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Santa Cruz

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Santa Cruz Flights as Low as $146

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

SKY AIRLINE
Aerolineas Argentinas
SKY AIRLINE
LATAM Airlines Group
Aerolineas Argentinas
LATAM Airlines Group
SKY AIRLINE
SKY AIRLINE
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
Aerolineas Argentinas
Delta
Copa
Air Canada
American Airlines

Cheap Flights to Santa Cruz

Fall in love at first flight with your vacation to Santa Cruz by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Cruz

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the SCL airport.

What is the cheapest month to fly to Santa Cruz?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Cruz.

What airport is best to fly into Santa Cruz?

When you’re planning your trip to Santa Cruz, convenience is the name of the game. Luckily, Santa Cruz Arturo Merino Benitez Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz must-do list.

How much are flights to Santa Cruz?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $146, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz?

The trick to saving a stack of cash on your flight to Santa Cruz? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $146 right now, why wait?

Santa Cruz Flight Information
Destination airport
Arturo Merino Benitez
Destination airport IATA code
SCL
Roundtrip price
$146

Last Minute Hotel Deals in Santa Cruz

Santa Cruz Plaza
Santa Cruz Plaza
4 out of 5
Plaza De Armas 286, Santa Cruz, O'Higgins
The price is $122 per night from May 12 to May 13
$122
includes taxes & fees
May 12 - May 13
Stay at this 4-star spa hotel in Santa Cruz. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (309 reviews)
"It was great, spa, sauna and heated pool was nice touch"

Reviewed on Apr 19, 2025

Santa Cruz Plaza
Hotel Cava Colchagua
Hotel Cava Colchagua
4 out of 5
Barreales´s Way, 3km from Santa Cruz Square, Santa Cruz, O'Higgins
The price is $155 per night from Apr 29 to Apr 30
$155
includes taxes & fees
Apr 29 - Apr 30
Stay at this 4-star spa hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and an attached winery. Popular attractions Laura Hartwig Winery and Casino ...
8.8/10 Excellent! (153 reviews)
"Fun, interesting, pools ice cold, dogs barking all night. Still you don’t want to miss this opportunity."

Reviewed on Mar 29, 2025

Hotel Cava Colchagua
TerraViña
TerraViña
3 out of 5
Camino Los Boldos S/n, Santa Cruz, O'Higgins
The price is $126 per night from May 4 to May 5
$126
includes taxes & fees
May 4 - May 5
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Laura Hartwig Winery and Plaza ...
9.2/10 Wonderful! (193 reviews)
"Great hotel in the Colchagua valley. Rooms are spacious and clean. Grounds are beautiful and the pool is restful! Staff are friendly and always eager to help. The restaurant serves tasty food and many wine options."

Reviewed on Mar 8, 2025

TerraViña
Hotel Boutique Vendimia Premium
Hotel Boutique Vendimia Premium
3.5 out of 5
Ismael Valdes 92, Santa Cruz, O'Higgins
The price is $71 per night from Apr 24 to Apr 25
$71
includes taxes & fees
Apr 24 - Apr 25
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Museo de Colchagua and Plaza ...
9/10 Wonderful! (131 reviews)
Quirky but nice
"Good location. Antiques everywhere. Helpful staff. Nice to stay somewhere different."

Reviewed on Oct 5, 2024

Hotel Boutique Vendimia Premium
Hotel Vendimia Parador
Hotel Vendimia Parador
3 out of 5
Camino Los Boldos SN, Santa Cruz, O'Higgins
The price is $71 per night from May 1 to May 2
$71
includes taxes & fees
May 1 - May 2
Stay at this 3-star hotel in Santa Cruz. Enjoy free WiFi, free parking, and free grocery shopping service. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (74 reviews)
"Great place for a weekend of wines and relax. My gf and I really enjoyed the facilities, good breakfast, owners provide great customer service."

Reviewed on Mar 24, 2025

Hotel Vendimia Parador
La Perla Hotel
La Perla Hotel
3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía, Santa Cruz, O'Higgins
The price is $87 per night from Apr 24 to Apr 25
$87
includes taxes & fees
Apr 24 - Apr 25
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo de Colchagua and Plaza ...
9/10 Wonderful! (92 reviews)
"Nice stay"

Reviewed on Apr 13, 2025

La Perla Hotel
Hotel Boutique Grand Cru
Hotel Boutique Grand Cru
3 out of 5
Chomedahue, cruce El Guindo, 13, Santa Cruz, O'Higgins
The price is $112 per night from Apr 28 to Apr 29
$112
includes taxes & fees
Apr 28 - Apr 29
Stay at this 3-star hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo de Colchagua and Plaza de Armas are located ...
10/10 Exceptional! (3 reviews)
"We had such a wonderful stay! The staff was so attentive and the room was impeccable! I highly recommend this hotel."

Reviewed on Apr 14, 2025

Hotel Boutique Grand Cru
Hotel Boutique Solaz Bella Vista de Colchagua
Hotel Boutique Solaz Bella Vista de Colchagua
3 out of 5
San Pedro de Callihue Lote 5 J, Santa Cruz, O'Higgins
The price is $87 per night from May 5 to May 6
$87
includes taxes & fees
May 5 - May 6
Stay at this 3-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Laura Hartwig Winery and Plaza de Armas are ...
9.2/10 Wonderful! (96 reviews)
"Really recommended. Breakfast is very good, staff is amazing. A jewel close to the vineyards. Nice for romantic retreat."

Reviewed on Apr 20, 2025

Hotel Boutique Solaz Bella Vista de Colchagua
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.