Search Cheap Flights to
Seneca

Photo by Cindy Keese

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Seneca Flights as Low as $177

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Delta
Delta
Delta
Delta
Delta
United
American Airlines
Bargain Flight
Delta
Bargain Flight
Bargain Flight
American Airlines
Bargain Flight
Delta
Alaska Airlines

Cheap Flights to Seneca

Fall in love at first flight with your vacation to Seneca by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Seneca on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Seneca, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Seneca

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Seneca with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Seneca?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Seneca are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Seneca?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 12 to choose from for your flight to Seneca.

What airport is best to fly into Seneca?

When you’re planning your trip to Seneca, convenience is the name of the game. Luckily, Seneca Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Seneca must-do list.

How much are flights to Seneca?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Seneca on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $177, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Seneca?

The trick to saving a stack of cash on your flight to Seneca? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $177 right now, why wait?

Seneca Flight Information
Destination airport
Greenville-Spartanburg Intl.
Destination airport IATA code
GSP
Roundtrip price
$176

Last Minute Hotel Deals in Seneca

Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (888 reviews)
"A beautiful property with every amenity a body could want. The staff is friendly and helpful. The room was exceptionallly clean and very spacious. I give the Lakeside Lodge 6 stars."

Reviewed on May 31, 2025

Lakeside Lodge Clemson
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 out of 5
13050 Clemson Blvd, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (720 reviews)
"Great place to stay, Hannah at the front desk was fabulous!"

Reviewed on Jun 2, 2025

Tru by Hilton Seneca Clemson
Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123
2.5 out of 5
226 Hi Tech Rd, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (592 reviews)
"I’ve stayed here several times and never was disappointed."

Reviewed on Jun 1, 2025

Quality Inn Seneca Clemson Area US-123
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 out of 5
1011 East North 1st Street, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (601 reviews)
"Clean comfortable room in a good location with a nice breakfast and a friendly staff. Checks all the boxes!"

Reviewed on Jun 2, 2025

Hampton Inn & Suites Seneca-Clemson Area
Best Western Seneca-Clemson
Best Western Seneca-Clemson
2.5 out of 5
511 Bypass Highway 123, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (590 reviews)
Lb
"Room was very clean. Easy to get to room. They pickup the trash and gave us clean linens while we were gone didnt notice they were there. The only thing that was disapointing was the pool was closed"

Reviewed on May 27, 2025

Best Western Seneca-Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 out of 5
800 BYPASS 123, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (156 reviews)
"The breakfast was really good. The room was clean and staff was nice. When we checked in, there was no soup nor hank wash provided. The air conditioner was very loud in the evening. When I adjusted the room temperature from 74 degrees to 72 degrees, it took more than one hour and didn’t reach the ..."

Reviewed on May 25, 2025

Fairfield Inn & Suites Seneca Clemson Univ Area
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
2 out of 5
11015 N Radio Station Rd, Seneca, SC
Stay at this motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Applewood ...
6.8/10 (682 reviews)
"Clean and comfortable. Good location. Close to Clemson University"

Reviewed on May 9, 2025

Days Inn by Wyndham Seneca / Clemson Area
Postcard Cabins Lake Hartwell
Postcard Cabins Lake Hartwell
2 out of 5
299 Outpost Rd, Seneca, SC
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
10/10 Exceptional! (7 reviews)
"great getaway. comfortable accommodations"

Reviewed on May 16, 2025

Postcard Cabins Lake Hartwell
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.