Search Cheap Flights to
San Francisco

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Cheap Flights to San Francisco

Fall in love at first flight with your vacation to San Francisco by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to San Francisco on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in San Francisco, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to San Francisco

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to San Francisco with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the SYP airport.

What is the cheapest month to fly to San Francisco?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to San Francisco are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to San Francisco?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to San Francisco.

What airport is best to fly into San Francisco?

When you’re planning your trip to San Francisco, convenience is the name of the game. Luckily, San Francisco Alonso Valderrama Airport is nearby so you can deplane and get going on checking off everything on your San Francisco must-do list.

How much are flights to San Francisco?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to San Francisco on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to San Francisco?

The trick to saving a stack of cash on your flight to San Francisco? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

San Francisco Flight Information
Destination airport
San Francisco
Destination airport IATA code
SYP

Last Minute Hotel Deals in San Francisco

Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana, Santiago, Veraguas
Stay at this 3.5-star business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (314 reviews)
"Excellent place for family"

Reviewed on Jul 24, 2025

Hotel Gran David
Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas
Stay at this 3.5-star spa hotel in Nuevo Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Nacional Cerro Hoya and Cerámica ...
8.8/10 Excellent! (521 reviews)
Good hotel ran by a great staff!
"The staff was friendly and helpful. Pool is one of my favorites clean with a swim up bar. Good breakfast buffet. I was there for a graduation ceremony, a good facility for that as well."

Reviewed on Jul 13, 2025

Hotel Mykonos Panama
HOTEL VISTA LAGO

HOTEL VISTA LAGO

3 out of 5
Rincón Largo, La Pena, Santiago de Veraguas
Stay at this 3-star hotel in La Pena. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Acuatico Italia Guadalupe Panama and Omar ...
9.2/10 Wonderful! (65 reviews)
"Really a wonderful surprise and a beautiful and relaxing hotel. Food was well prices and super delicious:)"

Reviewed on Jul 21, 2025

HOTEL VISTA LAGO
Hotel Galería

Hotel Galería

3 out of 5
Vía Interamericana Santiago, Km 232.88, Nuevo Santiago
Stay at this 3-star business-friendly hotel in Nuevo Santiago. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions Plaza Banconal and Parque ...
8.2/10 Very Good! (189 reviews)
Perfect overnight stop
"We stayed over night on our way home from Panama City. I used the pool, very clean and refreshing. Everything was clean and comfortable. I couldn’t get hot water in the shower, but my son had no problem. The breakfast was excellent."

Reviewed on Jun 21, 2025

Hotel Galería
La Qhia Eco Retreat

La Qhia Eco Retreat

2.5 out of 5
Barriada el Cerro A 100 Mts De, Santa Fe, Veraguas
Stay at this hostal in Santa Fe. Enjoy free parking, breakfast (surcharge), and onsite spa services. Popular attractions Town Square and Catholic Church of Santa ...
7.8/10 Good! (18 reviews)
Nice stay in Santa Fe
"Our room had some drawbacks, like many gaps between the roof and walls that enable insects to go inside, but we used our own mosquito net and we were safe to sleep quietly. The second night ants invaded our room, we were offered to be moved to another room, but we were ok with the solution to spray ..."

Reviewed on Mar 17, 2025

La Qhia Eco Retreat
Hotel Plaza

Hotel Plaza

3 out of 5
Interamericana, Nuevo Santiago, Veraguas
Stay at this 3-star family-friendly hotel in Nuevo Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Parque Nacional Cerro ...
"It's a 35 $ a night hotel !!"

Reviewed on Aug 21, 2023

Hotel Plaza
Hotel Anachoreo

Hotel Anachoreo

3 out of 5
Calle Chinita, Santa Fe, Veraguas Province
Stay at this 3-star B&B in Santa Fe. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Town Square and Catholic Church of Santa Fe are located ...
9.4/10 Exceptional! (34 reviews)
Exquisite Casita
"Excellent accommodation: Room, grounds, and common area are beautifully decorated and spotless clean. Staff were friendly & helpful. Only problem was issue with hot water heater the day of our stay."

Reviewed on Apr 1, 2025

Hotel Anachoreo
Hotel La Hacienda

Hotel La Hacienda

3 out of 5
Via Interamericana, Rodrigo Luque, Veraguas
Stay at this 3-star family-friendly hotel in Rodrigo Luque. Enjoy free WiFi, free parking, and a casino. Popular attractions Parque Acuatico Italia Guadalupe ...
Real Hacienda feeling
"Hotel with lots of colors. Reception area is fantastic. Chairs, wall are painted with hundreds of colors. Calm hotel with polite staff."

Reviewed on Aug 2, 2016

Hotel La Hacienda
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.