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Irene

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Irene Flights as Low as $226

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Fri, May 2 - Mon, May 5
PHX
Sky Harbor Intl.
FSD
Sioux Falls Regional
$226 Roundtrip, found 1 day ago
$226
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, May 2 from Sky Harbor Intl. to Sioux Falls Regional, returning Mon, May 5, priced at $226 found 1 day ago
Frontier Airlines
Mon, Apr 28 - Fri, May 2
PHX
Sky Harbor Intl.
FSD
Sioux Falls Regional
$231 Roundtrip, found 6 hours ago
$231
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Mon, Apr 28 from Sky Harbor Intl. to Sioux Falls Regional, returning Fri, May 2, priced at $231 found 6 hours ago
Frontier Airlines
Fri, Apr 25 - Fri, May 2
PHX
Sky Harbor Intl.
FSD
Sioux Falls Regional
$232 Roundtrip, found 6 hours ago
$232
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Fri, Apr 25 from Sky Harbor Intl. to Sioux Falls Regional, returning Fri, May 2, priced at $232 found 6 hours ago
American Airlines
Thu, May 1 - Tue, May 6
PHX
Sky Harbor Intl.
FSD
Sioux Falls Regional
$261 Roundtrip, found 1 day ago
$261
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, May 1 from Sky Harbor Intl. to Sioux Falls Regional, returning Tue, May 6, priced at $261 found 1 day ago
American Airlines
Wed, May 7 - Sat, May 17
OKC
Will Rogers World
FSD
Sioux Falls Regional
$269 Roundtrip, found 1 day ago
$269
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 7 from Will Rogers World to Sioux Falls Regional, returning Sat, May 17, priced at $269 found 1 day ago
American Airlines
Tue, May 6 - Sat, May 17
OKC
Will Rogers World
FSD
Sioux Falls Regional
$271 Roundtrip, found 1 day ago
$271
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, May 6 from Will Rogers World to Sioux Falls Regional, returning Sat, May 17, priced at $271 found 1 day ago
Frontier Airlines
Sun, May 4 - Fri, May 16
OKC
Will Rogers World
FSD
Sioux Falls Regional
$271 Roundtrip, found 1 day ago
$271
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, May 4 from Will Rogers World to Sioux Falls Regional, returning Fri, May 16, priced at $271 found 1 day ago
Frontier Airlines
Thu, May 8 - Fri, May 16
OKC
Will Rogers World
FSD
Sioux Falls Regional
$273 Roundtrip, found 1 day ago
$273
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, May 8 from Will Rogers World to Sioux Falls Regional, returning Fri, May 16, priced at $273 found 1 day ago
American Airlines
Sat, May 3 - Sat, May 17
OKC
Will Rogers World
FSD
Sioux Falls Regional
$275 Roundtrip, found 1 day ago
$275
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, May 3 from Will Rogers World to Sioux Falls Regional, returning Sat, May 17, priced at $275 found 1 day ago
Delta
Wed, Apr 23 - Tue, Apr 29
PHX
Sky Harbor Intl.
FSD
Sioux Falls Regional
$279 Roundtrip, found 6 hours ago
$279
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, Apr 23 from Sky Harbor Intl. to Sioux Falls Regional, returning Tue, Apr 29, priced at $279 found 6 hours ago
Delta
Fri, May 2 - Wed, May 7
PHX
Sky Harbor Intl.
FSD
Sioux Falls Regional
$280 Roundtrip, found 1 day ago
$280
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, May 2 from Sky Harbor Intl. to Sioux Falls Regional, returning Wed, May 7, priced at $280 found 1 day ago
Delta
Thu, Apr 24 - Tue, Apr 29
PHX
Sky Harbor Intl.
FSD
Sioux Falls Regional
$281 Roundtrip, found 6 hours ago
$281
Roundtrip
found 6 hours ago
Select Delta flight, departing Thu, Apr 24 from Sky Harbor Intl. to Sioux Falls Regional, returning Tue, Apr 29, priced at $281 found 6 hours ago
American Airlines
Wed, May 7 - Fri, May 16
OKC
Will Rogers World
FSD
Sioux Falls Regional
$294 Roundtrip, found 1 day ago
$294
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 7 from Will Rogers World to Sioux Falls Regional, returning Fri, May 16, priced at $294 found 1 day ago
American Airlines
Tue, May 6 - Fri, May 16
OKC
Will Rogers World
FSD
Sioux Falls Regional
$296 Roundtrip, found 1 day ago
$296
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, May 6 from Will Rogers World to Sioux Falls Regional, returning Fri, May 16, priced at $296 found 1 day ago
American Airlines
Sat, May 3 - Fri, May 16
OKC
Will Rogers World
FSD
Sioux Falls Regional
$300 Roundtrip, found 1 day ago
$300
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, May 3 from Will Rogers World to Sioux Falls Regional, returning Fri, May 16, priced at $300 found 1 day ago
United
Thu, May 1 - Tue, May 6
PHX
Sky Harbor Intl.
FSD
Sioux Falls Regional
$377 Roundtrip, found 1 day ago
$377
Roundtrip
found 1 day ago
Select United flight, departing Thu, May 1 from Sky Harbor Intl. to Sioux Falls Regional, returning Tue, May 6, priced at $377 found 1 day ago

Cheap Flights to Irene

Fall in love at first flight with your vacation to Irene by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Irene on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Irene, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Irene

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Irene with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the YKN airport.

What is the cheapest month to fly to Irene?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Irene are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Irene?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Irene.

What airport is best to fly into Irene?

When you’re planning your trip to Irene, convenience is the name of the game. Luckily, Irene Sioux Falls Regional Airport is nearby so you can deplane and get going on checking off everything on your Irene must-do list.

How much are flights to Irene?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Irene on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $226, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Irene?

The trick to saving a stack of cash on your flight to Irene? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $226 right now, why wait?

Irene Flight Information
Destination airport
Sioux Falls Regional
Destination airport IATA code
FSD
Roundtrip price
$226

Last Minute Hotel Deals in Irene

Fairfield Inn & Suites by Marriott Yankton
Fairfield Inn & Suites by Marriott Yankton
2.5 out of 5
508 WEST 21ST STREET, Yankton, SD
The price is $148 per night from Mar 16 to Mar 17
$148
includes taxes & fees
Mar 16 - Mar 17
Stay at this hotel in Yankton. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (112 reviews)
"Good"

Reviewed on Mar 7, 2025

Fairfield Inn & Suites by Marriott Yankton
Holiday Inn Express & Suites Yankton by IHG
Holiday Inn Express & Suites Yankton by IHG
2.5 out of 5
2607 Broadway Ave, Yankton, SD
The price is $150 per night from Mar 23 to Mar 24
$150
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (385 reviews)
"I loved my experience here. The staff was wonderful and so was the breakfast. It’s definitely family friendly which as a solo traveller made me feel safer. I’ll be back!"

Reviewed on Mar 11, 2025

Holiday Inn Express & Suites Yankton by IHG
Comfort Inn Yankton SD
Comfort Inn Yankton SD
2.5 out of 5
611 W 23rd Street, Yankton, SD
The price is $107 per night from Mar 27 to Mar 28
$107
includes taxes & fees
Mar 27 - Mar 28
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (569 reviews)
"Just an average motel but kept well and was decent."

Reviewed on Feb 24, 2025

Comfort Inn Yankton SD
Best Western Kelly Inn
Best Western Kelly Inn
2.5 out of 5
1607 E Highway 50, Yankton, SD
The price is $120 per night from Mar 20 to Mar 21
$120
includes taxes & fees
Mar 20 - Mar 21
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (559 reviews)
"Very clean with a great selection each morning for breakfast"

Reviewed on Mar 9, 2025

Best Western Kelly Inn
Lewis and Clark Resort
Lewis and Clark Resort
2.5 out of 5
43496 Shore Drive, Yankton, SD
The price is $116 per night from Mar 16 to Mar 17
$116
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this beach hotel in Yankton. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Lewis and Clark Recreation Area and Midway ...
8.6/10 Excellent! (199 reviews)
"There was NO staff! I literally pulled my envelope from the wall with my last name on it. Went to turn in my key and the same thing. Just a drop box. Then they wanted me to pay for car parking. Which was just another envelope process outside. It was easy and efficient just wanted to clarify there ..."

Reviewed on Mar 4, 2025

Lewis and Clark Resort
Econo Lodge Inn & Suites
Econo Lodge Inn & Suites
2 out of 5
2410 Broadway Ave, Yankton, SD
The price is $81 per night from Mar 23 to Mar 24
$81
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fox Run Plaza and Augusta Park ...
7.2/10 Good! (630 reviews)
"Met my needs"

Reviewed on Feb 26, 2025

Econo Lodge Inn & Suites
Yankton Inn
Yankton Inn
2 out of 5
1603 East Highway 50, Yankton, SD
The price is $87 per night from Mar 27 to Mar 28
$87
includes taxes & fees
Mar 27 - Mar 28
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (192 reviews)
"It was easy to find. I liked the well lighted outside at night. It was very quiet."

Reviewed on Jan 7, 2025

Yankton Inn
Super 8 by Wyndham Beresford
Super 8 by Wyndham Beresford
2 out of 5
1410 W Cedar St, Hwy 46 & I-29, Beresford, SD
The price is $58 per night from Mar 19 to Mar 20
$58
includes taxes & fees
Mar 19 - Mar 20
Book a stay at this business-friendly motel in Beresford. Enjoy free breakfast, free WiFi, and free parking.
6.2/10 (249 reviews)
"Our truck broke down on the freeway and was towed to Beresford. We asked if we could check in early and the manager said we could. We were able to check in at 12:30pm for a VERY small fee. This was extremely helpful as my husband had just had surgery and needed to rest. The staff was extremely helpful- ..."

Reviewed on Mar 14, 2025

Super 8 by Wyndham Beresford
See all 80 properties in Irene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.