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Hotels in Vermillion

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Choose from 225 Vermillion Hotel Deals

Best Western Vermillion Inn

Best Western Vermillion Inn

2.5 out of 5
701 W Cherry St Vermillion SD
  • 10 min walk from University of South Dakota
Stay at this hotel in Vermillion. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (600 reviews)
"First time in Vermillion. Decided to go there and avoid outrageous room costs in Sioux Falls. I will go again. This was easy to get to and was a nice place."

Reviewed on Jun 15, 2026

Best Western Vermillion Inn
Red Roof Inn Vermillion - U of South Dakota

Red Roof Inn Vermillion - U of South Dakota

2 out of 5
1208 E Cherry St Vermillion SD
  • 5 min walk from University of South Dakota
Stay at this hotel in Vermillion. Enjoy free breakfast, free WiFi, and free parking. Popular attractions W. H. Over Museum and National Music Museum are located ...
Red Roof Inn Vermillion - U of South Dakota
Prairie Inn

Prairie Inn

2 out of 5
916 N Dakota Street Vermillion SD
  • 7 min walk from University of South Dakota
Stay at this hotel in Vermillion. Enjoy free WiFi, free parking, and room service. Popular attractions DakotaDome and Sanford Coyote Sports Center are located ...
7.2/10 Good! (347 reviews)
"The front desk attendant at check-in was friendly and helpful. Walls are a little thin so it was a bit noisy until 11pm and at 6 am. The shower wouldn't work and the temperature was only boiling hot. The adjuster just spun and the shower stopped wouldn't stay up. When I told the lady at the front ..."

Reviewed on Jun 19, 2026

Prairie Inn
Holiday Inn Express Hotel & Suites Vermillion by IHG

Holiday Inn Express Hotel & Suites Vermillion by IHG

2.5 out of 5
1200 N Dakota St Vermillion SD
  • 9 min walk from University of South Dakota
Stay at this hotel in Vermillion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.2/10 Very Good! (423 reviews)
"Convenient location"

Reviewed on Jun 24, 2026

Holiday Inn Express Hotel & Suites Vermillion by IHG
Stoney Creek Hotel Sioux City

Stoney Creek Hotel Sioux City

2.5 out of 5
300 3rd Street Sioux City IA
  • 52 min drive from University of South Dakota
Book a stay at this business-friendly hotel in Sioux City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
9/10 Wonderful! (2,406 reviews)
"Room was clean. Breakfast was adequate. Would stay again."

Reviewed on Jun 27, 2026

Stoney Creek Hotel Sioux City
Hard Rock Hotel & Casino Sioux City

Hard Rock Hotel & Casino Sioux City

4 out of 5
111 3rd Street Sioux City IA
  • 51 min drive from University of South Dakota
Book a stay at this business-friendly hotel in Sioux City. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,008 reviews)
"The room was great. I would stay there again. I wish there was no smoking in the casino. But the room in our hotel did not smell."

Reviewed on Jun 25, 2026

Hard Rock Hotel & Casino Sioux City
New Victorian Inn & Suites in Sioux City, IA

New Victorian Inn & Suites in Sioux City, IA

2.5 out of 5
3101 Singing Hills Blvd Sioux City IA
  • 59 min drive from University of South Dakota
Book a stay at this business-friendly hotel in Sioux City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,003 reviews)
"Their breakfast and room is excellent. I highly recommend it"

Reviewed on Jun 27, 2026

New Victorian Inn & Suites in Sioux City, IA
The Warrior Hotel, Autograph Collection

The Warrior Hotel, Autograph Collection

5 out of 5
525 6TH STREET Sioux City IA
  • 51 min drive from University of South Dakota
Book a stay at this luxury hotel in Sioux City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
9/10 Wonderful! (627 reviews)
"over hyped but was really nice in the inside you also don’t have a microwave in your room"

Reviewed on Jun 27, 2026

The Warrior Hotel, Autograph Collection
Courtyard by Marriott Sioux City Downtown/Convention Center

Courtyard by Marriott Sioux City Downtown/Convention Center

3 out of 5
901 4th Street Sioux City IA
  • 51 min drive from University of South Dakota
Stay at this hotel in Sioux City. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.2/10 Wonderful! (690 reviews)
"Clean property and perfectly located in downtown Sioux City. For it to be downtown, parking was easy and efficient. I’d recommend this property for travelers."

Reviewed on Jun 23, 2026

Courtyard by Marriott Sioux City Downtown/Convention Center
Wingate by Wyndham Sioux City

Wingate by Wyndham Sioux City

3 out of 5
4716 Southern Hills Drive Sioux City IA
  • 59 min drive from University of South Dakota
Book a stay at this business-friendly hotel in Sioux City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (826 reviews)
"Room its not clean. There was alot of dirt on the floor."

Reviewed on Jun 27, 2026

Wingate by Wyndham Sioux City
Cottonwood Inn and Conference Center

Cottonwood Inn and Conference Center

2.5 out of 5
4402 Dakota Ave South Sioux City NE
  • 58 min drive from University of South Dakota
Stay at this hotel in South Sioux City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,000 reviews)
"Great value, each door has a vinyl graphic on it, which is fun and unusual. Good continental breakfast, waffle maker was wonderful"

Reviewed on Jun 18, 2026

Cottonwood Inn and Conference Center
Comfort Inn Sioux City South

Comfort Inn Sioux City South

2.5 out of 5
4202 S Lakeport St Sioux City IA
  • 59 min drive from University of South Dakota
Stay at this hotel in Sioux City. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (659 reviews)
"The Sioux City Comfort Inn was substandard at best. First thing I noticed as I checked in was a sign on the desk saying they don't allow locals to stay there because of past "problems"; clue #1 as to how the night would go. Next thing I noticed was the side door we used to bring our stuff in had ..."

Reviewed on Jun 22, 2026

Comfort Inn Sioux City South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Vermillion

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Vermillion.

Choosing the right hotel in South Dakota has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Vermillion’s 225 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $78. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Vermillion hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Vermillion. No matter your reason for visiting Vermillion, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Vermillion hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Vermillion for as low as $78.

How many hotels are there in Vermillion?

With over 225 hotels in Vermillion, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $78.

How to find cheap car rentals in Vermillion?

Finding a cheap car rental deal in Vermillion is as easy as scoring cheap hotels in Vermillion. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.