Search Cheap Flights to
Middlesboro

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Middlesboro Flights as Low as $203

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Bargain Flight
Tue, Jul 22 - Wed, Jul 30
CMH
John Glenn Columbus Intl.
TYS
McGhee Tyson
$203 Roundtrip, found 4 hours ago
$203
Roundtrip
found 4 hours ago
Select Bargain Flight flight, departing Tue, Jul 22 from John Glenn Columbus Intl. to McGhee Tyson, returning Wed, Jul 30, priced at $203 found 4 hours ago
American Airlines
Fri, Jul 4 - Tue, Jul 15
OKC
Will Rogers World
TYS
McGhee Tyson
$224 Roundtrip, found 1 hour ago
$224
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Jul 4 from Will Rogers World to McGhee Tyson, returning Tue, Jul 15, priced at $224 found 1 hour ago
American Airlines
Wed, May 21 - Wed, May 28
HRL
Valley Intl.
TYS
McGhee Tyson
$225 Roundtrip, found 8 hours ago
$225
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, May 21 from Valley Intl. to McGhee Tyson, returning Wed, May 28, priced at $225 found 8 hours ago
Bargain Flight
Tue, May 6 - Sat, May 10
DTW
Detroit Metropolitan Wayne County
TYS
McGhee Tyson
$232 Roundtrip, found 4 hours ago
$232
Roundtrip
found 4 hours ago
Select Bargain Flight flight, departing Tue, May 6 from Detroit Metropolitan Wayne County to McGhee Tyson, returning Sat, May 10, priced at $232 found 4 hours ago
Frontier Airlines
Thu, Apr 17 - Sun, Apr 20
DFW
Dallas-Fort Worth Intl.
TYS
McGhee Tyson
$242 Roundtrip, found 3 days ago
$242
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Thu, Apr 17 from Dallas-Fort Worth Intl. to McGhee Tyson, returning Sun, Apr 20, priced at $242 found 3 days ago
Delta
Sat, Aug 16 - Tue, Aug 19
FSD
Sioux Falls Regional
TYS
McGhee Tyson
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Aug 16 from Sioux Falls Regional to McGhee Tyson, returning Tue, Aug 19, priced at $249 found 1 day ago
American Airlines
Wed, May 28 - Tue, Jun 3
JFK
John F. Kennedy Intl.
TYS
McGhee Tyson
$251 Roundtrip, found 4 hours ago
$251
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Wed, May 28 from John F. Kennedy Intl. to McGhee Tyson, returning Tue, Jun 3, priced at $251 found 4 hours ago
American Airlines
Wed, Aug 6 - Sat, Aug 9
SJC
Norman Y. Mineta San Jose Intl.
TYS
McGhee Tyson
$251 Roundtrip, just found
$251
Roundtrip
just found
Select American Airlines flight, departing Wed, Aug 6 from Norman Y. Mineta San Jose Intl. to McGhee Tyson, returning Sat, Aug 9, priced at $251 just found
Delta
Tue, Apr 22 - Tue, Apr 29
BWI
Baltimore Washington Intl. Thurgood Marshall
TYS
McGhee Tyson
$254 Roundtrip, found 5 hours ago
$254
Roundtrip
found 5 hours ago
Select Delta flight, departing Tue, Apr 22 from Baltimore Washington Intl. Thurgood Marshall to McGhee Tyson, returning Tue, Apr 29, priced at $254 found 5 hours ago
Frontier Airlines
Thu, Apr 17 - Sun, Apr 20
SFO
San Francisco Intl.
TYS
McGhee Tyson
$262 Roundtrip, found 5 days ago
$262
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Thu, Apr 17 from San Francisco Intl. to McGhee Tyson, returning Sun, Apr 20, priced at $262 found 5 days ago
American Airlines
Mon, May 12 - Sat, May 17
MSP
Minneapolis - St. Paul Intl.
TYS
McGhee Tyson
$302 Roundtrip, found 18 hours ago
$302
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Mon, May 12 from Minneapolis - St. Paul Intl. to McGhee Tyson, returning Sat, May 17, priced at $302 found 18 hours ago
Bargain Flight
Wed, Jul 9 - Sat, Jul 12
CLT
Charlotte-Douglas Intl.
TYS
McGhee Tyson
$310 Roundtrip, found 1 day ago
$310
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Wed, Jul 9 from Charlotte-Douglas Intl. to McGhee Tyson, returning Sat, Jul 12, priced at $310 found 1 day ago
Delta
Tue, Sep 23 - Tue, Sep 30
DAL
Love Field
TYS
McGhee Tyson
$357 Roundtrip, found 4 days ago
$357
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Sep 23 from Love Field to McGhee Tyson, returning Tue, Sep 30, priced at $357 found 4 days ago
Delta
Fri, Apr 18 - Sat, Apr 26
GSO
Piedmont Triad Intl.
TYS
McGhee Tyson
$389 Roundtrip, found 1 day ago
$389
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Apr 18 from Piedmont Triad Intl. to McGhee Tyson, returning Sat, Apr 26, priced at $389 found 1 day ago
American Airlines
Fri, Jul 25 - Fri, Jul 25
FLL
Fort Lauderdale - Hollywood Intl.
TYS
McGhee Tyson
$439 Roundtrip, found 1 day ago
$439
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Jul 25 from Fort Lauderdale - Hollywood Intl. to McGhee Tyson, returning Fri, Jul 25, priced at $439 found 1 day ago
United
Tue, Aug 5 - Sun, Aug 10
SJO
Juan Santamaría Intl.
TYS
McGhee Tyson
$520 Roundtrip, found 1 day ago
$520
Roundtrip
found 1 day ago
Select United flight, departing Tue, Aug 5 from Juan Santamaría Intl. to McGhee Tyson, returning Sun, Aug 10, priced at $520 found 1 day ago

Cheap Flights to Middlesboro

Fall in love at first flight with your vacation to Middlesboro by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Middlesboro on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Middlesboro, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Middlesboro

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Middlesboro with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TYS airport.

What is the cheapest month to fly to Middlesboro?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Middlesboro are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Middlesboro?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Middlesboro.

What airport is best to fly into Middlesboro?

When you’re planning your trip to Middlesboro, convenience is the name of the game. Luckily, Middlesboro McGhee Tyson Airport is nearby so you can deplane and get going on checking off everything on your Middlesboro must-do list.

How much are flights to Middlesboro?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Middlesboro on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $203, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Middlesboro?

The trick to saving a stack of cash on your flight to Middlesboro? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $203 right now, why wait?

Middlesboro Flight Information
Destination airport
McGhee Tyson
Destination airport IATA code
TYS
Roundtrip price
$203

Last Minute Hotel Deals in Middlesboro

Sleep Inn & Suites
Sleep Inn & Suites
2.5 out of 5
1260 N, 12th Street, Middlesboro, KY
The price is $106 per night from May 11 to May 12
$106
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Middlesboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (702 reviews)
"Quiet"

Reviewed on Apr 7, 2025

Sleep Inn & Suites
Econo Lodge Middlesboro
Econo Lodge Middlesboro
2 out of 5
1623 Cumberland Avenue, Middlesboro, KY
The price is $100 per night from May 11 to May 12
$100
includes taxes & fees
May 11 - May 12
Stay at this motel in Middlesboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.8/10 (373 reviews)
"This property was very clean and fresh. Staff was very friendly and helpful. I would stay again"

Reviewed on Apr 14, 2025

Econo Lodge Middlesboro
Holiday Inn Express Middlesboro by IHG
Holiday Inn Express Middlesboro by IHG
2.5 out of 5
1252 N 12th St, Middlesboro, KY
The price is $131 per night from Apr 20 to Apr 21
$131
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Middlesboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (646 reviews)
"Staff was Kentucky friendly, professional & very helpful. Room was clean, bed & pillows first rate and comfortable. Morning free breakfast from 6 - 10 had all kinds of options - eggs, sausage, pancakes, a variety of cereal, yogurt and fresh fruit & juices. Great value for the price."

Reviewed on Apr 8, 2025

Holiday Inn Express Middlesboro by IHG
Holiday Inn Express Williamsburg by IHG
Holiday Inn Express Williamsburg by IHG
2.5 out of 5
56 West Highway 92, Williamsburg, KY
The price is $125 per night from May 4 to May 5
$125
includes taxes & fees
May 4 - May 5
Stay at this hotel in Williamsburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9/10 Wonderful! (938 reviews)
"It was a nice hotel, but there were suspected pet stains on the carpet in our room 420 as well as mold in the shower head, which is a health issue for those with mold allergies. Also the key cards to our room we had to constantly get redone every time we left the hotel."

Reviewed on Apr 13, 2025

Holiday Inn Express Williamsburg by IHG
Days Inn by Wyndham Jellico - Tennessee State Line
Days Inn by Wyndham Jellico - Tennessee State Line
2 out of 5
1417 5th Street, Jellico, TN
The price is $75 per night from Apr 17 to Apr 18
$75
includes taxes & fees
Apr 17 - Apr 18
Book a stay at this spa hotel in Jellico. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (934 reviews)
"Everything was good. Took a long time to get hot water."

Reviewed on Apr 12, 2025

Days Inn by Wyndham Jellico - Tennessee State Line
Pine Mountain State Resort Park
Pine Mountain State Resort Park
3 out of 5
1050 State Park Road, Pineville, KY
The price is $122 per night from Apr 16 to Apr 17
$122
includes taxes & fees
Apr 16 - Apr 17
Stay at this 3-star golf hotel in Pineville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (553 reviews)
"Great area, excellent staff, property is a little dated."

Reviewed on Apr 12, 2025

Pine Mountain State Resort Park
Cumberland Gap Inn
Cumberland Gap Inn
2.5 out of 5
630 Brooklyn Street, Cumberland Gap, TN
The price is $111 per night from Apr 16 to Apr 17
$111
includes taxes & fees
Apr 16 - Apr 17
Stay at this motel in Cumberland Gap. Enjoy free WiFi, free parking, and balconies or patios. Popular attractions Cumberland Gap National Historical Park and ...
7.8/10 Good! (562 reviews)
"Cool little town and the Inn was conveniently located to walk around."

Reviewed on Mar 31, 2025

Cumberland Gap Inn
Quality Inn
Quality Inn
2.5 out of 5
2608 South Highway 421, Harlan, KY
The price is $113 per night from May 4 to May 5
$113
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Harlan. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (292 reviews)
"Great place."

Reviewed on Apr 6, 2025

Quality Inn
See all 319 properties in Middlesboro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.