Search for Cheap Deals on
Hotels in Irene

Choose from 80 Irene Hotel Deals

Fairfield Inn & Suites by Marriott Yankton
Fairfield Inn & Suites by Marriott Yankton
2.5 out of 5
508 WEST 21ST STREET, Yankton, SD
  • 9 hours drive from Missouri River
The price is $148 per night from Mar 16 to Mar 17
$148
includes taxes & fees
Mar 16 - Mar 17
Stay at this hotel in Yankton. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (112 reviews)
"Good"

Reviewed on Mar 7, 2025

Fairfield Inn & Suites by Marriott Yankton
Holiday Inn Express & Suites Yankton by IHG
Holiday Inn Express & Suites Yankton by IHG
2.5 out of 5
2607 Broadway Ave, Yankton, SD
  • 9 hours drive from Missouri River
The price is $135 per night from Mar 15 to Mar 16
$135
includes taxes & fees
Mar 15 - Mar 16
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (385 reviews)
"I loved my experience here. The staff was wonderful and so was the breakfast. It’s definitely family friendly which as a solo traveller made me feel safer. I’ll be back!"

Reviewed on Mar 11, 2025

Holiday Inn Express & Suites Yankton by IHG
Comfort Inn Yankton SD
Comfort Inn Yankton SD
2.5 out of 5
611 W 23rd Street, Yankton, SD
  • 9 hours drive from Missouri River
The price is $107 per night from Mar 26 to Mar 27
$107
includes taxes & fees
Mar 26 - Mar 27
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (569 reviews)
"Just an average motel but kept well and was decent."

Reviewed on Feb 24, 2025

Comfort Inn Yankton SD
Best Western Kelly Inn
Best Western Kelly Inn
2.5 out of 5
1607 E Highway 50, Yankton, SD
  • 9 hours drive from Missouri River
The price is $120 per night from Mar 16 to Mar 17
$120
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (559 reviews)
"Very clean with a great selection each morning for breakfast"

Reviewed on Mar 9, 2025

Best Western Kelly Inn
Lewis and Clark Resort
Lewis and Clark Resort
2.5 out of 5
43496 Shore Drive, Yankton, SD
  • 9 hours drive from Missouri River
The price is $116 per night from Mar 16 to Mar 17
$116
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this beach hotel in Yankton. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Lewis and Clark Recreation Area and Midway ...
8.6/10 Excellent! (199 reviews)
"There was NO staff! I literally pulled my envelope from the wall with my last name on it. Went to turn in my key and the same thing. Just a drop box. Then they wanted me to pay for car parking. Which was just another envelope process outside. It was easy and efficient just wanted to clarify there ..."

Reviewed on Mar 4, 2025

Lewis and Clark Resort
Econo Lodge Inn & Suites
Econo Lodge Inn & Suites
2 out of 5
2410 Broadway Ave, Yankton, SD
  • 9 hours drive from Missouri River
The price is $81 per night from Mar 19 to Mar 20
$81
includes taxes & fees
Mar 19 - Mar 20
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fox Run Plaza and Augusta Park ...
7.2/10 Good! (629 reviews)
"Met my needs"

Reviewed on Feb 26, 2025

Econo Lodge Inn & Suites
Yankton Inn
Yankton Inn
2 out of 5
1603 East Highway 50, Yankton, SD
  • 9 hours drive from Missouri River
The price is $87 per night from Mar 16 to Mar 17
$87
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (192 reviews)
"It was easy to find. I liked the well lighted outside at night. It was very quiet."

Reviewed on Jan 7, 2025

Yankton Inn
Super 8 by Wyndham Beresford
Super 8 by Wyndham Beresford
2 out of 5
1410 W Cedar St, Hwy 46 & I-29, Beresford, SD
  • 6 hours drive from Missouri River
The price is $58 per night from Mar 19 to Mar 20
$58
includes taxes & fees
Mar 19 - Mar 20
Book a stay at this business-friendly motel in Beresford. Enjoy free breakfast, free WiFi, and free parking.
6.2/10 (248 reviews)
"Just passing through and decided to stay the night. Reviews are dark and negative. You get whatcha pd for. Unfortunately the pool is OOO however we weren't needed the pool this journey. Room is spacious, clean. They could leave hygiene items in room for use yet WE plan for the just in case and bring ..."

Reviewed on Oct 30, 2024

Super 8 by Wyndham Beresford
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Irene

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Irene hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Irene.

Choosing the right hotel in South Dakota has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Irene’s 80 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $58. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Irene hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Irene. No matter your reason for visiting Irene, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Irene hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Irene for as low as $58.

How many hotels are there in Irene?

With over 80 hotels in Irene, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $58.

How to find cheap car rentals in Irene?

Finding a cheap car rental deal in Irene is as easy as scoring cheap hotels in Irene. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.