Search Cheap Flights to
Middlesboro

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Middlesboro Flights as Low as $183

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Jul 23 - Tue, Jul 29
LGA
LaGuardia
TYS
McGhee Tyson
$183 Roundtrip, found 4 hours ago
$183
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Wed, Jul 23 from LaGuardia to McGhee Tyson, returning Tue, Jul 29, priced at $183 found 4 hours ago
Bargain Flight
Sun, Aug 31 - Mon, Sep 8
ROC
Greater Rochester Intl.
TYS
McGhee Tyson
$209 Roundtrip, found 1 day ago
$209
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Sun, Aug 31 from Greater Rochester Intl. to McGhee Tyson, returning Mon, Sep 8, priced at $209 found 1 day ago
American Airlines
Thu, Jun 12 - Mon, Jun 16
MIA
Miami Intl.
TYS
McGhee Tyson
$233 Roundtrip, found 1 day ago
$233
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jun 12 from Miami Intl. to McGhee Tyson, returning Mon, Jun 16, priced at $233 found 1 day ago
American Airlines
Wed, Jun 25 - Tue, Jul 1
PVD
T.F. Green
TYS
McGhee Tyson
$238 Roundtrip, found 2 hours ago
$238
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Jun 25 from T.F. Green to McGhee Tyson, returning Tue, Jul 1, priced at $238 found 2 hours ago
Bargain Flight
Tue, Sep 9 - Wed, Sep 10
SYR
Hancock Intl.
TYS
McGhee Tyson
$238 Roundtrip, found 3 days ago
$238
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Tue, Sep 9 from Hancock Intl. to McGhee Tyson, returning Wed, Sep 10, priced at $238 found 3 days ago
Bargain Flight
Sat, Aug 30 - Wed, Sep 3
TPA
Tampa Intl.
TYS
McGhee Tyson
$241 Roundtrip, found 1 day ago
$241
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Sat, Aug 30 from Tampa Intl. to McGhee Tyson, returning Wed, Sep 3, priced at $241 found 1 day ago
Frontier Airlines
Thu, Aug 21 - Sun, Aug 24
PHL
Philadelphia Intl.
TYS
McGhee Tyson
$242 Roundtrip, found 1 day ago
$242
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Aug 21 from Philadelphia Intl. to McGhee Tyson, returning Sun, Aug 24, priced at $242 found 1 day ago
United
Tue, Oct 21 - Tue, Oct 28
AVP
Scranton Intl.
TYS
McGhee Tyson
$249 Roundtrip, found 15 hours ago
$249
Roundtrip
found 15 hours ago
Select United flight, departing Tue, Oct 21 from Scranton Intl. to McGhee Tyson, returning Tue, Oct 28, priced at $249 found 15 hours ago
American Airlines
Wed, Sep 3 - Sat, Sep 6
FLL
Fort Lauderdale - Hollywood Intl.
TYS
McGhee Tyson
$249 Roundtrip, found 1 hour ago
$249
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Wed, Sep 3 from Fort Lauderdale - Hollywood Intl. to McGhee Tyson, returning Sat, Sep 6, priced at $249 found 1 hour ago
Delta
Mon, Jul 7 - Tue, Jul 15
BTR
Baton Rouge Metropolitan
TYS
McGhee Tyson
$253 Roundtrip, found 1 day ago
$253
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Jul 7 from Baton Rouge Metropolitan to McGhee Tyson, returning Tue, Jul 15, priced at $253 found 1 day ago
American Airlines
Wed, Jun 11 - Sat, Jun 14
AUS
Austin-Bergstrom Intl.
TYS
McGhee Tyson
$259 Roundtrip, found 11 hours ago
$259
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Jun 11 from Austin-Bergstrom Intl. to McGhee Tyson, returning Sat, Jun 14, priced at $259 found 11 hours ago
Frontier Airlines
Thu, Jul 3 - Thu, Jul 10
DFW
Dallas-Fort Worth Intl.
TYS
McGhee Tyson
$264 Roundtrip, found 1 day ago
$264
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Jul 3 from Dallas-Fort Worth Intl. to McGhee Tyson, returning Thu, Jul 10, priced at $264 found 1 day ago
Frontier Airlines
Sat, Jun 7 - Thu, Jun 19
PHX
Sky Harbor Intl.
TYS
McGhee Tyson
$266 Roundtrip, just found
$266
Roundtrip
just found
Select Frontier Airlines flight, departing Sat, Jun 7 from Sky Harbor Intl. to McGhee Tyson, returning Thu, Jun 19, priced at $266 just found
Bargain Flight
Wed, Aug 6 - Sat, Aug 9
SJC
Norman Y. Mineta San Jose Intl.
TYS
McGhee Tyson
$274 Roundtrip, found 7 hours ago
$274
Roundtrip
found 7 hours ago
Select Bargain Flight flight, departing Wed, Aug 6 from Norman Y. Mineta San Jose Intl. to McGhee Tyson, returning Sat, Aug 9, priced at $274 found 7 hours ago
Frontier Airlines
Sun, Jul 20 - Sun, Jul 27
DTW
Detroit Metropolitan Wayne County
TYS
McGhee Tyson
$279 Roundtrip, found 3 days ago
$279
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sun, Jul 20 from Detroit Metropolitan Wayne County to McGhee Tyson, returning Sun, Jul 27, priced at $279 found 3 days ago
Frontier Airlines
Sun, Jun 8 - Sun, Jun 15
PDX
Portland Intl.
TYS
McGhee Tyson
$305 Roundtrip, found 3 days ago
$305
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sun, Jun 8 from Portland Intl. to McGhee Tyson, returning Sun, Jun 15, priced at $305 found 3 days ago

Cheap Flights to Middlesboro

Fall in love at first flight with your vacation to Middlesboro by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Middlesboro on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Middlesboro, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Middlesboro

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Middlesboro with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TYS airport.

What is the cheapest month to fly to Middlesboro?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Middlesboro are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Middlesboro?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 12 to choose from for your flight to Middlesboro.

What airport is best to fly into Middlesboro?

When you’re planning your trip to Middlesboro, convenience is the name of the game. Luckily, Middlesboro McGhee Tyson Airport is nearby so you can deplane and get going on checking off everything on your Middlesboro must-do list.

How much are flights to Middlesboro?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Middlesboro on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $183, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Middlesboro?

The trick to saving a stack of cash on your flight to Middlesboro? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $183 right now, why wait?

Middlesboro Flight Information
Destination airport
McGhee Tyson
Destination airport IATA code
TYS
Roundtrip price
$183

Last Minute Hotel Deals in Middlesboro

Sleep Inn & Suites
Sleep Inn & Suites
2.5 out of 5
1260 N, 12th Street, Middlesboro, KY
Book a stay at this business-friendly hotel in Middlesboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (725 reviews)
"The property is very clean, all staff were so polite and courteous. Breakfast was very nice. Quite location, nestled in the trees. The park is a few minutes away, several restaurants close by. Don’t miss out on the downtown food options. Sunset view from the front of the building was awesome."

Reviewed on May 26, 2025

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Sleep Inn & Suites
Econo Lodge Middlesboro
Econo Lodge Middlesboro
2 out of 5
1623 Cumberland Avenue, Middlesboro, KY
Stay at this motel in Middlesboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (386 reviews)
"Clean room!"

Reviewed on May 23, 2025

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Econo Lodge Middlesboro
Holiday Inn Express Middlesboro by IHG
Holiday Inn Express Middlesboro by IHG
2.5 out of 5
1252 N 12th St, Middlesboro, KY
Book a stay at this business-friendly hotel in Middlesboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (651 reviews)
"Seemed to be newly renovated. Everything was clean and comfortable. I have stayed all over the US. This stay was as enjoyable as they come. The staff was absolutely some of the friendliest anywhere. Definitely will be back."

Reviewed on May 18, 2025

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Holiday Inn Express Middlesboro by IHG
Boone Trail Inn
Boone Trail Inn
2 out of 5
2105 US HIGHWAY 25 E, Middlesboro, KY
Stay at this motel in Middlesboro. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions ...
7/10 Good! (91 reviews)
"Very Clean and Extremely Friendly Staff. Thanks for a Great Stay."

Reviewed on Apr 30, 2025

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Boone Trail Inn
Suburban Studios Middlesboro
Suburban Studios Middlesboro
2 out of 5
1623 Cumberland Avenue Building B, Middlesboro, KY
Stay at this hotel in Middlesboro. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Bell County Historical Society Museum and Middlesboro ...
7.8/10 Good! (48 reviews)
"Like another reviewer, I am not fond of motels with doors to the outside. However, she gave a good review so I decided to rent here. The room was very nice. Everything in it was fairly new and clean and no carpet. Love hard floors. Bathroom was very sparkling. Nice little kitchenette, although we ..."

Reviewed on Mar 2, 2025

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Suburban Studios Middlesboro
Holiday Inn Express Williamsburg by IHG
Holiday Inn Express Williamsburg by IHG
2.5 out of 5
56 West Highway 92, Williamsburg, KY
Stay at this hotel in Williamsburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9/10 Wonderful! (954 reviews)
"Nice overnight stay when driving north from Florida. Clean. Convenient from I75. I would stay here again."

Reviewed on May 20, 2025

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Holiday Inn Express Williamsburg by IHG
Pine Mountain State Resort Park
Pine Mountain State Resort Park
3 out of 5
1050 State Park Road, Pineville, KY
Stay at this 3-star golf hotel in Pineville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (561 reviews)
"There where workman the first day but it was better after they were finished"

Reviewed on May 18, 2025

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Pine Mountain State Resort Park
Days Inn by Wyndham Jellico - Tennessee State Line
Days Inn by Wyndham Jellico - Tennessee State Line
2 out of 5
1417 5th Street, Jellico, TN
Book a stay at this spa hotel in Jellico. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (950 reviews)
"The property was under construction, so it was hard to give a decent rating. The room was clean, and that is what mattered."

Reviewed on May 22, 2025

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Days Inn by Wyndham Jellico - Tennessee State Line
See all 321 properties in Middlesboro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.