Hotels with Early Check-in in
Upstate South Carolina

Check Last Minute Upstate South Carolina Hotel Deals

Tonight Mar 25 - Mar 26This weekend Mar 28 - Mar 30Next weekend Apr 4 - Apr 6

Featured Upstate South Carolina Hotels with Early Check-in

Holiday Inn Express & Suites Greenville - Downtown by IHG
Holiday Inn Express & Suites Greenville - Downtown by IHG
2.5 out of 5
407 North Main Street, Greenville, SC
The price is $134 per night from Apr 6 to Apr 7
$134
includes taxes & fees
Apr 6 - Apr 7
Holiday Inn Express & Suites Greenville - Downtown by IHG
Holiday Inn Anderson by IHG
Holiday Inn Anderson by IHG
3 out of 5
3509 Clemson Blvd, Anderson, SC
The price is $134 per night from Apr 13 to Apr 14
$134
includes taxes & fees
Apr 13 - Apr 14
Holiday Inn Anderson by IHG
Best Western Greenville Airport Inn
Best Western Greenville Airport Inn
2.5 out of 5
5009 Pelham Road, Greenville, SC
The price is $90 per night from Mar 30 to Mar 31
$90
includes taxes & fees
Mar 30 - Mar 31
Best Western Greenville Airport Inn
Hampton Inn Gaffney
Hampton Inn Gaffney
2.5 out of 5
115 Nancy Creek Rd, Gaffney, SC
The price is $112 per night from Apr 11 to Apr 12
$112
includes taxes & fees
Apr 11 - Apr 12
Hampton Inn Gaffney
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Upstate South Carolina

South Carolina is a city that has a lot going on, but you have your sights set on Upstate South Carolina. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Upstate South Carolina has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Upstate South Carolina hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of South Carolina so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Upstate South Carolina underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Upstate South Carolina city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Upstate South Carolina cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Upstate South Carolina at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $90
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Upstate South Carolina hotel you want, book it, and never look back. Because your great escape is ahead of you.