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Irene

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Irene Flights as Low as $242

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Sun, Jun 15 - Tue, Jul 1
FWA
Fort Wayne Intl.
FSD
Sioux Falls Regional
$242 Roundtrip, found 2 days ago
$242
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, Jun 15 from Fort Wayne Intl. to Sioux Falls Regional, returning Tue, Jul 1, priced at $242 found 2 days ago
Delta
Tue, Jun 17 - Tue, Jul 1
FWA
Fort Wayne Intl.
FSD
Sioux Falls Regional
$247 Roundtrip, found 2 days ago
$247
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jun 17 from Fort Wayne Intl. to Sioux Falls Regional, returning Tue, Jul 1, priced at $247 found 2 days ago
United
Thu, Sep 4 - Mon, Sep 8
ORD
O'Hare Intl.
FSD
Sioux Falls Regional
$249 Roundtrip, found 5 hours ago
$249
Roundtrip
found 5 hours ago
Select United flight, departing Thu, Sep 4 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Sep 8, priced at $249 found 5 hours ago
American Airlines
Thu, Sep 4 - Mon, Sep 8
ORD
O'Hare Intl.
FSD
Sioux Falls Regional
$249 Roundtrip, found 5 hours ago
$249
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Thu, Sep 4 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Sep 8, priced at $249 found 5 hours ago
United
Fri, Jun 20 - Sun, Jun 29
FWA
Fort Wayne Intl.
FSD
Sioux Falls Regional
$253 Roundtrip, found 4 hours ago
$253
Roundtrip
found 4 hours ago
Select United flight, departing Fri, Jun 20 from Fort Wayne Intl. to Sioux Falls Regional, returning Sun, Jun 29, priced at $253 found 4 hours ago
Delta
Tue, Jun 17 - Sun, Jun 29
FWA
Fort Wayne Intl.
FSD
Sioux Falls Regional
$258 Roundtrip, found 1 day ago
$258
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jun 17 from Fort Wayne Intl. to Sioux Falls Regional, returning Sun, Jun 29, priced at $258 found 1 day ago
Delta
Sat, Jul 19 - Wed, Jul 23
RDU
Raleigh - Durham Intl.
FSD
Sioux Falls Regional
$259 Roundtrip, found 23 hours ago
$259
Roundtrip
found 23 hours ago
Select Delta flight, departing Sat, Jul 19 from Raleigh - Durham Intl. to Sioux Falls Regional, returning Wed, Jul 23, priced at $259 found 23 hours ago
American Airlines
Thu, Sep 4 - Mon, Sep 8
ORD
O'Hare Intl.
FSD
Sioux Falls Regional
$259 Roundtrip, found 5 hours ago
$259
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Thu, Sep 4 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Sep 8, priced at $259 found 5 hours ago
Frontier Airlines
Mon, Sep 1 - Fri, Sep 5
ORD
O'Hare Intl.
FSD
Sioux Falls Regional
$260 Roundtrip, found 5 hours ago
$260
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Mon, Sep 1 from O'Hare Intl. to Sioux Falls Regional, returning Fri, Sep 5, priced at $260 found 5 hours ago
Bargain Flight
Wed, May 14 - Tue, May 20
PSP
Palm Springs Intl.
FSD
Sioux Falls Regional
$275 Roundtrip, found 9 hours ago
$275
Roundtrip
found 9 hours ago
Select Bargain Flight flight, departing Wed, May 14 from Palm Springs Intl. to Sioux Falls Regional, returning Tue, May 20, priced at $275 found 9 hours ago
United
Fri, May 30 - Tue, Jun 3
MDT
Harrisburg Intl.
FSD
Sioux Falls Regional
$339 Roundtrip, found 8 hours ago
$339
Roundtrip
found 8 hours ago
Select United flight, departing Fri, May 30 from Harrisburg Intl. to Sioux Falls Regional, returning Tue, Jun 3, priced at $339 found 8 hours ago
American Airlines
Sat, May 17 - Tue, May 20
TLH
Tallahassee Intl.
FSD
Sioux Falls Regional
$352 Roundtrip, found 18 hours ago
$352
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Sat, May 17 from Tallahassee Intl. to Sioux Falls Regional, returning Tue, May 20, priced at $352 found 18 hours ago
Delta
Mon, May 12 - Sat, May 17
GSP
Greenville-Spartanburg Intl.
FSD
Sioux Falls Regional
$379 Roundtrip, found 4 hours ago
$379
Roundtrip
found 4 hours ago
Select Delta flight, departing Mon, May 12 from Greenville-Spartanburg Intl. to Sioux Falls Regional, returning Sat, May 17, priced at $379 found 4 hours ago
United
Sat, May 10 - Mon, May 12
MEM
Memphis Intl.
FSD
Sioux Falls Regional
$446 Roundtrip, found 21 hours ago
$446
Roundtrip
found 21 hours ago
Select United flight, departing Sat, May 10 from Memphis Intl. to Sioux Falls Regional, returning Mon, May 12, priced at $446 found 21 hours ago
United
Wed, May 14 - Tue, May 20
TLH
Tallahassee Intl.
SUX
Sioux Gateway
$587 Roundtrip, found 18 hours ago
$587
Roundtrip
found 18 hours ago
Select United flight, departing Wed, May 14 from Tallahassee Intl. to Sioux Gateway, returning Tue, May 20, priced at $587 found 18 hours ago
Delta
Fri, May 9 - Tue, May 13
CLT
Charlotte-Douglas Intl.
FSD
Sioux Falls Regional
$693 Roundtrip, found 4 hours ago
$693
Roundtrip
found 4 hours ago
Select Delta flight, departing Fri, May 9 from Charlotte-Douglas Intl. to Sioux Falls Regional, returning Tue, May 13, priced at $693 found 4 hours ago

Cheap Flights to Irene

Fall in love at first flight with your vacation to Irene by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Irene on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Irene, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Irene

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Irene with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the YKN airport.

What is the cheapest month to fly to Irene?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Irene are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Irene?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Irene.

What airport is best to fly into Irene?

When you’re planning your trip to Irene, convenience is the name of the game. Luckily, Irene Sioux Falls Regional Airport is nearby so you can deplane and get going on checking off everything on your Irene must-do list.

How much are flights to Irene?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Irene on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $242, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Irene?

The trick to saving a stack of cash on your flight to Irene? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $242 right now, why wait?

Irene Flight Information
Destination airport
Sioux Falls Regional
Destination airport IATA code
FSD
Roundtrip price
$352

Last Minute Hotel Deals in Irene

Best Western Kelly Inn
Best Western Kelly Inn
2.5 out of 5
1607 E Highway 50, Yankton, SD
The price is $117 per night from May 18 to May 19
$117
includes taxes & fees
May 18 - May 19
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (571 reviews)
"Clean and safe. Great place"

Reviewed on May 2, 2025

Best Western Kelly Inn
Fairfield Inn & Suites by Marriott Yankton
Fairfield Inn & Suites by Marriott Yankton
2.5 out of 5
508 WEST 21ST STREET, Yankton, SD
The price is $148 per night from May 25 to May 26
$148
includes taxes & fees
May 25 - May 26
Stay at this hotel in Yankton. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (120 reviews)
"The hotel is nice and clean. The breakfast was a typical hotel breakfast; however, the gal working the dining area was phenomenal! She was better and more attentive than most waitresses working for a tip! I wish I caught her name, but WOW She was such a delight! The only reason I give 4 stars is ..."

Reviewed on Apr 29, 2025

Fairfield Inn & Suites by Marriott Yankton
Comfort Inn Yankton SD
Comfort Inn Yankton SD
2.5 out of 5
611 W 23rd Street, Yankton, SD
The price is $122 per night from May 26 to May 27
$122
includes taxes & fees
May 26 - May 27
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (581 reviews)
Comfort Inn Yankton
"Clean throughout. Breakfast was free. Whirlpool worked and was hot as advertised. Beds are soft. Nice hotel for the price."

Reviewed on Apr 28, 2025

Comfort Inn Yankton SD
Lewis and Clark Resort
Lewis and Clark Resort
2.5 out of 5
43496 Shore Drive, Yankton, SD
The price is $122 per night from May 7 to May 8
$122
includes taxes & fees
May 7 - May 8
Book a stay at this beach hotel in Yankton. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Lewis and Clark Recreation Area and Midway ...
8.6/10 Excellent! (209 reviews)
Would recommend
"Great facilities- affordable and clean. We were very happy with our stay."

Reviewed on May 4, 2025

Lewis and Clark Resort
Yankton Inn
Yankton Inn
2 out of 5
1603 East Highway 50, Yankton, SD
The price is $94 per night from May 7 to May 8
$94
includes taxes & fees
May 7 - May 8
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (198 reviews)
"A non-chain family run location, we took a flyer and discovered this little gem. Price point is great. As travelling snowbirds this location was convenient to our route. Check in was quick and easy. Sam was pleasant and helpful. You can tell they work hard and are slowly upgrading this facility. ..."

Reviewed on Apr 8, 2025

Yankton Inn
Econo Lodge Inn & Suites
Econo Lodge Inn & Suites
2 out of 5
2410 Broadway Ave, Yankton, SD
The price is $96 per night from May 12 to May 13
$96
includes taxes & fees
May 12 - May 13
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fox Run Plaza and Augusta Park ...
7.2/10 Good! (637 reviews)
"Good area of town"

Reviewed on Apr 27, 2025

Econo Lodge Inn & Suites
Holiday Inn Express & Suites Yankton by IHG
Holiday Inn Express & Suites Yankton by IHG
2.5 out of 5
2607 Broadway Ave, Yankton, SD
The price is $131 per night from May 11 to May 12
$131
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (388 reviews)
"Staff was great! So helpful and friendly. Hot breakfast was so nice and complimentary welcome happy hour was a a nice surprise. I would stay again! Oh, and beds and pillows were really comfortable."

Reviewed on Apr 10, 2025

Holiday Inn Express & Suites Yankton by IHG
Super 8 by Wyndham Beresford
Super 8 by Wyndham Beresford
2 out of 5
1410 W Cedar St, Hwy 46 & I-29, Beresford, SD
The price is $59 per night from May 26 to May 27
$59
includes taxes & fees
May 26 - May 27
Book a stay at this business-friendly motel in Beresford. Enjoy free breakfast, free WiFi, and free parking.
6.2/10 (251 reviews)
"Our truck broke down on the freeway and was towed to Beresford. We asked if we could check in early and the manager said we could. We were able to check in at 12:30pm for a VERY small fee. This was extremely helpful as my husband had just had surgery and needed to rest. The staff was extremely helpful- ..."

Reviewed on Mar 14, 2025

Super 8 by Wyndham Beresford
See all 79 properties in Irene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.