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Seneca

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Seneca Flights as Low as $159

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Breeze Airways
Fri, Jul 10 - Sun, Jul 12
TPA
Tampa Intl.
GSP
Greenville-Spartanburg Intl.
$159 Roundtrip, found 2 hours ago
$159
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Fri, Jul 10 from Tampa Intl. to Greenville-Spartanburg Intl., returning Sun, Jul 12, priced at $159 found 2 hours ago
Breeze Airways
Fri, Jul 10 - Sun, Jul 12
TPA
Tampa Intl.
GSP
Greenville-Spartanburg Intl.
$162 Roundtrip, found 2 hours ago
$162
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Fri, Jul 10 from Tampa Intl. to Greenville-Spartanburg Intl., returning Sun, Jul 12, priced at $162 found 2 hours ago
Breeze Airways
Fri, Jul 10 - Sun, Jul 12
TPA
Tampa Intl.
GSP
Greenville-Spartanburg Intl.
$164 Roundtrip, found 2 hours ago
$164
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Fri, Jul 10 from Tampa Intl. to Greenville-Spartanburg Intl., returning Sun, Jul 12, priced at $164 found 2 hours ago
Breeze Airways
Fri, Aug 28 - Sun, Aug 30
TPA
Tampa Intl.
GSP
Greenville-Spartanburg Intl.
$165 Roundtrip, found 2 days ago
$165
Roundtrip
found 2 days ago
Select Breeze Airways flight, departing Fri, Aug 28 from Tampa Intl. to Greenville-Spartanburg Intl., returning Sun, Aug 30, priced at $165 found 2 days ago
Breeze Airways
Fri, Jul 10 - Sun, Jul 12
TPA
Tampa Intl.
GSP
Greenville-Spartanburg Intl.
$170 Roundtrip, found 2 hours ago
$170
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Fri, Jul 10 from Tampa Intl. to Greenville-Spartanburg Intl., returning Sun, Jul 12, priced at $170 found 2 hours ago
Bargain Flight
Wed, Aug 26 - Tue, Sep 15
RIC
Richmond Intl.
GSP
Greenville-Spartanburg Intl.
$202 Roundtrip, found 1 day ago
$202
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Wed, Aug 26 from Richmond Intl. to Greenville-Spartanburg Intl., returning Tue, Sep 15, priced at $202 found 1 day ago
Delta
Fri, Aug 28 - Sun, Aug 30
TPA
Tampa Intl.
GSP
Greenville-Spartanburg Intl.
$229 Roundtrip, found 2 days ago
$229
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Aug 28 from Tampa Intl. to Greenville-Spartanburg Intl., returning Sun, Aug 30, priced at $229 found 2 days ago
American Airlines
Wed, Aug 26 - Tue, Sep 15
RIC
Richmond Intl.
GSP
Greenville-Spartanburg Intl.
$289 Roundtrip, found 1 day ago
$289
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Aug 26 from Richmond Intl. to Greenville-Spartanburg Intl., returning Tue, Sep 15, priced at $289 found 1 day ago
Delta
Tue, Aug 11 - Sat, Aug 15
PHX
Sky Harbor Intl.
GSP
Greenville-Spartanburg Intl.
$301 Roundtrip, found 15 hours ago
$301
Roundtrip
found 15 hours ago
Select Delta flight, departing Tue, Aug 11 from Sky Harbor Intl. to Greenville-Spartanburg Intl., returning Sat, Aug 15, priced at $301 found 15 hours ago
American Airlines
Tue, Aug 11 - Tue, Aug 18
MSP
Minneapolis - St. Paul Intl.
GSP
Greenville-Spartanburg Intl.
$317 Roundtrip, found 4 days ago
$317
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Aug 11 from Minneapolis - St. Paul Intl. to Greenville-Spartanburg Intl., returning Tue, Aug 18, priced at $317 found 4 days ago
American Airlines
Tue, Aug 4 - Tue, Aug 11
COS
Colorado Springs
GSP
Greenville-Spartanburg Intl.
$319 Roundtrip, found 1 day ago
$319
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Aug 4 from Colorado Springs to Greenville-Spartanburg Intl., returning Tue, Aug 11, priced at $319 found 1 day ago
Delta
Sat, Aug 29 - Tue, Sep 15
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$331 Roundtrip, found 19 hours ago
$331
Roundtrip
found 19 hours ago
Select Delta flight, departing Sat, Aug 29 from LaGuardia to Greenville-Spartanburg Intl., returning Tue, Sep 15, priced at $331 found 19 hours ago
Bargain Flight
Fri, Sep 4 - Tue, Sep 8
DTW
Detroit Metropolitan Wayne County
GSP
Greenville-Spartanburg Intl.
$337 Roundtrip, found 22 hours ago
$337
Roundtrip
found 22 hours ago
Select Bargain Flight flight, departing Fri, Sep 4 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Tue, Sep 8, priced at $337 found 22 hours ago
Bargain Flight
Tue, Jul 14 - Wed, Jul 15
AUS
Austin-Bergstrom Intl.
GSP
Greenville-Spartanburg Intl.
$379 Roundtrip, found 2 days ago
$379
Roundtrip
found 2 days ago
Select Bargain Flight flight, departing Tue, Jul 14 from Austin-Bergstrom Intl. to Greenville-Spartanburg Intl., returning Wed, Jul 15, priced at $379 found 2 days ago
American Airlines
Tue, Jun 30 - Tue, Jul 7
HPN
Westchester County
GSP
Greenville-Spartanburg Intl.
$499 Roundtrip, found 1 day ago
$499
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 30 from Westchester County to Greenville-Spartanburg Intl., returning Tue, Jul 7, priced at $499 found 1 day ago
Delta
Sun, Jul 5 - Thu, Jul 9
SAT
San Antonio Intl.
GSP
Greenville-Spartanburg Intl.
$737 Roundtrip, found 1 day ago
$737
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Jul 5 from San Antonio Intl. to Greenville-Spartanburg Intl., returning Thu, Jul 9, priced at $737 found 1 day ago

Cheap Flights to Seneca

Fall in love at first flight with your vacation to Seneca by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Seneca on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Seneca, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Seneca

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Seneca with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Seneca?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Seneca are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Seneca?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Seneca.

What airport is best to fly into Seneca?

When you’re planning your trip to Seneca, convenience is the name of the game. Luckily, Seneca Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Seneca must-do list.

How much are flights to Seneca?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Seneca on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $159, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Seneca?

The trick to saving a stack of cash on your flight to Seneca? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $159 right now, why wait?

Seneca Flight Information
Destination airport
Greenville-Spartanburg Intl.
Destination airport IATA code
GSP
Roundtrip price
$159

Last Minute Hotel Deals in Seneca

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (1,002 reviews)
"It's in a beautiful location and is a wonderful property.One of the best in the area. If you would like a condo setting or kitchenettes, I highly recommend lakeside lodge."

Reviewed on Jun 26, 2026

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Lakeside Lodge Clemson
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (720 reviews)
"I liked the cleanliness in the room and the pool area. Fresh towels were given each day. It was a nice place to stay."

Reviewed on Jun 21, 2026

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Quality Inn Seneca Clemson Area US-123
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
9.8/10 Exceptional! (80 reviews)
"This cabin is SMALL and it is well appointed and feels bigger than it is because of the very high ceilings. The bed was comfortable, the room was very clean, the bathroom products smelled good, and the treats were a nice touch. My only real complaint is that we were supposed to receive a text the ..."

Reviewed on Jun 20, 2026

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Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

3 out of 5
800 BYPASS 123 Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (240 reviews)
"The lake view was very nice."

Reviewed on Jun 25, 2026

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Fairfield Inn & Suites Seneca Clemson Univ Area
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (857 reviews)
"We recently visited Clemson University and found this hotel to be the perfect location. It was conveniently close to the university, with a variety of dining options nearby. The room was clean and spacious, and we appreciated the nice variety offered at breakfast. The staff were excellent, and the ..."

Reviewed on Jun 27, 2026

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Tru by Hilton Seneca Clemson
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (725 reviews)
"This was my first stay at this location, and I can definitely say that I will be back. The staff was very kind and helpful before, during, and even after the stay. The hotel was very neat and clean, and the rooms were very comfy! The hotel is also in an area close to stores and other amenities."

Reviewed on Jun 16, 2026

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Hampton Inn & Suites Seneca-Clemson Area
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2 out of 5
11015 N Radio Station Rd Seneca SC
Stay at this motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Applewood ...
6.8/10 (753 reviews)
"To start, I thought the staff was very professional, friendly and helpful. My room was very clean and tidy, and everything was working in order. I guess if I had one small complaint it would be the.selection for breakfast, a larger selection of fruits and maybe some danish / donuts / yogurt would ..."

Reviewed on Jun 14, 2026

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Days Inn by Wyndham Seneca / Clemson Area
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 out of 5
511 Bypass Highway 123 Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (669 reviews)
"We didn't like that the AC outside drain was clogged so the water stayed inside the room and made the carpet soggy so the room smelled musty. Staff said they have no maintenance personnel currently. 🤔"

Reviewed on Jun 25, 2026

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Best Western Seneca-Clemson
See all 1,664 properties in Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.