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Irene

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Irene Flights as Low as $129

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Jul 30 - Wed, Aug 6
DEN
Denver Intl.
FSD
Sioux Falls Regional
$129 Roundtrip, found 17 hours ago
$129
Roundtrip
found 17 hours ago
Select Frontier Airlines flight, departing Wed, Jul 30 from Denver Intl. to Sioux Falls Regional, returning Wed, Aug 6, priced at $129 found 17 hours ago
United
Tue, Aug 26 - Sun, Aug 31
DEN
Denver Intl.
FSD
Sioux Falls Regional
$186 Roundtrip, found 8 hours ago
$186
Roundtrip
found 8 hours ago
Select United flight, departing Tue, Aug 26 from Denver Intl. to Sioux Falls Regional, returning Sun, Aug 31, priced at $186 found 8 hours ago
United
Thu, Oct 9 - Sun, Oct 12
DEN
Denver Intl.
SUX
Sioux Gateway
$214 Roundtrip, found 10 hours ago
$214
Roundtrip
found 10 hours ago
Select United flight, departing Thu, Oct 9 from Denver Intl. to Sioux Gateway, returning Sun, Oct 12, priced at $214 found 10 hours ago
American Airlines
Sun, Aug 31 - Wed, Sep 3
IAH
George Bush Intercontinental
FSD
Sioux Falls Regional
$226 Roundtrip, found 4 hours ago
$226
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sun, Aug 31 from George Bush Intercontinental to Sioux Falls Regional, returning Wed, Sep 3, priced at $226 found 4 hours ago
United
Tue, Aug 26 - Tue, Sep 2
IAH
George Bush Intercontinental
SUX
Sioux Gateway
$236 Roundtrip, just found
$236
Roundtrip
just found
Select United flight, departing Tue, Aug 26 from George Bush Intercontinental to Sioux Gateway, returning Tue, Sep 2, priced at $236 just found
Bargain Flight
Fri, Nov 14 - Mon, Nov 17
DCA
Ronald Reagan Washington National
FSD
Sioux Falls Regional
$240 Roundtrip, found 15 hours ago
$240
Roundtrip
found 15 hours ago
Select Bargain Flight flight, departing Fri, Nov 14 from Ronald Reagan Washington National to Sioux Falls Regional, returning Mon, Nov 17, priced at $240 found 15 hours ago
United
Wed, Sep 24 - Tue, Sep 30
DCA
Ronald Reagan Washington National
SUX
Sioux Gateway
$244 Roundtrip, found 9 hours ago
$244
Roundtrip
found 9 hours ago
Select United flight, departing Wed, Sep 24 from Ronald Reagan Washington National to Sioux Gateway, returning Tue, Sep 30, priced at $244 found 9 hours ago
Bargain Flight
Tue, Aug 5 - Tue, Aug 19
MSY
Louis Armstrong New Orleans Intl.
FSD
Sioux Falls Regional
$249 Roundtrip, found 12 hours ago
$249
Roundtrip
found 12 hours ago
Select Bargain Flight flight, departing Tue, Aug 5 from Louis Armstrong New Orleans Intl. to Sioux Falls Regional, returning Tue, Aug 19, priced at $249 found 12 hours ago
Delta
Sat, Aug 16 - Sun, Aug 17
BUF
Buffalo Niagara Intl.
FSD
Sioux Falls Regional
$259 Roundtrip, found 2 days ago
$259
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Aug 16 from Buffalo Niagara Intl. to Sioux Falls Regional, returning Sun, Aug 17, priced at $259 found 2 days ago
American Airlines
Tue, Nov 4 - Sun, Nov 9
CHA
Chattanooga Metropolitan
FSD
Sioux Falls Regional
$268 Roundtrip, found 4 hours ago
$268
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Nov 4 from Chattanooga Metropolitan to Sioux Falls Regional, returning Sun, Nov 9, priced at $268 found 4 hours ago
Bargain Flight
Fri, Jul 25 - Sun, Jul 27
RNO
Reno-Tahoe Intl.
FSD
Sioux Falls Regional
$274 Roundtrip, just found
$274
Roundtrip
just found
Select Bargain Flight flight, departing Fri, Jul 25 from Reno-Tahoe Intl. to Sioux Falls Regional, returning Sun, Jul 27, priced at $274 just found
Frontier Airlines
Wed, Jul 30 - Fri, Aug 1
DFW
Dallas-Fort Worth Intl.
FSD
Sioux Falls Regional
$277 Roundtrip, found 1 day ago
$277
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Jul 30 from Dallas-Fort Worth Intl. to Sioux Falls Regional, returning Fri, Aug 1, priced at $277 found 1 day ago
Frontier Airlines
Wed, Aug 6 - Wed, Aug 13
ATL
Hartsfield-Jackson Atlanta Intl.
FSD
Sioux Falls Regional
$286 Roundtrip, found 1 day ago
$286
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Aug 6 from Hartsfield-Jackson Atlanta Intl. to Sioux Falls Regional, returning Wed, Aug 13, priced at $286 found 1 day ago
Delta
Tue, Sep 30 - Sat, Oct 4
DAL
Love Field
FSD
Sioux Falls Regional
$342 Roundtrip, found 7 hours ago
$342
Roundtrip
found 7 hours ago
Select Delta flight, departing Tue, Sep 30 from Love Field to Sioux Falls Regional, returning Sat, Oct 4, priced at $342 found 7 hours ago
United
Fri, Aug 8 - Tue, Aug 12
DFW
Dallas-Fort Worth Intl.
SUX
Sioux Gateway
$395 Roundtrip, found 10 hours ago
$395
Roundtrip
found 10 hours ago
Select United flight, departing Fri, Aug 8 from Dallas-Fort Worth Intl. to Sioux Gateway, returning Tue, Aug 12, priced at $395 found 10 hours ago
Delta
Fri, Aug 8 - Tue, Aug 12
DAL
Love Field
SUX
Sioux Gateway
$1,319 Roundtrip, found 2 days ago
$1,319
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Aug 8 from Love Field to Sioux Gateway, returning Tue, Aug 12, priced at $1,319 found 2 days ago

Cheap Flights to Irene

Fall in love at first flight with your vacation to Irene by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Irene on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Irene, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Irene

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Irene with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the YKN airport.

What is the cheapest month to fly to Irene?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Irene are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Irene?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Irene.

What airport is best to fly into Irene?

When you’re planning your trip to Irene, convenience is the name of the game. Luckily, Irene Sioux Falls Regional Airport is nearby so you can deplane and get going on checking off everything on your Irene must-do list.

How much are flights to Irene?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Irene on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $129, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Irene?

The trick to saving a stack of cash on your flight to Irene? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $129 right now, why wait?

Irene Flight Information
Destination airport
Sioux Falls Regional
Destination airport IATA code
FSD
Roundtrip price
$128

Last Minute Hotel Deals in Irene

Yankton Inn

Yankton Inn

2 out of 5
1603 East Highway 50, Yankton, SD
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (225 reviews)
Impressive for newly renovated motel
"Overall, it was quite good for the newly renovated motel, which previously resembled a Super 8. Everything is very convenient. Just that the water pressure for the shower might need some gain. :-)"

Reviewed on Jul 7, 2025

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Yankton Inn
Best Western Kelly Inn

Best Western Kelly Inn

2.5 out of 5
1607 E Highway 50, Yankton, SD
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (607 reviews)
"It was clean. I had a leak in my room and the help was really nice. Maintenance came and looked into right away."

Reviewed on Jul 7, 2025

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Best Western Kelly Inn
Lewis and Clark Resort

Lewis and Clark Resort

2.5 out of 5
43496 Shore Drive, Yankton, SD
Book a stay at this beach hotel in Yankton. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Lewis and Clark Recreation Area and Midway ...
8.6/10 Excellent! (229 reviews)
"Beautiful place, rooms are very outdated but at least clean. Very friendly staff and beautiful beaches"

Reviewed on Jul 3, 2025

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Lewis and Clark Resort
Econo Lodge Inn & Suites

Econo Lodge Inn & Suites

2 out of 5
2410 Broadway Ave, Yankton, SD
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fox Run Plaza and Augusta Park ...
7.2/10 Good! (665 reviews)
"The workers were delightful and very friendly. The rooms were adequate. Actually ironically the toilet paper was superb which is a funny way to judge how much a hotel cares about you. But maintenance of the place is very poor. The rugs are disgusting. The pool though indoor wasn't even heated. The ..."

Reviewed on Jun 22, 2025

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Econo Lodge Inn & Suites
Fairfield Inn & Suites by Marriott Yankton

Fairfield Inn & Suites by Marriott Yankton

2.5 out of 5
508 WEST 21ST STREET, Yankton, SD
Stay at this hotel in Yankton. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (134 reviews)
Comfortable Room
"Room was clean and bed was comfortable. Breakfast area was nice sized. The area seemed cool. Would like them to offer flavor creamers and whole milk."

Reviewed on Jul 18, 2025

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Fairfield Inn & Suites by Marriott Yankton
Comfort Inn Yankton SD

Comfort Inn Yankton SD

2.5 out of 5
611 W 23rd Street, Yankton, SD
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (612 reviews)
"Loved it here. Super safe and great staff."

Reviewed on Jul 7, 2025

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Comfort Inn Yankton SD
Holiday Inn Express & Suites Yankton by IHG

Holiday Inn Express & Suites Yankton by IHG

2.5 out of 5
2607 Broadway Ave, Yankton, SD
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (398 reviews)
Amazing
"Amazingly clean and comfortable"

Reviewed on Jul 18, 2025

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Holiday Inn Express & Suites Yankton by IHG
Super 8 by Wyndham Beresford

Super 8 by Wyndham Beresford

2 out of 5
1410 W Cedar St, Hwy 46 & I-29, Beresford, SD
Book a stay at this business-friendly motel in Beresford. Enjoy free breakfast, free WiFi, and free parking.
6.2/10 (262 reviews)
"Very clean, friendly and helpful."

Reviewed on Jun 13, 2025

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Super 8 by Wyndham Beresford
See all 79 properties in Irene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.