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Isla Santa María

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Isla Santa María Flights as Low as $310

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
avianca
United

Cheap Flights to Isla Santa María

Fall in love at first flight with your vacation to Isla Santa María by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Isla Santa María on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Isla Santa María, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Isla Santa María

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Isla Santa María with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GPS airport.

What is the cheapest month to fly to Isla Santa María?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Isla Santa María are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Isla Santa María?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Isla Santa María.

What airport is best to fly into Isla Santa María?

When you’re planning your trip to Isla Santa María, convenience is the name of the game. Luckily, Isla Santa María José de Villamil Airport Airport is nearby so you can deplane and get going on checking off everything on your Isla Santa María must-do list.

How much are flights to Isla Santa María?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Isla Santa María on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $310, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Isla Santa María?

The trick to saving a stack of cash on your flight to Isla Santa María? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $310 right now, why wait?

Isla Santa María Flight Information
Destination airport
Seymour
Destination airport IATA code
GPS
Roundtrip price
$310

Last Minute Hotel Deals in Isla Santa María

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo, Puerto Ayora, Galapagos
Stay at this 3.5-star hotel in Puerto Ayora. Enjoy free WiFi, 3 hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (351 reviews)
Helpful Staff and Great Location
"The staff was very helpful and the hotel was in a safe and quiet location. The pool was cold but nice and the pillows were some of the most comfortable I’ve ever slept on."

Reviewed on Jul 25, 2025

Hotel Fiesta
El Barranco Galapagos

El Barranco Galapagos

2.5 out of 5
Los colonos, Puerto Ayora, Galapagos
Stay at this hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and room service. Popular attractions Malecon and Gus Angermeyer Ferry Terminal are located ...
9.2/10 Wonderful! (10 reviews)
"amazing hotel and the best service the pool is the perfect spot to see seals, sea turtles, sting rays, sharks and pelicans , at night it’s quiet and the room was perfect. loved especially my balcony overlooking the docks."

Reviewed on Jul 6, 2025

El Barranco Galapagos
Ikala Galapagos Hotel

Ikala Galapagos Hotel

4 out of 5
Tomas de Berlanga 110 y Moises Brito, Puerto Ayora, Ecuador
Stay at this 4-star business-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff and ...
9.6/10 Exceptional! (114 reviews)
"Beds too hard"

Reviewed on May 28, 2025

Ikala Galapagos Hotel
Hotel Cucuve

Hotel Cucuve

4 out of 5
Charles Binford 083 y Ave Charles Darwin, Puerto Ayora
Stay at this 4-star B&B in Puerto Ayora. Enjoy free breakfast, free WiFi, and an airport shuttle (surcharge). Our guests praise the breakfast and the helpful ...
9.8/10 Exceptional! (255 reviews)
"Excellent"

Reviewed on Jul 22, 2025

Hotel Cucuve
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador, Puerto Ayora, Galapagos
Stay at this 3.5-star family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our ...
8.6/10 Excellent! (159 reviews)
"I only leave a 4 star review because I stayed for 5 days and the breakfasts were boring. Every day they offered the same thing, eggs, toast, or pancakes, cereal and strawberry yogurt. They don’t have a restaurant in the hotel and everything is far away. After the second day I was bored with the breakfast ..."

Reviewed on Jun 29, 2025

Hotel el descanso del Guia
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

4.5 out of 5
Barrio Punta Estrada, Puerto Ayora, Galapagos
Stay at this 4.5-star luxury hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Playa de los Alemanes and Malecon ...
9.2/10 Wonderful! (86 reviews)
"Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!"

Reviewed on Dec 31, 2024

Finch Bay Galapagos Hotel
Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge

4 out of 5
Ave. Charles Darwin S/n Y Piquero, Puerto Ayora, Galapagos
Stay at this 4-star business-friendly hotel in Puerto Ayora. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in ...
8.8/10 Excellent! (113 reviews)
"Wonderful hotel. Our room was incredible. We stayed in Darwin. But there was no hot water for 2/3 of our stay. All we were able to get out of them was a free breakfast one day. I would have expected a significant discount given this lacking amenity"

Reviewed on May 27, 2025

Blu Galapagos Sustainable Waterfront Lodge
Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

3.5 out of 5
Punta Estrada, Isla Santa Cruz, Puerto Ayora, Galapagos
Stay at this 3.5-star hotel in Puerto Ayora. Enjoy free WiFi, a marina, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (118 reviews)
"Staff was very friendly and professional. They helped us with everything we asked for."

Reviewed on Jul 4, 2025

Angermeyer Waterfront Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.