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Santa Cruz

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Santa Cruz Flights as Low as $183

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Jetsmart SPA
Thu, May 21 - Sat, May 23
AEP
Aeroparque Jorge Newbery
SCL
Arturo Merino Benitez
$183 Roundtrip, found 3 hours ago
$183
Roundtrip
found 3 hours ago
Select Jetsmart SPA flight, departing Thu, May 21 from Aeroparque Jorge Newbery to Arturo Merino Benitez, returning Sat, May 23, priced at $183 found 3 hours ago
LATAM Airlines Group
Wed, May 13 - Wed, May 27
EZE
Ministro Pistarini Intl.
SCL
Arturo Merino Benitez
$194 Roundtrip, found 5 days ago
$194
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Wed, May 13 from Ministro Pistarini Intl. to Arturo Merino Benitez, returning Wed, May 27, priced at $194 found 5 days ago
Jetsmart SPA
Wed, Jun 10 - Wed, Jun 17
LIM
Jorge Chávez Intl.
SCL
Arturo Merino Benitez
$244 Roundtrip, found 7 hours ago
$244
Roundtrip
found 7 hours ago
Select Jetsmart SPA flight, departing Wed, Jun 10 from Jorge Chávez Intl. to Arturo Merino Benitez, returning Wed, Jun 17, priced at $244 found 7 hours ago
Jetsmart SPA
Sat, Jun 27 - Fri, Jul 3
GRU
Guarulhos - Governor André Franco Montoro Intl.
SCL
Arturo Merino Benitez
$313 Roundtrip, found 2 days ago
$313
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Sat, Jun 27 from Guarulhos - Governor André Franco Montoro Intl. to Arturo Merino Benitez, returning Fri, Jul 3, priced at $313 found 2 days ago
Arajet
Sun, Sep 13 - Mon, Sep 21
PUJ
Punta Cana Intl.
SCL
Arturo Merino Benitez
$464 Roundtrip, found 1 day ago
$464
Roundtrip
found 1 day ago
Select Arajet flight, departing Sun, Sep 13 from Punta Cana Intl. to Arturo Merino Benitez, returning Mon, Sep 21, priced at $464 found 1 day ago
Sky Airline Peru
Tue, Apr 21 - Tue, May 12
MIA
Miami Intl.
SCL
Arturo Merino Benitez
$510 Roundtrip, found 5 days ago
$510
Roundtrip
found 5 days ago
Select Sky Airline Peru flight, departing Tue, Apr 21 from Miami Intl. to Arturo Merino Benitez, returning Tue, May 12, priced at $510 found 5 days ago
Jetsmart SPA
Fri, Apr 10 - Tue, May 5
BAQ
Ernesto Cortissoz Intl.
SCL
Arturo Merino Benitez
$563 Roundtrip, found 3 days ago
$563
Roundtrip
found 3 days ago
Select Jetsmart SPA flight, departing Fri, Apr 10 from Ernesto Cortissoz Intl. to Arturo Merino Benitez, returning Tue, May 5, priced at $563 found 3 days ago
Copa
Thu, Apr 30 - Tue, May 5
JFK
John F. Kennedy Intl.
SCL
Arturo Merino Benitez
$653 Roundtrip, just found
$653
Roundtrip
just found
Select Copa flight, departing Thu, Apr 30 from John F. Kennedy Intl. to Arturo Merino Benitez, returning Tue, May 5, priced at $653 just found
American Airlines
Wed, Apr 8 - Sat, Apr 18
ORD
O'Hare Intl.
SCL
Arturo Merino Benitez
$744 Roundtrip, found 1 day ago
$744
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Apr 8 from O'Hare Intl. to Arturo Merino Benitez, returning Sat, Apr 18, priced at $744 found 1 day ago
Copa
Sat, Apr 18 - Sat, May 2
IAD
Washington Dulles Intl.
SCL
Arturo Merino Benitez
$773 Roundtrip, found 5 hours ago
$773
Roundtrip
found 5 hours ago
Select Copa flight, departing Sat, Apr 18 from Washington Dulles Intl. to Arturo Merino Benitez, returning Sat, May 2, priced at $773 found 5 hours ago
Delta
Sun, Aug 9 - Mon, Aug 17
SFO
San Francisco Intl.
SCL
Arturo Merino Benitez
$785 Roundtrip, found 7 hours ago
$785
Roundtrip
found 7 hours ago
Select Delta flight, departing Sun, Aug 9 from San Francisco Intl. to Arturo Merino Benitez, returning Mon, Aug 17, priced at $785 found 7 hours ago
Copa
Sat, Jun 6 - Sun, Jun 14
BWI
Baltimore Washington Intl. Thurgood Marshall
SCL
Arturo Merino Benitez
$786 Roundtrip, found 3 hours ago
$786
Roundtrip
found 3 hours ago
Select Copa flight, departing Sat, Jun 6 from Baltimore Washington Intl. Thurgood Marshall to Arturo Merino Benitez, returning Sun, Jun 14, priced at $786 found 3 hours ago
Delta
Mon, Jul 20 - Mon, Jul 27
PHX
Sky Harbor Intl.
SCL
Arturo Merino Benitez
$933 Roundtrip, found 6 days ago
$933
Roundtrip
found 6 days ago
Select Delta flight, departing Mon, Jul 20 from Sky Harbor Intl. to Arturo Merino Benitez, returning Mon, Jul 27, priced at $933 found 6 days ago
Copa
Wed, May 6 - Sat, May 23
LAS
Harry Reid Intl.
SCL
Arturo Merino Benitez
$951 Roundtrip, found 19 hours ago
$951
Roundtrip
found 19 hours ago
Select Copa flight, departing Wed, May 6 from Harry Reid Intl. to Arturo Merino Benitez, returning Sat, May 23, priced at $951 found 19 hours ago
Delta
Mon, Aug 10 - Mon, Aug 17
MFR
Rogue Valley Intl.
SCL
Arturo Merino Benitez
$980 Roundtrip, found 6 hours ago
$980
Roundtrip
found 6 hours ago
Select Delta flight, departing Mon, Aug 10 from Rogue Valley Intl. to Arturo Merino Benitez, returning Mon, Aug 17, priced at $980 found 6 hours ago
Delta
Sat, Jun 6 - Sun, Jun 14
DCA
Ronald Reagan Washington National
SCL
Arturo Merino Benitez
$1,014 Roundtrip, found 23 hours ago
$1,014
Roundtrip
found 23 hours ago
Select Delta flight, departing Sat, Jun 6 from Ronald Reagan Washington National to Arturo Merino Benitez, returning Sun, Jun 14, priced at $1,014 found 23 hours ago

Cheap Flights to Santa Cruz

Fall in love at first flight with your vacation to Santa Cruz by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Cruz

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the SCL airport.

What is the cheapest month to fly to Santa Cruz?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Cruz.

What airport is best to fly into Santa Cruz?

When you’re planning your trip to Santa Cruz, convenience is the name of the game. Luckily, Santa Cruz Arturo Merino Benitez Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz must-do list.

How much are flights to Santa Cruz?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $183, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz?

The trick to saving a stack of cash on your flight to Santa Cruz? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $183 right now, why wait?

Santa Cruz Flight Information
Destination airport
Arturo Merino Benitez
Destination airport IATA code
SCL
Roundtrip price
$182

Last Minute Hotel Deals in Santa Cruz

Santa Cruz Plaza

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286 Santa Cruz O'Higgins
Book a stay at this spa hotel in Santa Cruz. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (352 reviews)
Me parecio un lindo hotel, el Desayuno es muy completo tipico chileno. Creo que en el chek in deberian informar de las cosas con que cuenta el hotel y paseos, creo que tener que ir a otra oficina es una perdida de recursos. Nos toco una habitacion con tinaja la que disfrutamos es algo muy bueno, ...

Reviewed on Mar 20, 2026

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Santa Cruz Plaza
Hotel Cava Colchagua

Hotel Cava Colchagua

4 out of 5
Barreales´s Way Santa Cruz O'Higgins
Book a stay at this spa hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and an attached winery. Popular attractions Laura Hartwig Winery and Casino ...
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Hotel Cava Colchagua
Hotel Vendimia Parador

Hotel Vendimia Parador

3 out of 5
Camino Los Boldos SN Santa Cruz O'Higgins
Stay at this hotel in Santa Cruz. Enjoy free WiFi, free parking, and free grocery shopping service. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (84 reviews)
This is a lovely family run establishment in a small traditional building, the interior is delightfully decorated with antique curios. The grounds include a nice pool overlooked by a sun deck which affords views of the surrounding countryside. It also has secure parking. Our room was large and tastefully ...

Reviewed on Mar 19, 2026

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Hotel Vendimia Parador
TerraViña

TerraViña

3 out of 5
Camino Los Boldos S/n Santa Cruz O'Higgins
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Laura Hartwig Winery and Plaza ...
9.2/10 Wonderful! (213 reviews)
The hotel had a great buffet breakfast which was included with your stay. The staff were helpful and friendly would offer to book restaurant reservations. The only complaint was we found the air conditioner fan to loud.

Reviewed on Mar 12, 2026

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TerraViña
Hotel Boutique Vendimia Premium

Hotel Boutique Vendimia Premium

3.5 out of 5
Ismael Valdes 92 Santa Cruz O'Higgins
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Museo de Colchagua and Plaza ...
9.2/10 Wonderful! (139 reviews)
Lovely!!

Reviewed on Mar 18, 2026

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Hotel Boutique Vendimia Premium
La Perla Hotel

La Perla Hotel

3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía Santa Cruz O'Higgins
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo de Colchagua and Plaza ...
9.2/10 Wonderful! (110 reviews)
Excellent Staff, excellent facilities, and an excellent sleep in a very quiet location.

Reviewed on Feb 13, 2026

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La Perla Hotel
Hotel Boutique Grand Cru

Hotel Boutique Grand Cru

3 out of 5
Chomedahue, cruce El Guindo Santa Cruz O'Higgins
Stay at this hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo de Colchagua and Plaza de Armas are located ...
10/10 Exceptional! (12 reviews)
Great breakfast. Super host Juan Luis. Great location. Comfy bed. Spacious loft style rooms

Reviewed on Mar 29, 2026

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Hotel Boutique Grand Cru
Colchagua Tiny Lodge

Colchagua Tiny Lodge

3.5 out of 5
I-350 kilometro 4,5 Santa Cruz O'Higgins
Stay at this cabin in Santa Cruz. Enjoy free WiFi, free parking, and private hot tubs. Popular attractions Lapostolle Clos Apalta Winery and Bodega Viña Viu ...
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Colchagua Tiny Lodge
See all 56 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.