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Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd, Clemson, SC
  • 24 min drive from Lake Keowee
Book a stay at this business-friendly hotel in Clemson. Enjoy free parking, an outdoor pool, and a 24-hour fitness center. Our guests praise the helpful staff ...
Best Western Plus Clemson Hotel & Conference Center
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd, Clemson, SC
  • 24 min drive from Lake Keowee
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
Comfort Inn & Suites Clemson - University Area
Trailborn Highlands

Trailborn Highlands

4 out of 5
96 Log Cabin Lane, Highlands, NC
  • 1 hour drive from Lake Keowee
Stay at this 4-star hotel in Highlands. Enjoy free parking, onsite spa services, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. ...
Trailborn Highlands
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St, Clemson, SC
  • 24 min drive from Lake Keowee
Stay at this 4-star hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our ...
The Shepherd Hotel Downtown Clemson
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd, Clemson, SC
  • 24 min drive from Lake Keowee
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Inn @ Clemson
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson
  • 22 min drive from Lake Keowee
Stay at this 3-star cottage in Clemson. Enjoy free parking and air conditioning. Popular attractions Clemson Area African American Museum and Larry W. Abernathy ...
Wooded Cottage - 3 Mi to Clemson University
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd, Seneca, SC
  • 21 min drive from Lake Keowee
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Lakeside Lodge Clemson
Holiday Inn Express Brevard City Center by IHG

Holiday Inn Express Brevard City Center by IHG

2.5 out of 5
185 Old Hendersonville Hwy, Brevard, NC
  • 1 hour drive from Lake Keowee
Book a stay at this business-friendly hotel in Brevard. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Express Brevard City Center by IHG
Comfort Inn & Suites

Comfort Inn & Suites

2.5 out of 5
2228 Asheville Hwy, Brevard, NC
  • 1 hour drive from Lake Keowee
Stay at this hotel in Brevard. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Comfort Inn & Suites
Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area

2.5 out of 5
851 Tiger Blvd, Clemson, SC
  • 22 min drive from Lake Keowee
Stay at this hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Larry W. Abernathy Waterfront Park and Littlejohn Coliseum ...
Hampton Inn Clemson-University Area
Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG

2.5 out of 5
1381 Tiger Blvd, Clemson, SC
  • 25 min drive from Lake Keowee
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express & Suites Clemson by IHG
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3 out of 5
240 Madren Center Drive, Clemson, SC
  • 26 min drive from Lake Keowee
Stay at this 3-star golf hotel in Clemson. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our ...
Clemson University's James F. Martin Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Salem

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Salem.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Salem’s 3,187 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $99. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Salem hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Salem. No matter your reason for visiting Salem, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Salem hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Salem for as low as $99.

How many hotels are there in Salem?

With over 3,187 hotels in Salem, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $99.

How to find cheap car rentals in Salem?

Finding a cheap car rental deal in Salem is as easy as scoring cheap hotels in Salem. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.