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Cayos Zapatilla Vacation Packages

Build your package with 2 more options

Cayos Zapatilla Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,101, price is now $797 per person
$797
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $1,711, price is now $876 per person
$876
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Nice hotel. Great location. Good breakfast. Our only complaint is about noise. The hotel has live music in the atrium from early in the morning until about 10 pm. Our room, along with many others, had windows facing into the atrium, and the noise from the music, and sometimes large tour groups at breakfast, may disturb your sleep.

Reviewed on Aug 10, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,395, price is now $832 per person
$832
per person
Oct 15 - Oct 18
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
The room smelled like humid, and it was actually very humid, the walls in the bathroom where super dirty, housekeeping came in 2 times in our 6 night stay. We had to change room because of the smell.

Reviewed on Aug 11, 2026

Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Price was $1,139, price is now $813 per person
$813
per person
Oct 6 - Oct 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Price was $1,179, price is now $854 per person
$854
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Limpio, personal servicial

Reviewed on Aug 11, 2026

Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Price was $1,707, price is now $1,251 per person
$1,251
per person
Oct 22 - Oct 26
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Well appointed, friendly staff on site and excellent location. Noise from the outside does get in but it didnt bother us too much. Would definitely stay again!

Reviewed on Jul 28, 2026

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,257, price is now $934 per person
$934
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Buena alternativa para descansar y a pocos minutos del aeropuerto.

Reviewed on Aug 9, 2026

san blas luxury tour

san blas luxury tour

2 out of 5
Price was $1,290, price is now $963 per person
$963
per person
Oct 12 - Oct 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, free WiFi, and a private beach.

Cayos Zapatilla Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,101, price is now $797 per person
$797
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,711, price is now $876 per person
$876
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,395, price is now $832 per person
$832
per person
Oct 15 - Oct 18
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
San Francisco
Price was $1,139, price is now $813 per person
$813
per person
Oct 6 - Oct 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

Cayos Zapatilla Vacation Packages 5-7 Night Stays

Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,736, price is now $1,012 per person
$1,012
per person
Oct 29 - Nov 3
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Save 100% on your flight
Price was $2,293, price is now $1,259 per person
$1,259
per person
Oct 2 - Oct 8
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,518, price is now $1,034 per person
$1,034
per person
Oct 2 - Oct 8
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
San Francisco
Price was $1,500, price is now $1,028 per person
$1,028
per person
Oct 2 - Oct 8
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Tue, Oct 20 - Sun, Oct 25
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$243 Roundtrip, found 3 hours ago
$243
Roundtrip
found 3 hours ago
Select Copa flight, departing Tue, Oct 20 from Juan Santamaría Intl. to Tocumen Intl., returning Sun, Oct 25, priced at $243 found 3 hours ago
American Airlines
Sat, Oct 31 - Mon, Nov 9
MIA
Miami Intl.
PTY
Tocumen Intl.
$416 Roundtrip, found 1 hour ago
$416
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, Oct 31 from Miami Intl. to Tocumen Intl., returning Mon, Nov 9, priced at $416 found 1 hour ago
Copa
Sat, Oct 3 - Tue, Oct 6
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$496 Roundtrip, found 23 hours ago
$496
Roundtrip
found 23 hours ago
Select Copa flight, departing Sat, Oct 3 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Tue, Oct 6, priced at $496 found 23 hours ago
Delta
Mon, Jan 11 - Thu, Jan 21
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$590 Roundtrip, found 23 hours ago
$590
Roundtrip
found 23 hours ago
Select Delta flight, departing Mon, Jan 11 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Thu, Jan 21, priced at $590 found 23 hours ago