Search Cheap Flights to
Santa Cruz

Photo by Vivian Rennó

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Santa Cruz Flights as Low as $479

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

SKY AIRLINE
Thu, May 1 - Sun, May 11
MIA
Miami Intl.
SCL
Arturo Merino Benitez
$479 Roundtrip, found 1 day ago
$479
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Thu, May 1 from Miami Intl. to Arturo Merino Benitez, returning Sun, May 11, priced at $479 found 1 day ago
Delta
Thu, Mar 20 - Mon, Mar 31
MCO
Orlando Intl.
SCL
Arturo Merino Benitez
$519 Roundtrip, found 19 hours ago
$519
Roundtrip
found 19 hours ago
Select Delta flight, departing Thu, Mar 20 from Orlando Intl. to Arturo Merino Benitez, returning Mon, Mar 31, priced at $519 found 19 hours ago
Copa
Thu, Mar 20 - Mon, Mar 31
MCO
Orlando Intl.
SCL
Arturo Merino Benitez
$540 Roundtrip, found 19 hours ago
$540
Roundtrip
found 19 hours ago
Select Copa flight, departing Thu, Mar 20 from Orlando Intl. to Arturo Merino Benitez, returning Mon, Mar 31, priced at $540 found 19 hours ago
LATAM Airlines Group
Thu, Mar 20 - Mon, Mar 31
MCO
Orlando Intl.
SCL
Arturo Merino Benitez
$558 Roundtrip, found 19 hours ago
$558
Roundtrip
found 19 hours ago
Select LATAM Airlines Group flight, departing Thu, Mar 20 from Orlando Intl. to Arturo Merino Benitez, returning Mon, Mar 31, priced at $558 found 19 hours ago
avianca
Thu, May 1 - Sun, May 11
MIA
Miami Intl.
SCL
Arturo Merino Benitez
$559 Roundtrip, found 1 day ago
$559
Roundtrip
found 1 day ago
Select avianca flight, departing Thu, May 1 from Miami Intl. to Arturo Merino Benitez, returning Sun, May 11, priced at $559 found 1 day ago
Delta
Mon, Apr 14 - Tue, Apr 22
JFK
John F. Kennedy Intl.
SCL
Arturo Merino Benitez
$565 Roundtrip, found 2 days ago
$565
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Apr 14 from John F. Kennedy Intl. to Arturo Merino Benitez, returning Tue, Apr 22, priced at $565 found 2 days ago
Delta
Mon, Apr 28 - Mon, May 12
MIA
Miami Intl.
SCL
Arturo Merino Benitez
$624 Roundtrip, found 2 days ago
$624
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Apr 28 from Miami Intl. to Arturo Merino Benitez, returning Mon, May 12, priced at $624 found 2 days ago
Delta
Tue, Mar 18 - Mon, Apr 14
LAX
Los Angeles Intl.
SCL
Arturo Merino Benitez
$627 Roundtrip, found 18 hours ago
$627
Roundtrip
found 18 hours ago
Select Delta flight, departing Tue, Mar 18 from Los Angeles Intl. to Arturo Merino Benitez, returning Mon, Apr 14, priced at $627 found 18 hours ago
American Airlines
Thu, May 1 - Sun, May 11
MIA
Miami Intl.
SCL
Arturo Merino Benitez
$644 Roundtrip, found 1 day ago
$644
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, May 1 from Miami Intl. to Arturo Merino Benitez, returning Sun, May 11, priced at $644 found 1 day ago
Delta
Tue, May 6 - Tue, May 13
SFO
San Francisco Intl.
SCL
Arturo Merino Benitez
$684 Roundtrip, found 11 hours ago
$684
Roundtrip
found 11 hours ago
Select Delta flight, departing Tue, May 6 from San Francisco Intl. to Arturo Merino Benitez, returning Tue, May 13, priced at $684 found 11 hours ago
Air Canada
Wed, Feb 5 - Tue, Feb 11
JFK
John F. Kennedy Intl.
SCL
Arturo Merino Benitez
$732 Roundtrip, found 5 days ago
$732
Roundtrip
found 5 days ago
Select Air Canada flight, departing Wed, Feb 5 from John F. Kennedy Intl. to Arturo Merino Benitez, returning Tue, Feb 11, priced at $732 found 5 days ago
Air Canada
Mon, Mar 10 - Wed, Mar 19
BOS
Logan Intl.
SCL
Arturo Merino Benitez
$796 Roundtrip, found 1 day ago
$796
Roundtrip
found 1 day ago
Select Air Canada flight, departing Mon, Mar 10 from Logan Intl. to Arturo Merino Benitez, returning Wed, Mar 19, priced at $796 found 1 day ago
Delta
Tue, Mar 18 - Tue, Mar 25
PHX
Sky Harbor Intl.
SCL
Arturo Merino Benitez
$824 Roundtrip, just found
$824
Roundtrip
just found
Select Delta flight, departing Tue, Mar 18 from Sky Harbor Intl. to Arturo Merino Benitez, returning Tue, Mar 25, priced at $824 just found
United
Sat, Mar 15 - Tue, Mar 25
PHX
Sky Harbor Intl.
SCL
Arturo Merino Benitez
$864 Roundtrip, just found
$864
Roundtrip
just found
Select United flight, departing Sat, Mar 15 from Sky Harbor Intl. to Arturo Merino Benitez, returning Tue, Mar 25, priced at $864 just found
Copa
Tue, Feb 18 - Tue, Feb 25
GSP
Greenville-Spartanburg Intl.
SCL
Arturo Merino Benitez
$1,049 Roundtrip, found 1 day ago
$1,049
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, Feb 18 from Greenville-Spartanburg Intl. to Arturo Merino Benitez, returning Tue, Feb 25, priced at $1,049 found 1 day ago
Delta
Thu, May 22 - Thu, May 29
ATL
Hartsfield-Jackson Atlanta Intl.
SCL
Arturo Merino Benitez
$1,139 Roundtrip, found 17 hours ago
$1,139
Roundtrip
found 17 hours ago
Select Delta flight, departing Thu, May 22 from Hartsfield-Jackson Atlanta Intl. to Arturo Merino Benitez, returning Thu, May 29, priced at $1,139 found 17 hours ago

Cheap Flights to Santa Cruz

Fall in love at first flight with your vacation to Santa Cruz by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Cruz

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the SCL airport.

What is the cheapest month to fly to Santa Cruz?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Cruz.

What airport is best to fly into Santa Cruz?

When you’re planning your trip to Santa Cruz, convenience is the name of the game. Luckily, Santa Cruz Arturo Merino Benitez Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz must-do list.

How much are flights to Santa Cruz?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $479, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz?

The trick to saving a stack of cash on your flight to Santa Cruz? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $479 right now, why wait?

Santa Cruz Flight Information
Destination airport
Arturo Merino Benitez
Destination airport IATA code
SCL
Roundtrip price
$479

Last Minute Hotel Deals in Santa Cruz

Hotel Cava Colchagua
Hotel Cava Colchagua
4 out of 5
Barreales´s Way, 3km from Santa Cruz Square, Santa Cruz, O'Higgins
The price is $141 per night from Jan 26 to Jan 27
$141
includes taxes & fees
Jan 26 - Jan 27
Stay at this 4-star spa hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and an attached winery. Popular attractions Laura Hartwig Winery and Colchagua ...
8.8/10 Excellent! (143 reviews)
"Literally set in a vineyard the rooms could be twee being set in ( very large) upturned wine barrels, but is fun. Noting though that there really is no soundproofing so as we were pretty much the only people there perhaps things change with more guests"

Reviewed on Jan 19, 2025

Hotel Cava Colchagua
Santa Cruz Plaza
Santa Cruz Plaza
4 out of 5
Plaza De Armas 286, Santa Cruz, O'Higgins
The price is $144 per night from Jan 26 to Jan 27
$144
includes taxes & fees
Jan 26 - Jan 27
Stay at this 4-star spa hotel in Santa Cruz. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (297 reviews)
"The property is very well located. It is a beautiful building with comfortable rooms and a great service. Breakfast buffet is awesome. Never had a comparable experience in another other hotel. The amount of food and the variety was huge including chilean typical plates. The personnel is very helpful ..."

Reviewed on Dec 30, 2024

Santa Cruz Plaza
Casa Calfu
Casa Calfu
3 out of 5
21 de Mayo 552, Santa Cruz, OHiggins
The price is $91 per night from Jan 26 to Jan 27
$91
includes taxes & fees
Jan 26 - Jan 27
Stay at this 3-star B&B in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Plaza de Armas and Museo de Colchagua are located ...
9.6/10 Exceptional! (53 reviews)
"Lovely grounds, well appointed room, wonderful staff, lovely pool and abundant breakfast."

Reviewed on Feb 19, 2024

Casa Calfu
La Perla Hotel
La Perla Hotel
3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía, Santa Cruz, O'Higgins
The price is $126 per night from Jan 26 to Jan 27
$126
includes taxes & fees
Jan 26 - Jan 27
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo de Colchagua and Plaza ...
9/10 Wonderful! (86 reviews)
"Friendly staff, Quiet and Safe. Clean rooms. Hot tub and pool not available when we were there (spring time)."

Reviewed on Oct 24, 2024

La Perla Hotel
Hotel Boutique Solaz Bella Vista de Colchagua
Hotel Boutique Solaz Bella Vista de Colchagua
3 out of 5
San Pedro de Callihue Lote 5 J, Santa Cruz, O'Higgins
The price is $102 per night from Jan 26 to Jan 27
$102
includes taxes & fees
Jan 26 - Jan 27
Stay at this 3-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Laura Hartwig Winery and Plaza de Armas are ...
9.2/10 Wonderful! (95 reviews)
Nice Rural Place
"Great value for the money. You will need a car as nothing is walkable. Staff very friendly. Rooms on the frugal side yet super clean."

Reviewed on Jan 5, 2025

Hotel Boutique Solaz Bella Vista de Colchagua
Hotel Boutique Vendimia Premium
Hotel Boutique Vendimia Premium
3.5 out of 5
Ismael Valdes 92, Santa Cruz, O'Higgins
The price is $123 per night from Jan 26 to Jan 27
$123
includes taxes & fees
Jan 26 - Jan 27
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Museo de Colchagua and Plaza ...
9/10 Wonderful! (130 reviews)
Quirky but nice
"Good location. Antiques everywhere. Helpful staff. Nice to stay somewhere different."

Reviewed on Oct 5, 2024

Hotel Boutique Vendimia Premium
TerraViña
TerraViña
3 out of 5
Camino Los Boldos S/n, Santa Cruz, O'Higgins
The price is $180 per night from Jan 26 to Jan 27
$180
includes taxes & fees
Jan 26 - Jan 27
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Laura Hartwig Winery and Plaza ...
9.2/10 Wonderful! (188 reviews)
"Situated in the middle of wineries, away from the hustle bustle - TerraVina is a beautiful property with rooms with a balcony facing the Andes. There is a terrific winery just a 5 to 8 minute walk and three restaurants within 5 minutes, one located directly within the property."

Reviewed on Nov 18, 2024

TerraViña
Hotel Vendimia Parador
Hotel Vendimia Parador
3 out of 5
Camino Los Boldos SN, Santa Cruz, O'Higgins
The price is $92 per night from Feb 18 to Feb 19
$92
includes taxes & fees
Feb 18 - Feb 19
Stay at this 3-star hotel in Santa Cruz. Enjoy free WiFi, free parking, and free grocery shopping service. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (69 reviews)
"Beautiful garden, wonderful setting in the hotel and the room, great swimming pool and amazing and warm service by the owners, thank you for everything, great stay!"

Reviewed on Jan 7, 2025

Hotel Vendimia Parador
See all 63 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.