Search Deals on
San Francisco Vacation Packages

Build your package with 2 more options

Leaving from

Going to

Departing

Returning

Travelers

Room 1

Adults

ChildrenAges 2 to 17

InfantsYounger than 2

Add specific hotel dates

San Francisco
Veraguas
Panama
Mexico and Central America
Hotwire.com

San Francisco Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Summit Rainforest & Golf Resort

4 out of 5

Price was $1,120, price is now $738 per person

$738

per person

Dec 1 - Dec 8

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this 4-star golf hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Centenario Bridge and Summit Botanical Gardens & Zoo are located nearby.

Central Hotel Panama Casco Viejo

4 out of 5

Save 100% on your flight

Price was $2,161, price is now $973 per person

$973

per person

Dec 1 - Dec 8

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Central Hotel Bocas del Toro

3 out of 5

Save 100% on your flight

Price was $2,468, price is now $1,348 per person

$1,348

per person

Nov 2 - Nov 6

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

Stay at this 3-star hotel in Bocas del Toro. Enjoy free breakfast, free WiFi, and a marina. Popular attractions Bolivar Park and Bocas del Toro Ferry Terminal are located nearby.

Mahogany Suites

2 out of 5

Price was $1,205, price is now $754 per person

$754

per person

Dec 1 - Dec 8

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this hotel in Arraijan. Enjoy free WiFi and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Bristol Panama, a Registry Collection Hotel

5 out of 5

Save 100% on your flight

Price was $1,791, price is now $1,126 per person

$1,126

per person

Dec 1 - Dec 8

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

Hotel Riu Plaza Panama

5 out of 5

Price was $1,310, price is now $843 per person

$843

per person

Dec 1 - Dec 8

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

The Sands by Wynwood House

2 out of 5

Save 100% on your flight

Price was $2,773, price is now $1,824 per person

$1,824

per person

Nov 2 - Nov 6

found 12 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi and an outdoor pool. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Las Americas Golden Tower Panama

4 out of 5

Price was $1,331, price is now $890 per person

$890

per person

Dec 1 - Dec 8

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.