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Santa Cruz

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Santa Cruz Flights as Low as $191

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Jetsmart SPA
SKY AIRLINE
Jetsmart SPA
Jetsmart SPA
Aerolineas Argentinas
LATAM Airlines Group
KLM
Sky Airline Peru
WestJet
Delta
American Airlines
Delta
Delta
Delta
American Airlines
American Airlines

Cheap Flights to Santa Cruz

Fall in love at first flight with your vacation to Santa Cruz by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Cruz

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the SCL airport.

What is the cheapest month to fly to Santa Cruz?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Cruz.

What airport is best to fly into Santa Cruz?

When you’re planning your trip to Santa Cruz, convenience is the name of the game. Luckily, Santa Cruz Arturo Merino Benitez Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz must-do list.

How much are flights to Santa Cruz?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $191, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz?

The trick to saving a stack of cash on your flight to Santa Cruz? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $191 right now, why wait?

Santa Cruz Flight Information
Destination airport
Arturo Merino Benitez
Destination airport IATA code
SCL
Roundtrip price
$190

Last Minute Hotel Deals in Santa Cruz

Santa Cruz Plaza
Santa Cruz Plaza
4 out of 5
Plaza De Armas 286, Santa Cruz, O'Higgins
The price is $152 per night from Apr 10 to Apr 11
$152
includes taxes & fees
Apr 10 - Apr 11
Stay at this 4-star spa hotel in Santa Cruz. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (304 reviews)
"Nice well located with bar and good restaurante"

Reviewed on Jan 26, 2025

Santa Cruz Plaza
Hotel Vendimia Parador
Hotel Vendimia Parador
3 out of 5
Camino Los Boldos SN, Santa Cruz, O'Higgins
The price is $98 per night from Mar 27 to Mar 28
$98
includes taxes & fees
Mar 27 - Mar 28
Stay at this 3-star hotel in Santa Cruz. Enjoy free WiFi, free parking, and free grocery shopping service. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (73 reviews)
"Great property, and nice room. Quite close to busy road so noisier than expected. Garden less 'special' than expected from earlier reviews and pool unavailable. Welcome from owner's adult children was 'functional' rather than warm (once again not as had expected from reviews). Return of owners on ..."

Reviewed on Mar 17, 2025

Hotel Vendimia Parador
Hotel Cava Colchagua
Hotel Cava Colchagua
4 out of 5
Barreales´s Way, 3km from Santa Cruz Square, Santa Cruz, O'Higgins
The price is $148 per night from Apr 17 to Apr 18
$148
includes taxes & fees
Apr 17 - Apr 18
Stay at this 4-star spa hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and an attached winery. Popular attractions Laura Hartwig Winery and Casino ...
8.8/10 Excellent! (148 reviews)
"Literally set in a vineyard the rooms could be twee being set in ( very large) upturned wine barrels, but is fun. Noting though that there really is no soundproofing so as we were pretty much the only people there perhaps things change with more guests"

Reviewed on Jan 19, 2025

Hotel Cava Colchagua
Hotel Boutique Vendimia Premium
Hotel Boutique Vendimia Premium
3.5 out of 5
Ismael Valdes 92, Santa Cruz, O'Higgins
The price is $89 per night from Mar 27 to Mar 28
$89
includes taxes & fees
Mar 27 - Mar 28
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Museo de Colchagua and Plaza ...
9/10 Wonderful! (131 reviews)
Quirky but nice
"Good location. Antiques everywhere. Helpful staff. Nice to stay somewhere different."

Reviewed on Oct 5, 2024

Hotel Boutique Vendimia Premium
La Perla Hotel
La Perla Hotel
3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía, Santa Cruz, O'Higgins
The price is $98 per night from Mar 27 to Mar 28
$98
includes taxes & fees
Mar 27 - Mar 28
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo de Colchagua and Plaza ...
9/10 Wonderful! (89 reviews)
"Friendly staff, Quiet and Safe. Clean rooms. Hot tub and pool not available when we were there (spring time)."

Reviewed on Oct 24, 2024

La Perla Hotel
TerraViña
TerraViña
3 out of 5
Camino Los Boldos S/n, Santa Cruz, O'Higgins
The price is $126 per night from Apr 13 to Apr 14
$126
includes taxes & fees
Apr 13 - Apr 14
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Laura Hartwig Winery and Plaza ...
9.2/10 Wonderful! (192 reviews)
"Great hotel in the Colchagua valley. Rooms are spacious and clean. Grounds are beautiful and the pool is restful! Staff are friendly and always eager to help. The restaurant serves tasty food and many wine options."

Reviewed on Mar 8, 2025

TerraViña
Hotel Boutique Solaz Bella Vista de Colchagua
Hotel Boutique Solaz Bella Vista de Colchagua
3 out of 5
San Pedro de Callihue Lote 5 J, Santa Cruz, O'Higgins
The price is $87 per night from Mar 27 to Mar 28
$87
includes taxes & fees
Mar 27 - Mar 28
Stay at this 3-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Laura Hartwig Winery and Plaza de Armas are ...
9.2/10 Wonderful! (95 reviews)
Nice Rural Place
"Great value for the money. You will need a car as nothing is walkable. Staff very friendly. Rooms on the frugal side yet super clean."

Reviewed on Jan 5, 2025

Hotel Boutique Solaz Bella Vista de Colchagua
Casa Calfu
Casa Calfu
3 out of 5
21 de Mayo 552, Santa Cruz, OHiggins
The price is $104 per night from Mar 30 to Mar 31
$104
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3-star B&B in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Plaza de Armas and Museo de Colchagua are located ...
9.6/10 Exceptional! (55 reviews)
"Cozy, very well kept property with excellent service"

Reviewed on Feb 25, 2025

Casa Calfu
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.