)
"Beautiful setting, friendly staff, clean and relaxing atmosphere."

Reviewed on Mar 20, 2025

Lakeside Lodge Clemson
Inn @ Clemson
Inn @ Clemson
2.5 out of 5
1303 Tiger Blvd, Clemson, SC
  • 24 min drive from Lake Keowee
The price is $110 per night from Mar 26 to Mar 27
$110
includes taxes & fees
Mar 26 - Mar 27
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,002 reviews)
"N/A"

Reviewed on Mar 18, 2025

Inn @ Clemson
Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University Area
2.5 out of 5
1305 Tiger Blvd, Clemson, SC
  • 24 min drive from Lake Keowee
The price is $103 per night from Apr 1 to Apr 2
$103
includes taxes & fees
Apr 1 - Apr 2
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,002 reviews)
"The facility was delightful. It's been recently renovated and very well done. The staff was delightful, especially the cleaning service. I would definitely stay there again."

Reviewed on Mar 21, 2025

Comfort Inn & Suites Clemson - University Area
Pet-friendly Central Cottage: 2 Miles to Clemson!
Pet-friendly Central Cottage: 2 Miles to Clemson!
3 out of 5
Clemson
  • 22 min drive from Lake Keowee
Stay at this 3-star cottage in Clemson. Enjoy free parking and air conditioning. Popular attractions Clemson Area African American Museum and Fort Hill are located ...
Pet-friendly Central Cottage: 2 Miles to Clemson!
Holiday Inn Express & Suites Clemson by IHG
Holiday Inn Express & Suites Clemson by IHG
2.5 out of 5
1381 Tiger Blvd, Clemson, SC
  • 25 min drive from Lake Keowee
The price is $125 per night from Apr 1 to Apr 2
$125
includes taxes & fees
Apr 1 - Apr 2
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (866 reviews)
"J"

Reviewed on Mar 7, 2025

Holiday Inn Express & Suites Clemson by IHG
Holiday Inn Express Brevard City Center by IHG
Holiday Inn Express Brevard City Center by IHG
2.5 out of 5
185 Old Hendersonville Hwy, Brevard, NC
  • 1 hour drive from Lake Keowee
The price is $149 per night from Mar 31 to Apr 1
$149
includes taxes & fees
Mar 31 - Apr 1
Book a stay at this business-friendly hotel in Brevard. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (493 reviews)
"Na"

Reviewed on Mar 7, 2025

Holiday Inn Express Brevard City Center by IHG
Days Inn by Wyndham Easley/Greenville/Clemson Area
Days Inn by Wyndham Easley/Greenville/Clemson Area
2 out of 5
121 Days Inn Dr, Easley, SC
  • 53 min drive from Lake Keowee
The price is $75 per night from Mar 27 to Mar 28
$75
includes taxes & fees
Mar 27 - Mar 28
Book a stay at this business-friendly motel in Easley. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6/10 (719 reviews)
"Everything was fine"

Reviewed on Mar 23, 2025

Days Inn by Wyndham Easley/Greenville/Clemson Area
Quality Inn Seneca US-123
Quality Inn Seneca US-123
2.5 out of 5
226 Hi Tech Rd, Seneca, SC
  • 23 min drive from Lake Keowee
The price is $102 per night from Apr 15 to Apr 16
$102
includes taxes & fees
Apr 15 - Apr 16
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (575 reviews)
"Clean and efficient somewhat dated"

Reviewed on Mar 6, 2025

Quality Inn Seneca US-123
The Abernathy of Clemson
The Abernathy of Clemson
4 out of 5
157 Old Greenville Hwy, Clemson, SC
  • 24 min drive from Lake Keowee
The price is $199 per night from Mar 31 to Apr 1
$199
includes taxes & fees
Mar 31 - Apr 1
Stay at this 4-star business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.6/10 Exceptional! (497 reviews)
"It was a great stay!"

Reviewed on Mar 19, 2025

The Abernathy of Clemson
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 out of 5
1011 East North 1st Street, Seneca, SC
  • 20 min drive from Lake Keowee
The price is $133 per night from Mar 30 to Mar 31
$133
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (585 reviews)
"Very clean and the staff is very helpful"

Reviewed on Mar 12, 2025

Hampton Inn & Suites Seneca-Clemson Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Salem

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Salem hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Salem.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Salem’s 3,138 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $75. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Salem hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Salem. No matter your reason for visiting Salem, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Salem hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Salem for as low as $75.

How many hotels are there in Salem?

With over 3,138 hotels in Salem, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $75.

How to find cheap car rentals in Salem?

Finding a cheap car rental deal in Salem is as easy as scoring cheap hotels in Salem. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.