Search Cheap Flights to
Seneca

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Cheap Flights to Seneca

Fall in love at first flight with your vacation to Seneca by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Seneca on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Seneca, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Seneca

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Seneca with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Seneca?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Seneca are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Seneca?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Seneca.

What airport is best to fly into Seneca?

When you’re planning your trip to Seneca, convenience is the name of the game. Luckily, Seneca Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Seneca must-do list.

How much are flights to Seneca?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Seneca on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Seneca?

The trick to saving a stack of cash on your flight to Seneca? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Seneca Flight Information
Destination airport
Seneca
Destination airport IATA code
GSP

Last Minute Hotel Deals in Seneca

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (659 reviews)
Clean room w fridge and microwave Comfy bed

Reviewed on Nov 15, 2025

Quality Inn Seneca Clemson Area US-123
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (1,002 reviews)
Easy checkin, clean and plenty of space!

Reviewed on Nov 17, 2025

Lakeside Lodge Clemson
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2 out of 5
11015 N Radio Station Rd Seneca SC
Stay at this motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Applewood ...
6.8/10 (714 reviews)
Clean, friendly.. great service and lots to do

Reviewed on Oct 28, 2025

Days Inn by Wyndham Seneca / Clemson Area
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 out of 5
511 Bypass Highway 123 Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (630 reviews)
The hotel was quiet and the room was very clean and spacious. The mattress was comfortable and the water pressure in the shower was great. They provide free breakfast and leave out some snacks and coffee out all the time which was very nice. The price was very reasonable, especially for a Clemson ...

Reviewed on Nov 11, 2025

Best Western Seneca-Clemson
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (781 reviews)
Stayed one night for visit with Son at Clemson, everything was good, friendly staff, clean room and good breakfast.

Reviewed on Oct 28, 2025

Tru by Hilton Seneca Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 out of 5
800 BYPASS 123 Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (203 reviews)
Very

Reviewed on Oct 18, 2025

Fairfield Inn & Suites Seneca Clemson Univ Area
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (654 reviews)
Would have liked to see more fruit or gluten free options available for breakfast.

Reviewed on Nov 7, 2025

Hampton Inn & Suites Seneca-Clemson Area
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
9.6/10 Exceptional! (46 reviews)
The cabin was very cozy.

Reviewed on Nov 4, 2025

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.