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Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
  • 24 min drive from Lake Keowee
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,001 reviews)
"Not bad for a quick weekend stay."

Reviewed on Jun 24, 2026

Best Western Plus Clemson Hotel & Conference Center
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
  • 24 min drive from Lake Keowee
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.8/10 Exceptional! (824 reviews)
"The Staff and service were top notch."

Reviewed on Jun 25, 2026

The Shepherd Hotel Downtown Clemson
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
  • 21 min drive from Lake Keowee
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (1,002 reviews)
"It's in a beautiful location and is a wonderful property.One of the best in the area. If you would like a condo setting or kitchenettes, I highly recommend lakeside lodge."

Reviewed on Jun 26, 2026

Lakeside Lodge Clemson
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd Clemson SC
  • 24 min drive from Lake Keowee
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,000 reviews)
"The breakfast was a bust. No milk for the cereal and no waffle mix. And this was on a Saturday morning!"

Reviewed on Jun 21, 2026

Inn @ Clemson
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
  • 23 min drive from Lake Keowee
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (720 reviews)
"I liked the cleanliness in the room and the pool area. Fresh towels were given each day. It was a nice place to stay."

Reviewed on Jun 21, 2026

Quality Inn Seneca Clemson Area US-123
Trailborn Highlands, Outdoor Collection by Marriott Bonvoy

Trailborn Highlands, Outdoor Collection by Marriott Bonvoy

4 out of 5
96 Log Cabin Lane Highlands NC
  • 1 hour drive from Lake Keowee
Stay at this hotel in Highlands. Enjoy free parking, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (308 reviews)
"Clean and well maintained property. Helpful staff. Easy walk to downtown Highlands. Comfortable room. Morning coffee and tea service was very basic. This could be improved. Perhaps provide more coffee options and a pastry or two."

Reviewed on Jun 26, 2026

Trailborn Highlands, Outdoor Collection by Marriott Bonvoy
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
  • 24 min drive from Lake Keowee
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,004 reviews)
"Had a great stay"

Reviewed on Jun 26, 2026

Comfort Inn & Suites Clemson - University Area
Courtyard Marriott Clemson

Courtyard Marriott Clemson

3 out of 5
201 Canoy Ln Clemson SC
  • 25 min drive from Lake Keowee
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Memorial Stadium and Clemson ...
9/10 Wonderful! (547 reviews)
"Great friendly staff."

Reviewed on Jun 17, 2026

Courtyard Marriott Clemson
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3 out of 5
240 Madren Center Drive Clemson SC
  • 26 min drive from Lake Keowee
Book a stay at this golf hotel in Clemson. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our ...
9.4/10 Exceptional! (1,000 reviews)
"Very nice, very clean. Best hotel in clemson"

Reviewed on Jun 24, 2026

Clemson University's James F. Martin Inn
Fairway Forest

Fairway Forest

3.5 out of 5
70 Sapphire Valley Road Sapphire NC
  • 57 min drive from Lake Keowee
Book a stay at this golf hotel in Sapphire. Enjoy 2 outdoor pools, hot springs on site, and a sauna. Popular attractions Sapphire Valley Ski Resort and Sapphire ...
8.8/10 Excellent! (361 reviews)
"The property was very clean and very accommodating. No complaints at all."

Reviewed on Jun 26, 2026

Fairway Forest
The Inn at Patrick Square

The Inn at Patrick Square

3.5 out of 5
115 Market Street Clemson SC
  • 28 min drive from Lake Keowee
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and ...
9.8/10 Exceptional! (869 reviews)
"Very nice hotel. Clean and beautifully maintained."

Reviewed on Jun 24, 2026

The Inn at Patrick Square
Comfort Inn & Suites Brevard North

Comfort Inn & Suites Brevard North

2.5 out of 5
2228 Asheville Hwy Brevard NC
  • 1 hour drive from Lake Keowee
Stay at this hotel in Brevard. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,000 reviews)
"Clean rooms and bathroom, close to restaurants, decent breakfast"

Reviewed on Jun 23, 2026

Comfort Inn & Suites Brevard North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Salem

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $94. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Salem hotel deals at the last minute.

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Frequently Asked Questions About Salem hotels

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How many hotels are there in Salem?

With over 3,296 hotels in Salem, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $94.

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