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Isla Santa María

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Isla Santa María Flights as Low as $282

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

LATAM Airlines Group
Tue, Jul 29 - Wed, Aug 6
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$282 Roundtrip, found 6 days ago
$282
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Tue, Jul 29 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Wed, Aug 6, priced at $282 found 6 days ago
LATAM Airlines Group
Wed, Jul 30 - Wed, Aug 6
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$286 Roundtrip, found 6 days ago
$286
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Wed, Jul 30 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Wed, Aug 6, priced at $286 found 6 days ago
LATAM Airlines Group
Tue, Jul 29 - Tue, Aug 5
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$293 Roundtrip, found 6 days ago
$293
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Tue, Jul 29 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Tue, Aug 5, priced at $293 found 6 days ago
LATAM Airlines Group
Wed, Jul 30 - Tue, Aug 5
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$298 Roundtrip, found 6 days ago
$298
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Wed, Jul 30 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Tue, Aug 5, priced at $298 found 6 days ago
LATAM Airlines Group
Fri, Aug 1 - Wed, Aug 6
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$303 Roundtrip, found 6 days ago
$303
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Fri, Aug 1 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Wed, Aug 6, priced at $303 found 6 days ago
LATAM Airlines Group
Sat, Aug 2 - Tue, Aug 5
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$309 Roundtrip, found 6 days ago
$309
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Sat, Aug 2 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Tue, Aug 5, priced at $309 found 6 days ago
LATAM Airlines Group
Tue, Jul 29 - Thu, Aug 7
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$315 Roundtrip, found 6 days ago
$315
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Tue, Jul 29 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Thu, Aug 7, priced at $315 found 6 days ago
LATAM Airlines Group
Wed, Jul 30 - Thu, Aug 7
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$320 Roundtrip, found 6 days ago
$320
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Wed, Jul 30 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Thu, Aug 7, priced at $320 found 6 days ago
LATAM Airlines Group
Sat, Aug 2 - Thu, Aug 7
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$332 Roundtrip, found 6 days ago
$332
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Sat, Aug 2 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Thu, Aug 7, priced at $332 found 6 days ago
LATAM Airlines Group
Fri, Aug 1 - Thu, Aug 7
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$337 Roundtrip, found 6 days ago
$337
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Fri, Aug 1 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Thu, Aug 7, priced at $337 found 6 days ago
LATAM Airlines Group
Sat, Aug 2 - Fri, Aug 8
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$342 Roundtrip, found 6 days ago
$342
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Sat, Aug 2 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Fri, Aug 8, priced at $342 found 6 days ago
LATAM Airlines Group
Sat, Aug 2 - Fri, Aug 8
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$354 Roundtrip, found 6 days ago
$354
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Sat, Aug 2 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Fri, Aug 8, priced at $354 found 6 days ago
LATAM Airlines Group
Mon, Jul 14 - Thu, Jul 17
GYE
Jose Joaquin de Olmedo Intl.
GPS
Seymour
$356 Roundtrip, found 1 day ago
$356
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Mon, Jul 14 from Jose Joaquin de Olmedo Intl. to Seymour, returning Thu, Jul 17, priced at $356 found 1 day ago
avianca
Tue, Aug 5 - Thu, Aug 7
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$399 Roundtrip, found 6 days ago
$399
Roundtrip
found 6 days ago
Select avianca flight, departing Tue, Aug 5 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Thu, Aug 7, priced at $399 found 6 days ago
LATAM Airlines Group
Sat, Jul 5 - Mon, Jul 14
LIM
Jorge Chávez Intl.
GPS
Seymour
$808 Roundtrip, found 4 days ago
$808
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Sat, Jul 5 from Jorge Chávez Intl. to Seymour, returning Mon, Jul 14, priced at $808 found 4 days ago
Iberia
Fri, Apr 10 - Mon, Apr 13
ZRH
Zürich
GPS
Seymour
$2,195 Roundtrip, found 7 hours ago
$2,195
Roundtrip
found 7 hours ago
Select Iberia flight, departing Fri, Apr 10 from Zürich to Seymour, returning Mon, Apr 13, priced at $2,195 found 7 hours ago

Cheap Flights to Isla Santa María

Fall in love at first flight with your vacation to Isla Santa María by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Isla Santa María on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Isla Santa María, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Isla Santa María

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Isla Santa María with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GPS airport.

What is the cheapest month to fly to Isla Santa María?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Isla Santa María are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Isla Santa María?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Isla Santa María.

What airport is best to fly into Isla Santa María?

When you’re planning your trip to Isla Santa María, convenience is the name of the game. Luckily, Isla Santa María José de Villamil Airport Airport is nearby so you can deplane and get going on checking off everything on your Isla Santa María must-do list.

How much are flights to Isla Santa María?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Isla Santa María on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $282, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Isla Santa María?

The trick to saving a stack of cash on your flight to Isla Santa María? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $282 right now, why wait?

Isla Santa María Flight Information
Destination airport
San Cristobal
Destination airport IATA code
SCY
Roundtrip price
$281

Last Minute Hotel Deals in Isla Santa María

Hotel Fiesta
Hotel Fiesta
3.5 out of 5
Calle Moises Brito y Juan Montalvo, Puerto Ayora, Galapagos
Stay at this 3.5-star hotel in Puerto Ayora. Enjoy free WiFi, 3 hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (338 reviews)
"Great staff, pool, and room."

Reviewed on Jun 30, 2025

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Hotel Fiesta
El Barranco Galapagos
El Barranco Galapagos
3 out of 5
Los colonos, Puerto Ayora, Galapagos
Stay at this 3-star hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and room service. Popular attractions Malecon and Gus Angermeyer Ferry Terminal are ...
9.4/10 Exceptional! (6 reviews)
"Amazing location overlooking the bay. We saw sea turtles, reef sharks, sea lions and lots of fish just sitting at the bar sipping cocktails. Breakfast is at the sister hotel across the road. The food served is from 2pm-10pm only (and also comes from across the street) and is cash only but very delicious ..."

Reviewed on Jun 10, 2025

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El Barranco Galapagos
Hotel el descanso del Guia
Hotel el descanso del Guia
3.5 out of 5
Calle Delfin, Barrio el Mirador, Puerto Ayora, Galapagos
Stay at this 3.5-star family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (156 reviews)
"I only leave a 4 star review because I stayed for 5 days and the breakfasts were boring. Every day they offered the same thing, eggs, toast, or pancakes, cereal and strawberry yogurt. They don’t have a restaurant in the hotel and everything is far away. After the second day I was bored with the breakfast ..."

Reviewed on Jun 29, 2025

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Hotel el descanso del Guia
Finch Bay Galapagos Hotel
Finch Bay Galapagos Hotel
4.5 out of 5
Barrio Punta Estrada, Puerto Ayora, Galapagos
Stay at this 4.5-star luxury hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Playa de los Alemanes and Malecon ...
9.2/10 Wonderful! (85 reviews)
"Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!"

Reviewed on Dec 31, 2024

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Finch Bay Galapagos Hotel
Angermeyer Waterfront Inn
Angermeyer Waterfront Inn
3.5 out of 5
Punta Estrada, Isla Santa Cruz, Puerto Ayora, Galapagos
Stay at this 3.5-star hotel in Puerto Ayora. Enjoy free WiFi, a marina, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (115 reviews)
"Excellent - great ambiance with waterfront and bungalow rooms and foliage on the ground . Very accommodating and friendly staff and water taxi was convenient to have an oasis within reach of the town"

Reviewed on May 30, 2025

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Angermeyer Waterfront Inn
Ikala Galapagos Hotel
Ikala Galapagos Hotel
4 out of 5
Tomas de Berlanga 110 y Moises Brito, Puerto Ayora, Ecuador
Stay at this 4-star business-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff and ...
9.6/10 Exceptional! (110 reviews)
"Beds too hard"

Reviewed on May 28, 2025

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Ikala Galapagos Hotel
Hotel Cucuve
Hotel Cucuve
4 out of 5
Charles Binford 083 y Ave Charles Darwin, Puerto Ayora
Stay at this 4-star B&B in Puerto Ayora. Enjoy free breakfast, free WiFi, and an airport shuttle (surcharge). Our guests praise the breakfast and the helpful ...
9.8/10 Exceptional! (252 reviews)
"Amazing hotel. Ana and the rest of the staff were very friendly and kind. I greatly appreciate their hospitality and the amenities of the hotel. Very clean and comfortable. Great location right near ocean and short walk from restaurants and nature viewing. Can’t wait to come back!"

Reviewed on Jun 17, 2025

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Hotel Cucuve
Hotel La Casa de Judy
Hotel La Casa de Judy
3 out of 5
Calle No. 10, Barrio del Eden Avenida y Escalecia, Puerto Ayora, Santa Cruz
Stay at this 3-star hotel in Puerto Ayora. Enjoy free breakfast, daily housekeeping, and a garden. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (153 reviews)
"Excelente estadía"

Reviewed on May 26, 2025

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Hotel La Casa de Judy
See all 196 properties in Isla Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.